Tm2d2 (TM2 domain containing 2) - Rat Genome Database

Name: Tm2d2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Tm2d2 (TM2 domain containing 2) Rattus norvegicus

Analyze

Symbol:

Tm2d2

Name:

TM2 domain containing 2

RGD ID:

1306769

Description:

Predicted to be located in membrane. Orthologous to human TM2D2 (TM2 domain containing 2); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

2410018g23rik; BBP-like protein 1; LOC290833; RGD1306769; similar to RIKEN cDNA 2410018G23; TM2 domain-containing protein 2

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TM2D2 (TM2 domain containing 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Tm2d2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tm2d2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TM2D2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TM2D2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tm2d2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TM2D2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TM2D2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tm2d2 (TM2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Tm2d2 (TM2 domain containing 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TM2D2 (TM2 domain containing 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tm2d2 (TM2 domain containing 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG11103	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	C02F5.13	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Candidate Gene For:

Arunc2 Arunc1 Arunc4

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	16	67,016,683 - 67,022,206 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	67,012,675 - 67,022,226 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	72,293,869 - 72,299,391 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	16	75,699,837 - 75,705,359 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	16	70,946,366 - 70,951,899 (-)	NCBI	Rnor_WKY
Rnor_6.0	16	71,804,368 - 71,809,891 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	71,804,350 - 71,809,925 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	71,453,135 - 71,458,658 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	71,440,489 - 71,446,012 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	71,440,754 - 71,446,277 (-)	NCBI
Celera	16	64,921,244 - 64,926,766 (-)	NCBI		Celera
Cytogenetic Map	16	q12.4	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hypogonadotropic hypogonadism 2 with or without anosmia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

amphetamine (EXP)

antimycin A (ISO)

aristolochic acid A (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bortezomib (ISO)

buspirone (EXP)

chrysene (ISO)

cisplatin (ISO)

clobetasol (ISO)

clofibrate (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

deguelin (ISO)

dicrotophos (ISO)

epoxiconazole (ISO)

fenthion (ISO)

finasteride (EXP)

flutamide (EXP)

folic acid (ISO)

nimesulide (EXP)

paracetamol (EXP,ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

potassium dichromate (ISO)

sunitinib (ISO)

testosterone (EXP)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

trichloroethene (EXP)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

Cellular Component

cellular_component (ND)

membrane (IEA)

Molecular Function

molecular_function (ND)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Tm2d2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	16	67,016,683 - 67,022,206 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	67,012,675 - 67,022,226 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	72,293,869 - 72,299,391 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	16	75,699,837 - 75,705,359 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	16	70,946,366 - 70,951,899 (-)	NCBI	Rnor_WKY
Rnor_6.0	16	71,804,368 - 71,809,891 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	71,804,350 - 71,809,925 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	71,453,135 - 71,458,658 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	71,440,489 - 71,446,012 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	71,440,754 - 71,446,277 (-)	NCBI
Celera	16	64,921,244 - 64,926,766 (-)	NCBI		Celera
Cytogenetic Map	16	q12.4	NCBI

TM2D2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	38,988,808 - 38,996,990 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	8	38,988,808 - 38,996,824 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	38,846,327 - 38,854,028 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	38,965,484 - 38,973,198 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	8	37,797,825 - 37,805,586 (-)	NCBI		Celera
Cytogenetic Map	8	p11.22	NCBI
HuRef	8	37,379,168 - 37,386,883 (-)	NCBI		HuRef
CHM1_1	8	39,048,404 - 39,056,118 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	39,265,950 - 39,273,651 (-)	NCBI		T2T-CHM13v2.0

Tm2d2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	25,507,227 - 25,513,276 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	25,507,227 - 25,513,276 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	25,017,211 - 25,023,260 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	25,017,211 - 25,023,260 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	26,127,683 - 26,133,732 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	26,482,825 - 26,488,804 (+)	NCBI		MGSCv36	mm8
Celera	8	26,484,819 - 26,490,229 (+)	NCBI		Celera
Cytogenetic Map	8	A2	NCBI

Tm2d2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955463	14,537,919 - 14,545,823 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955463	14,537,902 - 14,545,147 (-)	NCBI	ChiLan1.0	ChiLan1.0

TM2D2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	8	35,466,949 - 35,472,985 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	35,466,949 - 35,472,985 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	8	38,290,204 - 38,297,903 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

TM2D2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	26,551,563 - 26,557,554 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	26,551,628 - 26,556,285 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	27,073,125 - 27,079,548 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	28,383,184 - 28,389,618 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	28,383,188 - 28,389,614 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	26,676,903 - 26,683,328 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	27,253,614 - 27,260,037 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	27,291,910 - 27,298,338 (+)	NCBI		UU_Cfam_GSD_1.0

Tm2d2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	49,159,956 - 49,163,023 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936710	2,297,247 - 2,301,232 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936710	2,298,233 - 2,301,239 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TM2D2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	47,601,616 - 47,611,804 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	47,601,940 - 47,611,802 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	54,674,879 - 54,684,745 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TM2D2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	37,011,616 - 37,017,621 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	37,009,511 - 37,017,474 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	4,962,725 - 4,969,314 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tm2d2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624780	4,612,124 - 4,618,211 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624780	4,612,830 - 4,618,444 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tm2d2
90 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	419
Count of miRNA genes:	214
Interacting mature miRNAs:	261
Transcripts:	ENSRNOT00000022425
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	380245	80345693	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor depth of invasion (CMO:0001888)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor depth of invasion (CMO:0001888)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17696791	82635055	Rat
70215	Niddm29	Non-insulin dependent diabetes mellitus QTL 29	3.54		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	16	19004435	75226532	Rat
8694453	Bw172	Body weight QTL 172	8.33	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	16	24325513	69325513	Rat
6903294	Stl30	Serum triglyceride level QTL 30	2.6	0.0013	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	16	25152793	70152793	Rat
1578768	Stresp22	Stress response QTL 22	2.8		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	16	35288870	80288870	Rat
2293690	Bss45	Bone structure and strength QTL 45	5.13	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	16	37752156	82752156	Rat
2300163	Bmd64	Bone mineral density QTL 64	5.3	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	16	37752156	82752156	Rat
7205510	Activ5	Activity QTL 5	3.78	0.00028	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	42396345	84729064	Rat
8694429	Bw164	Body weight QTL 164	5	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	16	52726464	84729064	Rat
8694364	Abfw7	Abdominal fat weight QTL 7	12.22	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	16	52726464	84729064	Rat
7411648	Foco22	Food consumption QTL 22	15	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	52726464	84729064	Rat
631525	Pia14	Pristane induced arthritis QTL 14	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	16	55711087	83402471	Rat

Markers in Region

RH127392

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	67,016,882 - 67,017,063 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	71,804,568 - 71,804,748	NCBI	Rnor6.0
Rnor_5.0	16	71,453,335 - 71,453,515	UniSTS	Rnor5.0
RGSC_v3.4	16	71,440,689 - 71,440,869	UniSTS	RGSC3.4
Celera	16	64,921,444 - 64,921,624	UniSTS
RH 3.4 Map	16	633.1	UniSTS
Cytogenetic Map	16	q12.4	UniSTS

RH136732

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	67,022,996 - 67,023,132 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	71,810,682 - 71,810,817	NCBI	Rnor6.0
Rnor_5.0	16	71,459,449 - 71,459,584	UniSTS	Rnor5.0
RGSC_v3.4	16	71,446,803 - 71,446,938	UniSTS	RGSC3.4
Celera	16	64,927,557 - 64,927,692	UniSTS
RH 3.4 Map	16	624.5	UniSTS
Cytogenetic Map	16	q12.4	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	74	35	41	11	8
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001017444	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC093382	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000283	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000022425 ⟹ ENSRNOP00000022425

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	67,016,683 - 67,022,226 (-)	Ensembl
Rnor_6.0 Ensembl	16	71,804,350 - 71,809,925 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000112655 ⟹ ENSRNOP00000094884

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	67,012,675 - 67,022,184 (-)	Ensembl

RefSeq Acc Id:

NM_001017444 ⟹ NP_001017444

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	16	67,016,683 - 67,022,206 (-)	NCBI
Rnor_6.0	16	71,804,368 - 71,809,891 (-)	NCBI
Rnor_5.0	16	71,453,135 - 71,458,658 (-)	NCBI
RGSC_v3.4	16	71,440,489 - 71,446,012 (-)	RGD
Celera	16	64,921,244 - 64,926,766 (-)	RGD

Sequence:

show sequence

CAGCGCCCGGCTTGGGTCGGCCGTGGCGGCCTGGCTGTTTTTAGGCCAGGTCTCTAGGACCGGC
CCGGAAGATGGTGCTGGGCGGTTGCCCTGTGAGTTACCTATTGCTATGCGGCCAGGCGGCCTTG
CTTTTGGGGAACCTGCTGCTGCTGCACTGTGTCTCTCGGAGCCACTCGTTTAATGCTACGGCCG
AACTGGATCTCACCCCCTCAGGCGCCGCTCACCTCGAGGGTCCCGCGGCCTCGAGCTGGGAATA
CAGTGACCCCAACTCTCCAGTCATCCTTTGCTCTTACCTACCCGACGAGTTTGTAGATTGCGAT
GCCCCAGTGGATCACGTTGGAAATGCAACTGCATACCAGGAACTTGGTTATGGTTGTCTCAAGT
TTGGGGGTCAGGCCTACAGTGATGTGGAACACACTGCAGTCCAGTGCAGAGCCCTGGAGGGAAT
CGAGTGTGCCAGCCCCAGGACCTTCCTACGAAAAAATAAGCCTTGTATAAAGTACACTGGACAC
TACTTCATAACCACGCTTCTCTACTCCTTCTTCCTGGGATGCTTCGGAGTCGACCGCTTCTGTC
TGGGACACACTGGAACAGCGGTTGGGAAGCTGCTAACCCTTGGAGGACTGGGGATCTGGTGGTT
CGTCGATCTTATTTTGCTCATCACTGGGGGGCTGATGCCTAGTGACGGCAGCAACTGGTGTACT
GTCTACTAAACGTGGCTGCTGCCCTCTGCCGGCAACTGGTGTACTGTCTACTAAGCACGGCTGC
TGTCCTCTGCCGGCCAGGGAAGCGAGCATTTGGCTGGCGGGATAATTAGGAGAAGCTCTGAATT
CTCTGAACATCACCGTCCTCTTTAGGAGGAAGGACCGACCGAGTTTTTCAACCCAAATCTTAAC
CTTGCAGACCAGAATGACAAGCAGTATTGTGGGAGCCCAGTCATACCTTGCCTCACATACAAAA
GCTCAAAGCTCAAAGACAGTGACTTTTATCCAGAGATCATTTTCAGTGATGTTTCTGTGTGGCT
GGATTTCAGTCGTTTGGAGCAGGGGGACCCAGTAGGATAAACCGAGGGAATGTTTAACCACTCA
CAGCCTTTTGTGACCCTCAGTTTTCATGCACAGATGAGAAGCTGCGCCAGGGAGAAGTCTTGAG
AATATAGAAATGACTGGATTTTAATACACACCAAAAGTCTGACTCTGGGAATTTAAATTGCAAA
ATAAAGTTTTAAAACCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001017444	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH93382	(Get FASTA)	NCBI Sequence Viewer
	EDM09045	(Get FASTA)	NCBI Sequence Viewer
	EDM09046	(Get FASTA)	NCBI Sequence Viewer
	Q566R2	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001017444 ⟸ NM_001017444
- Peptide Label:	precursor
- UniProtKB:	Q566R2 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MVLGGCPVSYLLLCGQAALLLGNLLLLHCVSRSHSFNATAELDLTPSGAAHLEGPAASSWEYSD PNSPVILCSYLPDEFVDCDAPVDHVGNATAYQELGYGCLKFGGQAYSDVEHTAVQCRALEGIEC ASPRTFLRKNKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVD LILLITGGLMPSDGSNWCTVY hide sequence

RefSeq Acc Id:

ENSRNOP00000022425 ⟸ ENSRNOT00000022425

RefSeq Acc Id:

ENSRNOP00000094884 ⟸ ENSRNOT00000112655

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q566R2-F1-model_v2	AlphaFold	Q566R2	1-213	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700173

Promoter ID:

EPDNEW_R10697

Type:

multiple initiation site

Name:

Tm2d2_1

Description:

TM2 domain containing 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	71,809,890 - 71,809,950	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306769	AgrOrtholog
BioCyc Gene	G2FUF-10952	BioCyc
Ensembl Genes	ENSRNOG00000016559	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000022425.5	UniProtKB/TrEMBL
	ENSRNOP00000094884	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000022425.7	UniProtKB/TrEMBL
	ENSRNOT00000112655	ENTREZGENE, UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7389050	IMAGE-MGC_LOAD
InterPro	TM2	UniProtKB/Swiss-Prot
KEGG Report	rno:290833	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:112677	IMAGE-MGC_LOAD
NCBI Gene	290833	ENTREZGENE
Pfam	TM2	UniProtKB/Swiss-Prot
PhenoGen	Tm2d2	PhenoGen
UniProt	A0A8L2QCW5_RAT	UniProtKB/TrEMBL
	Q566R2	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Tm2d2	TM2 domain containing 2	RGD1306769	similar to RIKEN cDNA 2410018G23	Symbol and Name updated	1299863	APPROVED
2005-12-06	RGD1306769	similar to RIKEN cDNA 2410018G23	RGD1306769_predicted	similar to RIKEN cDNA 2410018G23 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1306769_predicted	similar to RIKEN cDNA 2410018G23 (predicted)	LOC290833_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC290833_predicted	similar to RIKEN cDNA 2410018G23 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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