Advanced Search (OLGA)

Gene: Hs6st3 (heparan sulfate 6-O-sulfotransferase 3) Rattus norvegicus

Analyze

Symbol:

Hs6st3

Name:

heparan sulfate 6-O-sulfotransferase 3

RGD ID:

1305888

Description:

Predicted to enable heparan sulfate 6-sulfotransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Orthologous to human HS6ST3 (heparan sulfate 6-O-sulfotransferase 3); PARTICIPATES IN heparan sulfate biosynthetic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; acrylamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

heparan-sulfate 6-O-sulfotransferase 3; LOC306170; LOC364476; RGD1560050; similar to heparan sulfate 6-sulfotransferase 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	102,688,420 - 103,407,725 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	102,688,365 - 103,408,384 (+)	Ensembl				GRCr8
mRatBN7.2	15	96,281,502 - 97,000,804 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	96,281,646 - 97,000,462 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	100,187,141 - 100,922,721 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	101,319,502 - 102,029,799 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	98,248,330 - 98,971,892 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	104,448,479 - 105,254,540 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	104,448,600 - 105,254,214 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	108,635,603 - 108,663,069 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	15	107,871,035 - 107,871,884 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	104,157,904 - 104,914,126	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	95,121,926 - 95,826,748 (+)	NCBI		Celera
Cytogenetic Map	15	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Anal Atresia, Hypospadias, and Penoscrotal Inversion (ISO)

holoprosencephaly 5 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-diaminodiphenylmethane (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

chlorpyrifos (ISO)

choline (ISO)

cisplatin (ISO)

copper atom (EXP)

copper(0) (EXP)

Cuprizon (EXP)

dioxygen (ISO)

dorsomorphin (ISO)

entinostat (ISO)

ethanol (ISO)

folic acid (ISO)

glyphosate (EXP,ISO)

L-methionine (ISO)

Lasiocarpine (ISO)

methotrexate (ISO)

N,N-diethyl-m-toluamide (EXP)

N-Nitrosopyrrolidine (ISO)

nickel atom (ISO)

O-methyleugenol (ISO)

paracetamol (EXP)

permethrin (EXP,ISO)

SB 431542 (ISO)

sunitinib (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

heparan sulfate proteoglycan biosynthetic process (IBA,IEA,ISO)

Cellular Component

Golgi apparatus (IEA,ISO)

membrane (IEA)

Molecular Function

heparan sulfate 6-sulfotransferase activity (IBA,IEA,ISO)

sulfotransferase activity (IEA)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

heparan sulfate biosynthetic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
2.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10644753	PMID:21873635	PMID:25761692

Genomics

Comparative Map Data

Hs6st3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	102,688,420 - 103,407,725 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	102,688,365 - 103,408,384 (+)	Ensembl				GRCr8
mRatBN7.2	15	96,281,502 - 97,000,804 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	96,281,646 - 97,000,462 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	100,187,141 - 100,922,721 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	101,319,502 - 102,029,799 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	98,248,330 - 98,971,892 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	104,448,479 - 105,254,540 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	104,448,600 - 105,254,214 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	108,635,603 - 108,663,069 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	15	107,871,035 - 107,871,884 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	104,157,904 - 104,914,126	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	95,121,926 - 95,826,748 (+)	NCBI		Celera
Cytogenetic Map	15	q24	NCBI

HS6ST3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	96,090,107 - 96,839,562 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	13	96,090,107 - 96,839,562 (+)	Ensembl			hg38	GRCh38
GRCh37	13	96,742,361 - 97,491,816 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	95,541,094 - 96,289,813 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	13	95,541,093 - 96,289,812	NCBI
Celera	13	77,590,616 - 78,339,250 (+)	NCBI		Celera
Cytogenetic Map	13	q32.1	NCBI
HuRef	13	77,340,282 - 78,088,949 (+)	NCBI		HuRef
CHM1_1	13	96,713,494 - 97,462,214 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	13	95,294,349 - 96,043,658 (+)	NCBI		T2T-CHM13v2.0

Hs6st3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	119,374,902 - 120,226,864 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	119,375,753 - 120,107,227 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	14	119,137,516 - 119,869,815 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	119,138,341 - 119,869,815 (+)	Ensembl			mm10	GRCm38
MGSCv37	14	119,537,487 - 120,269,037 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	14	118,273,483 - 119,004,997 (+)	NCBI		MGSCv36	mm8
Celera	14	117,692,032 - 118,432,138 (+)	NCBI		Celera
Cytogenetic Map	14	E4	NCBI
cM Map	14	62.67	NCBI

Hs6st3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955404	13,468,128 - 14,128,707 (-)	Ensembl
ChiLan1.0	NW_004955404	13,461,906 - 14,129,089 (-)	NCBI	ChiLan1.0	ChiLan1.0

HS6ST3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	14	97,612,103 - 98,354,539 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	13	96,671,258 - 97,023,269 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	13	77,256,399 - 77,998,022 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	13	96,414,415 - 97,150,741 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	13	96,414,409 - 97,148,398 (+)	Ensembl			panPan2	panpan1.1

HS6ST3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	22	47,257,641 - 47,265,143 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	22	47,117,757 - 47,259,351 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	22	46,415,114 - 47,045,651 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	22	47,059,742 - 47,690,994 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UMICH_Zoey_3.1	22	46,722,627 - 47,354,975 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	22	46,755,655 - 47,387,212 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	22	46,792,123 - 47,424,056 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Hs6st3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	182,140,408 - 182,794,486 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936472	13,163,842 - 13,811,708 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936472	13,157,669 - 13,811,747 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HS6ST3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	11	65,516,097 - 66,187,242 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	11	65,516,180 - 66,193,410 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	11	73,192,012 - 73,199,496 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HS6ST3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	3	74,840,589 - 75,576,397 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666046	31,277,947 - 32,026,474 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hs6st3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624879	2,678,482 - 3,402,590 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624879	2,678,403 - 3,408,630 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	213
Count of miRNA genes:	155
Interacting mature miRNAs:	169
Transcripts:	ENSRNOT00000057567, ENSRNOT00000071685
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1576315	Schws6	Schwannoma susceptibility QTL 6		0.0069	nervous system integrity trait (VT:0010566)	post-insult time of death (CMO:0002005)	15	60213984	105213984	Rat
1300144	Rf23	Renal function QTL 23	3.61		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	15	44806773	104695021	Rat
1549844	Bss7	Bone structure and strength QTL 7	6.4		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	15	82194914	108192169	Rat
2300326	Plaw1	Placental weight QTL 1	15	0.005	placenta mass (VT:0004257)	placenta wet weight (CMO:0002088)	15	74735564	106469153	Rat
1300118	Bp190	Blood pressure QTL 190	2.94		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	15	88677086	104695021	Rat
1358354	Srcrt5	Stress Responsive Cort QTL 5	3.38		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	15	82503470	108192169	Rat
70155	Gcs1	Gastric cancer susceptibility QTL1	3.8		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	15	82714037	106778197	Rat
1300120	Kidm7	Kidney mass QTL 7	3.55		kidney mass (VT:0002707)	left kidney wet weight to body weight ratio (CMO:0001954)	15	88677086	104695021	Rat
631655	Bp126	Blood pressure QTL 126	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	15	64571127	108192169	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	25285835	104695021	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	25285835	104695021	Rat
7411646	Foco21	Food consumption QTL 21	23.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	15	84278281	108192169	Rat
2298549	Neuinf12	Neuroinflammation QTL 12	3.5		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	15	61710951	106710951	Rat
1641889	Colcr6	Colorectal carcinoma resistance QTL 6	2.9	0.0126	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	15	83700787	108192169	Rat
2317050	Aia24	Adjuvant induced arthritis QTL 24	2.06		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	15	59257087	104257087	Rat
2313080	Bss65	Bone structure and strength QTL 65	3.9	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	15	67399137	108192169	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	25285835	104695021	Rat
2317055	Aia10	Adjuvant induced arthritis QTL 10	3.41		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	15	82194914	108192169	Rat

Markers in Region

D15Got92

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	15	103,020,841 - 103,021,133 (+)	Marker Load Pipeline
mRatBN7.2	15	96,613,931 - 96,614,225 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	104,867,143 - 104,867,434	NCBI	Rnor6.0
Rnor_5.0	15	108,273,038 - 108,273,329	UniSTS	Rnor5.0
RGSC_v3.4	15	104,507,981 - 104,508,273	RGD	RGSC3.4
RGSC_v3.4	15	104,507,982 - 104,508,273	UniSTS	RGSC3.4
Celera	15	95,452,591 - 95,452,882	UniSTS
RGSC_v3.1	15	104,523,762 - 104,524,053	RGD
RH 3.4 Map	15	688.3	UniSTS
RH 3.4 Map	15	688.3	RGD
RH 2.0 Map	15	587.0	RGD
Cytogenetic Map	15	q24	UniSTS

D15Got241

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	15	103,296,154 - 103,296,245 (+)	Marker Load Pipeline
mRatBN7.2	15	96,889,244 - 96,889,335 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	105,144,515 - 105,144,605	NCBI	Rnor6.0
Rnor_5.0	15	108,552,507 - 108,552,597	UniSTS	Rnor5.0
RGSC_v3.4	15	104,796,172 - 104,796,262	UniSTS	RGSC3.4
Celera	15	95,715,996 - 95,716,086	UniSTS
Cytogenetic Map	15	q24	UniSTS

BE101758

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	96,524,750 - 96,524,953 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	104,761,073 - 104,761,275	NCBI	Rnor6.0
Rnor_5.0	15	108,171,470 - 108,171,672	UniSTS	Rnor5.0
RGSC_v3.4	15	104,418,791 - 104,418,993	UniSTS	RGSC3.4
Celera	15	95,363,626 - 95,363,828	UniSTS
RH 3.4 Map	15	648.0	UniSTS
Cytogenetic Map	15	q24	UniSTS

BE119291

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	97,000,581 - 97,000,734 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	105,254,318 - 105,254,470	NCBI	Rnor6.0
Rnor_5.0	15	108,662,847 - 108,662,999	UniSTS	Rnor5.0
RGSC_v3.4	15	104,914,246 - 104,914,398	UniSTS	RGSC3.4
Celera	15	95,826,526 - 95,826,678	UniSTS
RH 3.4 Map	15	688.4	UniSTS
Cytogenetic Map	15	q24	UniSTS

G45161

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	96,818,519 - 96,818,689 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	104,548,511 - 104,548,678	NCBI	Rnor6.0
Rnor_6.0	15	105,064,210 - 105,064,377	NCBI	Rnor6.0
Rnor_5.0	15	107,960,268 - 107,960,435	UniSTS	Rnor5.0
Rnor_5.0	15	108,472,202 - 108,472,369	UniSTS	Rnor5.0
RGSC_v3.4	15	104,725,362 - 104,725,529	UniSTS	RGSC3.4
Celera	15	95,645,215 - 95,645,392	UniSTS
Cytogenetic Map	15	q24	UniSTS

Hs6st3

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	97,000,254 - 97,000,444 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	105,253,991 - 105,254,180	NCBI	Rnor6.0
Rnor_5.0	15	108,662,520 - 108,662,709	UniSTS	Rnor5.0
Celera	15	95,826,199 - 95,826,388	UniSTS
Cytogenetic Map	15	q24	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
7	5	32	136	54	47	25	21	25	6	179	83	9	113	60	84	22	11	11

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001271404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000057567

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	15	104,448,623 - 104,449,469 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000071685

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	15	105,253,485 - 105,254,198 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093519

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	102,688,365 - 103,408,384 (+)	Ensembl
mRatBN7.2 Ensembl	15	96,281,646 - 97,000,462 (+)	Ensembl
Rnor_6.0 Ensembl	15	104,448,600 - 105,254,214 (+)	Ensembl

RefSeq Acc Id:

NM_001271404 ⟹ NP_001258333

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	102,688,420 - 103,407,725 (+)	NCBI
mRatBN7.2	15	96,281,502 - 97,000,804 (+)	NCBI
Rnor_6.0	15	104,448,479 - 105,254,540 (+)	NCBI
Rnor_5.0	15	108,635,603 - 108,663,069 (+)	NCBI
Rnor_5.0	15	107,871,035 - 107,871,884 (+)	NCBI
Celera	15	95,121,926 - 95,826,748 (+)	NCBI

Sequence:

show sequence

AGACAGTCACGCTCTTTGGCGGTAGGGGCATGGAGGAGCGGCGGGCTCCGAGCCGCGCCCCGGA
GTCCCCGAAACTTCCGAGCAGGCGCTCGATCGCGCCGCTGCCGCCGCAGCTACCTCACCTGCCG
GCCTGAGAGCGGGACCATGGATGAAAGGTTCAACAAGTGGCTGCTGACGCCGGTGCTCACTCTC
CTCTTCGTGGTCATCATGTACCAGTACGTGTCCCCTTCCTGCTCCAGCTCCTGCACCAACTTCG
GGGAGCAGCTCCGCTCCGGGGAGGCTCGCCCGCCCGCTGTCCCGAGTCCTGCCCGACGAGCACA
GGCACCCCCGGATGAGTGGGAGCGGCGGCCCCAGCTGCCACCGCCACCCCGGGGACCGCCCGAG
GGGTCTCGTGGGGTCGCGGCTCCGGAGGATGAGGATGAGGATCCCGGAGACCCGGAGGAGGAGG
AAGAAGAGGAGGAGGAGCCGGACCCCGAGGCGCCCGAAAACGGCTCCCTGCCCCGGTTCGTGCC
GCGCTTCAACTTCACCCTGAAGGACCTGACCCGCTTCGTGGACTTCAACATCAAAGGGCGCGAC
GTGATCGTGTTCCTGCACATCCAGAAGACCGGGGGCACCACGTTCGGCCGGCACCTGGTGAAGA
ACATTCGCCTGGAGCAGCCATGCAGCTGCAAAGCTGGCCAGAAAAAGTGCACCTGCCACCGGCC
GGGCAAGAAGGAGACCTGGCTCTTCTCCCGCTTCTCCACCGGCTGGAGCTGCGGGCTGCATGCT
GACTGGACCGAGCTCACCAACTGCGTGCCGGCCATCATGGAGAAGAAGGATTGTCCCCGCAATC
ACAGCCACACCAGGAATTTCTACTACATCACAATGTTGCGGGACCCGGTGTCACGTTACCTGAG
TGAATGGAAACACGTTCAACGAGGGGCCACATGGAAAACCTCTCTCCATATGTGTGATGGAAGA
AGCCCCACCCCAGATGAGCTGCCTACCTGCTATCCTGGGGATGACTGGTCTGGGGTCAGCTTGC
GGGAGTTCATGGATTGTAGCTACAACCTGGCTAACAACCGCCAAGTCCGCATGCTGGCTGACCT
CAGCCTAGTGGGCTGCTACAACTTGACTTTCATGAATGAGAGTGAGCGCAACACCATCCTACTG
CAGAGTGCTAAGAACAACCTAAAGAACATGGCCTTCTTTGGGCTTACTGAATTCCAGAGGAAGA
CACAGTTTCTCTTTGAGAGGACATTCAACTTGAAGTTCATTTCTCCATTCACACAGTTCAACAT
CACACGGGCTTCCAATGTGGACATCAATGATGGAGCCCGTCAGCACATTGAGGAGTTGAATTTC
CTGGACATGCAGCTTTATGAGTATGCAAAGGATCTCTTTCAGCAACGCTACCACCACACCAAAC
AGCTAGAGCACCAGAGGGACCGACAAAAGAGGCGTGAGGAGCGGAGGCTGCATCGAGAGCACAG
AGCACATCGGTGGCCCAAAGAGGATAGGGCCATAGAGGGGACTGTCACTGAGGACTACAACAGC
CAGGTGGTTAGATGGTGACCCTCTGCCTGCTCCTTTTTATGAAGGGAGATAAGCAGGCACCTCC
TCCTTCTCTTGGATTACTTGGAAAAGGTTGGGCCATGATGAGGACCCCTGGCTTTATGTGACTT
AATTTAGACACCTGCTTCCTCTTTGTCTTCATTTTCAATCCAGCTGGAGATTTCTCCTTCTTTT
CTAGACATTTTCTGATCACTGGTATTAGGTGGGGGTAAATATATCTGACAGACCACTGTAGAGG
GGGTCAGGAAAGAGGCTTCCAGAAGGAGAAAGCTTGTAGTATCTTTGCCACTCCCAGTGGGTCA
ATTTAGGAACCTGGAACCCACAGAAGCACACAGGAAACCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001258333	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000079301
	ENSRNOP00000079301.1

RefSeq Acc Id:	NP_001258333 ⟸ NM_001271404
- Peptide Label:	precursor
- UniProtKB:	A0A8I5ZN51 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDERFNKWLLTPVLTLLFVVIMYQYVSPSCSSSCTNFGEQLRSGEARPPAVPSPARRAQAPPDE WERRPQLPPPPRGPPEGSRGVAAPEDEDEDPGDPEEEEEEEEEPDPEAPENGSLPRFVPRFNFT LKDLTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKET WLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCPRNHSHTRNFYYITMLRDPVSRYLSEWKHV QRGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCSYNLANNRQVRMLADLSLVGC YNLTFMNESERNTILLQSAKNNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASN VDINDGARQHIEELNFLDMQLYEYAKDLFQQRYHHTKQLEHQRDRQKRREERRLHREHRAHRWP KEDRAIEGTVTEDYNSQVVRW hide sequence

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305888	AgrOrtholog
BioCyc Gene	G2FUF-12425	BioCyc
BioCyc Pathway	PWY-6558 [heparan sulfate biosynthesis]	BioCyc
BioCyc Pathway Image	PWY-6558	BioCyc
Ensembl Genes	ENSRNOG00000037886	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000093519	ENTREZGENE
	ENSRNOT00000093519.2	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	Heparan_SO4-6-sulfoTrfase	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	Sulfotransferase	UniProtKB/TrEMBL
KEGG Report	rno:364476	UniProtKB/TrEMBL
NCBI Gene	364476	ENTREZGENE
PANTHER	HEPARAN-SULFATE 6-O-SULFOTRANSFERASE 3	UniProtKB/TrEMBL
	PTHR12812	UniProtKB/TrEMBL
Pfam	Sulfotransfer_2	UniProtKB/TrEMBL
PhenoGen	Hs6st3	PhenoGen
RatGTEx	ENSRNOG00000037886	RatGTEx
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A8I5ZN51	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-05-24	Hs6st3	heparan sulfate 6-O-sulfotransferase 3	RGD1560050	similar to heparan sulfate 6-sulfotransferase 3	Data merged from RGD:1560050	1643240	APPROVED
2008-04-30	Hs6st3	heparan sulfate 6-O-sulfotransferase 3	Hs6st3_predicted	heparan sulfate 6-O-sulfotransferase 3 (predicted)	'predicted' is removed	2292626	APPROVED
2008-04-30	RGD1560050	similar to heparan sulfate 6-sulfotransferase 3	RGD1560050_predicted	similar to heparan sulfate 6-sulfotransferase 3 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1560050_predicted	similar to heparan sulfate 6-sulfotransferase 3 (predicted)	LOC306170	similar to heparan sulfate 6-sulfotransferase 3	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC306170	similar to heparan sulfate 6-sulfotransferase 3			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-01-12	Hs6st3_predicted	heparan sulfate 6-O-sulfotransferase 3 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

BioCyc Pathways

Send us a Message

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

BioCyc Pathways