Gene: Pak4 (p21 (RAC1) activated kinase 4) Rattus norvegicus
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Symbol: Pak4
Name: p21 (RAC1) activated kinase 4
Description: ENCODES a protein that exhibits protein kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN cellular response to organic cyclic compound (ortholog); dendritic spine development (ortholog); negative regulation of endothelial cell apoptotic process (ortholog); PARTICIPATES IN fibroblast growth factor signaling pathway; epidermal growth factor/neuregulin signaling pathway; renal cell carcinoma pathway; ASSOCIATED WITH clear cell renal cell carcinoma (ortholog); Mammary Neoplasms, Experimental (ortholog); prostate cancer (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; bisphenol A
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC292756; p21 (CDKN1A)-activated kinase 4; p21 protein (Cdc42/Rac)-activated kinase 4; p21-activated kinase 4; serine/threonine-protein kinase PAK 4
Orthologs:
Homo sapiens (human) : PAK4 (p21 (RAC1) activated kinase 4)  HGNC  Alliance
Mus musculus (house mouse) : Pak4 (p21 (RAC1) activated kinase 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pak4 (p21 (RAC1) activated kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PAK4 (p21 (RAC1) activated kinase 4)
Canis lupus familiaris (dog) : PAK4 (p21 (RAC1) activated kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pak4 (p21 (RAC1) activated kinase 4)
Sus scrofa (pig) : PAK4 (p21 (RAC1) activated kinase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0185,162,462 - 85,201,746 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0186,378,296 - 86,417,580 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4183,670,786 - 83,710,070 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1183,749,728 - 83,797,056 (-)NCBI
Celera178,244,198 - 78,283,501 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pak4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307705
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE