Gene: Txndc12 (thioredoxin domain containing 12) Rattus norvegicus
Symbol: Txndc12
Name: thioredoxin domain containing 12
Description: Predicted to have peptide disulfide oxidoreductase activity. Predicted to be involved in negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. Predicted to localize to the endoplasmic reticulum lumen. Orthologous to human TXNDC12 (thioredoxin domain containing 12); PARTICIPATES IN glutathione metabolic pathway; INTERACTS WITH bisphenol A; tetrachloromethane; vinclozolin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC298370; RGD1305960; similar to RIKEN cDNA 0610040B21; thioredoxin domain containing 12 (endoplasmic reticulum); thioredoxin domain-containing protein 12
Homo sapiens (human) : TXNDC12 (thioredoxin domain containing 12)  HGNC  Alliance
Mus musculus (house mouse) : Txndc12 (thioredoxin domain containing 12 (endoplasmic reticulum))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Txndc12 (thioredoxin domain containing 12)
Pan paniscus (bonobo/pygmy chimpanzee) : TXNDC12 (thioredoxin domain containing 12)
Canis lupus familiaris (dog) : TXNDC12 (thioredoxin domain containing 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Txndc12 (thioredoxin domain containing 12)
Sus scrofa (pig) : TXNDC12 (thioredoxin domain containing 12)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05128,450,830 - 128,475,858 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05132,291,196 - 132,316,224 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45130,142,600 - 130,167,629 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15130,147,623 - 130,172,855 (+)NCBI
Celera5122,322,074 - 122,347,022 (+)NCBICelera
Cytogenetic Map5q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Txndc12
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305960
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.