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Gene: Nfu1 (NFU1 iron-sulfur cluster scaffold) Rattus norvegicus
Symbol: Nfu1
Name: NFU1 iron-sulfur cluster scaffold
RGD ID: 1307823
Description: Predicted to have 4 iron, 4 sulfur cluster binding activity and iron ion binding activity. Predicted to be involved in iron-sulfur cluster assembly and protein maturation by iron-sulfur cluster transfer. Predicted to localize to cytosol; mitochondrion; and nucleoplasm. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 1. Orthologous to human NFU1 (NFU1 iron-sulfur cluster scaffold); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; INTERACTS WITH bisphenol A; cocaine; dieldrin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Hirip5; histone cell cycle regulation defective interacting protein 5; LOC297416; NFU1 iron-sulfur cluster scaffold homolog; NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae); NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
Homo sapiens (human) : NFU1 (NFU1 iron-sulfur cluster scaffold)  HGNC  Alliance
Mus musculus (house mouse) : Nfu1 (NFU1 iron-sulfur cluster scaffold)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfu1 (NFU1 iron-sulfur cluster scaffold)
Pan paniscus (bonobo/pygmy chimpanzee) : NFU1 (NFU1 iron-sulfur cluster scaffold)
Canis lupus familiaris (dog) : NFU1 (NFU1 iron-sulfur cluster scaffold)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfu1 (NFU1 iron-sulfur cluster scaffold)
Sus scrofa (pig) : NFU1 (NFU1 iron-sulfur cluster scaffold)
Chlorocebus sabaeus (African green monkey) : NFU1 (NFU1 iron-sulfur cluster scaffold)
Heterocephalus glaber (naked mole-rat) : Nfu1 (NFU1 iron-sulfur cluster scaffold)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04118,814,284 - 118,834,955 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4118,814,284 - 118,834,955 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04183,383,769 - 183,404,239 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44121,184,017 - 121,187,110 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14121,401,604 - 121,432,159 (+)NCBI
Celera4108,428,818 - 108,449,350 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Nfu1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307823
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.