Hrnr (hornerin) - Rat Genome Database

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Gene: Hrnr (hornerin) Rattus norvegicus
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Symbol: Hrnr
Name: hornerin
RGD ID: 1307660
Description: Predicted to be involved in cell envelope organization and establishment of skin barrier. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in keratohyalin granule and perinuclear region of cytoplasm. Predicted to be active in cornified envelope. Orthologous to human HRNR (hornerin); INTERACTS WITH 1,2-dichloroethane (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 2-hydroxypropanoic acid (ortholog).
Type: protein-coding
Previously known as: LOC310587; RGD1307660; similar to hornerin
RGD Orthologs
Human
Mouse
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Genome Annotation Status: not in current annotation release
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02193,626,283 - 193,639,848 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2193,627,243 - 193,634,181 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02211,227,940 - 211,239,721 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42186,393,623 - 186,405,265 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12186,342,966 - 186,355,371 (+)NCBI
Celera2171,314,820 - 171,318,755 (-)NCBICelera
Cytogenetic Map2q34NCBI


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11572870   PMID:21282207   PMID:21362503   PMID:21630459   PMID:21700703   PMID:23376485   PMID:23403047   PMID:24029230  


Genomics

Comparative Map Data
Hrnr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02193,626,283 - 193,639,848 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2193,627,243 - 193,634,181 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02211,227,940 - 211,239,721 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42186,393,623 - 186,405,265 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12186,342,966 - 186,355,371 (+)NCBI
Celera2171,314,820 - 171,318,755 (-)NCBICelera
Cytogenetic Map2q34NCBI
HRNR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381152,212,076 - 152,224,193 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1152,212,076 - 152,224,193 (-)EnsemblGRCh38hg38GRCh38
GRCh371152,184,552 - 152,196,669 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361150,451,182 - 150,463,293 (-)NCBINCBI36Build 36hg18NCBI36
Celera1125,299,240 - 125,308,530 (-)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1123,561,504 - 123,570,799 (-)NCBIHuRef
CHM1_11153,579,878 - 153,592,041 (-)NCBICHM1_1
Hrnr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39393,227,056 - 93,240,879 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl393,227,056 - 93,240,877 (+)EnsemblGRCm39 Ensembl
GRCm38393,319,749 - 93,333,572 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl393,319,749 - 93,333,570 (+)EnsemblGRCm38mm10GRCm38
MGSCv37393,123,671 - 93,137,494 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36393,405,958 - 93,418,975 (+)NCBIMGSCv36mm8
Celera393,772,386 - 93,778,017 (-)NCBICelera
Celera395,066,507 - 95,070,752 (-)NCBICelera
Cytogenetic Map3F2.1NCBI
HRNR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1197,350,236 - 97,362,876 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01127,570,653 - 127,583,285 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
LOC119863999
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ROS_Cfam_1.01762,211,458 - 62,220,185 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11761,039,431 - 61,048,151 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01761,126,410 - 61,133,175 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01761,854,570 - 61,863,299 (-)NCBIUU_Cfam_GSD_1.0
HRNR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1496,983,596 - 96,992,606 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
HRNR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12011,439,492 - 11,442,174 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603810,984,280 - 10,996,449 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 6
Low 1 1 3 2 6 1 1
Below cutoff 1 17 7 12 7 4 4 8 5 5 3 4

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008761274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000082934   ⟹   ENSRNOP00000072004
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2193,627,243 - 193,634,181 (+)Ensembl
RefSeq Acc Id: XM_008761274   ⟹   XP_008759496
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02193,626,283 - 193,639,848 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017596325   ⟹   XP_017451814
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera2171,314,820 - 171,318,755 (-)NCBI
Sequence:
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K1V9-F1-model_v2 AlphaFold A0A0G2K1V9 1-876 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307660 AgrOrtholog
Ensembl Genes ENSRNOG00000053250 Ensembl
NCBI Gene 310587 ENTREZGENE
PhenoGen Hrnr PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-09 Hrnr  hornerin  RGD1307660  similar to hornerin  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1307660  similar to hornerin   RGD1307660_predicted  similar to hornerin (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1307660_predicted  similar to hornerin (predicted)  LOC310587_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC310587_predicted  similar to hornerin (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL