Tbc1d24 (TBC1 domain family, member 24) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Tbc1d24 (TBC1 domain family, member 24) Rattus norvegicus
Analyze
Symbol: Tbc1d24
Name: TBC1 domain family, member 24
RGD ID: 1306143
Description: Involved in positive regulation of dendrite morphogenesis; positive regulation of excitatory postsynaptic potential; and positive regulation of neuron migration. Predicted to be located in cytoplasm; neuromuscular junction; and terminal bouton. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in DOORS syndrome; epilepsy (multiple); and nonsyndromic deafness (multiple). Orthologous to human TBC1D24 (TBC1 domain family member 24); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC287110; RGD1306143; similar to CG9339-PA; TBC1 domain family member 24
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,711,930 - 13,740,902 (-)NCBIGRCr8
mRatBN7.21013,205,819 - 13,236,013 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,209,895 - 13,236,050 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1017,955,085 - 17,980,715 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,443,924 - 17,469,554 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01012,942,419 - 12,968,398 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,551,100 - 13,576,739 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,551,100 - 13,558,384 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,367,060 - 13,392,774 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,429,738 - 13,456,667 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11013,432,283 - 13,444,158 (-)NCBI
Celera1012,896,302 - 12,921,877 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. TBC1D24 mutation causes autosomal-dominant nonsyndromic hearing loss. Azaiez H, etal., Hum Mutat. 2014 Jul;35(7):819-23. doi: 10.1002/humu.22557. Epub 2014 May 6.
2. Recessive TBC1D24 Mutations Are Frequent in Moroccan Non-Syndromic Hearing Loss Pedigrees. Bakhchane A, etal., PLoS One. 2015 Sep 15;10(9):e0138072. doi: 10.1371/journal.pone.0138072. eCollection 2015.
3. A focal epilepsy and intellectual disability syndrome is due to a mutation in TBC1D24. Corbett MA, etal., Am J Hum Genet. 2010 Sep 10;87(3):371-5. doi: 10.1016/j.ajhg.2010.08.001.
4. TBC1D24 regulates neuronal migration and maturation through modulation of the ARF6-dependent pathway. Falace A, etal., Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2337-42. doi: 10.1073/pnas.1316294111. Epub 2014 Jan 27.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Novel compound heterozygous mutations in TBC1D24 cause familial malignant migrating partial seizures of infancy. Milh M, etal., Hum Mutat. 2013 Jun;34(6):869-72. doi: 10.1002/humu.22318. Epub 2013 Apr 12.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Homozygous TBC1D24 mutation in two siblings with familial infantile myoclonic epilepsy (FIME) and moderate intellectual disability. Poulat AL, etal., Epilepsy Res. 2015 Mar;111:72-7. doi: 10.1016/j.eplepsyres.2015.01.008. Epub 2015 Jan 25.
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:17646400   PMID:20727515   PMID:26668325   PMID:30335140  


Genomics

Comparative Map Data
Tbc1d24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,711,930 - 13,740,902 (-)NCBIGRCr8
mRatBN7.21013,205,819 - 13,236,013 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,209,895 - 13,236,050 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1017,955,085 - 17,980,715 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,443,924 - 17,469,554 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01012,942,419 - 12,968,398 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,551,100 - 13,576,739 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,551,100 - 13,558,384 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,367,060 - 13,392,774 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,429,738 - 13,456,667 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11013,432,283 - 13,444,158 (-)NCBI
Celera1012,896,302 - 12,921,877 (-)NCBICelera
Cytogenetic Map10q12NCBI
TBC1D24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,475,127 - 2,505,730 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,475,051 - 2,509,671 (+)EnsemblGRCh38hg38GRCh38
GRCh37162,525,128 - 2,555,731 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,465,148 - 2,493,500 (+)NCBINCBI36Build 36hg18NCBI36
Celera162,760,729 - 2,768,193 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef162,472,128 - 2,481,831 (+)NCBIHuRef
CHM1_1162,525,041 - 2,555,671 (+)NCBICHM1_1
T2T-CHM13v2.0162,497,257 - 2,531,799 (+)NCBIT2T-CHM13v2.0
Tbc1d24
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,394,405 - 24,424,536 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,394,405 - 24,424,536 (-)EnsemblGRCm39 Ensembl
GRCm381724,175,431 - 24,205,562 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,175,431 - 24,205,562 (-)EnsemblGRCm38mm10GRCm38
MGSCv371724,312,376 - 24,342,507 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361723,906,386 - 23,933,115 (-)NCBIMGSCv36mm8
Celera1724,680,659 - 24,710,996 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.3NCBI
Tbc1d24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544214,812,566 - 14,823,224 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544214,816,213 - 14,823,132 (-)NCBIChiLan1.0ChiLan1.0
TBC1D24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,976,738 - 3,011,361 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,757,748 - 6,788,439 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,331,630 - 1,362,320 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1162,581,835 - 2,603,919 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl162,581,835 - 2,603,912 (+)Ensemblpanpan1.1panPan2
TBC1D24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,531,547 - 38,557,472 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha639,769,612 - 39,796,058 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0638,840,471 - 38,866,927 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl638,840,528 - 38,866,914 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,525,620 - 38,552,059 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,498,219 - 38,524,683 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0638,974,367 - 39,000,835 (-)NCBIUU_Cfam_GSD_1.0
Tbc1d24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344105,145,718 - 105,151,782 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,556,244 - 1,569,201 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,556,717 - 1,582,019 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBC1D24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,545,218 - 39,571,277 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,545,688 - 39,572,320 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2342,686,824 - 42,691,216 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TBC1D24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,353,543 - 2,378,950 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606828,651,927 - 28,683,478 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbc1d24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624824243,939 - 254,249 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624824245,717 - 251,603 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tbc1d24
185 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:226
Count of miRNA genes:163
Interacting mature miRNAs:183
Transcripts:ENSRNOT00000009105
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10129497586Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402719233348Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402717245662Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10615418215990232Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10476552719816042Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000081995   ⟹   ENSRNOP00000071746
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,209,895 - 13,235,901 (-)Ensembl
Rnor_6.0 Ensembl1013,551,100 - 13,558,384 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000084066   ⟹   ENSRNOP00000073359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,209,895 - 13,236,050 (-)Ensembl
Rnor_6.0 Ensembl1013,553,629 - 13,558,377 (-)Ensembl
RefSeq Acc Id: NM_001105769   ⟹   NP_001099239
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,714,833 - 13,740,473 (-)NCBI
mRatBN7.21013,210,275 - 13,235,919 (-)NCBI
Rnor_6.01013,551,100 - 13,576,739 (-)NCBI
Rnor_5.01013,367,060 - 13,392,774 (-)NCBI
RGSC_v3.41013,429,738 - 13,456,667 (-)RGD
Celera1012,896,302 - 12,921,877 (-)RGD
Sequence:
RefSeq Acc Id: XM_039085349   ⟹   XP_038941277
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,711,930 - 13,740,378 (-)NCBI
mRatBN7.21013,210,562 - 13,235,836 (-)NCBI
RefSeq Acc Id: XM_039085350   ⟹   XP_038941278
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,711,930 - 13,740,902 (-)NCBI
mRatBN7.21013,210,562 - 13,236,012 (-)NCBI
RefSeq Acc Id: XR_005489713
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,711,930 - 13,740,902 (-)NCBI
mRatBN7.21013,210,035 - 13,236,013 (-)NCBI
RefSeq Acc Id: XR_010055133
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,711,930 - 13,740,902 (-)NCBI
RefSeq Acc Id: XR_010055134
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,711,930 - 13,740,902 (-)NCBI
RefSeq Acc Id: XR_010055136
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,711,930 - 13,740,902 (-)NCBI
RefSeq Acc Id: XR_010055137
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,711,930 - 13,740,902 (-)NCBI
RefSeq Acc Id: XR_010055138
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,718,911 - 13,740,902 (-)NCBI
RefSeq Acc Id: XR_357445
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,711,930 - 13,740,902 (-)NCBI
mRatBN7.21013,210,562 - 13,236,013 (-)NCBI
Rnor_6.01013,551,731 - 13,558,287 (-)NCBI
Rnor_5.01013,367,060 - 13,392,774 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001099239 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941277 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941278 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM03813 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000071746
  ENSRNOP00000071746.1
  ENSRNOP00000073359
  ENSRNOP00000073359.1
RefSeq Acc Id: NP_001099239   ⟸   NM_001105769
- UniProtKB: D4A3Z3 (UniProtKB/TrEMBL),   A6HCQ8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071746   ⟸   ENSRNOT00000081995
Ensembl Acc Id: ENSRNOP00000073359   ⟸   ENSRNOT00000084066
RefSeq Acc Id: XP_038941278   ⟸   XM_039085350
- Peptide Label: isoform X2
- UniProtKB: D4A3Z3 (UniProtKB/TrEMBL),   A6HCQ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941277   ⟸   XM_039085349
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K5B0 (UniProtKB/TrEMBL)
Protein Domains
TLDc

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K5B0-F1-model_v2 AlphaFold A0A0G2K5B0 1-562 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306143 AgrOrtholog
BioCyc Gene G2FUF-25872 BioCyc
Ensembl Genes ENSRNOG00000052204 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000081995 ENTREZGENE
  ENSRNOT00000081995.2 UniProtKB/TrEMBL
  ENSRNOT00000084066 ENTREZGENE
  ENSRNOT00000084066.2 UniProtKB/TrEMBL
Gene3D-CATH Ypt/Rab-GAP domain of gyp1p, domain 3 UniProtKB/TrEMBL
InterPro Rab-GTPase_TBC_sf UniProtKB/TrEMBL
  RabGAP_TBC UniProtKB/TrEMBL
  TLDc UniProtKB/TrEMBL
KEGG Report rno:287110 UniProtKB/TrEMBL
NCBI Gene 287110 ENTREZGENE
PANTHER GTPASE-ACTIVATING PROTEIN SKYWALKER UniProtKB/TrEMBL
  NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED UniProtKB/TrEMBL
Pfam TBC UniProtKB/TrEMBL
  TLD UniProtKB/TrEMBL
PhenoGen Tbc1d24 PhenoGen
PROSITE TLDC UniProtKB/TrEMBL
RatGTEx ENSRNOG00000052204 RatGTEx
SMART TBC UniProtKB/TrEMBL
  TLDc UniProtKB/TrEMBL
Superfamily-SCOP RabGAP_TBC UniProtKB/TrEMBL
UniProt A0A0G2K5B0 ENTREZGENE, UniProtKB/TrEMBL
  A6HCQ8 ENTREZGENE, UniProtKB/TrEMBL
  D4A3Z3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Tbc1d24  TBC1 domain family, member 24  RGD1306143_predicted  similar to CG9339-PA (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1306143_predicted  similar to CG9339-PA (predicted)  LOC287110_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC287110_predicted  similar to CG9339-PA (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL