Inf2 (inverted formin 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Inf2 (inverted formin 2) Rattus norvegicus
Analyze
Symbol: Inf2
Name: inverted formin 2
RGD ID: 1308350
Description: Predicted to enable actin binding activity and small GTPase binding activity. Predicted to be involved in actin cytoskeleton organization. Predicted to act upstream of or within regulation of cellular component size and regulation of mitochondrial fission. Predicted to be located in perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate E and focal segmental glomerulosclerosis 5. Orthologous to human INF2 (inverted formin 2); INTERACTS WITH 1-naphthyl isothiocyanate; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: MODEL
Also known as: inverted formin, FH2 and WH2 domain containing; inverted formin-2; LOC362790; LOW QUALITY PROTEIN: inverted formin-2; RGD1308350; similar to hypothetical protein MGC13251
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26131,649,162 - 131,675,944 (+)NCBI
Rnor_6.0 Ensembl6137,164,535 - 137,177,622 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.06137,162,593 - 137,180,198 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06146,170,182 - 146,187,667 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.16137,437,320 - 137,637,548 (+)NCBI
Celera6129,206,114 - 129,210,267 (+)NCBICelera
Celera6129,210,433 - 129,223,633 (+)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:12477932   PMID:20023659   PMID:23349293  


Genomics

Comparative Map Data
Inf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26131,649,162 - 131,675,944 (+)NCBI
Rnor_6.0 Ensembl6137,164,535 - 137,177,622 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.06137,162,593 - 137,180,198 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06146,170,182 - 146,187,667 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.16137,437,320 - 137,637,548 (+)NCBI
Celera6129,206,114 - 129,210,267 (+)NCBICelera
Celera6129,210,433 - 129,223,633 (+)NCBICelera
Cytogenetic Map6q32NCBI
INF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl14104,681,146 - 104,722,535 (+)EnsemblGRCh38hg38GRCh38
GRCh3814104,689,618 - 104,722,535 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3714105,155,955 - 105,188,872 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614104,226,988 - 104,256,992 (+)NCBINCBI36hg18NCBI36
Build 3414104,246,059 - 104,256,985NCBI
Celera1485,211,992 - 85,241,995 (+)NCBI
Cytogenetic Map14q32.33NCBI
HuRef1485,353,176 - 85,383,080 (+)NCBIHuRef
CHM1_114105,093,644 - 105,123,708 (+)NCBICHM1_1
Inf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912112,555,121 - 112,581,991 (+)NCBIGRCm39mm39
GRCm39 Ensembl12112,555,218 - 112,581,991 (+)Ensembl
GRCm3812112,588,744 - 112,615,557 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12112,588,784 - 112,615,557 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712113,826,995 - 113,853,768 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612113,052,465 - 113,063,365 (+)NCBImm8
Celera12113,802,332 - 113,829,237 (+)NCBICelera
Cytogenetic Map12F1NCBI
Inf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555383,163,940 - 3,178,832 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555383,154,670 - 3,176,510 (+)NCBIChiLan1.0ChiLan1.0
INF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.114105,143,791 - 105,163,941 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14105,145,779 - 105,163,154 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01485,339,478 - 85,366,336 (+)NCBIMhudiblu_PPA_v0panPan3
INF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1872,275,209 - 72,284,991 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha871,774,391 - 71,791,628 (+)NCBI
ROS_Cfam_1.0872,543,585 - 72,560,033 (+)NCBI
UMICH_Zoey_3.1872,231,643 - 72,242,771 (+)NCBI
UMICH_Zoey_3.1872,226,504 - 72,231,172 (+)NCBI
UNSW_CanFamBas_1.0872,269,581 - 72,286,805 (+)NCBI
UU_Cfam_GSD_1.0872,659,616 - 72,686,357 (+)NCBI
Inf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086401,848,591 - 1,866,379 (-)NCBI
SpeTri2.0NW_004936621677,548 - 693,609 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INF2
(Sus scrofa - pig)
No map positions available.
INF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12482,628,339 - 82,658,879 (+)NCBI
ChlSab1.1 Ensembl2482,629,090 - 82,660,118 (+)Ensembl
Vero_WHO_p1.0NW_02366605370,049,678 - 70,080,143 (+)NCBI
Inf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624734555,188 - 577,930 (-)NCBI

Position Markers
RH127822  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26131,675,710 - 131,675,922 (+)MAPPER
Rnor_6.06137,180,260 - 137,180,471NCBIRnor6.0
Rnor_5.06146,187,437 - 146,187,648UniSTSRnor5.0
Celera6129,223,400 - 129,223,611UniSTS
RH 3.4 Map6782.5UniSTS
Cytogenetic Map6q32UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)668781170147991367Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)668781170147991367Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)688996335139410483Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)692879510137879510Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)699273921144273921Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)699273921144792678Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)6101207574147991367Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6104363890147991367Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6104381930138066274Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6111134524138065254Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6117355600147991367Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)6127286494144745573Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6127286494147249902Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6127286494147991367Rat
2312560Pur20Proteinuria QTL 202.10.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6130561943144745573Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6132652096138068606Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:454
Count of miRNA genes:213
Interacting mature miRNAs:255
Transcripts:ENSRNOT00000018225, ENSRNOT00000031962
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 24 9 6 10 6 19 2 29 5
Low 1 19 48 35 9 35 8 11 55 33 12 6 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008776333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005506354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005506355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005506356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005506357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005506358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005506359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005506360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC088245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000018225   ⟹   ENSRNOP00000018225
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl6137,164,535 - 137,177,622 (+)Ensembl
RefSeq Acc Id: XM_039113400   ⟹   XP_038969328
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26131,658,306 - 131,675,944 (+)NCBI
RefSeq Acc Id: XM_039113401   ⟹   XP_038969329
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26131,658,306 - 131,675,944 (+)NCBI
RefSeq Acc Id: XM_039113402   ⟹   XP_038969330
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26131,658,306 - 131,675,944 (+)NCBI
RefSeq Acc Id: XM_039113404   ⟹   XP_038969332
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26131,658,306 - 131,675,944 (+)NCBI
RefSeq Acc Id: XM_039113405   ⟹   XP_038969333
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26131,649,162 - 131,675,944 (+)NCBI
RefSeq Acc Id: XM_039113406   ⟹   XP_038969334
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26131,658,286 - 131,667,870 (+)NCBI
RefSeq Acc Id: XM_039113407   ⟹   XP_038969335
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26131,658,289 - 131,667,658 (+)NCBI
RefSeq Acc Id: XM_039113408   ⟹   XP_038969336
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26131,665,135 - 131,675,944 (+)NCBI
RefSeq Acc Id: XR_005506354
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26131,658,305 - 131,675,944 (+)NCBI
RefSeq Acc Id: XR_005506355
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26131,658,305 - 131,675,944 (+)NCBI
RefSeq Acc Id: XR_005506356
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26131,658,305 - 131,675,944 (+)NCBI
RefSeq Acc Id: XR_005506357
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26131,658,305 - 131,675,944 (+)NCBI
RefSeq Acc Id: XR_005506358
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26131,658,306 - 131,675,944 (+)NCBI
RefSeq Acc Id: XR_005506359
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26131,658,306 - 131,675,944 (+)NCBI
RefSeq Acc Id: XR_005506360
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26131,658,287 - 131,667,392 (+)NCBI
Reference Sequences
RefSeq Acc Id: ENSRNOP00000018225   ⟸   ENSRNOT00000018225
RefSeq Acc Id: XP_038969333   ⟸   XM_039113405
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038969334   ⟸   XM_039113406
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038969335   ⟸   XM_039113407
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038969328   ⟸   XM_039113400
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038969329   ⟸   XM_039113401
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038969330   ⟸   XM_039113402
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038969332   ⟸   XM_039113404
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038969336   ⟸   XM_039113408
- Peptide Label: isoform X8
Protein Domains
FH2   GBD/FH3   WH2

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308350 AgrOrtholog
Ensembl Genes ENSRNOG00000028650 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000018225 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018225 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.2220 UniProtKB/TrEMBL
  1.25.10.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7368069 IMAGE-MGC_LOAD
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  FH2_Formin UniProtKB/TrEMBL
  FH2_Formin_sf UniProtKB/TrEMBL
  FH3_dom UniProtKB/TrEMBL
  GBD/FH3_dom UniProtKB/TrEMBL
  GTPase-bd UniProtKB/TrEMBL
  Inf2 UniProtKB/TrEMBL
  WH2_dom UniProtKB/TrEMBL
MGC_CLONE MGC:109039 IMAGE-MGC_LOAD
NCBI Gene 362790 ENTREZGENE
PANTHER PTHR46345 UniProtKB/TrEMBL
Pfam Drf_FH3 UniProtKB/TrEMBL
  Drf_GBD UniProtKB/TrEMBL
  FH2 UniProtKB/TrEMBL
  WH2 UniProtKB/TrEMBL
PhenoGen Inf2 PhenoGen
PROSITE FH2 UniProtKB/TrEMBL
  GBD_FH3 UniProtKB/TrEMBL
  WH2 UniProtKB/TrEMBL
SMART Drf_FH3 UniProtKB/TrEMBL
  Drf_GBD UniProtKB/TrEMBL
  FH2 UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt E9PT22_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-13 Inf2  inverted formin 2  Inf2  inverted formin, FH2 and WH2 domain containing  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-11-22 Inf2  inverted formin, FH2 and WH2 domain containing  RGD1308350  similar to hypothetical protein MGC13251  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1308350  similar to hypothetical protein MGC13251  RGD1308350_predicted  similar to hypothetical protein MGC13251 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1308350_predicted  similar to hypothetical protein MGC13251 (predicted)  LOC362790_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362790_predicted  similar to hypothetical protein MGC13251 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL