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Gene: Mrrf (mitochondrial ribosome recycling factor) Rattus norvegicus
Analyze
Symbol:
Mrrf
Name:
mitochondrial ribosome recycling factor
RGD ID:
1305897
Description:
Predicted to have ribosomal large subunit binding activity. Predicted to be involved in ribosome disassembly and translation. Predicted to localize to mitochondrion. Orthologous to human MRRF (mitochondrial ribosome recycling factor); INTERACTS WITH 2,4,6-trinitrotoluene; acrylamide; bisphenol A.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
LOC311903; MGC93722; ribosome-recycling factor, mitochondrial; ribosome-releasing factor, mitochondrial; RRF
RGD Orthologs
Alliance Genes
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
MRRF (mitochondrial ribosome recycling factor)
HGNC
EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Mrrf (mitochondrial ribosome recycling factor)
HGNC
Inparanoid, OrthoDB
Chinchilla lanigera (long-tailed chinchilla):
Mrrf (mitochondrial ribosome recycling factor)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
MRRF (mitochondrial ribosome recycling factor)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
MRRF (mitochondrial ribosome recycling factor)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Mrrf (mitochondrial ribosome recycling factor)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
MRRF (mitochondrial ribosome recycling factor)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
MRRF (mitochondrial ribosome recycling factor)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Mrrf (mitochondrial ribosome recycling factor)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
MRRFP1 (mitochondrial ribosome recycling factor pseudogene 1)
HGNC
Inparanoid
Alliance orthologs 3
Homo sapiens (human):
MRRF (mitochondrial ribosome recycling factor)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Mus musculus (house mouse):
Mrrf (mitochondrial ribosome recycling factor)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Danio rerio (zebrafish):
mrrf (mitochondrial ribosome recycling factor)
Alliance
DIOPT (PhylomeDB|TreeFam)
Caenorhabditis elegans (roundworm):
mrrf-1
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):
RRF1
Alliance
DIOPT (Ensembl Compara|Hieranoid|OrthoFinder|PANTHER|PhylomeDB)
Drosophila melanogaster (fruit fly):
mRRF1
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 3 15,463,884 - 15,520,621 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 15,463,953 - 15,520,618 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 3 20,773,131 - 20,829,833 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 3 15,247,054 - 15,303,722 (+) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 3 15,143,425 - 15,200,091 (+) NCBI Celera 3 14,199,058 - 14,255,750 (+) NCBI Celera Cytogenetic Map 3 p11 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
1,2-dimethylhydrazine affects expression ISO RGD:1314202 6480464 1, 2-Dimethylhydrazine affects the expression of MRRF mRNA CTD PMID:22206623 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1314202 6480464 Tetrachlorodibenzodioxin affects the expression of MRRF mRNA CTD PMID:24058054 2,4,6-trinitrotoluene affects expression EXP 6480464 Trinitrotoluene affects the expression of MRRF mRNA CTD PMID:21346803 acrolein multiple interactions ISO RGD:1314201 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of MRRF mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of MRRF mRNA CTD PMID:32699268 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of MRRF mRNA CTD PMID:28959563 aflatoxin B1 increases methylation ISO RGD:1314201 6480464 Aflatoxin B1 results in increased methylation of MRRF gene CTD PMID:27153756 all-trans-retinoic acid decreases expression ISO RGD:1314201 6480464 Tretinoin results in decreased expression of MRRF mRNA CTD PMID:23724009 alpha-pinene multiple interactions ISO RGD:1314201 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of MRRF mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of MRRF mRNA CTD PMID:32699268 atrazine decreases expression ISO RGD:1314201 6480464 Atrazine results in decreased expression of MRRF mRNA CTD PMID:22378314 benzo[a]pyrene decreases expression ISO RGD:1314202 6480464 Benzoapyrene results in decreased expression of MRRF mRNA CTD PMID:22228805 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of MRRF mRNA CTD PMID:25181051 , PMID:30816183 cis-caffeic acid multiple interactions ISO RGD:1314201 6480464 caffeic acid promotes the reaction [Thapsigargin results in decreased expression of MRRF mRNA] CTD PMID:19442820 dorsomorphin multiple interactions ISO RGD:1314201 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of MRRF mRNA CTD PMID:27188386 folic acid decreases expression ISO RGD:1314202 6480464 Folic Acid results in decreased expression of MRRF mRNA CTD PMID:25629700 formaldehyde decreases expression ISO RGD:1314201 6480464 Formaldehyde results in decreased expression of MRRF mRNA CTD PMID:23649840 hydralazine multiple interactions ISO RGD:1314201 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of MRRF mRNA CTD PMID:17183730 ozone multiple interactions ISO RGD:1314201 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of MRRF mRNA more ... CTD PMID:32699268 p-toluidine decreases expression EXP 6480464 4-toluidine results in decreased expression of MRRF mRNA CTD PMID:27638505 pirinixic acid increases expression ISO RGD:1314202 6480464 pirinixic acid results in increased expression of MRRF mRNA CTD PMID:23811191 propiconazole increases expression ISO RGD:1314202 6480464 propiconazole results in increased expression of MRRF mRNA CTD PMID:21278054 SB 431542 multiple interactions ISO RGD:1314201 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of MRRF mRNA CTD PMID:27188386 sodium arsenite decreases expression ISO RGD:1314201 6480464 sodium arsenite results in decreased expression of MRRF mRNA CTD PMID:28595984 Soman decreases expression EXP 6480464 Soman results in decreased expression of MRRF mRNA CTD PMID:19281266 thapsigargin multiple interactions ISO RGD:1314201 6480464 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of MRRF mRNA] more ... CTD PMID:19442820 thapsigargin increases expression ISO RGD:1314201 6480464 Thapsigargin results in increased expression of MRRF mRNA CTD PMID:22378314 trans-caffeic acid multiple interactions ISO RGD:1314201 6480464 caffeic acid promotes the reaction [Thapsigargin results in decreased expression of MRRF mRNA] CTD PMID:19442820 tunicamycin increases expression ISO RGD:1314201 6480464 Tunicamycin results in increased expression of MRRF mRNA CTD PMID:22378314 valproic acid multiple interactions ISO RGD:1314201 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of MRRF mRNA more ... CTD PMID:17183730 , PMID:27188386 valproic acid affects expression ISO RGD:1314202 6480464 Valproic Acid affects the expression of MRRF mRNA CTD PMID:17963808 valproic acid decreases methylation ISO RGD:1314201 6480464 Valproic Acid results in decreased methylation of MRRF gene CTD PMID:29154799 valproic acid increases expression ISO RGD:1314201 6480464 Valproic Acid results in increased expression of MRRF mRNA CTD PMID:26272509 vorinostat increases expression ISO RGD:1314201 6480464 vorinostat results in increased expression of MRRF mRNA CTD PMID:27188386
References
Additional References at PubMed
Genomics
QTLs in Region (Rnor_6.0)
631679 Cm10 Cardiac mass QTL 10 7.34 0.0001 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 3 1 25786001 Rat 70202 Alc19 Alcohol consumption QTL 19 2.5 drinking behavior trait (VT:0001422) ethanol intake volume to total fluid intake volume ratio (CMO:0001591) 3 1 28136884 Rat 631545 Bp85 Blood pressure QTL 85 3.1 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 3 1 28500807 Rat 61468 Bp15 Blood pressure QTL 15 4.4 blood pressure trait (VT:0000183) diastolic blood pressure (CMO:0000005) 3 1 28500807 Rat 61468 Bp15 Blood pressure QTL 15 4.4 blood pressure trait (VT:0000183) systolic blood pressure (CMO:0000004) 3 1 28500807 Rat 61468 Bp15 Blood pressure QTL 15 4.4 blood pressure trait (VT:0000183) pulse pressure (CMO:0000292) 3 1 28500807 Rat 631831 Alc8 Alcohol consumption QTL 8 2.7 consumption behavior trait (VT:0002069) calculated ethanol drink intake rate (CMO:0001615) 3 1 32972944 Rat 4889966 Bss95 Bone structure and strength QTL 95 4.4 tibia area (VT:1000281) tibia-fibula cross-sectional area (CMO:0001718) 3 1 37891710 Rat 2312664 Scl62 Serum cholesterol level QTL 62 0.05 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 3 1 39773425 Rat 2290452 Scl56 Serum cholesterol level QTL 56 2.26 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 3 1 95176874 Rat 1298526 Arunc3 Aerobic running capacity QTL 3 2.2 exercise endurance trait (VT:0002332) maximum distance run on treadmill (CMO:0001406) 3 2631421 33477544 Rat 10401810 Kidm53 Kidney mass QTL 53 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 3 2631421 48562146 Rat 70203 Gcr2 Gastric cancer resistance QTL 2 2.6 stomach morphology trait (VT:0000470) stomach tumor susceptibility score (CMO:0002043) 3 3285929 28136884 Rat 1358357 Srcrtb1 Stress Responsive Cort Basal QTL 1 6.36 0.002 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 3 3285929 28136884 Rat 8693641 Alc30 Alcohol consumption QTL 30 2 0.739 drinking behavior trait (VT:0001422) calculated ethanol drink intake rate (CMO:0001615) 3 5654639 25105730 Rat 1558654 Bw56 Body weight QTL 56 4.5 0.0000171 body mass (VT:0001259) body weight (CMO:0000012) 3 6000748 34394365 Rat 6893355 Bw101 Body weight QTL 101 0.4 0.38 body mass (VT:0001259) body weight (CMO:0000012) 3 6000748 34394365 Rat 6893363 Bw105 Body weight QTL 105 2.6 0.0036 body mass (VT:0001259) body weight (CMO:0000012) 3 6000748 34394365 Rat 70191 BpQTLcluster4 Blood pressure QTL cluster 4 3 arterial blood pressure trait (VT:2000000) absolute change in mean arterial blood pressure (CMO:0000533) 3 6000748 51687917 Rat 70191 BpQTLcluster4 Blood pressure QTL cluster 4 3 arterial blood pressure trait (VT:2000000) absolute change in systolic blood pressure (CMO:0000607) 3 6000748 51687917 Rat 1558647 Cm46 Cardiac mass QTL 46 5.4 0.0000055 heart mass (VT:0007028) heart wet weight (CMO:0000069) 3 6000866 34394121 Rat 1558650 Cm48 Cardiac mass QTL 48 4 0.0001 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 3 6000866 34394121 Rat 1558657 Cm43 Cardiac mass QTL 43 6.6 0.0000000293 heart mass (VT:0007028) heart wet weight (CMO:0000069) 3 6000866 34394121 Rat 1358905 Hrtrt17 Heart rate QTL 17 5.9 0.000014 heart pumping trait (VT:2000009) heart rate (CMO:0000002) 3 10094081 93415837 Rat 2298542 Neuinf11 Neuroinflammation QTL 11 3.9 nervous system integrity trait (VT:0010566) spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126) 3 10119318 79772001 Rat 1358885 Bp251 Blood pressure QTL 251 3.8 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 3 10639528 127023997 Rat 1358888 Bp264 Blood pressure QTL 264 4.43 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 3 10639528 127023997 Rat 634306 Bp140 Blood pressure QTL 140 3.3 0.0013 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 3 13126914 36600143 Rat 634306 Bp140 Blood pressure QTL 140 3.3 0.0013 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 3 13126914 36600143 Rat 634306 Bp140 Blood pressure QTL 140 3.3 0.0013 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 3 13126914 36600143 Rat 634306 Bp140 Blood pressure QTL 140 3.3 0.0013 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 3 13126914 36600143 Rat 634306 Bp140 Blood pressure QTL 140 3.3 0.0013 arterial blood pressure trait (VT:2000000) heart rate (CMO:0000002) 3 13126914 36600143 Rat 634306 Bp140 Blood pressure QTL 140 3.3 0.0013 arterial blood pressure trait (VT:2000000) heart rate (CMO:0000002) 3 13126914 36600143 Rat 634306 Bp140 Blood pressure QTL 140 3.3 0.0013 arterial blood pressure trait (VT:2000000) body weight (CMO:0000012) 3 13126914 36600143 Rat 634306 Bp140 Blood pressure QTL 140 3.3 0.0013 arterial blood pressure trait (VT:2000000) body weight (CMO:0000012) 3 13126914 36600143 Rat 631568 Bp92 Blood pressure QTL 92 2.2 0.005 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 3 13126914 41510346 Rat 2325840 Bp345 Blood pressure QTL 345 0.001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 3 14090411 29084626 Rat 731172 Bp151 Blood pressure QTL 151 0.04 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 3 14090411 48562146 Rat 12879849 Bw180 Body weight QTL 180 0.037 body mass (VT:0001259) body weight (CMO:0000012) 3 14090411 48562146 Rat 12879850 Cm91 Cardiac mass QTL 91 0.001 heart mass (VT:0007028) heart wet weight to body weight ratio (CMO:0002408) 3 14090411 48562146 Rat 12879851 Cm92 Cardiac mass QTL 92 0.001 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 3 14090411 48562146 Rat 12879852 Cm93 Cardiac mass QTL 93 0.001 heart right ventricle mass (VT:0007033) heart right ventricle weight to body weight ratio (CMO:0000914) 3 14090411 48562146 Rat 12879853 Am5 Aortic mass QTL 5 0.001 aorta mass (VT:0002845) aorta weight to aorta length to body weight ratio (CMO:0002722) 3 14090411 48562146 Rat 12879854 Kidm63 Kidney mass QTL 63 0.001 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 3 14090411 48562146 Rat