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Gene: Shoc2 (SHOC2 leucine-rich repeat scaffold protein) Rattus norvegicus
Symbol: Shoc2
Name: SHOC2 leucine-rich repeat scaffold protein
Description: Predicted to have protein phosphatase 1 binding activity. Predicted to be involved in positive regulation of Ras protein signal transduction. Predicted to localize to the cytosol; nucleoplasm; and protein phosphatase type 1 complex. Orthologous to human SHOC2 (SHOC2 leucine rich repeat scaffold protein); INTERACTS WITH bisphenol A; ketamine; rotenone.
Type: protein-coding
Also known as: leucine-rich repeat protein SHOC-2; LOC309548; protein soc-2 homolog; protein sur-8 homolog; soc-2 (suppressor of clear) homolog; soc-2 (suppressor of clear) homolog (C. elegans); soc-2 suppressor of clear homolog; soc-2 suppressor of clear homolog (C. elegans)
Homo sapiens (human) : SHOC2 (SHOC2 leucine rich repeat scaffold protein)  HGNC  Alliance
Mus musculus (house mouse) : Shoc2 (Shoc2, leucine rich repeat scaffold protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Shoc2 (SHOC2 leucine rich repeat scaffold protein)
Pan paniscus (bonobo/pygmy chimpanzee) : SHOC2 (SHOC2 leucine rich repeat scaffold protein)
Canis lupus familiaris (dog) : SHOC2 (SHOC2 leucine rich repeat scaffold protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Shoc2 (SHOC2 leucine rich repeat scaffold protein)
Sus scrofa (pig) : SHOC2 (SHOC2 leucine rich repeat scaffold protein)
Chlorocebus sabaeus (African green monkey) : SHOC2 (SHOC2 leucine rich repeat scaffold protein)
Heterocephalus glaber (naked mole-rat) : Shoc2 (SHOC2 leucine rich repeat scaffold protein)
more info ...
Is Marker For: Strains:   F344.GK-(D1Swe8-D1Gpam-1)/Swe  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01274,700,621 - 274,751,195 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1274,688,580 - 274,751,816 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01282,112,968 - 282,163,542 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41260,255,253 - 260,273,170 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11260,429,356 - 260,484,216 (+)NCBI
Celera1248,709,991 - 248,759,976 (+)NCBICelera
Cytogenetic Map1q55NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Shoc2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308146
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.