Spin1 (spindlin 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Spin1 (spindlin 1) Rattus norvegicus
Analyze
Symbol: Spin1
Name: spindlin 1
RGD ID: 1306210
Description: Predicted to enable methylated histone binding activity. Predicted to be involved in positive regulation of DNA-templated transcription; positive regulation of Wnt signaling pathway; and rRNA transcription. Predicted to be located in nuclear membrane; nucleolus; and spindle. Predicted to be active in cytosol and nucleoplasm. Orthologous to human SPIN1 (spindlin 1); PARTICIPATES IN histone modification pathway; INTERACTS WITH 17alpha-ethynylestradiol; 3-chloropropane-1,2-diol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC361217; NEWGENE_1306210; Spin; spindlin; spindlin-1; spindlin1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81714,207,384 - 14,257,330 (-)NCBIGRCr8
mRatBN7.21714,055,685 - 14,105,366 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1714,055,689 - 14,105,411 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1713,984,497 - 14,030,225 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01715,589,742 - 15,635,421 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01713,911,319 - 13,957,038 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.016884,854 - 930,527 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl16884,861 - 930,527 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01716,148,547 - 16,195,282 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41719,950,350 - 19,996,991 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11719,950,350 - 19,996,991 (-)NCBI
Celera16203,774 - 204,818 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IBA,ISO)
nuclear membrane  (ISO)
nucleolus  (ISO,ISS)
nucleoplasm  (IBA,ISO)
nucleus  (IEA,ISO,ISS)
spindle  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Tudor: a versatile family of histone methylation 'readers'. Lu R and Wang GG, Trends Biochem Sci. 2013 Nov;38(11):546-55. doi: 10.1016/j.tibs.2013.08.002. Epub 2013 Sep 10.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:9053325   PMID:9590541   PMID:12477932   PMID:15489334   PMID:21029866   PMID:21960006   PMID:23077255   PMID:24589551   PMID:29061846   PMID:31378911  


Genomics

Comparative Map Data
Spin1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81714,207,384 - 14,257,330 (-)NCBIGRCr8
mRatBN7.21714,055,685 - 14,105,366 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1714,055,689 - 14,105,411 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1713,984,497 - 14,030,225 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01715,589,742 - 15,635,421 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01713,911,319 - 13,957,038 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.016884,854 - 930,527 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl16884,861 - 930,527 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01716,148,547 - 16,195,282 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41719,950,350 - 19,996,991 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11719,950,350 - 19,996,991 (-)NCBI
Celera16203,774 - 204,818 (-)NCBICelera
Cytogenetic Map17p14NCBI
SPIN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38988,388,444 - 88,478,694 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl988,388,430 - 88,478,694 (+)EnsemblGRCh38hg38GRCh38
GRCh37991,003,359 - 91,093,609 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36990,193,117 - 90,283,443 (+)NCBINCBI36Build 36hg18NCBI36
Build 34988,232,968 - 88,320,261NCBI
Celera961,579,528 - 61,669,853 (+)NCBICelera
Cytogenetic Map9q22.1NCBI
HuRef960,869,908 - 60,922,040 (+)NCBIHuRef
CHM1_1991,150,928 - 91,241,252 (+)NCBICHM1_1
T2T-CHM13v2.09100,542,547 - 100,632,795 (+)NCBIT2T-CHM13v2.0
Spin1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391351,254,523 - 51,306,588 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1351,254,916 - 51,306,582 (+)EnsemblGRCm39 Ensembl
GRCm381351,097,934 - 51,152,562 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1351,100,880 - 51,152,546 (+)EnsemblGRCm38mm10GRCm38
MGSCv371351,196,267 - 51,247,915 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361351,113,395 - 51,165,043 (+)NCBIMGSCv36mm8
Celera1352,196,100 - 52,225,469 (+)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1326.04NCBI
Spin1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555153,470,956 - 3,513,728 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555153,470,956 - 3,518,909 (-)NCBIChiLan1.0ChiLan1.0
SPIN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21150,992,872 - 51,087,039 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1950,995,264 - 51,089,744 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0959,466,550 - 59,558,773 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1987,513,819 - 87,606,187 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl987,513,819 - 87,606,183 (+)Ensemblpanpan1.1panPan2
SPIN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1197,353,108 - 97,426,563 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl197,356,125 - 97,390,646 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha197,815,602 - 97,890,611 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0197,964,655 - 98,039,704 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl197,965,031 - 98,038,858 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1197,592,282 - 97,667,272 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0197,311,443 - 97,386,464 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0198,069,975 - 98,144,932 (-)NCBIUU_Cfam_GSD_1.0
Spin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494410,187,095 - 10,254,730 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936854448,296 - 516,355 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936854448,403 - 516,251 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPIN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14227,209 - 294,826 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114227,219 - 291,420 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214418,141 - 534,760 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SPIN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11298,880,918 - 98,964,988 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1298,913,798 - 98,960,934 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603887,213,604 - 87,297,382 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spin1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476524,222,380 - 24,271,046 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476524,223,499 - 24,271,049 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Spin1
119 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:15
Count of miRNA genes:15
Interacting mature miRNAs:15
Transcripts:ENSRNOT00000014787
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920136523653323Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1582208Kidm32Kidney mass QTL 323.90.0018kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17920136523653323Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)171398677321975515Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17429913021293263Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
1581553Pur14Proteinuria QTL 145.30.0001urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)17797996816317111Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
1582258Bw76Body weight QTL 764.60.0005body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1582199Insul5Insulin level QTL 53.40.0119blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)17920136523653323Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17435448727028127Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17211514921881669Rat
1582241Bw70Body weight QTL 704.60.0003body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582245Bw73Body weight QTL 734.60.0004body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122871563Rat

Markers in Region
RH124326  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22104,592,140 - 104,592,589 (+)MAPPERmRatBN7.2
mRatBN7.216217,250 - 217,699 (-)MAPPERmRatBN7.2
mRatBN7.22148,724,497 - 148,724,942 (+)MAPPERmRatBN7.2
Rnor_6.02109,317,489 - 109,317,937NCBIRnor6.0
Rnor_6.02155,282,443 - 155,282,887NCBIRnor6.0
Rnor_5.02174,676,861 - 174,677,305UniSTSRnor5.0
Rnor_5.02129,043,433 - 129,043,881UniSTSRnor5.0
Cytogenetic Map17p14UniSTS
Cytogenetic Map2q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000014787   ⟹   ENSRNOP00000014787
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1714,059,097 - 14,105,347 (-)Ensembl
Rnor_6.0 Ensembl16884,861 - 930,527 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095885   ⟹   ENSRNOP00000088564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1714,055,689 - 14,090,596 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106752   ⟹   ENSRNOP00000094195
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1714,055,689 - 14,105,411 (-)Ensembl
RefSeq Acc Id: NM_001024796   ⟹   NP_001019967
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81714,207,384 - 14,256,507 (-)NCBI
mRatBN7.21714,055,685 - 14,104,811 (-)NCBI
Rnor_6.016884,856 - 930,527 (-)NCBI
Rnor_5.01716,148,547 - 16,195,282 (-)NCBI
RGSC_v3.41719,950,350 - 19,996,991 (-)RGD
Celera16203,774 - 204,818 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001419143   ⟹   NP_001406072
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81714,207,384 - 14,257,062 (-)NCBI
mRatBN7.21714,055,685 - 14,105,366 (-)NCBI
RefSeq Acc Id: NM_001419144   ⟹   NP_001406073
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81714,207,384 - 14,257,062 (-)NCBI
mRatBN7.21714,055,685 - 14,105,366 (-)NCBI
RefSeq Acc Id: NM_001419145   ⟹   NP_001406074
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81714,207,384 - 14,257,062 (-)NCBI
mRatBN7.21714,055,685 - 14,105,366 (-)NCBI
RefSeq Acc Id: XM_063276559   ⟹   XP_063132629
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81714,207,388 - 14,257,330 (-)NCBI
RefSeq Acc Id: XM_063276560   ⟹   XP_063132630
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81714,207,388 - 14,256,632 (-)NCBI
RefSeq Acc Id: NP_001019967   ⟸   NM_001024796
- Peptide Label: isoform 1
- UniProtKB: Q4V8J7 (UniProtKB/Swiss-Prot),   A6J6U6 (UniProtKB/TrEMBL),   A0A8L2Q712 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014787   ⟸   ENSRNOT00000014787
Ensembl Acc Id: ENSRNOP00000094195   ⟸   ENSRNOT00000106752
Ensembl Acc Id: ENSRNOP00000088564   ⟸   ENSRNOT00000095885
RefSeq Acc Id: NP_001406073   ⟸   NM_001419144
- Peptide Label: isoform 2
- UniProtKB: A0A8I6A4I2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001406074   ⟸   NM_001419145
- Peptide Label: isoform 3
- UniProtKB: A0A8I6AKH2 (UniProtKB/TrEMBL),   A6J6U5 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001406072   ⟸   NM_001419143
- Peptide Label: isoform 1
- UniProtKB: Q4V8J7 (UniProtKB/Swiss-Prot),   A0A8L2Q712 (UniProtKB/TrEMBL),   A6J6U6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132629   ⟸   XM_063276559
- Peptide Label: isoform X1
- UniProtKB: Q4V8J7 (UniProtKB/Swiss-Prot),   A0A8L2Q712 (UniProtKB/TrEMBL),   A6J6U6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132630   ⟸   XM_063276560
- Peptide Label: isoform X1
- UniProtKB: Q4V8J7 (UniProtKB/Swiss-Prot),   A0A8L2Q712 (UniProtKB/TrEMBL),   A6J6U6 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4V8J7-F1-model_v2 AlphaFold Q4V8J7 1-262 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306210 AgrOrtholog
BioCyc Gene G2FUF-10062 BioCyc
Ensembl Genes ENSRNOG00000011119 Ensembl
  ENSRNOG00000031378 UniProtKB/TrEMBL
  ENSRNOG00000064787 UniProtKB/TrEMBL
  ENSRNOG00000067284 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055004652 UniProtKB/Swiss-Prot
  ENSRNOG00055013696 UniProtKB/Swiss-Prot
  ENSRNOG00060001583 UniProtKB/Swiss-Prot
  ENSRNOG00060021785 UniProtKB/Swiss-Prot
  ENSRNOG00065010419 UniProtKB/Swiss-Prot
  ENSRNOG00065027241 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000014787.6 UniProtKB/TrEMBL
  ENSRNOT00000049885.5 UniProtKB/TrEMBL
  ENSRNOT00000095885.1 UniProtKB/Swiss-Prot
  ENSRNOT00000106752.1 UniProtKB/TrEMBL
  ENSRNOT00000106994.1 UniProtKB/TrEMBL
  ENSRNOT00055007396 UniProtKB/Swiss-Prot
  ENSRNOT00055023519 UniProtKB/Swiss-Prot
  ENSRNOT00060002386 UniProtKB/Swiss-Prot
  ENSRNOT00060037735 UniProtKB/Swiss-Prot
  ENSRNOT00065016861 UniProtKB/Swiss-Prot
  ENSRNOT00065046967 UniProtKB/Swiss-Prot
Gene3D-CATH 2.80.10.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7442223 IMAGE-MGC_LOAD
InterPro SPIN/Ssty UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPIN/Ssty_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:361217 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:114391 IMAGE-MGC_LOAD
NCBI Gene 361217 ENTREZGENE
PANTHER PTHR10405 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10405:SF15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Spin-Ssty UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Spin1 PhenoGen
RatGTEx ENSRNOG00000011119 RatGTEx
  ENSRNOG00000031378 RatGTEx
  ENSRNOG00000064787 RatGTEx
  ENSRNOG00000067284 RatGTEx
  ENSRNOG00055004652 RatGTEx
  ENSRNOG00055013696 RatGTEx
  ENSRNOG00060001583 RatGTEx
  ENSRNOG00060021785 RatGTEx
  ENSRNOG00065010419 RatGTEx
  ENSRNOG00065027241 RatGTEx
UniProt A0A8I6A4I2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AKH2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALN2_RAT UniProtKB/TrEMBL
  A0A8L2Q712 ENTREZGENE, UniProtKB/TrEMBL
  A6J6U5 ENTREZGENE, UniProtKB/TrEMBL
  A6J6U6 ENTREZGENE, UniProtKB/TrEMBL
  Q4V8J7 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Spin1  spindlin 1  NEWGENE_1306210  spindlin 1  Data merged from RGD:11436999 737654 PROVISIONAL
2016-08-02 NEWGENE_1306210  spindlin 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-07 Spin1  spindlin 1  Spin  spindlin  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Spin  spindlin  Spin_predicted  spindlin (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Spin_predicted  spindlin (predicted)      Symbol and Name status set to approved 70820 APPROVED