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Gene: Prodh2 (proline dehydrogenase 2) Rattus norvegicus
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Symbol: Prodh2
Name: proline dehydrogenase 2
Description: Predicted to have FAD binding activity and proline dehydrogenase activity. Predicted to be involved in proline catabolic process to glutamate. Predicted to localize to the mitochondrion. Orthologous to human PRODH2 (proline dehydrogenase 2); PARTICIPATES IN arginine and proline metabolic pathway; INTERACTS WITH (+)-schisandrin B; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: hydroxyproline dehydrogenase; HYPDH; LOC361538; probable proline dehydrogenase 2; probable proline oxidase 2; proline dehydrogenase (oxidase) 2; proline oxidase-like protein
Orthologs:
Homo sapiens (human) : PRODH2 (proline dehydrogenase 2)  HGNC  Alliance
Mus musculus (house mouse) : Prodh2 (proline dehydrogenase (oxidase) 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prodh2 (proline dehydrogenase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PRODH2 (proline dehydrogenase 2)
Canis lupus familiaris (dog) : PRODH2 (proline dehydrogenase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prodh2 (proline dehydrogenase 2)
Sus scrofa (pig) : PRODH2 (proline dehydrogenase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0188,955,125 - 88,968,501 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0190,110,667 - 90,123,506 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,546,014 - 85,559,530 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1185,624,134 - 85,637,586 (+)NCBI
Celera180,125,644 - 80,138,959 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Prodh2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306761
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.