Mrrf (mitochondrial ribosome recycling factor)

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Gene: Mrrf (mitochondrial ribosome recycling factor) Rattus norvegicus

Analyze

Symbol:

Mrrf

Name:

mitochondrial ribosome recycling factor

RGD ID:

1305897

Description:

Predicted to have ribosomal large subunit binding activity. Predicted to be involved in ribosome disassembly and translation. Predicted to localize to mitochondrion. Orthologous to human MRRF (mitochondrial ribosome recycling factor); INTERACTS WITH 2,4,6-trinitrotoluene; acrylamide; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

LOC311903; MGC93722; ribosome-recycling factor, mitochondrial; ribosome-releasing factor, mitochondrial; RRF

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	3	15,463,884 - 15,520,621 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	15,463,953 - 15,520,618 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	20,773,131 - 20,829,833 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	15,247,054 - 15,303,722 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	3	15,143,425 - 15,200,091 (+)	NCBI
Celera	3	14,199,058 - 14,255,750 (+)	NCBI		Celera
Cytogenetic Map	3	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,6-trinitrotoluene (EXP)

acrolein (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

cis-caffeic acid (ISO)

dorsomorphin (ISO)

folic acid (ISO)

formaldehyde (ISO)

hydralazine (ISO)

ozone (ISO)

p-toluidine (EXP)

pirinixic acid (ISO)

propiconazole (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

Soman (EXP)

thapsigargin (ISO)

trans-caffeic acid (ISO)

tunicamycin (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ribosome disassembly (ISO)

translation (IBA)

Cellular Component

mitochondrion (IBA)

Molecular Function

protein binding (ISO)

ribosomal large subunit binding (IBA)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	MGD data from the GO Consortium
3.	RGD automated data pipeline
4.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:18614015	PMID:19716793

Genomics

Comparative Map Data

Mrrf
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	3	15,463,884 - 15,520,621 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	15,463,953 - 15,520,618 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	20,773,131 - 20,829,833 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	15,247,054 - 15,303,722 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	3	15,143,425 - 15,200,091 (+)	NCBI
Celera	3	14,199,058 - 14,255,750 (+)	NCBI		Celera
Cytogenetic Map	3	p11	NCBI

MRRF
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	9	122,264,603 - 122,331,337 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	9	122,264,882 - 122,331,337 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	9	125,026,882 - 125,085,743 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	124,066,968 - 124,125,564 (+)	NCBI	NCBI36		hg18	NCBI36
Celera	9	95,675,208 - 95,734,069 (+)	NCBI
Cytogenetic Map	9	q33.2	NCBI
HuRef	9	94,641,577 - 94,700,513 (+)	NCBI		HuRef
CHM1_1	9	125,174,951 - 125,233,831 (+)	NCBI		CHM1_1

Mrrf
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	36,025,672 - 36,080,296 (+)	NCBI	GRCm39		mm39
GRCm38	2	36,135,660 - 36,190,284 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	36,136,389 - 36,190,647 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	35,991,918 - 36,045,804 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	2	35,992,187 - 36,045,390 (+)	NCBI			mm8
Celera	2	35,840,067 - 35,880,949 (+)	NCBI		Celera
Cytogenetic Map	2	B	NCBI

Mrrf
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955419	5,750,344 - 5,800,723 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955419	5,750,344 - 5,800,723 (-)	NCBI	ChiLan1.0	ChiLan1.0

MRRF
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	9	121,730,540 - 121,792,006 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	121,730,783 - 121,790,157 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	9	93,389,726 - 93,448,596 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

MRRF
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	9	60,258,977 - 60,314,864 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	9	60,256,728 - 60,314,561 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Mrrf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936487	10,649,395 - 10,700,211 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MRRF
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	262,353,032 - 262,418,243 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	262,355,994 - 262,416,116 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	294,656,012 - 294,713,765 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MRRF
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	17,266,365 - 17,330,768 (-)	NCBI
ChlSab1.1 Ensembl	12	17,263,882 - 17,330,341 (-)	Ensembl

Mrrf
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624760	12,974,428 - 13,032,016 (-)	NCBI

Position Markers

RH132526

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	3	p11	UniSTS

BQ205974

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	3	15,482,493 - 15,482,665	NCBI	Rnor6.0
Rnor_5.0	3	20,791,705 - 20,791,877	UniSTS	Rnor5.0
RGSC_v3.4	3	15,265,594 - 15,265,766	UniSTS	RGSC3.4
Celera	3	14,217,598 - 14,217,770	UniSTS
Cytogenetic Map	3	p11	UniSTS
RH 3.4 Map	3	212.02	UniSTS

UniSTS:234165

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	2	9,282,585 - 9,282,813	NCBI	Rnor6.0
Rnor_5.0	2	9,162,877 - 9,163,105	UniSTS	Rnor5.0
Celera	2	8,052,144 - 8,052,372	UniSTS
Cytogenetic Map	2	q11	UniSTS
Cytogenetic Map	3	p11	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631679	Cm10	Cardiac mass QTL 10	7.34	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	1	25786001	Rat
70202	Alc19	Alcohol consumption QTL 19	2.5		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	3	1	28136884	Rat
631545	Bp85	Blood pressure QTL 85	3.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	28500807	Rat
61468	Bp15	Blood pressure QTL 15	4.4		blood pressure trait (VT:0000183)	diastolic blood pressure (CMO:0000005)	3	1	28500807	Rat
61468	Bp15	Blood pressure QTL 15	4.4		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	3	1	28500807	Rat
61468	Bp15	Blood pressure QTL 15	4.4		blood pressure trait (VT:0000183)	pulse pressure (CMO:0000292)	3	1	28500807	Rat
631831	Alc8	Alcohol consumption QTL 8	2.7		consumption behavior trait (VT:0002069)	calculated ethanol drink intake rate (CMO:0001615)	3	1	32972944	Rat
4889966	Bss95	Bone structure and strength QTL 95	4.4		tibia area (VT:1000281)	tibia-fibula cross-sectional area (CMO:0001718)	3	1	37891710	Rat
2312664	Scl62	Serum cholesterol level QTL 62		0.05	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	1	39773425	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	95176874	Rat
1298526	Arunc3	Aerobic running capacity QTL 3	2.2		exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	2631421	33477544	Rat
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	2631421	48562146	Rat
70203	Gcr2	Gastric cancer resistance QTL 2	2.6		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	3	3285929	28136884	Rat
1358357	Srcrtb1	Stress Responsive Cort Basal QTL 1	6.36	0.002	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	3285929	28136884	Rat
8693641	Alc30	Alcohol consumption QTL 30	2	0.739	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	3	5654639	25105730	Rat
1558654	Bw56	Body weight QTL 56	4.5	0.0000171	body mass (VT:0001259)	body weight (CMO:0000012)	3	6000748	34394365	Rat
6893355	Bw101	Body weight QTL 101	0.4	0.38	body mass (VT:0001259)	body weight (CMO:0000012)	3	6000748	34394365	Rat
6893363	Bw105	Body weight QTL 105	2.6	0.0036	body mass (VT:0001259)	body weight (CMO:0000012)	3	6000748	34394365	Rat
70191	BpQTLcluster4	Blood pressure QTL cluster 4	3		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	3	6000748	51687917	Rat
70191	BpQTLcluster4	Blood pressure QTL cluster 4	3		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	3	6000748	51687917	Rat
1558647	Cm46	Cardiac mass QTL 46	5.4	0.0000055	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	6000866	34394121	Rat
1558650	Cm48	Cardiac mass QTL 48	4	0.0001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	3	6000866	34394121	Rat
1558657	Cm43	Cardiac mass QTL 43	6.6	0.0000000293	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	6000866	34394121	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	10094081	93415837	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	10119318	79772001	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	10639528	127023997	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	10639528	127023997	Rat
634306	Bp140	Blood pressure QTL 140	3.3	0.0013	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	13126914	36600143	Rat
634306	Bp140	Blood pressure QTL 140	3.3	0.0013	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	13126914	36600143	Rat
634306	Bp140	Blood pressure QTL 140	3.3	0.0013	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	3	13126914	36600143	Rat
634306	Bp140	Blood pressure QTL 140	3.3	0.0013	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	3	13126914	36600143	Rat
634306	Bp140	Blood pressure QTL 140	3.3	0.0013	arterial blood pressure trait (VT:2000000)	heart rate (CMO:0000002)	3	13126914	36600143	Rat
634306	Bp140	Blood pressure QTL 140	3.3	0.0013	arterial blood pressure trait (VT:2000000)	heart rate (CMO:0000002)	3	13126914	36600143	Rat
634306	Bp140	Blood pressure QTL 140	3.3	0.0013	arterial blood pressure trait (VT:2000000)	body weight (CMO:0000012)	3	13126914	36600143	Rat
634306	Bp140	Blood pressure QTL 140	3.3	0.0013	arterial blood pressure trait (VT:2000000)	body weight (CMO:0000012)	3	13126914	36600143	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	13126914	41510346	Rat
2325840	Bp345	Blood pressure QTL 345		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14090411	29084626	Rat
731172	Bp151	Blood pressure QTL 151		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14090411	48562146	Rat
12879849	Bw180	Body weight QTL 180		0.037	body mass (VT:0001259)	body weight (CMO:0000012)	3	14090411	48562146	Rat
12879850	Cm91	Cardiac mass QTL 91		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	14090411	48562146	Rat
12879851	Cm92	Cardiac mass QTL 92		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	14090411	48562146	Rat
12879852	Cm93	Cardiac mass QTL 93		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	14090411	48562146	Rat
12879853	Am5	Aortic mass QTL 5		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	14090411	48562146	Rat
12879854	Kidm63	Kidney mass QTL 63		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	14090411	48562146	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	460
Count of miRNA genes:	234
Interacting mature miRNAs:	300
Transcripts:	ENSRNOT00000033047
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	35	28	20	10	20	1	3	66	31	38	11	1
Low		8	29	21	9	21	7	8	8	4	3		7
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001008354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234069	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AABR07072856	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01020940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC106602	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC085779	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220851	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000033047 ⟹ ENSRNOP00000038041

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	15,463,953 - 15,520,618 (+)	Ensembl

RefSeq Acc Id:

NM_001008354 ⟹ NP_001008355

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	15,463,953 - 15,520,621 (+)	NCBI
Rnor_5.0	3	20,773,131 - 20,829,833 (+)	NCBI
RGSC_v3.4	3	15,247,054 - 15,303,722 (+)	RGD
Celera	3	14,199,058 - 14,255,750 (+)	RGD

Sequence:

show sequence

CTATAATCCCGGCTGTAGCTGTGGCTGCTTCTGAGGATTCTCTCCCGTCATGGCCTTGGGAATA
AGATGCTTTCGCCTACTACATCCTGCCTTTAGCAGCTACCTGGCTGATTTGAGCAGACCTGTTT
CAGAAGTTCCCATGAAGACAGTGCGAGGAAGACAACGTGACCATATACAGTACTCAGCCCACCC
AGCAGTGCCAGTTCGCCAGTTTGCAACCAAGAAGGCCAAAGCCAAAGGGAAAGGACAGCCCCAG
GCCAGAGTGAACATTAACACTGCCTTGGTTGAGGACATAATCAGTTTGGAAGAGGTGGATGAAG
ACATGAAATCTGTGATGGAAGCACTTAAAGATAATTTCAATAAGACTCTCAACATAAGGACTGC
ACCAGGATCCCTTGATCATATTACTGTGGTAACTGCTGATGGGAAGCTTGCTCTAAACCAGATT
GGCCAGATCTCCATGAAGTCGCCACAGTTGATTCTGGTGAATATGGCCAGCTTCCCAGAGTGTA
CAGCTGCAGCTATCAAGGCTATAAGAGAAAGTGGAATGAATCTGAACCCAGAAGTGGAAGGAAC
ACTAATTCGGGTACCCATTCCTAAAGTAACCAGGGAACACAGAGAAATGCTGGTGAAACTGGCC
AAACAGAACACCAACAAAGCCAAAGAAAATTTACGGAAGGTTCGCACTAATGCAATGAATAAAC
TGAAGAAGTCAAAGGACAAAACCTCAGAGGACACCATTAGGCTCATCGAGAAGCAGATCAGCCA
AATGGCAGACGACACGGTGGCGGAGCTGGACCGGCATCTGGCAGCAAAGACCAAAGAACTTCTT
GGATGAAAGTCAGCAGTCACAGCCGAGCACCAGTGTCTGCTCATGCAGTGGGTGGCAAGCGTGT
GCGCCCACTGCCCTGACCATCCATCATGCAGTGGGTGGCAAGCGTGTGCGCCCACTGCCCTGAC
CATCCATGGGAGGCTGACACTGCTGCTCCTCCGTCAGCCACTCAGCTTCCTGTTGGGATGCTCA
GACGTATGGAATCTCTTCCTCGTTTCCTTGCTCTGCTCAGAATCTCCTGGTGTGAAGGCCCTCA
GAGAATGTCTCCTGGTGTGAAGGCCCTCAGAGAATGTCTCCTGGTGTGAAGGCAGAGGACCTTT
ACTCTGGCAGTGACCATGACTGTGGTGTCATGGCAAGACTAGGGCCACCGTCAGGCTTAGCAGC
TCCTCTCTTCAACATAGGAGCCTCCTTTCAAACTGTGAATCATCCCCTGCCCTTGTGTTAAACT
CATTTGGATTAACGTGGACCTTCAGTCCAACTGCTAATGATCAAGCCTAAATAAATTGGAAAAT
AACAACCACAGAGGAAAGAGAGAGAGGTTTGGATGGAAAGCCCCAGTGCTTGTTTATAAAGCAA
CCAAGAGCAATGCTTTTGCCTCTAGGTTGTCGTCCCACATGCTGTTCTATGTGGACCGAGCTTC
CGCTCCTAACAACCAGCCCTGTTTACTGTGGTCAGTTGCTCCCTCTGGGCAGTCTCTCTGCCTC
CAGATTAGGCCCCAGTTTTGGCTGGGCTACTCTTATTTAAACCTCTGTTTTTCTTTTCTGTTAG
TCTATATCTGGAGAAAAATTACCAGAGAGAATGACACAGTAACACTTGAAGTTGTCCATGTATT
TATGCTGTGAGATTGTTAGCTGCTCTCCAAATGTTTTTCTTCTCTCCGTCACTCCACTCTTGTC
TCTGTCAACATTTATTTGGTAATGAGCTACTATTTCTCCTGATAGACAGGTCCTTTGTTGTGAC
TGTCTTTTTCTTCTTCTTTTCATTGCTGTTTGCCGTGCCATCGCTTTCGTGTAGAGGTCAGGTC
AGACAGCTCCCAGGAGTCAGCTCTCACCTTGTGGGATGGACCCAGATCCTCCCTACCAAGCACC
TTTGTCTGCTGAGTCATCTCACTTGCTGCGCTGTGGCTTTCAGTGCCAAGTTAAGTCAGTCATT
TTTCCCTTCCCCTGCAGACATTCCTTCATTCATTTAATTATAATAAAGCTATATTTAGGCATTA
TTTGTAATCACAAAACGAGACAGATACCTGCACTTACAAATATGGAAACTGGCACGGCAGTGTT
AGGTACTGAGTCCTCCAGACAGTGGAGTGGGAAAGTGGTGGGACATTTTATTTTCCTTTCTTTT
TCTGATAACAAGGTCACTCTACATAGCCCTAACTGTCCTGGAGCTCACTCTGTATACCAACTGT
GCTGGCCTTGAACTCGGTACTCCTGCCTCAGCTTCTCGAGTGCTTAGTTTAAAGGTGTGGGCCA
CTGCCCAGCTAGGGGCATTTCCATTGTACAAGATGCAGTTTCTCAAGCCCTGTCATACAGCCAG
CAAGCGGCTAGGCAGAGAGAAAAGTTGTAGGCTTGATTCCAGAGTCTGTTCTTTCCACCGAACA
GAGTGAGAGGCGAATGACCATTTCCACCACATACCGAGCGGTTCTCCAGTGCAGACCAACCAGG
TATCCGGTATGGAGTCAATTCTGAGACATAACTACCTGTGGAGTCTGGGGTTCTGCACTCCGCC
CTGAAAAATGCCCTATTTTTCTGACAACAATCGCAAGTCTGGACCACACAAACCTAGTTCCCGG
CCCCCCCCTTTGATCTGGTTAATCAGCGGATGATGCTCAGGGCTTGGGAGGTAGGTTTTCTGGC
TTTTTATAAAGCATGCTCTGAGGCGTACAGATGAACACGATTCAGGGGATTAGGGGAGGTGGGA
TACTGGGAAGCAGGAATATGCTCCGAGGCACCCTGGGTGGCCACATTCCCAGCACTGCCAGATT
GTCCAACCTGAAGAAGCCACTGCCACCTGCTGTCCTGTCAGGACGCAGTGGGCACCAGCTGTTT
CTCCCGTGCCCTATTATGTGCTAGAACACAGAGGCTGCTGGGCTGTGACTGCTGGCTTTGAGCA
GTGCCACTACACTGAACTGAGTGGCCCTCACAGTGCCCCAAGCAGGAAGGTCTGTTCGAGGTCT
AGGTGGTGAGATGTGGCTCAAGGAACCTGCGCTAGCTACTAAAGCTGCTGCTGCTGCTGCCTCT
GCCCACACTAGTGGGACCTGCTGGGAAATAGCCAGTGCGAATTAGGACTAGGCCAGGGATGAAA
GGAACTAACATGCCCTCCCACCCCATTTACTTACCCTCAAAGCCAGAGACAAATGGGAAGTTAG
GCTGCCAGGGGAGAGCTTCTGGAGCCACAAGGTGGAGGCTTTGCCAGGGTTCAGTTCTGCGAGT
GACCAGAATTCTCGCTGCAAATGTGCTGCTCAAAGATGCAGGATTTTTTTTTAATAAACAGAGG
AAATGATAAATTATGTTGTAACTCCACTCCAAAGGCATTTGGTTCTTAACAGCCAAATCCTCTG
TAGTCTTTAAATAAACAAAACTTATTTGGTGAACAGACGGGGGTGGGGAGGGATGAAAGATTTT
CAGTACTTGGGTTCCACATGTCAACAATTTCTCTCCTGTGTGTATGTTGGCCAAAGCCATATAT
CATGATAAATGAATAAAGGAAAGCCCTGAGCCCAGGGCGGTGAGACAGCTCAGCAAAAAAAAAA
AAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006234069 ⟹ XP_006234131

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	15,463,884 - 15,520,621 (+)	NCBI
Rnor_5.0	3	20,773,131 - 20,829,833 (+)	NCBI

Sequence:

show sequence

GCGCCGCCGCGCCAGCCCGTGACGTCATGACGCCCGCACCTCCGCCTCCGCTGTCCCGCGTGTG
TTTCTCTATAATCCCGGCTGTAGCTGTGGCTGCTTCTGAGGATTCTCTCCCGTCATGGCCTTGG
GAATAAGATGCTTTCGCCTACTACATCCTGCCTTTAGCAGCTACCTGGCTGATTTGAGCAGACC
TGTTTCAGAAGTTCCCATGAAGACAGTGCGAGGAAGACAACGTGACCATATACAGTACTCAGCC
CACCCAGCAGTGCCAGTTCGCCAGTTTGCAACCAAGAAGGCCAAAGGATCCCTTGATCATATTA
CTGTGGTAACTGCTGATGGGAAGCTTGCTCTAAACCAGATTGGCCAGATCTCCATGAAGTCGCC
ACAGTTGATTCTGGTGAATATGGCCAGCTTCCCAGAGTGTACAGCTGCAGCTATCAAGGCTATA
AGAGAAAGTGGAATGAATCTGAACCCAGAAGTGGAAGGAACACTAATTCGGGTACCCATTCCTA
AAGTAACCAGGGAACACAGAGAAATGCTGGTGAAACTGGCCAAACAGAACACCAACAAAGCCAA
AGAAAATTTACGGAAGGTTCGCACTAATGCAATGAATAAACTGAAGAAGTCAAAGGACAAAACC
TCAGAGGACACCATTAGGCTCATCGAGAAGCAGATCAGCCAAATGGCAGACGACACGGTGGCGG
AGCTGGACCGGCATCTGGCAGCAAAGACCAAAGAACTTCTTGGATGAAAGTCAGCAGTCACAGC
CGAGCACCAGTGTCTGCTCATGCAGTGGGTGGCAAGCGTGTGCGCCCACTGCCCTGACCATCCA
TCATGCAGTGGGTGGCAAGCGTGTGCGCCCACTGCCCTGACCATCCATGGGAGGCTGACACTGC
TGCTCCTCCGTCAGCCACTCAGCTTCCTGTTGGGATGCTCAGACGTATGGAATCTCTTCCTCGT
TTCCTTGCTCTGCTCAGAATCTCCTGGTGTGAAGGCCCTCAGAGAATGTCTCCTGGTGTGAAGG
CCCTCAGAGAATGTCTCCTGGTGTGAAGGCAGAGGACCTTTACTCTGGCAGTGACCATGACTGT
GGTGTCATGGCAAGACTAGGGCCACCGTCAGGCTTAGCAGCTCCTCTCTTCAACATAGGAGCCT
CCTTTCAAACTGTGAATCATCCCCTGCCCTTGTGTTAAACTCATTTGGATTAACGTGGACCTTC
AGTCCAACTGCTAATGATCAAGCCTAAATAAATTGGAAAATAACAACCACAGAGGAAAGAGAGA
GAGGTTTGGATGGAAAGCCCCAGTGCTTGTTTATAAAGCAACCAAGAGCAATGCTTTTGCCTCT
AGGTTGTCGTCCCACATGCTGTTCTATGTGGACCGAGCTTCCGCTCCTAACAACCAGCCCTGTT
TACTGTGGTCAGTTGCTCCCTCTGGGCAGTCTCTCTGCCTCCAGATTAGGCCCCAGTTTTGGCT
GGGCTACTCTTATTTAAACCTCTGTTTTTCTTTTCTGTTAGTCTATATCTGGAGAAAAATTACC
AGAGAGAATGACACAGTAACACTTGAAGTTGTCCATGTATTTATGCTGTGAGATTGTTAGCTGC
TCTCCAAATGTTTTTCTTCTCTCCGTCACTCCACTCTTGTCTCTGTCAACATTTATTTGGTAAT
GAGCTACTATTTCTCCTGATAGACAGGTCCTTTGTTGTGACTGTCTTTTTCTTCTTCTTTTCAT
TGCTGTTTGCCGTGCCATCGCTTTCGTGTAGAGGTCAGGTCAGACAGCTCCCAGGAGTCAGCTC
TCACCTTGTGGGATGGACCCAGATCCTCCCTACCAAGCACCTTTGTCTGCTGAGTCATCTCACT
TGCTGCGCTGTGGCTTTCAGTGCCAAGTTAAGTCAGTCATTTTTCCCTTCCCCTGCAGACATTC
CTTCATTCATTTAATTATAATAAAGCTATATTTAGGCATTATTTGTAATCACAAAACGAGACAG
ATACCTGCACTTACAAATATGGAAACTGGCACGGCAGTGTTAGGTACTGAGTCCTCCAGACAGT
GGAGTGGGAAAGTGGTGGGACATTTTATTTTCCTTTCTTTTTCTGATAACAAGGTCACTCTACA
TAGCCCTAACTGTCCTGGAGCTCACTCTGTATACCAACTGTGCTGGCCTTGAACTCGGTACTCC
TGCCTCAGCTTCTCGAGTGCTTAGTTTAAAGGTGTGGGCCACTGCCCAGCTAGGGGCATTTCCA
TTGTACAAGATGCAGTTTCTCAAGCCCTGTCATACAGCCAGCAAGCGGCTAGGCAGAGAGAAAA
GTTGTAGGCTTGATTCCAGAGTCTGTTCTTTCCACCGAACAGAGTGAGAGGCGAATGACCATTT
CCACCACATACCGAGCGGTTCTCCAGTGCAGACCAACCAGGTATCCGGTATGGAGTCAATTCTG
AGACATAACTACCTGTGGAGTCTGGGGTTCTGCACTCCGCCCTGAAAAATGCCCTATTTTTCTG
ACAACAATCGCAAGTCTGGACCACACAAACCTAGTTCCCGGCCCCCCCCTTTGATCTGGTTAAT
CAGCGGATGATGCTCAGGGCTTGGGAGGTAGGTTTTCTGGCTTTTTATAAAGCATGCTCTGAGG
CGTACAGATGAACACGATTCAGGGGATTAGGGGAGGTGGGATACTGGGAAGCAGGAATATGCTC
CGAGGCACCCTGGGTGGCCACATTCCCAGCACTGCCAGATTGTCCAACCTGAAGAAGCCACTGC
CACCTGCTGTCCTGTCAGGACGCAGTGGGCACCAGCTGTTTCTCCCGTGCCCTATTATGTGCTA
GAACACAGAGGCTGCTGGGCTGTGACTGCTGGCTTTGAGCAGTGCCACTACACTGAACTGAGTG
GCCCTCACAGTGCCCCAAGCAGGAAGGTCTGTTCGAGGTCTAGGTGGTGAGATGTGGCTCAAGG
AACCTGCGCTAGCTACTAAAGCTGCTGCTGCTGCTGCCTCTGCCCACACTAGTGGGACCTGCTG
GGAAATAGCCAGTGCGAATTAGGACTAGGCCAGGGATGAAAGGAACTAACATGCCCTCCCACCC
CATTTACTTACCCTCAAAGCCAGAGACAAATGGGAAGTTAGGCTGCCAGGGGAGAGCTTCTGGA
GCCACAAGGTGGAGGCTTTGCCAGGGTTCAGTTCTGCGAGTGACCAGAATTCTCGCTGCAAATG
TGCTGCTCAAAGATGCAGGATTTTTTTTTAATAAACAGAGGAAATGATAAATTATGTTGTAACT
CCACTCCAAAGGCATTTGGTTCTTAACAGCCAAATCCTCTGTAGTCTTTAAATAAACAAAACTT
ATTTGGTGAACAGACGGGGGTGGGGAGGGATGAAAGATTTTCAGTACTTGGGTTCCACATGTCA
ACAATTTCTCTCCTGTGTGTATGTTGGCCAAAGCCATATATCATGATAAATGAATAAAGGAAAG
CCCTGAGCCCAGGGCGGTGAGACAGCTCAGCAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001008355	(Get FASTA)	NCBI Sequence Viewer
	XP_006234131	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH85779	(Get FASTA)	NCBI Sequence Viewer
	Q5RKI9	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001008355 ⟸ NM_001008354
- Peptide Label:	precursor
- UniProtKB:	Q5RKI9 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MALGIRCFRLLHPAFSSYLADLSRPVSEVPMKTVRGRQRDHIQYSAHPAVPVRQFATKKAKAKG KGQPQARVNINTALVEDIISLEEVDEDMKSVMEALKDNFNKTLNIRTAPGSLDHITVVTADGKL ALNQIGQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRVPIPKVTREHREM LVKLAKQNTNKAKENLRKVRTNAMNKLKKSKDKTSEDTIRLIEKQISQMADDTVAELDRHLAAK TKELLG hide sequence

RefSeq Acc Id:

XP_006234131 ⟸ XM_006234069

- Peptide Label:

isoform X1

- Sequence:

show sequence

MALGIRCFRLLHPAFSSYLADLSRPVSEVPMKTVRGRQRDHIQYSAHPAVPVRQFATKKAKGSL
DHITVVTADGKLALNQIGQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRV
PIPKVTREHREMLVKLAKQNTNKAKENLRKVRTNAMNKLKKSKDKTSEDTIRLIEKQISQMADD
TVAELDRHLAAKTKELLG

hide sequence

RefSeq Acc Id:

ENSRNOP00000038041 ⟸ ENSRNOT00000033047

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692024

Promoter ID:

EPDNEW_R2548

Type:

multiple initiation site

Name:

Mrrf_1

Description:

mitochondrial ribosome recycling factor

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	15,463,919 - 15,463,979	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305897	AgrOrtholog
Ensembl Genes	ENSRNOG00000025997	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000038041	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000033047	ENTREZGENE, UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7106905	IMAGE-MGC_LOAD
InterPro	Ribosome_recyc_fac	UniProtKB/Swiss-Prot
	Ribosome_recyc_fac_dom	UniProtKB/Swiss-Prot
	RRF_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:311903	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93722	IMAGE-MGC_LOAD
NCBI Gene	311903	ENTREZGENE
PANTHER	PTHR20982	UniProtKB/Swiss-Prot
Pfam	RRF	UniProtKB/Swiss-Prot
PhenoGen	Mrrf	PhenoGen
Superfamily-SCOP	SSF55194	UniProtKB/Swiss-Prot
UniGene	Rn.105234	ENTREZGENE
UniProt	Q5RKI9	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Mrrf	mitochondrial ribosome recycling factor	Mrrf_predicted	mitochondrial ribosome recycling factor (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Mrrf_predicted	mitochondrial ribosome recycling factor (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)