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Gene: Nfu1 (NFU1 iron-sulfur cluster scaffold) Rattus norvegicus
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Symbol: Nfu1
Name: NFU1 iron-sulfur cluster scaffold
RGD ID: 1307823
Description: Predicted to have 4 iron, 4 sulfur cluster binding activity and iron ion binding activity. Predicted to be involved in iron-sulfur cluster assembly and protein maturation by iron-sulfur cluster transfer. Predicted to localize to cytosol; mitochondrion; and nucleoplasm. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 1. Orthologous to human NFU1 (NFU1 iron-sulfur cluster scaffold); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; INTERACTS WITH bisphenol A; cocaine; dieldrin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Hirip5; histone cell cycle regulation defective interacting protein 5; LOC297416; NFU1 iron-sulfur cluster scaffold homolog; NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae); NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
Orthologs:
Homo sapiens (human) : NFU1 (NFU1 iron-sulfur cluster scaffold)  HGNC  Alliance
Mus musculus (house mouse) : Nfu1 (NFU1 iron-sulfur cluster scaffold)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfu1 (NFU1 iron-sulfur cluster scaffold)
Pan paniscus (bonobo/pygmy chimpanzee) : NFU1 (NFU1 iron-sulfur cluster scaffold)
Canis lupus familiaris (dog) : NFU1 (NFU1 iron-sulfur cluster scaffold)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfu1 (NFU1 iron-sulfur cluster scaffold)
Sus scrofa (pig) : NFU1 (NFU1 iron-sulfur cluster scaffold)
Chlorocebus sabaeus (African green monkey) : NFU1 (NFU1 iron-sulfur cluster scaffold)
Heterocephalus glaber (naked mole-rat) : Nfu1 (NFU1 iron-sulfur cluster scaffold)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04118,814,284 - 118,834,955 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4118,814,284 - 118,834,955 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04183,383,769 - 183,404,239 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44121,184,017 - 121,187,110 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14121,401,604 - 121,432,159 (+)NCBI
Celera4108,428,818 - 108,449,350 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Nfu1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307823
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.