Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Tysnd1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TYSND1 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | multiple interactions | ISO | Tysnd1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TYSND1 mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TYSND1 mRNA | CTD | PMID:21215274 and PMID:32109520 | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Tysnd1 (Mus musculus) | 6480464 | [bisphenol S co-treated with Tretinoin] results in decreased expression of TYSND1 mRNA | CTD | PMID:30951980 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of TYSND1 mRNA | CTD | PMID:30047161 | all-trans-retinoic acid | multiple interactions | ISO | Tysnd1 (Mus musculus) | 6480464 | [bisphenol S co-treated with Tretinoin] results in decreased expression of TYSND1 mRNA | CTD | PMID:30951980 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of TYSND1 mRNA | CTD | PMID:30047161 | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of TYSND1 mRNA | CTD | PMID:30779732 | aristolochic acid A | decreases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of TYSND1 mRNA and aristolochic acid I results in decreased expression of TYSND1 protein | CTD | PMID:33212167 | arsane | affects methylation | ISO | TYSND1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of TYSND1 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | TYSND1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of TYSND1 gene | CTD | PMID:25304211 | arsenite(3-) | multiple interactions | ISO | TYSND1 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to TYSND1 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | increases mutagenesis | ISO | TYSND1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of TYSND1 gene | CTD | PMID:25435355 | benzo[a]pyrene | increases methylation | ISO | TYSND1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TYSND1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | Tysnd1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of TYSND1 mRNA | CTD | PMID:27195522 | bisphenol A | increases expression | ISO | Tysnd1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of TYSND1 mRNA | CTD | PMID:32156529 | butan-1-ol | multiple interactions | ISO | TYSND1 (Homo sapiens) | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of TYSND1 mRNA | CTD | PMID:29432896 | butanal | decreases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of TYSND1 mRNA | CTD | PMID:26079696 | cadmium dichloride | decreases expression | ISO | Tysnd1 (Mus musculus) | 6480464 | Cadmium Chloride results in decreased expression of TYSND1 mRNA | CTD | PMID:20883709 | chlorpyrifos | increases expression | ISO | Tysnd1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of TYSND1 mRNA | CTD | PMID:37019170 | cisplatin | multiple interactions | ISO | TYSND1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of TYSND1 mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | Tysnd1 (Mus musculus) | 6480464 | [SLC22A1 protein affects the susceptibility to Cisplatin] which affects the expression of TYSND1 protein | CTD | PMID:31493026 | cisplatin | increases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of TYSND1 mRNA | CTD | PMID:27392435 | clofibrate | multiple interactions | ISO | Tysnd1 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of TYSND1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of TYSND1 mRNA] | CTD | PMID:17585979 | clofibric acid | affects expression | EXP | | 6480464 | Clofibric Acid affects the expression of TYSND1 mRNA | CTD | PMID:17602206 | copper atom | multiple interactions | ISO | TYSND1 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of TYSND1 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | TYSND1 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of TYSND1 mRNA | CTD | PMID:20971185 | copper(II) sulfate | decreases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of TYSND1 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TYSND1 mRNA | CTD | PMID:25562108 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of TYSND1 mRNA | CTD | PMID:21266533 | dorsomorphin | multiple interactions | ISO | TYSND1 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TYSND1 mRNA | CTD | PMID:29803840 | folic acid | multiple interactions | ISO | Tysnd1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TYSND1 mRNA | CTD | PMID:22206623 | FR900359 | increases phosphorylation | ISO | TYSND1 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of TYSND1 protein | CTD | PMID:37730182 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of TYSND1 mRNA | CTD | PMID:33387578 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of TYSND1 mRNA | CTD | PMID:24136188 | inulin | multiple interactions | ISO | Tysnd1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of TYSND1 mRNA | CTD | PMID:36331819 | iron dichloride | decreases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | ferrous chloride results in decreased expression of TYSND1 mRNA | CTD | PMID:35984750 | ivermectin | decreases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of TYSND1 protein | CTD | PMID:32959892 | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of TYSND1 mRNA | CTD | PMID:24136188 | mercury dibromide | decreases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | mercuric bromide results in decreased expression of TYSND1 mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | ISO | TYSND1 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TYSND1 mRNA | CTD | PMID:27188386 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of TYSND1 mRNA | CTD | PMID:30467583 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of TYSND1 mRNA | CTD | PMID:30047161 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of TYSND1 mRNA | CTD | PMID:24136188 | nickel atom | decreases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | Nickel results in decreased expression of TYSND1 mRNA | CTD | PMID:24768652 and PMID:25583101 | paracetamol | affects expression | ISO | Tysnd1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TYSND1 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TYSND1 mRNA | CTD | PMID:33387578 | paracetamol | multiple interactions | ISO | Tysnd1 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of TYSND1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of TYSND1 mRNA] | CTD | PMID:17585979 | perfluorononanoic acid | decreases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of TYSND1 mRNA | CTD | PMID:25812627 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tysnd1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TYSND1 mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of TYSND1 mRNA | CTD | PMID:36331819 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of TYSND1 mRNA | CTD | PMID:25812627 | perfluorooctanoic acid | decreases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of TYSND1 mRNA | CTD | PMID:25812627 | phenylmercury acetate | decreases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of TYSND1 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | TYSND1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TYSND1 mRNA | CTD | PMID:27188386 | pirinixic acid | increases expression | ISO | Tysnd1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of TYSND1 mRNA | CTD | PMID:17426115 more ... | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of TYSND1 mRNA | CTD | PMID:30047161 | SB 431542 | multiple interactions | ISO | TYSND1 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | decreases expression | ISO | Tysnd1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of TYSND1 mRNA | CTD | PMID:20883709 | sodium arsenite | increases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of TYSND1 mRNA | CTD | PMID:34032870 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of TYSND1 mRNA | CTD | PMID:30047161 | sunitinib | decreases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of TYSND1 mRNA | CTD | PMID:31533062 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of TYSND1 mRNA | CTD | PMID:34492290 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of TYSND1 gene | CTD | PMID:27618143 | triptonide | increases expression | ISO | Tysnd1 (Mus musculus) | 6480464 | triptonide results in increased expression of TYSND1 mRNA | CTD | PMID:33045310 | valproic acid | affects expression | ISO | TYSND1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TYSND1 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | TYSND1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of TYSND1 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | TYSND1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TYSND1 mRNA | CTD | PMID:27188386 | |