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Gene: Krit1 (KRIT1, ankyrin repeat containing) Rattus norvegicus
Symbol: Krit1
Name: KRIT1, ankyrin repeat containing
RGD ID: 1305929
Description: Predicted to have microtubule binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in several processes, including cell redox homeostasis; negative regulation of endothelial cell apoptotic process; and negative regulation of endothelial cell migration. Predicted to localize to several cellular components, including cell-cell junction; cytoplasm; and plasma membrane. Human ortholog(s) of this gene implicated in cerebral cavernous malformation and cerebral cavernous malformation 1. Orthologous to human KRIT1 (KRIT1 ankyrin repeat containing); PARTICIPATES IN integrin mediated signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; chloroprene.
Type: protein-coding
Also known as: Krev interaction trapped protein 1; LOC362317; LOC362318; RGD1305929; similar to Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog); similar to KRIT1
Homo sapiens (human) : KRIT1 (KRIT1 ankyrin repeat containing)  HGNC  Alliance
Mus musculus (house mouse) : Krit1 (KRIT1, ankyrin repeat containing)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Krit1 (KRIT1 ankyrin repeat containing)
Pan paniscus (bonobo/pygmy chimpanzee) : KRIT1 (KRIT1 ankyrin repeat containing)
Canis lupus familiaris (dog) : KRIT1 (KRIT1 ankyrin repeat containing)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Krit1 (KRIT1 ankyrin repeat containing)
Sus scrofa (pig) : KRIT1 (KRIT1 ankyrin repeat containing)
Chlorocebus sabaeus (African green monkey) : KRIT1 (KRIT1 ankyrin repeat containing)
Heterocephalus glaber (naked mole-rat) : Krit1 (KRIT1 ankyrin repeat containing)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0427,438,609 - 27,473,150 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl427,438,609 - 27,473,150 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0427,341,835 - 27,376,376 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4427,014,488 - 27,048,636 (-)NCBIRGSC3.4rn4RGSC3.4
Celera425,724,169 - 25,758,310 (-)NCBICelera
Cytogenetic Map4q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Krit1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305929
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.