Lnx1 (ligand of numb-protein X 1) - Rat Genome Database

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Gene: Lnx1 (ligand of numb-protein X 1) Rattus norvegicus
Analyze
Symbol: Lnx1
Name: ligand of numb-protein X 1
RGD ID: 1308159
Description: Predicted to enable PDZ domain binding activity; identical protein binding activity; and ubiquitin-protein transferase activity. Predicted to be involved in synapse maturation and ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm; hippocampal mossy fiber to CA3 synapse; and postsynapse. Orthologous to human LNX1 (ligand of numb-protein X 1); PARTICIPATES IN Notch signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: E3 ubiquitin-protein ligase LNX; ligand of numb-protein X 1, E3 ubiquitin protein ligase; LOC360926
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81433,868,517 - 33,971,217 (+)NCBIGRCr8
mRatBN7.21433,514,429 - 33,617,086 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1433,514,436 - 33,617,086 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1433,861,616 - 33,964,216 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01435,169,187 - 35,271,787 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01433,654,677 - 33,757,275 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01436,047,136 - 36,149,740 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1436,047,144 - 36,149,740 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01435,873,412 - 35,976,243 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41435,888,702 - 35,992,436 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11435,905,409 - 35,993,128 (+)NCBI
Celera1432,775,671 - 32,878,444 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9535908   PMID:11782429   PMID:11922143   PMID:16832352   PMID:31628376  


Genomics

Comparative Map Data
Lnx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81433,868,517 - 33,971,217 (+)NCBIGRCr8
mRatBN7.21433,514,429 - 33,617,086 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1433,514,436 - 33,617,086 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1433,861,616 - 33,964,216 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01435,169,187 - 35,271,787 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01433,654,677 - 33,757,275 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01436,047,136 - 36,149,740 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1436,047,144 - 36,149,740 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01435,873,412 - 35,976,243 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41435,888,702 - 35,992,436 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11435,905,409 - 35,993,128 (+)NCBI
Celera1432,775,671 - 32,878,444 (+)NCBICelera
Cytogenetic Map14p11NCBI
LNX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38453,459,301 - 53,652,477 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl453,459,301 - 53,701,405 (-)EnsemblGRCh38hg38GRCh38
GRCh37454,325,468 - 54,457,653 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36454,020,225 - 54,119,124 (-)NCBINCBI36Build 36hg18NCBI36
Build 34454,166,395 - 54,265,295NCBI
Celera451,823,913 - 51,955,241 (-)NCBICelera
Cytogenetic Map4q12NCBI
HuRef450,271,546 - 50,403,183 (-)NCBIHuRef
CHM1_1454,362,096 - 54,493,493 (-)NCBICHM1_1
T2T-CHM13v2.0456,946,519 - 57,139,835 (-)NCBIT2T-CHM13v2.0
Lnx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39574,753,108 - 74,865,203 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl574,753,108 - 74,863,573 (-)EnsemblGRCm39 Ensembl
GRCm38574,592,447 - 74,703,043 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl574,592,447 - 74,702,912 (-)EnsemblGRCm38mm10GRCm38
MGSCv37574,988,472 - 75,098,928 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36574,874,144 - 74,959,521 (-)NCBIMGSCv36mm8
Celera571,857,429 - 71,977,915 (-)NCBICelera
Cytogenetic Map5C3.3NCBI
cM Map539.52NCBI
Lnx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544717,155,236 - 17,265,067 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544717,154,026 - 17,265,067 (+)NCBIChiLan1.0ChiLan1.0
LNX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2376,237,493 - 76,349,633 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1476,442,505 - 76,554,582 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0470,374,106 - 70,497,058 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1476,844,338 - 77,050,270 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl476,911,082 - 77,050,270 (+)Ensemblpanpan1.1panPan2
LNX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11346,083,826 - 46,258,698 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1346,083,910 - 46,187,005 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1346,041,719 - 46,216,603 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01346,693,922 - 46,868,875 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1346,692,023 - 46,868,331 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11346,367,360 - 46,486,577 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01345,899,411 - 46,074,025 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01346,772,319 - 46,947,171 (-)NCBIUU_Cfam_GSD_1.0
Lnx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528529,992,486 - 30,103,251 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648216,190,940 - 16,287,185 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648216,194,736 - 16,361,765 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LNX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl840,232,839 - 40,369,929 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1840,232,837 - 40,473,101 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2842,352,706 - 42,518,723 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LNX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1714,887,003 - 15,072,382 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl714,971,513 - 15,071,771 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606615,749,276 - 15,947,093 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lnx1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476115,962,740 - 16,069,547 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476115,945,791 - 16,069,894 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lnx1
556 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:231
Count of miRNA genes:156
Interacting mature miRNAs:176
Transcripts:ENSRNOT00000003088
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14908897839057237Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)141759376142336881Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141762256142337007Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)141863134542337007Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
2324617Coatc2Coat color QTL 20.001coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)143076702539153750Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143088377768757901Rat

Markers in Region
RH130724  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21433,614,741 - 33,614,950 (+)MAPPERmRatBN7.2
Rnor_6.01436,147,396 - 36,147,604NCBIRnor6.0
Rnor_5.01435,973,731 - 35,973,939UniSTSRnor5.0
RGSC_v3.41435,990,092 - 35,990,300UniSTSRGSC3.4
Celera1432,876,100 - 32,876,308UniSTS
RH 3.4 Map14429.49UniSTS
Cytogenetic Map14p11UniSTS
RH131812  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21433,616,093 - 33,616,655 (+)MAPPERmRatBN7.2
Rnor_6.01436,148,748 - 36,149,309NCBIRnor6.0
Rnor_5.01435,975,083 - 35,975,644UniSTSRnor5.0
RGSC_v3.41435,991,444 - 35,992,005UniSTSRGSC3.4
Celera1432,877,452 - 32,878,013UniSTS
RH 3.4 Map14429.99UniSTS
Cytogenetic Map14p11UniSTS
RH134622  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21433,596,376 - 33,596,574 (+)MAPPERmRatBN7.2
Rnor_6.01436,129,033 - 36,129,230NCBIRnor6.0
Rnor_5.01435,955,368 - 35,955,565UniSTSRnor5.0
RGSC_v3.41435,971,729 - 35,971,926UniSTSRGSC3.4
Celera1432,857,739 - 32,857,936UniSTS
RH 3.4 Map14430.59UniSTS
Cytogenetic Map14p11UniSTS
RH137428  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21433,556,250 - 33,556,459 (+)MAPPERmRatBN7.2
Rnor_6.01436,088,959 - 36,089,167NCBIRnor6.0
Rnor_5.01435,915,240 - 35,915,448UniSTSRnor5.0
RGSC_v3.41435,930,517 - 35,930,725UniSTSRGSC3.4
Celera1432,817,444 - 32,817,651UniSTS
RH 3.4 Map14380.08UniSTS
Cytogenetic Map14p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 23 32 5
Low 14 27 11 19 11 8 11 34 35 34 11 8
Below cutoff 6 24 24 24 6 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC099101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC136253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU219399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU219400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU219401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU219402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU219403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU219404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU219405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU219406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000003088   ⟹   ENSRNOP00000003088
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1433,514,436 - 33,617,086 (+)Ensembl
Rnor_6.0 Ensembl1436,047,144 - 36,149,740 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000082183   ⟹   ENSRNOP00000069112
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1433,538,663 - 33,616,824 (+)Ensembl
Rnor_6.0 Ensembl1436,071,376 - 36,149,525 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000110346   ⟹   ENSRNOP00000083513
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1433,514,436 - 33,616,863 (+)Ensembl
RefSeq Acc Id: NM_001108358   ⟹   NP_001101828
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81433,868,571 - 33,971,217 (+)NCBI
mRatBN7.21433,514,436 - 33,617,086 (+)NCBI
Rnor_6.01436,047,144 - 36,149,740 (+)NCBI
Rnor_5.01435,873,412 - 35,976,243 (+)NCBI
RGSC_v3.41435,888,702 - 35,992,436 (+)RGD
Celera1432,775,671 - 32,878,444 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250902   ⟹   XP_006250964
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81433,868,517 - 33,970,982 (+)NCBI
mRatBN7.21433,514,429 - 33,616,851 (+)NCBI
Rnor_6.01436,047,136 - 36,149,505 (+)NCBI
Rnor_5.01435,873,412 - 35,976,243 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250903   ⟹   XP_006250965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81433,892,112 - 33,970,982 (+)NCBI
mRatBN7.21433,538,459 - 33,616,851 (+)NCBI
Rnor_6.01436,069,052 - 36,149,505 (+)NCBI
Rnor_5.01435,873,412 - 35,976,243 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250904   ⟹   XP_006250966
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81433,892,112 - 33,970,982 (+)NCBI
mRatBN7.21433,538,456 - 33,616,851 (+)NCBI
Rnor_6.01436,069,052 - 36,149,505 (+)NCBI
Rnor_5.01435,873,412 - 35,976,243 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039092174   ⟹   XP_038948102
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81433,868,517 - 33,970,982 (+)NCBI
mRatBN7.21433,514,429 - 33,616,851 (+)NCBI
RefSeq Acc Id: NP_001101828   ⟸   NM_001108358
- UniProtKB: B6RHI6 (UniProtKB/TrEMBL),   F7EWI3 (UniProtKB/TrEMBL),   B6RHI5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250964   ⟸   XM_006250902
- Peptide Label: isoform X1
- UniProtKB: B6RHI5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250966   ⟸   XM_006250904
- Peptide Label: isoform X3
- UniProtKB: B6RHI7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250965   ⟸   XM_006250903
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JUI7 (UniProtKB/TrEMBL),   A6JD15 (UniProtKB/TrEMBL),   B6RHI7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000069112   ⟸   ENSRNOT00000082183
RefSeq Acc Id: ENSRNOP00000003088   ⟸   ENSRNOT00000003088
RefSeq Acc Id: XP_038948102   ⟸   XM_039092174
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZXC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000083513   ⟸   ENSRNOT00000110346
Protein Domains
PDZ   RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B6RHI6-F1-model_v2 AlphaFold B6RHI6 1-728 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699283
Promoter ID:EPDNEW_R9808
Type:multiple initiation site
Name:Lnx1_2
Description:ligand of numb-protein X 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R9809  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01436,047,160 - 36,047,220EPDNEW
RGD ID:13699296
Promoter ID:EPDNEW_R9809
Type:multiple initiation site
Name:Lnx1_1
Description:ligand of numb-protein X 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R9808  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01436,071,334 - 36,071,394EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308159 AgrOrtholog
BioCyc Gene G2FUF-15917 BioCyc
Ensembl Genes ENSRNOG00000002272 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003088 ENTREZGENE
  ENSRNOT00000003088.6 UniProtKB/TrEMBL
  ENSRNOT00000082183.2 UniProtKB/TrEMBL
  ENSRNOT00000110346.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro PDZ/DHR/GLGF UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report rno:360926 UniProtKB/TrEMBL
NCBI Gene 360926 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE LNX UniProtKB/TrEMBL
  MULTIPLE PDZ DOMAIN PROTEIN UniProtKB/TrEMBL
Pfam PDZ UniProtKB/TrEMBL
  zf-C3HC4_3 UniProtKB/TrEMBL
PhenoGen Lnx1 PhenoGen
PROSITE PDZ UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002272 RatGTEx
SMART PDZ UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
Superfamily-SCOP PDZ UniProtKB/TrEMBL
  RING/U-box UniProtKB/TrEMBL
UniProt A0A0G2JUI7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZXC4 ENTREZGENE, UniProtKB/TrEMBL
  A6JD15 ENTREZGENE, UniProtKB/TrEMBL
  B6RHI0_RAT UniProtKB/TrEMBL
  B6RHI1_RAT UniProtKB/TrEMBL
  B6RHI5 ENTREZGENE, UniProtKB/TrEMBL
  B6RHI6 ENTREZGENE, UniProtKB/TrEMBL
  B6RHI7 ENTREZGENE, UniProtKB/TrEMBL
  F7EWI3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-13 Lnx1  ligand of numb-protein X 1  Lnx1  ligand of numb-protein X 1, E3 ubiquitin protein ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-19 Lnx1  ligand of numb-protein X 1, E3 ubiquitin protein ligase  Lnx1  ligand of numb-protein X 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Lnx1  ligand of numb-protein X 1   Lnx1_predicted  ligand of numb-protein X 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Lnx1_predicted  ligand of numb-protein X 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED