Klhl22 (kelch-like family member 22) - Rat Genome Database

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Gene: Klhl22 (kelch-like family member 22) Rattus norvegicus
Analyze
Symbol: Klhl22
Name: kelch-like family member 22
RGD ID: 1306288
Description: Predicted to enable 14-3-3 protein binding activity and ubiquitin ligase-substrate adaptor activity. Predicted to be involved in several processes, including cellular response to leucine; mitotic spindle assembly checkpoint signaling; and positive regulation of TORC1 signaling. Predicted to be located in several cellular components, including centrosome; intercellular bridge; and intracellular membrane-bounded organelle. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytosol; mitotic spindle; and polar microtubule. Predicted to colocalize with lysosome and nucleus. Orthologous to human KLHL22 (kelch like family member 22); INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: kelch-like 22; kelch-like 22 (Drosophila); kelch-like protein 22; LOC303792; RGD1306288; similar to hypothetical protein FLJ14360
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21183,190,891 - 83,231,746 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,190,891 - 83,231,770 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1191,919,784 - 91,960,680 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01184,580,927 - 84,621,830 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01183,634,547 - 83,675,443 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01187,646,489 - 87,718,808 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,677,966 - 87,718,826 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01190,699,112 - 90,771,253 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,179,262 - 85,220,103 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11185,219,855 - 85,260,693 (-)NCBI
Celera1181,962,736 - 82,003,585 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centrosome  (IEA,ISO,ISS)
Cul3-RING ubiquitin ligase complex  (IBA,IEA,ISO,ISS)
cytoplasm  (ISO,ISS)
cytosol  (IBA,IEA,ISO,ISS)
intercellular bridge  (ISO)
intracellular membrane-bounded organelle  (ISO)
lysosome  (IEA,ISO,ISS)
microtubule cytoskeleton  (ISO)
mitotic spindle  (IBA,IEA,ISO,ISS)
nucleus  (IBA,IEA,ISO,ISS)
polar microtubule  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19995937   PMID:23455478   PMID:29769719   PMID:33450132  


Genomics

Comparative Map Data
Klhl22
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21183,190,891 - 83,231,746 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,190,891 - 83,231,770 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1191,919,784 - 91,960,680 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01184,580,927 - 84,621,830 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01183,634,547 - 83,675,443 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01187,646,489 - 87,718,808 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,677,966 - 87,718,826 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01190,699,112 - 90,771,253 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,179,262 - 85,220,103 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11185,219,855 - 85,260,693 (-)NCBI
Celera1181,962,736 - 82,003,585 (-)NCBICelera
Cytogenetic Map11q23NCBI
KLHL22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382220,441,519 - 20,495,795 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2220,441,519 - 20,495,844 (-)EnsemblGRCh38hg38GRCh38
GRCh372220,795,806 - 20,850,082 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362219,125,806 - 19,180,122 (-)NCBINCBI36Build 36hg18NCBI36
Celera224,282,529 - 4,336,886 (-)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef224,059,895 - 4,107,538 (-)NCBIHuRef
CHM1_12220,796,082 - 20,850,455 (-)NCBICHM1_1
T2T-CHM13v2.02220,845,791 - 20,900,118 (-)NCBIT2T-CHM13v2.0
Klhl22
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391617,577,485 - 17,611,246 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1617,577,482 - 17,611,246 (+)EnsemblGRCm39 Ensembl
GRCm381617,759,621 - 17,793,382 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1617,759,618 - 17,793,382 (+)EnsemblGRCm38mm10GRCm38
MGSCv371617,759,714 - 17,793,475 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361617,673,234 - 17,706,943 (+)NCBIMGSCv36mm8
Celera1618,332,703 - 18,366,464 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.01NCBI
Klhl22
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544219,009,155 - 19,051,393 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544219,010,971 - 19,051,300 (-)NCBIChiLan1.0ChiLan1.0
KLHL22
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan12232,609,513 - 32,664,017 (-)NCBINHGRI_mPanPan1
PanPan1.12219,126,658 - 19,174,839 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2219,122,875 - 19,174,842 (-)Ensemblpanpan1.1panPan2
KLHL22
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12630,248,253 - 30,281,989 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2630,248,240 - 30,281,843 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2630,207,137 - 30,246,532 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02631,656,570 - 31,696,204 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2631,656,561 - 31,696,176 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12629,702,711 - 29,742,120 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02629,327,051 - 29,366,309 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02630,416,255 - 30,455,878 (-)NCBIUU_Cfam_GSD_1.0
Klhl22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118139,854,676 - 139,899,247 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366192,854,803 - 2,899,460 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366192,854,915 - 2,899,386 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL22
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1450,773,964 - 50,809,986 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11450,773,917 - 50,809,991 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21454,334,392 - 54,451,824 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL22
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1195,211,732 - 5,264,953 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl195,218,653 - 5,265,063 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660851,671,542 - 1,725,149 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klhl22
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624945408,999 - 441,975 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624945409,093 - 446,619 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Klhl22
203 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:65
Count of miRNA genes:59
Interacting mature miRNAs:62
Transcripts:ENSRNOT00000068711
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
2302043Pia27Pristane induced arthritis QTL 2718.60.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)118256654583440803Rat

Markers in Region
RH138822  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21183,191,424 - 83,191,545 (-)MAPPERmRatBN7.2
Rnor_6.01187,718,154 - 87,718,274NCBIRnor6.0
Rnor_5.01190,770,599 - 90,770,719UniSTSRnor5.0
RGSC_v3.41185,179,793 - 85,179,913UniSTSRGSC3.4
Celera1181,963,267 - 81,963,387UniSTS
RH 3.4 Map11710.1UniSTS
Cytogenetic Map11q23UniSTS
RH131807  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21183,191,027 - 83,191,210 (-)MAPPERmRatBN7.2
Rnor_6.01187,718,489 - 87,718,671NCBIRnor6.0
Rnor_5.01190,770,934 - 90,771,116UniSTSRnor5.0
RGSC_v3.41185,179,396 - 85,179,578UniSTSRGSC3.4
Celera1181,962,870 - 81,963,052UniSTS
RH 3.4 Map11707.6UniSTS
Cytogenetic Map11q23UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 35 44 28 19 28 8 11 74 35 36 11 8
Low 2 8 13 13 13 5
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000068711   ⟹   ENSRNOP00000063573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1183,190,891 - 83,231,770 (-)Ensembl
Rnor_6.0 Ensembl1187,677,966 - 87,718,805 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091675   ⟹   ENSRNOP00000075207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1183,190,891 - 83,231,748 (-)Ensembl
Rnor_6.0 Ensembl1187,678,295 - 87,718,826 (+)Ensembl
RefSeq Acc Id: NM_001107079   ⟹   NP_001100549
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,190,894 - 83,231,738 (-)NCBI
Rnor_6.01187,677,966 - 87,718,805 (+)NCBI
Rnor_5.01190,699,112 - 90,771,253 (+)NCBI
RGSC_v3.41185,179,262 - 85,220,103 (-)RGD
Celera1181,962,736 - 82,003,585 (-)RGD
Sequence:
RefSeq Acc Id: XM_006248699   ⟹   XP_006248761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,190,891 - 83,231,670 (-)NCBI
Rnor_6.01187,678,203 - 87,718,808 (+)NCBI
Rnor_5.01190,699,112 - 90,771,253 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248700   ⟹   XP_006248762
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,190,891 - 83,231,671 (-)NCBI
Rnor_6.01187,678,202 - 87,718,808 (+)NCBI
Rnor_5.01190,699,112 - 90,771,253 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039088267   ⟹   XP_038944195
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21183,190,891 - 83,231,746 (-)NCBI
RefSeq Acc Id: NP_001100549   ⟸   NM_001107079
- UniProtKB: D4A9W5 (UniProtKB/Swiss-Prot),   D3ZZC3 (UniProtKB/Swiss-Prot),   A0A0G2KA06 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248762   ⟸   XM_006248700
- Peptide Label: isoform X2
- UniProtKB: A0A0G2KA06 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248761   ⟸   XM_006248699
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QUL2 (UniProtKB/TrEMBL),   A0A0G2KA06 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000063573   ⟸   ENSRNOT00000068711
RefSeq Acc Id: ENSRNOP00000075207   ⟸   ENSRNOT00000091675
RefSeq Acc Id: XP_038944195   ⟸   XM_039088267
- Peptide Label: isoform X3
Protein Domains
BTB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZC3-F1-model_v2 AlphaFold D3ZZC3 1-634 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698324
Promoter ID:EPDNEW_R8849
Type:initiation region
Name:Klhl22_1
Description:kelch-like family member 22
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01187,677,946 - 87,678,006EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306288 AgrOrtholog
BioCyc Gene G2FUF-20611 BioCyc
Ensembl Genes ENSRNOG00000001878 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055003606 UniProtKB/Swiss-Prot
  ENSRNOG00060012995 UniProtKB/Swiss-Prot
  ENSRNOG00065008036 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000068711 ENTREZGENE
  ENSRNOT00000068711.3 UniProtKB/TrEMBL
  ENSRNOT00000091675 ENTREZGENE
  ENSRNOT00000091675.2 UniProtKB/TrEMBL
  ENSRNOT00055005647 UniProtKB/Swiss-Prot
  ENSRNOT00060022129 UniProtKB/Swiss-Prot
  ENSRNOT00065012693 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.420 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro BACK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB-kelch_protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KLHL22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:303792 UniProtKB/Swiss-Prot
NCBI Gene 303792 ENTREZGENE
PANTHER LD33804P UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45632:SF5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BACK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Klhl22 PhenoGen
PIRSF Kelch-like_protein_gigaxonin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001878 RatGTEx
  ENSRNOG00055003606 RatGTEx
  ENSRNOG00060012995 RatGTEx
  ENSRNOG00065008036 RatGTEx
SMART BACK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF117281 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54695 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2KA06 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QUL2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZZC3 ENTREZGENE
  D4A9W5 ENTREZGENE
  KLH22_RAT UniProtKB/Swiss-Prot
UniProt Secondary D4A9W5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-06 Klhl22  kelch-like family member 22  Klhl22  kelch-like 22 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Klhl22  kelch-like 22 (Drosophila)   Klhl22_predicted  kelch-like 22 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Klhl22_predicted  kelch-like 22 (Drosophila) (predicted)  RGD1306288_predicted  similar to hypothetical protein FLJ14360 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1306288_predicted  similar to hypothetical protein FLJ14360 (predicted)  LOC303792_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC303792_predicted  similar to hypothetical protein FLJ14360 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL