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Gene: Set (SET nuclear proto-oncogene) Rattus norvegicus
Symbol: Set
Name: SET nuclear proto-oncogene
Description: Predicted to have DNA binding activity. Predicted to be involved in negative regulation of neuron apoptotic process and negative regulation of transcription, DNA-templated. Predicted to localize to several cellular components, including the endoplasmic reticulum; lipid droplet; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Orthologous to human SET (SET nuclear proto-oncogene); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ab1-115; I-2PP2A; liver regeneration-related protein LRRGR00002; LOC307947; phosphatase 2A inhibitor I2PP2A; SET nuclear oncogene; SET translocation; TAF-I; template-activating factor I
Homo sapiens (human) : SET (SET nuclear proto-oncogene)  HGNC  Alliance
Mus musculus (house mouse) : Set (SET nuclear oncogene)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Set (SET nuclear proto-oncogene)
Pan paniscus (bonobo/pygmy chimpanzee) : SET (SET nuclear proto-oncogene)
Canis lupus familiaris (dog) : SET (SET nuclear proto-oncogene)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Set (SET nuclear proto-oncogene)
Sus scrofa (pig) : SET (SET nuclear proto-oncogene)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01958,420,635 - 58,422,153 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1958,419,961 - 58,421,504 (+)Ensembl
Rnor_5.01969,119,722 - 69,121,240 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41955,797,060 - 55,798,578 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11955,801,940 - 55,803,459 (+)NCBI
Celera1952,922,285 - 52,923,803 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Set
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307467
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.