Tectb (tectorin beta) - Rat Genome Database

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Gene: Tectb (tectorin beta) Rattus norvegicus
Analyze
Symbol: Tectb
Name: tectorin beta
RGD ID: 1305835
Description: Predicted to be an extracellular matrix structural constituent. Predicted to be located in extracellular matrix. Predicted to be active in cell surface and extracellular space. Orthologous to human TECTB (tectorin beta); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: beta-tectorin; LOC292124
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81264,226,963 - 264,242,010 (+)NCBIGRCr8
mRatBN7.21254,221,621 - 254,236,669 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1254,221,621 - 254,236,669 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1262,426,711 - 262,441,717 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01269,132,790 - 269,147,794 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01261,780,477 - 261,795,483 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01275,957,698 - 275,976,572 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1275,957,698 - 275,976,572 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01283,358,674 - 283,377,599 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41261,482,994 - 261,498,415 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11261,694,167 - 261,707,830 (+)NCBI
Celera1249,928,360 - 249,943,433 (+)NCBICelera
Cytogenetic Map1q55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9079715  


Genomics

Comparative Map Data
Tectb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81264,226,963 - 264,242,010 (+)NCBIGRCr8
mRatBN7.21254,221,621 - 254,236,669 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1254,221,621 - 254,236,669 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1262,426,711 - 262,441,717 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01269,132,790 - 269,147,794 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01261,780,477 - 261,795,483 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01275,957,698 - 275,976,572 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1275,957,698 - 275,976,572 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01283,358,674 - 283,377,599 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41261,482,994 - 261,498,415 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11261,694,167 - 261,707,830 (+)NCBI
Celera1249,928,360 - 249,943,433 (+)NCBICelera
Cytogenetic Map1q55NCBI
TECTB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810112,283,400 - 112,305,038 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10112,283,400 - 112,305,038 (+)EnsemblGRCh38hg38GRCh38
GRCh3710114,043,158 - 114,064,796 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610114,033,483 - 114,053,060 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410114,033,482 - 114,053,060NCBI
Celera10107,771,025 - 107,790,599 (+)NCBICelera
Cytogenetic Map10q25.2NCBI
HuRef10107,671,685 - 107,693,068 (+)NCBIHuRef
CHM1_110114,325,466 - 114,346,829 (+)NCBICHM1_1
T2T-CHM13v2.010113,174,401 - 113,196,039 (+)NCBIT2T-CHM13v2.0
Tectb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391955,169,158 - 55,184,745 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1955,169,165 - 55,184,745 (+)EnsemblGRCm39 Ensembl
GRCm381955,180,726 - 55,196,313 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1955,180,733 - 55,196,313 (+)EnsemblGRCm38mm10GRCm38
MGSCv371955,255,375 - 55,270,803 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361955,234,135 - 55,249,563 (+)NCBIMGSCv36mm8
Celera1957,371,980 - 57,387,427 (+)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1951.13NCBI
Tectb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543117,413,841 - 17,425,192 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543117,413,841 - 17,425,192 (+)NCBIChiLan1.0ChiLan1.0
TECTB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28124,159,821 - 124,181,870 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110124,165,157 - 124,187,206 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010108,875,621 - 108,897,402 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110112,315,820 - 112,336,808 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10112,315,820 - 112,336,800 (+)Ensemblpanpan1.1panPan2
TECTB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12823,359,019 - 23,378,150 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2823,359,162 - 23,376,760 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2823,510,832 - 23,529,940 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02823,891,255 - 23,910,380 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2823,891,371 - 23,908,987 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12823,448,582 - 23,467,680 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02823,459,707 - 23,478,835 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02823,655,112 - 23,674,215 (+)NCBIUU_Cfam_GSD_1.0
Tectb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721322,678,008 - 22,709,315 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364862,852,016 - 2,883,265 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364862,852,015 - 2,883,265 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TECTB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14122,691,421 - 122,710,351 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114122,690,796 - 122,711,124 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214133,604,709 - 133,624,167 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TECTB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19105,152,311 - 105,196,040 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9105,175,643 - 105,195,420 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604866,378,589 - 66,399,862 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tectb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473734,146,587 - 34,157,957 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473734,144,175 - 34,158,417 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tectb
59 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:443
Count of miRNA genes:257
Interacting mature miRNAs:298
Transcripts:ENSRNOT00000021041
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
1549910Bw54Body weight QTL 540.05body mass (VT:0001259)body weight (CMO:0000012)1214647894259647894Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1214647894259647894Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1222363780260522016Rat
631690Scl5Serum cholesterol level QTL 52.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1236125214260522016Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
10053715Scort24Serum corticosterone level QTL 242.130.0088blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1221414816260522016Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1223201027260522016Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
631837Niddm35Non-insulin dependent diabetes mellitus QTL 350.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1238699859259647894Rat
631836Stl31Serum triglyceride level QTL 314.645e-06blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1237147813260522016Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1300108Rf8Renal function QTL 83.75renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1228581588259647894Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1224054293260122809Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1225126575260522016Rat
7387289Uae45Urinary albumin excretion QTL 452.860.0021urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1223262787260522016Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1224054293260122809Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1221264111259647894Rat
1598839Rf56Renal function QTL 56renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1245907761257976495Rat
1581544Rf52Renal function QTL 520.05urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)1232156370259647894Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
631536Lnnr2Liver neoplastic nodule remodeling QTL 22.90.0005liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)1233948574260522016Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1224569538260122809Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
734768Niddm59Non-insulin dependent diabetes mellitus QTL 59body mass (VT:0001259)body weight (CMO:0000012)1213843987258843987Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1216255568260522016Rat
631669Iddm9Insulin dependent diabetes mellitus QTL 92.80.039blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1233190394258625266Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1218748008257976495Rat
1358890Bp259Blood pressure QTL 2593.06arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1210702053260522016Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1218753816256448513Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
8 11 40 94 62 61 30 24 30 6 144 85 74 13 42 31

Sequence


Ensembl Acc Id: ENSRNOT00000021041   ⟹   ENSRNOP00000021041
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1254,221,621 - 254,236,669 (+)Ensembl
Rnor_6.0 Ensembl1275,957,698 - 275,976,572 (+)Ensembl
RefSeq Acc Id: NM_001106200   ⟹   NP_001099670
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81264,226,963 - 264,242,010 (+)NCBI
mRatBN7.21254,221,621 - 254,236,669 (+)NCBI
Rnor_6.01275,957,698 - 275,976,572 (+)NCBI
Rnor_5.01283,358,674 - 283,377,599 (+)NCBI
RGSC_v3.41261,482,994 - 261,498,415 (+)RGD
Celera1249,928,360 - 249,943,433 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001099670 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL94457 (Get FASTA)   NCBI Sequence Viewer  
  EDL94458 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021041.3
RefSeq Acc Id: NP_001099670   ⟸   NM_001106200
- Peptide Label: precursor
- UniProtKB: D4AC15 (UniProtKB/TrEMBL),   A6JHY3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021041   ⟸   ENSRNOT00000021041
Protein Domains
ZP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AC15-F1-model_v2 AlphaFold D4AC15 1-329 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305835 AgrOrtholog
BioCyc Gene G2FUF-55348 BioCyc
Ensembl Genes ENSRNOG00000015671 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021041.4 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.4100 UniProtKB/TrEMBL
InterPro Endoglin/CD105 UniProtKB/TrEMBL
  Endoglin/CD105_CS UniProtKB/TrEMBL
  ZP-C UniProtKB/TrEMBL
KEGG Report rno:292124 UniProtKB/TrEMBL
NCBI Gene 292124 ENTREZGENE
PANTHER BETA-TECTORIN UniProtKB/TrEMBL
  ENDOGLIN/TGF-BETA RECEPTOR TYPE III UniProtKB/TrEMBL
Pfam Zona_pellucida UniProtKB/TrEMBL
PhenoGen Tectb PhenoGen
PROSITE ZP_1 UniProtKB/TrEMBL
  ZP_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015671 RatGTEx
SMART SM00241 UniProtKB/TrEMBL
UniProt A6JHY3 ENTREZGENE, UniProtKB/TrEMBL
  D4AC15 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Tectb  tectorin beta   Tectb_predicted  tectorin beta (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Tectb_predicted  tectorin beta (predicted)      Symbol and Name status set to approved 70820 APPROVED