Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Krit1 (KRIT1, ankyrin repeat containing) Rattus norvegicus
Analyze
Symbol: Krit1
Name: KRIT1, ankyrin repeat containing
Description: Predicted to have microtubule binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in several processes, including cell redox homeostasis; negative regulation of endothelial cell apoptotic process; and negative regulation of endothelial cell migration. Predicted to localize to several cellular components, including the cell-cell junction; microtubule; and plasma membrane. Human ortholog(s) of this gene implicated in cerebral cavernous malformation and cerebral cavernous malformation 1. Orthologous to human KRIT1 (KRIT1 ankyrin repeat containing); PARTICIPATES IN integrin mediated signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; chloroprene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Krev interaction trapped protein 1; LOC362317; LOC362318; RGD1305929; similar to Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog); similar to KRIT1
Orthologs:
Homo sapiens (human) : KRIT1 (KRIT1 ankyrin repeat containing)  HGNC  Alliance
Mus musculus (house mouse) : Krit1 (KRIT1, ankyrin repeat containing)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Krit1 (KRIT1 ankyrin repeat containing)
Pan paniscus (bonobo/pygmy chimpanzee) : KRIT1 (KRIT1 ankyrin repeat containing)
Canis lupus familiaris (dog) : KRIT1 (KRIT1 ankyrin repeat containing)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Krit1 (KRIT1 ankyrin repeat containing)
Sus scrofa (pig) : KRIT1 (KRIT1 ankyrin repeat containing)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0427,438,609 - 27,473,150 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0427,341,835 - 27,376,376 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4427,014,488 - 27,048,636 (-)NCBIRGSC3.4rn4RGSC3.4
Celera425,724,169 - 25,758,310 (-)NCBICelera
Cytogenetic Map4q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Krit1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305929
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.