Tspan14 (tetraspanin 14) - Rat Genome Database

Name: Tspan14
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Tspan14 (tetraspanin 14) Rattus norvegicus

Analyze

Symbol:

Tspan14

Name:

tetraspanin 14

RGD ID:

1305714

Description:

Predicted to enable enzyme binding activity. Predicted to be involved in positive regulation of Notch signaling pathway; protein localization to plasma membrane; and protein maturation. Predicted to be located in cell surface and tetraspanin-enriched microdomain. Predicted to be active in plasma membrane. Orthologous to human TSPAN14 (tetraspanin 14); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; DDT.

Type:

protein-coding

RefSeq Status:

INFERRED

Previously known as:

LOC306324; RGD1305714; similar to tetraspanin similar to TM4SF9; tetraspanin-14

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TSPAN14 (tetraspanin 14)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Tspan14 (tetraspanin 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tspan14 (tetraspanin 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TSPAN14 (tetraspanin 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TSPAN14 (tetraspanin 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tspan14 (tetraspanin 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TSPAN14 (tetraspanin 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TSPAN14 (tetraspanin 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tspan14 (tetraspanin 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TSPAN14 (tetraspanin 14)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tspan14 (tetraspanin 14)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tspan14 (tetraspanin 14)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Tsp26A	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	tsp-12	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	16	16,784,242 - 16,841,368 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	16,783,234 - 16,841,400 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	16,852,777 - 16,880,132 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	16	17,979,528 - 18,006,887 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	16	16,905,672 - 16,933,029 (-)	NCBI	Rnor_WKY
Rnor_6.0	16	17,538,855 - 17,595,960 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	17,538,855 - 17,595,960 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	17,421,546 - 17,478,815 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	17,340,946 - 17,397,964 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	17,339,921 - 17,398,046 (-)	NCBI
Celera	16	17,010,568 - 17,067,598 (-)	NCBI		Celera
Cytogenetic Map	16	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

caffeine (ISO)

CGP 52608 (ISO)

choline (ISO)

cyclosporin A (ISO)

DDT (EXP)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dicrotophos (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

gentamycin (EXP)

glafenine (EXP)

ivermectin (ISO)

ketamine (EXP)

L-methionine (ISO)

lipopolysaccharide (ISO)

pirinixic acid (ISO)

propanal (ISO)

quercitrin (ISO)

rotenone (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

selenium atom (ISO)

succimer (ISO)

sulforaphane (ISO)

tert-butyl hydroperoxide (ISO)

thioacetamide (EXP)

valproic acid (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of Notch signaling pathway (ISO)

protein localization to plasma membrane (ISO)

protein maturation (ISO)

Cellular Component

cell surface (ISO)

plasma membrane (IBA,ISO)

tetraspanin-enriched microdomain (ISO)

Molecular Function

enzyme binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:23035126	PMID:23091066

Genomics

Comparative Map Data

Tspan14
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	16	16,784,242 - 16,841,368 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	16,783,234 - 16,841,400 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	16,852,777 - 16,880,132 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	16	17,979,528 - 18,006,887 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	16	16,905,672 - 16,933,029 (-)	NCBI	Rnor_WKY
Rnor_6.0	16	17,538,855 - 17,595,960 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	17,538,855 - 17,595,960 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	17,421,546 - 17,478,815 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	17,340,946 - 17,397,964 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	17,339,921 - 17,398,046 (-)	NCBI
Celera	16	17,010,568 - 17,067,598 (-)	NCBI		Celera
Cytogenetic Map	16	p14	NCBI

TSPAN14
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	80,454,310 - 80,522,631 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	10	80,454,265 - 80,533,124 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	82,214,066 - 82,282,387 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	82,204,047 - 82,269,366 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	82,204,046 - 82,269,364	NCBI
Celera	10	76,204,371 - 76,272,722 (+)	NCBI		Celera
Cytogenetic Map	10	q23.1	NCBI
HuRef	10	76,057,216 - 76,125,170 (+)	NCBI		HuRef
CHM1_1	10	82,497,044 - 82,565,383 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	81,323,409 - 81,391,729 (+)	NCBI		T2T-CHM13v2.0

Tspan14
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	40,628,384 - 40,689,030 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	40,628,402 - 40,688,764 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	40,906,427 - 40,967,073 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	40,906,445 - 40,966,807 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	41,719,733 - 41,780,096 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	39,815,157 - 39,875,520 (-)	NCBI		MGSCv36	mm8
Celera	14	37,065,722 - 37,125,273 (-)	NCBI		Celera
Cytogenetic Map	14	B	NCBI
cM Map	14	22.36	NCBI

Tspan14
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955510	448,668 - 490,635 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955510	463,548 - 490,635 (+)	NCBI	ChiLan1.0	ChiLan1.0

TSPAN14
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	10	80,462,234 - 80,521,771 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	80,464,131 - 80,521,771 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	10	76,854,589 - 76,922,144 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

TSPAN14
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	29,589,840 - 29,635,448 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	29,586,264 - 29,634,694 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	29,705,463 - 29,760,708 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	29,883,249 - 29,938,436 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	29,883,065 - 29,938,439 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	29,752,837 - 29,807,967 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	29,955,243 - 30,010,372 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	30,309,656 - 30,364,838 (+)	NCBI		UU_Cfam_GSD_1.0

Tspan14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	51,064,861 - 51,125,154 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936716	285,389 - 342,947 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936716	285,395 - 342,953 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TSPAN14
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	82,305,714 - 82,364,659 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	82,305,594 - 82,364,675 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	88,914,194 - 88,972,588 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TSPAN14
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	51,317,651 - 51,381,388 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	51,319,166 - 51,347,968 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	11,639,848 - 11,706,005 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tspan14
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624841	6,603,374 - 6,633,579 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624841	6,603,373 - 6,655,475 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tspan14
387 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	156
Count of miRNA genes:	104
Interacting mature miRNAs:	120
Transcripts:	ENSRNOT00000014772
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1600369	Hcas8	Hepatocarcinoma susceptibility QTL 8			liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	16	1	22477621	Rat
631830	Alc7	Alcohol consumption QTL 7	2.9		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	1	26727669	Rat
634355	Rends4	Renal damage susceptibility QTL 4		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	16	1	26727669	Rat
1582235	Insul8	Insulin level QTL 8	3.3	0.0063	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	16	1	26727669	Rat
9590151	Scort8	Serum corticosterone level QTL 8	8.45	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	16	1	30836262	Rat
2302380	Slep6	Serum leptin concentration QTL 6	3.36		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	1	32139025	Rat
2307172	Activ4	Activity QTL 4	3.71	0.00023	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	1	33418960	Rat
1354584	Despr6	Despair related QTL 6	3.1	0.0067	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	16	1	39533930	Rat
2303566	Bw90	Body weight QTL 90	2		body mass (VT:0001259)	body weight (CMO:0000012)	16	1	39533930	Rat
631561	Hcuc2	Hepatic copper content QTL 2	2.8		liver copper amount (VT:0003065)	liver total copper weight (CMO:0001507)	16	1	39533949	Rat
6903319	Bw114	Body weight QTL 114	2.7	0.0037	body mass (VT:0001259)	body weight (CMO:0000012)	16	1	43534949	Rat
7411664	Foco30	Food consumption QTL 30	11	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	1	44588133	Rat
1354625	Despr7	Despair related QTL 7	3.16	0.016	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	16	1	44977551	Rat
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	380245	80345693	Rat
2293343	Glom16	Glomerulus QTL 16	7.4		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	16	832236	46053497	Rat
2312660	Bw95	Body weight QTL 95		0.05	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	16	832236	59492508	Rat
2312663	Slep9	Serum leptin concentration QTL 9		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	832236	59492508	Rat
2312666	Insul16	Insulin level QTL 16		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	16	832236	59492508	Rat
2312669	Stl23	Serum triglyceride level QTL 23		0.01	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	16	832236	59492508	Rat
1300133	Rf24	Renal function QTL 24	3.64		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	16	3380150	21361552	Rat
2306902	Bp339	Blood pressure QTL 339		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	3380150	43025077	Rat
70183	BpQTLcluster13	Blood pressure QTL cluster 13	3.654		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	16	4227609	43025077	Rat
70183	BpQTLcluster13	Blood pressure QTL cluster 13	3.654		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	4227609	43025077	Rat
70183	BpQTLcluster13	Blood pressure QTL cluster 13	3.654		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	16	4227609	43025077	Rat
737819	Hcas4	Hepatocarcinoma susceptibility QTL 4	4.43		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	16	4227609	46975965	Rat
61405	Niddm6	Non-insulin dependent diabetes mellitus QTL 6	3.66	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	16	4227609	48972724	Rat
61338	Bp23	Blood pressure QTL 23	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	4227609	49227609	Rat
737826	Alc11	Alcohol consumption QTL 11	3.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4227609	60252231	Rat
61372	Bp40	Blood pressure QTL 40	2.2		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	16	4227730	17696785	Rat
631517	Scl9	Serum cholesterol level QTL 9	3.3		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	16	15726433	21034895	Rat

Markers in Region

AW521715

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	16,842,238 - 16,842,401 (-)	MAPPER	mRatBN7.2
Rnor_6.0	16	17,537,812 - 17,537,974	NCBI	Rnor6.0
Rnor_5.0	16	17,420,273 - 17,420,435	UniSTS	Rnor5.0
RGSC_v3.4	16	17,399,223 - 17,399,385	UniSTS	RGSC3.4
Celera	16	17,068,465 - 17,068,627	UniSTS
RH 3.4 Map	16	164.11	UniSTS
Cytogenetic Map	16	p14	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	36	57	41	19	41	2	3	74	35	34	11	2
Low		7					6	8			7		6
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001169127	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474031	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000014772 ⟹ ENSRNOP00000014772

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	16,783,234 - 16,841,400 (-)	Ensembl
Rnor_6.0 Ensembl	16	17,538,855 - 17,595,960 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000095616 ⟹ ENSRNOP00000097225

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	16,783,234 - 16,841,400 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000113745 ⟹ ENSRNOP00000087472

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	16,783,308 - 16,796,270 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000117906 ⟹ ENSRNOP00000078197

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	16,783,308 - 16,796,950 (-)	Ensembl

RefSeq Acc Id:

NM_001169127 ⟹ NP_001162598

RefSeq Status:

INFERRED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	16	16,784,242 - 16,841,368 (-)	NCBI
Rnor_6.0	16	17,538,855 - 17,595,960 (+)	NCBI
Rnor_5.0	16	17,421,546 - 17,478,815 (+)	NCBI
RGSC_v3.4	16	17,340,946 - 17,397,964 (-)	RGD
Celera	16	17,010,568 - 17,067,598 (-)	RGD

Sequence:

show sequence

CGTGCTGCCGCCGCTGCTGCCGCGCCCGGGTCCTGCTTCTCGGAAGATGCACTATTACAGATAC
TCGAACGCCGAGGTCAGCTGCTGGTACAAGTACCTGCTCTTCAGCTACAATATCGTCTTTTGGT
TGGCTGGAGTTGTTTTCCTTGGAGTCGGGCTGTGGGCATGGAGCGAAAAGGGCGTGCTGTCCGA
CCTCACGAAGGTGACCCGGTTGCATGGAATCGACCCTGTCGTGCTGGTCTTGATGGTGGGCGTG
GTGATGTTCACACTGGGATTCGCGGGCTGTGTCGGGGCCCTGCGGGAGAACATCTGCCTGCTCA
AGTTTTTCTGTGGGGCCATTGTGCTCATCTTCTTCCTGGAACTGGCTGTGGCTGTGTTGGCCTT
TTTATTCCAAGACTGGGTGAGGGATCGTTTCCGGGAATTCTTCGAGAGCAACATCAGGTCCTAT
CGGGATGACATTGACCTGCAGAACCTCATTGACTCTCTTCAGAAAGCCAATCAGTGCTGTGGGG
CTTACGGCCCTGAAGACTGGGACCTCAATGTCTACTTCAACTGCAGTGGTGCCAGCTACAGCCG
AGAGAAATGTGGGGTGCCCTTCTCCTGCTGTGTGCCGGACCCTGCACAAAAAGTCGTGAACACA
CAGTGTGGCTATGATGTCAGGATTCAGCTGAAGAGCAAGTGGGATGAGTTCATCTTCACGAAGG
GGTGCATCCAGGCTCTGGAGGGCTGGCTTCCCAGGAACATCTACATTGTGGCTGGTGTCTTCAT
TGCCATCTCCCTGCTGCAGATCTTCGGCATCTTCCTGGCAAGGACCCTGATCTCAGACATTGAG
GCAGTGAAGGCAGGCCATCACTTCTGAGGCGCAGGTGCAGCAGATGGAGCTGAGCCACATGGAG
AGGTCAAGCCTTTCACTGTCCAGCAGCGGCAGAAGTCGACATTAGCCACCTACAACCAGACCCC
AGTCTTCCGCATCAGCACGATATGGCCTCTCTGTTTCTTCTTGCTGGTGCTGAAGGCCAAGGCC
CCTTCTCATCTGCTCACACTTGACATGGCACCTCTGAAGGCCCAGAGACAGAGAATGTGTTTTT
ATGTGGAGTAGTAACTCTGAGGACAGATGGGCTCCCATGGCCGCAGGAAAGGCTTAATGGCCCT
TACAGAGCCCAAGAGCATCTGCAGGTCCCCACCTACTCAGTAAGGCTTAGGTACATGCTCAGCT
ATTCTCTTCTGTGGGCAGAGCATCAGTATGGGACCAGCATTGAGGACAAGGCTTCTGCCTCCCT
TGGATCAAGATGGATGGAGAGGGATAAGTGGTCCAGTGGTTCCCCTCCTGTCAACAAGGCTCAT
GGTGGTGCAAACGTGCCAGGGGTTTGCAGAATCCTCAGCCATGTCCAAGTGAAGTATGCCTGAG
CCAGCTATAACCGGTCTTGGGAAGCACATCATCACTGCCTTCCAAGTCTACACTGCTCTCCCAG
G

hide sequence

Protein Sequences


Protein RefSeqs	NP_001162598	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL90878	(Get FASTA)	NCBI Sequence Viewer
	EDL90879	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001162598 ⟸ NM_001169127

- UniProtKB:

D4A0Z1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MHYYRYSNAEVSCWYKYLLFSYNIVFWLAGVVFLGVGLWAWSEKGVLSDLTKVTRLHGIDPVVL
VLMVGVVMFTLGFAGCVGALRENICLLKFFCGAIVLIFFLELAVAVLAFLFQDWVRDRFREFFE
SNIRSYRDDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPA
QKVVNTQCGYDVRIQLKSKWDEFIFTKGCIQALEGWLPRNIYIVAGVFIAISLLQIFGIFLART
LISDIEAVKAGHHF

hide sequence

RefSeq Acc Id:

ENSRNOP00000014772 ⟸ ENSRNOT00000014772

RefSeq Acc Id:

ENSRNOP00000087472 ⟸ ENSRNOT00000113745

RefSeq Acc Id:

ENSRNOP00000078197 ⟸ ENSRNOT00000117906

RefSeq Acc Id:

ENSRNOP00000097225 ⟸ ENSRNOT00000095616

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A0Z1-F1-model_v2	AlphaFold	D4A0Z1	1-270	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699970

Promoter ID:

EPDNEW_R10492

Type:

initiation region

Name:

Tspan14_1

Description:

tetraspanin 14

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	17,538,835 - 17,538,895	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305714	AgrOrtholog
BioCyc Gene	G2FUF-11914	BioCyc
Ensembl Genes	ENSRNOG00000010813	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000014772	ENTREZGENE
	ENSRNOP00000014772.4	UniProtKB/TrEMBL
	ENSRNOP00000078197.1	UniProtKB/TrEMBL
	ENSRNOP00000087472.1	UniProtKB/TrEMBL
	ENSRNOP00000097225.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000014772	ENTREZGENE
	ENSRNOT00000014772.7	UniProtKB/TrEMBL
	ENSRNOT00000095616.1	UniProtKB/TrEMBL
	ENSRNOT00000113745.1	UniProtKB/TrEMBL
	ENSRNOT00000117906.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.1450.10	UniProtKB/TrEMBL
InterPro	Tetraspanin	UniProtKB/TrEMBL
	Tetraspanin_CS	UniProtKB/TrEMBL
	Tetraspanin_EC2	UniProtKB/TrEMBL
	Tetraspanin_sub	UniProtKB/TrEMBL
KEGG Report	rno:306324	UniProtKB/TrEMBL
NCBI Gene	306324	ENTREZGENE
PANTHER	PTHR19282	UniProtKB/TrEMBL
Pfam	Tetraspannin	UniProtKB/TrEMBL
PhenoGen	Tspan14	PhenoGen
PIRSF	Tetraspanin	UniProtKB/TrEMBL
PROSITE	TM4_1	UniProtKB/TrEMBL
Superfamily-SCOP	Tetraspanin	UniProtKB/TrEMBL
UniProt	A0A8I5Y772_RAT	UniProtKB/TrEMBL
	A0A8I6ARC5_RAT	UniProtKB/TrEMBL
	A0A8I6GG14_RAT	UniProtKB/TrEMBL
	D4A0Z1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Tspan14	tetraspanin 14	Tspan14_predicted	tetraspanin 14 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Tspan14_predicted	tetraspanin 14 (predicted)	RGD1305714_predicted	similar to tetraspanin similar to TM4SF9 (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1305714_predicted	similar to tetraspanin similar to TM4SF9 (predicted)	LOC306324_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC306324_predicted	similar to tetraspanin similar to TM4SF9 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD