Med15 (mediator complex subunit 15) - Rat Genome Database

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Gene: Med15 (mediator complex subunit 15) Rattus norvegicus
Analyze
Symbol: Med15
Name: mediator complex subunit 15
RGD ID: 1307560
Description: Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within somatic stem cell population maintenance. Predicted to be located in nucleoplasm. Predicted to be part of core mediator complex. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human MED15 (mediator complex subunit 15); PARTICIPATES IN RNA polymerase II transcription pathway; schizophrenia pathway; INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC360743; mediator of RNA polymerase II transcription subunit 15; Pcqap; positive cofactor 2, multiprotein complex, glutamine/Q-rich-associated protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21183,280,722 - 83,356,006 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1183,280,762 - 83,355,362 (+)Ensembl
Rnor_6.01187,553,868 - 87,628,631 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,553,868 - 87,628,502 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01190,606,469 - 90,681,242 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,270,503 - 85,344,999 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11185,299,560 - 85,384,726 (+)NCBI
Celera1182,052,699 - 82,127,011 (+)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Association study between CAG trinucleotide repeats in the PCQAP gene (PC2 glutamine/Q-rich-associated protein) and schizophrenia. De Luca A, etal., Am J Med Genet B Neuropsychiatr Genet 2003 Jan 1;116(1):32-5.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. The Mediator complex and transcription regulation. Poss ZC, etal., Crit Rev Biochem Mol Biol. 2013 Nov-Dec;48(6):575-608. doi: 10.3109/10409238.2013.840259. Epub 2013 Oct 3.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:19946888   PMID:20720539  


Genomics

Comparative Map Data
Med15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21183,280,722 - 83,356,006 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1183,280,762 - 83,355,362 (+)Ensembl
Rnor_6.01187,553,868 - 87,628,631 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,553,868 - 87,628,502 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01190,606,469 - 90,681,242 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,270,503 - 85,344,999 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11185,299,560 - 85,384,726 (+)NCBI
Celera1182,052,699 - 82,127,011 (+)NCBICelera
Cytogenetic Map11q23NCBI
MED15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382220,507,610 - 20,587,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2220,495,913 - 20,587,632 (+)EnsemblGRCh38hg38GRCh38
GRCh372220,861,897 - 20,941,906 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362219,191,886 - 19,271,919 (+)NCBINCBI36hg18NCBI36
Build 342219,186,439 - 19,266,472NCBI
Celera224,352,845 - 4,432,848 (+)NCBI
Cytogenetic Map22q11.21NCBI
HuRef224,129,649 - 4,209,632 (+)NCBIHuRef
CHM1_12220,862,630 - 20,942,640 (+)NCBICHM1_1
T2T-CHM13v2.02220,916,219 - 20,996,263 (+)NCBI
Med15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391617,469,072 - 17,540,811 (-)NCBIGRCm39mm39
GRCm39 Ensembl1617,469,072 - 17,550,755 (-)Ensembl
GRCm381617,651,208 - 17,722,947 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1617,651,208 - 17,732,891 (-)EnsemblGRCm38mm10GRCm38
MGSCv371617,651,314 - 17,723,023 (-)NCBIGRCm37mm9NCBIm37
MGSCv361617,564,785 - 17,611,257 (-)NCBImm8
Celera1618,224,459 - 18,296,014 (-)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1610.94NCBI
Med15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544219,112,270 - 19,179,742 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544219,112,269 - 19,179,742 (+)NCBIChiLan1.0ChiLan1.0
MED15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12219,191,880 - 19,272,884 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2219,192,156 - 19,271,965 (+)Ensemblpanpan1.1panPan2
MED15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12630,299,424 - 30,368,460 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2630,299,442 - 30,367,572 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2630,258,317 - 30,327,156 (+)NCBI
ROS_Cfam_1.02631,707,993 - 31,776,853 (+)NCBI
ROS_Cfam_1.0 Ensembl2631,707,980 - 31,776,849 (+)Ensembl
UMICH_Zoey_3.12629,753,891 - 29,822,740 (+)NCBI
UNSW_CanFamBas_1.02629,378,095 - 29,446,935 (+)NCBI
UU_Cfam_GSD_1.02630,467,664 - 30,536,521 (+)NCBI
Med15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118139,973,141 - 140,067,071 (+)NCBI
SpeTri2.0NW_0049366192,687,004 - 2,780,898 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MED15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1450,703,019 - 50,759,310 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11450,703,010 - 50,759,310 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21454,266,459 - 54,318,847 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MED15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1195,111,512 - 5,195,677 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl195,112,435 - 5,167,139 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660851,741,216 - 1,826,089 (+)NCBIVero_WHO_p1.0
Med15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624945488,396 - 562,084 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
BE097295  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21183,355,908 - 83,356,091 (-)MAPPERmRatBN7.2
Rnor_6.01187,553,130 - 87,553,312NCBIRnor6.0
Rnor_5.01190,605,752 - 90,605,934UniSTSRnor5.0
RGSC_v3.41185,345,555 - 85,345,737UniSTSRGSC3.4
Celera1182,127,567 - 82,127,749UniSTS
RH 3.4 Map11699.9UniSTS
Cytogenetic Map11q23UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
2302043Pia27Pristane induced arthritis QTL 2718.60.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)118256654583440803Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:109
Count of miRNA genes:93
Interacting mature miRNAs:98
Transcripts:ENSRNOT00000002568
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 34 48 33 19 33 2 67 31 40 11
Low 9 9 8 8 8 9 7 4 1 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000002568   ⟹   ENSRNOP00000002568
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1183,280,762 - 83,355,362 (+)Ensembl
Rnor_6.0 Ensembl1187,553,868 - 87,628,502 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000098103   ⟹   ENSRNOP00000091727
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1183,280,762 - 83,355,362 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000113291   ⟹   ENSRNOP00000082692
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1183,280,762 - 83,355,362 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000117596   ⟹   ENSRNOP00000085424
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1183,280,762 - 83,355,362 (+)Ensembl
RefSeq Acc Id: NM_001108325   ⟹   NP_001101795
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,280,854 - 83,355,353 (+)NCBI
Rnor_6.01187,553,868 - 87,628,502 (-)NCBI
Rnor_5.01190,606,469 - 90,681,242 (-)NCBI
RGSC_v3.41185,270,503 - 85,344,999 (+)RGD
Celera1182,052,699 - 82,127,011 (+)RGD
Sequence:
RefSeq Acc Id: XM_006248702   ⟹   XP_006248764
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,280,731 - 83,354,847 (+)NCBI
Rnor_6.01187,554,608 - 87,628,630 (-)NCBI
Rnor_5.01190,606,469 - 90,681,242 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006248706   ⟹   XP_006248768
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,280,722 - 83,354,410 (+)NCBI
Rnor_6.01187,554,811 - 87,628,631 (-)NCBI
Rnor_5.01190,606,469 - 90,681,242 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039088529   ⟹   XP_038944457
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,280,731 - 83,354,847 (+)NCBI
RefSeq Acc Id: XM_039088530   ⟹   XP_038944458
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,280,723 - 83,354,847 (+)NCBI
RefSeq Acc Id: XM_039088531   ⟹   XP_038944459
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,280,731 - 83,354,847 (+)NCBI
RefSeq Acc Id: XM_039088532   ⟹   XP_038944460
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,280,723 - 83,354,847 (+)NCBI
RefSeq Acc Id: XM_039088533   ⟹   XP_038944461
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,280,723 - 83,354,847 (+)NCBI
RefSeq Acc Id: XR_005491046
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,280,731 - 83,356,006 (+)NCBI
RefSeq Acc Id: XR_005491047
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,280,731 - 83,356,006 (+)NCBI
RefSeq Acc Id: XR_005491048
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,280,731 - 83,353,156 (+)NCBI
RefSeq Acc Id: XR_005491049
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,280,731 - 83,355,374 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001101795   ⟸   NM_001108325
- UniProtKB: G3V684 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248764   ⟸   XM_006248702
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006248768   ⟸   XM_006248706
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: ENSRNOP00000002568   ⟸   ENSRNOT00000002568
RefSeq Acc Id: XP_038944458   ⟸   XM_039088530
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038944460   ⟸   XM_039088532
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038944461   ⟸   XM_039088533
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038944457   ⟸   XM_039088529
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038944459   ⟸   XM_039088531
- Peptide Label: isoform X4
RefSeq Acc Id: ENSRNOP00000085424   ⟸   ENSRNOT00000117596
RefSeq Acc Id: ENSRNOP00000091727   ⟸   ENSRNOT00000098103
RefSeq Acc Id: ENSRNOP00000082692   ⟸   ENSRNOT00000113291

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V684-F1-model_v2 AlphaFold G3V684 1-790 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698323
Promoter ID:EPDNEW_R8848
Type:initiation region
Name:Med15_1
Description:mediator complex subunit 15
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01187,628,588 - 87,628,648EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
11 87590970 87590971 C T snv ACI/N (MCW), WN/N (MCW), WKY/N (MCW), MR/N (MCW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307560 AgrOrtholog
BioCyc Gene G2FUF-20609 BioCyc
Ensembl Genes ENSRNOG00000001877 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000002568 ENTREZGENE
  ENSRNOP00000002568.4 UniProtKB/TrEMBL
  ENSRNOP00000082692.1 UniProtKB/TrEMBL
  ENSRNOP00000085424 ENTREZGENE
  ENSRNOP00000085424.1 UniProtKB/TrEMBL
  ENSRNOP00000091727.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002568 ENTREZGENE
  ENSRNOT00000002568.6 UniProtKB/TrEMBL
  ENSRNOT00000098103.1 UniProtKB/TrEMBL
  ENSRNOT00000113291.1 UniProtKB/TrEMBL
  ENSRNOT00000117596 ENTREZGENE
  ENSRNOT00000117596.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.246.20 UniProtKB/TrEMBL
InterPro KIX_dom_sf UniProtKB/TrEMBL
  Mediator_Med15_met UniProtKB/TrEMBL
KEGG Report rno:360743 UniProtKB/TrEMBL
NCBI Gene 360743 ENTREZGENE
Pfam Med15 UniProtKB/TrEMBL
PhenoGen Med15 PhenoGen
UniProt A0A8I5ZVE0_RAT UniProtKB/TrEMBL
  A0A8I6A373_RAT UniProtKB/TrEMBL
  A0A8I6GJV4_RAT UniProtKB/TrEMBL
  B2RZ40_RAT UniProtKB/TrEMBL
  G3V684 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Med15  mediator complex subunit 15  Pcqap_predicted  positive cofactor 2, multiprotein complex, glutamine/Q-rich-associated protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Pcqap_predicted  positive cofactor 2, multiprotein complex, glutamine/Q-rich-associated protein (predicted)      Symbol and Name status set to approved 70820 APPROVED