Klhl6 (kelch-like family member 6) - Rat Genome Database

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Gene: Klhl6 (kelch-like family member 6) Rattus norvegicus
Analyze
Symbol: Klhl6
Name: kelch-like family member 6
RGD ID: 1307521
Description: Predicted to be involved in B cell receptor signaling pathway and germinal center formation. Predicted to act upstream of or within response to bacterium. Orthologous to human KLHL6 (kelch like family member 6); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: kelch-like 6; kelch-like 6 (Drosophila); kelch-like protein 6; LOC287974
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21180,970,917 - 81,010,593 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1180,970,917 - 81,009,677 (+)Ensembl
Rnor_6.01184,745,958 - 84,785,315 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1184,745,904 - 84,785,893 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01187,808,385 - 87,847,742 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41183,221,776 - 83,260,528 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11183,279,726 - 83,318,448 (+)NCBI
Celera1179,806,183 - 79,844,910 (+)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

Additional References at PubMed
PMID:16166635   PMID:21873635   PMID:23012479  


Genomics

Comparative Map Data
Klhl6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21180,970,917 - 81,010,593 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1180,970,917 - 81,009,677 (+)Ensembl
Rnor_6.01184,745,958 - 84,785,315 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1184,745,904 - 84,785,893 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01187,808,385 - 87,847,742 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41183,221,776 - 83,260,528 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11183,279,726 - 83,318,448 (+)NCBI
Celera1179,806,183 - 79,844,910 (+)NCBICelera
Cytogenetic Map11q23NCBI
KLHL6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383183,487,551 - 183,555,706 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3183,487,551 - 183,555,706 (-)EnsemblGRCh38hg38GRCh38
GRCh373183,205,339 - 183,273,494 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363184,688,013 - 184,756,193 (-)NCBINCBI36hg18NCBI36
Build 343184,688,040 - 184,756,110NCBI
Celera3181,641,698 - 181,709,843 (-)NCBI
Cytogenetic Map3q27.1NCBI
HuRef3180,611,770 - 180,679,998 (-)NCBIHuRef
CHM1_13183,168,972 - 183,237,150 (-)NCBICHM1_1
Klhl6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391619,765,242 - 19,801,832 (-)NCBIGRCm39mm39
GRCm39 Ensembl1619,765,246 - 19,801,787 (-)Ensembl
GRCm381619,946,492 - 19,983,049 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1619,946,496 - 19,983,037 (-)EnsemblGRCm38mm10GRCm38
MGSCv371619,946,586 - 19,983,122 (-)NCBIGRCm37mm9NCBIm37
MGSCv361619,860,060 - 19,896,520 (-)NCBImm8
Celera1620,509,929 - 20,546,858 (-)NCBICelera
Cytogenetic Map16A3NCBI
Klhl6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542023,813,482 - 23,877,886 (+)NCBIChiLan1.0ChiLan1.0
KLHL6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13188,692,193 - 188,760,244 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3188,692,200 - 188,760,926 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03180,523,141 - 180,591,218 (-)NCBIMhudiblu_PPA_v0panPan3
KLHL6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13416,443,282 - 16,556,991 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3416,446,944 - 16,504,549 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3420,531,581 - 20,645,243 (-)NCBI
ROS_Cfam_1.03416,351,275 - 16,464,989 (-)NCBI
ROS_Cfam_1.0 Ensembl3416,351,275 - 16,472,437 (-)Ensembl
UMICH_Zoey_3.13416,390,376 - 16,503,817 (-)NCBI
UNSW_CanFamBas_1.03416,376,664 - 16,438,114 (-)NCBI
UU_Cfam_GSD_1.03416,614,814 - 16,728,495 (-)NCBI
Klhl6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602120,134,597 - 120,194,353 (+)NCBI
SpeTri2.0NW_0049365786,226,533 - 6,284,343 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.113121,426,618 - 121,487,260 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213130,829,174 - 130,850,400 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1155,844,728 - 5,912,392 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl155,845,721 - 5,913,734 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606314,630,818 - 14,705,887 (+)NCBIVero_WHO_p1.0
Klhl6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473072,916,601 - 72,972,204 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D11Rat91  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21180,970,337 - 80,970,606 (+)MAPPERmRatBN7.2
Rnor_6.01184,745,379 - 84,745,647NCBIRnor6.0
Rnor_5.01187,807,806 - 87,808,074UniSTSRnor5.0
RGSC_v3.41183,221,197 - 83,221,465UniSTSRGSC3.4
RGSC_v3.41183,221,196 - 83,221,465RGDRGSC3.4
RGSC_v3.11183,279,117 - 83,279,386RGD
Celera1179,805,604 - 79,805,872UniSTS
RH 2.0 Map21118.1RGD
SHRSP x BN Map1136.5499RGD
Cytogenetic Map11q23UniSTS
D11Got80  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21180,975,229 - 80,975,431 (+)MAPPERmRatBN7.2
Rnor_6.01184,750,267 - 84,750,468NCBIRnor6.0
Rnor_5.01187,812,694 - 87,812,895UniSTSRnor5.0
RGSC_v3.41183,226,084 - 83,226,286RGDRGSC3.4
RGSC_v3.41183,226,085 - 83,226,286UniSTSRGSC3.4
RGSC_v3.11183,284,005 - 83,284,207RGD
Celera1179,810,492 - 79,810,693UniSTS
RH 3.4 Map11678.4RGD
RH 3.4 Map11678.4UniSTS
Cytogenetic Map11q23UniSTS
RH129598  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21181,010,061 - 81,010,226 (+)MAPPERmRatBN7.2
Rnor_6.01184,785,115 - 84,785,279NCBIRnor6.0
Rnor_5.01187,847,542 - 87,847,706UniSTSRnor5.0
RGSC_v3.41183,260,913 - 83,261,077UniSTSRGSC3.4
Celera1179,845,295 - 79,845,459UniSTS
RH 3.4 Map11689.1UniSTS
Cytogenetic Map11q23UniSTS
Ewsr1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21180,994,724 - 80,995,517 (+)MAPPERmRatBN7.2
Rnor_6.01184,769,778 - 84,770,570NCBIRnor6.0
Rnor_5.01187,832,205 - 87,832,997UniSTSRnor5.0
RGSC_v3.41183,245,576 - 83,246,368UniSTSRGSC3.4
RGSC_v3.4424,171,846 - 24,172,741UniSTSRGSC3.4
Celera1179,829,968 - 79,830,760UniSTS
Celera422,991,908 - 22,992,803UniSTS
Cytogenetic Map4q12UniSTS
Cytogenetic Map11q23UniSTS
Cytogenetic Map14q21UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116944607082846715Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)117695713183051965Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:73
Count of miRNA genes:59
Interacting mature miRNAs:70
Transcripts:ENSRNOT00000002617
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 8 19 2 1
Low 1 43 48 40 40 6 6 74 35 37 10 6
Below cutoff 1 1 1 2 4 2 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000002617   ⟹   ENSRNOP00000002617
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1180,970,917 - 81,009,677 (+)Ensembl
Rnor_6.0 Ensembl1184,745,904 - 84,785,893 (+)Ensembl
RefSeq Acc Id: NM_001105867   ⟹   NP_001099337
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21180,970,917 - 81,009,677 (+)NCBI
Rnor_6.01184,745,958 - 84,784,730 (+)NCBI
Rnor_5.01187,808,385 - 87,847,742 (+)NCBI
RGSC_v3.41183,221,776 - 83,260,528 (+)RGD
Celera1179,806,183 - 79,844,910 (+)RGD
Sequence:
RefSeq Acc Id: XM_006248594   ⟹   XP_006248656
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21180,970,942 - 81,010,593 (+)NCBI
Rnor_6.01184,746,032 - 84,785,315 (+)NCBI
Rnor_5.01187,808,385 - 87,847,742 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039088086   ⟹   XP_038944014
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21180,970,943 - 81,010,593 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001099337 (Get FASTA)   NCBI Sequence Viewer  
  XP_006248656 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944014 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL77984 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001099337   ⟸   NM_001105867
- UniProtKB: D4A1Z1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248656   ⟸   XM_006248594
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000002617   ⟸   ENSRNOT00000002617
RefSeq Acc Id: XP_038944014   ⟸   XM_039088086
- Peptide Label: isoform X2
Protein Domains
BTB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A1Z1-F1-model_v2 AlphaFold D4A1Z1 1-619 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698285
Promoter ID:EPDNEW_R8810
Type:initiation region
Name:Klhl6_1
Description:kelch-like family member 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01184,745,975 - 84,746,035EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307521 AgrOrtholog
BioCyc Gene G2FUF-20709 BioCyc
Ensembl Genes ENSRNOG00000001908 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000002617 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002617 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.120.10.80 UniProtKB/TrEMBL
  3.30.710.10 UniProtKB/TrEMBL
InterPro BACK UniProtKB/TrEMBL
  BTB/POZ-like UniProtKB/TrEMBL
  BTB/POZ_fold UniProtKB/TrEMBL
  Kelch-like_gigaxonin UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  KLHL6 UniProtKB/TrEMBL
KEGG Report rno:287974 UniProtKB/TrEMBL
NCBI Gene 287974 ENTREZGENE
PANTHER PTHR24412:SF428 UniProtKB/TrEMBL
Pfam BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
PhenoGen Klhl6 PhenoGen
PIRSF Kelch-like_protein_gigaxonin UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
SMART BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch UniProtKB/TrEMBL
Superfamily-SCOP BTB/POZ_fold UniProtKB/TrEMBL
  SSF117281 UniProtKB/TrEMBL
UniProt D4A1Z1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-06 Klhl6  kelch-like family member 6  Klhl6  kelch-like 6 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Klhl6  kelch-like 6 (Drosophila)   Klhl6_predicted  kelch-like 6 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Klhl6_predicted  kelch-like 6 (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED