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Gene: Nsd1 (nuclear receptor binding SET domain protein 1) Rattus norvegicus
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Symbol: Nsd1
Name: nuclear receptor binding SET domain protein 1
Description: Predicted to have several functions, including histone-lysine N-methyltransferase activity; nuclear hormone receptor binding activity; and transcription corepressor activity. Predicted to be involved in several processes, including regulation of RNA polymerase II regulatory region sequence-specific DNA binding activity; regulation of protein modification process; and regulation of transcription, DNA-templated. Predicted to localize to the chromatin and nucleus. Human ortholog(s) of this gene implicated in Sotos syndrome; acute myeloid leukemia; microcephaly; and neuroblastoma. Orthologous to human NSD1 (nuclear receptor binding SET domain protein 1); PARTICIPATES IN histone modification pathway; lysine degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific; LOC306764
Orthologs:
Homo sapiens (human) : NSD1 (nuclear receptor binding SET domain protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Nsd1 (nuclear receptor-binding SET-domain protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nsd1 (nuclear receptor binding SET domain protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NSD1 (nuclear receptor binding SET domain protein 1)
Canis lupus familiaris (dog) : NSD1 (nuclear receptor binding SET domain protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nsd1 (nuclear receptor binding SET domain protein 1)
Sus scrofa (pig) : NSD1 (nuclear receptor binding SET domain protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0179,840,859 - 9,955,391 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,844,133 - 9,952,898 (-)Ensembl
Rnor_5.01711,950,539 - 12,065,042 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41715,362,482 - 15,471,961 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11715,363,376 - 15,471,151 (-)NCBI
Celera179,393,607 - 9,502,492 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Nsd1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307748
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.