![]()
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tspan14 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Tspan14 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TSPAN14 mRNA | CTD | PMID:22206623 | Tspan14 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Tspan14 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of TSPAN14 mRNA | CTD | PMID:17942748 | Tspan14 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Tspan14 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TSPAN14 mRNA | CTD | PMID:17942748 | Tspan14 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Tspan14 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TSPAN14 mRNA | CTD | PMID:17942748 | Tspan14 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TSPAN14 mRNA | CTD | PMID:33387578 | Tspan14 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tspan14 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TSPAN14 mRNA | CTD | PMID:21570461 | Tspan14 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Tspan14 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of TSPAN14 mRNA | CTD | PMID:39298647 | Tspan14 | Rat | 4,4'-sulfonyldiphenol | increases methylation | ISO | Tspan14 (Mus musculus) | 6480464 | bisphenol S results in increased methylation of TSPAN14 exon | CTD | PMID:33297965 | Tspan14 | Rat | aflatoxin B1 | decreases methylation | ISO | TSPAN14 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TSPAN14 polyA tail | CTD | PMID:30157460 | Tspan14 | Rat | Aflatoxin B2 alpha | decreases methylation | ISO | TSPAN14 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of TSPAN14 intron; aflatoxin B2 results in decreased methylation more ... | CTD | PMID:30157460 | Tspan14 | Rat | all-trans-retinoic acid | increases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of TSPAN14 mRNA | CTD | PMID:23830798|PMID:33167477 | Tspan14 | Rat | arsane | affects methylation | ISO | TSPAN14 (Homo sapiens) | 6480464 | Arsenic affects the methylation of TSPAN14 gene | CTD | PMID:25304211 | Tspan14 | Rat | arsenic atom | affects methylation | ISO | TSPAN14 (Homo sapiens) | 6480464 | Arsenic affects the methylation of TSPAN14 gene | CTD | PMID:25304211 | Tspan14 | Rat | arsenous acid | decreases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of TSPAN14 mRNA | CTD | PMID:29633893 | Tspan14 | Rat | benzo[a]pyrene | decreases expression | ISO | Tspan14 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of TSPAN14 mRNA | CTD | PMID:19770486|PMID:21569818 | Tspan14 | Rat | benzo[a]pyrene | decreases methylation | ISO | TSPAN14 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of TSPAN14 promoter | CTD | PMID:27901495 | Tspan14 | Rat | benzo[a]pyrene | affects methylation | ISO | TSPAN14 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TSPAN14 5' UTR | CTD | PMID:27901495 | Tspan14 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Tspan14 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of TSPAN14 mRNA | CTD | PMID:34319233 | Tspan14 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of TSPAN14 gene | CTD | PMID:28505145 | Tspan14 | Rat | bisphenol A | affects expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | bisphenol A affects the expression of TSPAN14 mRNA | CTD | PMID:30903817 | Tspan14 | Rat | cadmium dichloride | increases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of TSPAN14 mRNA | CTD | PMID:38382870 | Tspan14 | Rat | caffeine | decreases phosphorylation | ISO | TSPAN14 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of TSPAN14 protein | CTD | PMID:35688186 | Tspan14 | Rat | CGP 52608 | multiple interactions | ISO | TSPAN14 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TSPAN14 gene] | CTD | PMID:28238834 | Tspan14 | Rat | choline | multiple interactions | ISO | Tspan14 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Tspan14 | Rat | cyclosporin A | decreases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TSPAN14 mRNA | CTD | PMID:25562108|PMID:27989131 | Tspan14 | Rat | DDT | increases methylation | EXP | | 6480464 | DDT results in increased methylation of TSPAN14 gene | CTD | PMID:30207508 | Tspan14 | Rat | dexamethasone | increases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Dexamethasone results in increased expression of TSPAN14 mRNA | CTD | PMID:25047013 | Tspan14 | Rat | diarsenic trioxide | decreases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of TSPAN14 mRNA | CTD | PMID:29633893 | Tspan14 | Rat | Dibutyl phosphate | affects expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of TSPAN14 mRNA | CTD | PMID:37042841 | Tspan14 | Rat | dicrotophos | increases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of TSPAN14 mRNA | CTD | PMID:28302478 | Tspan14 | Rat | doxorubicin | decreases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TSPAN14 mRNA | CTD | PMID:29803840 | Tspan14 | Rat | elemental selenium | multiple interactions | ISO | TSPAN14 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of TSPAN14 mRNA | CTD | PMID:19244175 | Tspan14 | Rat | elemental selenium | increases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Selenium results in increased expression of TSPAN14 mRNA | CTD | PMID:19244175 | Tspan14 | Rat | enzyme inhibitor | multiple interactions | ISO | TSPAN14 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Tspan14 | Rat | epoxiconazole | decreases expression | ISO | Tspan14 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of TSPAN14 mRNA | CTD | PMID:35436446 | Tspan14 | Rat | ethyl methanesulfonate | increases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of TSPAN14 mRNA | CTD | PMID:23649840 | Tspan14 | Rat | folic acid | multiple interactions | ISO | Tspan14 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TSPAN14 mRNA; [Methionine deficiency co-treated more ... | CTD | PMID:20938992|PMID:22206623 | Tspan14 | Rat | folic acid | decreases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of TSPAN14 mRNA | CTD | PMID:21867686 | Tspan14 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of TSPAN14 mRNA | CTD | PMID:33387578 | Tspan14 | Rat | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of TSPAN14 mRNA | CTD | PMID:24136188 | Tspan14 | Rat | glyphosate | affects methylation | EXP | | 6480464 | Glyphosate affects the methylation of TSPAN14 gene | CTD | PMID:35440735 | Tspan14 | Rat | ivermectin | decreases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of TSPAN14 protein | CTD | PMID:32959892 | Tspan14 | Rat | ketamine | decreases expression | EXP | | 6480464 | Ketamine results in decreased expression of TSPAN14 mRNA | CTD | PMID:20080153 | Tspan14 | Rat | L-methionine | multiple interactions | ISO | Tspan14 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Tspan14 | Rat | lipopolysaccharide | decreases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Lipopolysaccharides results in decreased expression of TSPAN14 mRNA | CTD | PMID:35811015 | Tspan14 | Rat | lipopolysaccharide | multiple interactions | ISO | TSPAN14 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of TSPAN14 mRNA; [S-(1,2-dichlorovinyl)cysteine more ... | CTD | PMID:35811015 | Tspan14 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of TSPAN14 gene | CTD | PMID:35440735 | Tspan14 | Rat | nitrates | multiple interactions | ISO | Tspan14 (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of TSPAN14 more ... | CTD | PMID:35964746 | Tspan14 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tspan14 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of TSPAN14 mRNA | CTD | PMID:36331819 | Tspan14 | Rat | pirinixic acid | decreases expression | ISO | Tspan14 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of TSPAN14 mRNA | CTD | PMID:17426115 | Tspan14 | Rat | propanal | increases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of TSPAN14 mRNA | CTD | PMID:26079696 | Tspan14 | Rat | quercitrin | decreases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | quercitrin results in decreased expression of TSPAN14 mRNA | CTD | PMID:25193878 | Tspan14 | Rat | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of TSPAN14 mRNA | CTD | PMID:28374803 | Tspan14 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | TSPAN14 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of TSPAN14 mRNA; [S-(1,2-dichlorovinyl)cysteine more ... | CTD | PMID:35811015 | Tspan14 | Rat | selenium atom | multiple interactions | ISO | TSPAN14 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of TSPAN14 mRNA | CTD | PMID:19244175 | Tspan14 | Rat | selenium atom | increases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Selenium results in increased expression of TSPAN14 mRNA | CTD | PMID:19244175 | Tspan14 | Rat | sodium arsenite | decreases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of TSPAN14 mRNA | CTD | PMID:38568856 | Tspan14 | Rat | succimer | multiple interactions | ISO | Tspan14 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of TSPAN14 mRNA | CTD | PMID:21641980 | Tspan14 | Rat | sulforaphane | increases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | sulforaphane results in increased expression of TSPAN14 mRNA | CTD | PMID:26833863 | Tspan14 | Rat | tert-butyl hydroperoxide | increases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in increased expression of TSPAN14 mRNA | CTD | PMID:15336504 | Tspan14 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of TSPAN14 mRNA | CTD | PMID:34492290 | Tspan14 | Rat | thiram | decreases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Thiram results in decreased expression of TSPAN14 mRNA | CTD | PMID:38568856 | Tspan14 | Rat | titanium dioxide | decreases methylation | ISO | Tspan14 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of TSPAN14 gene | CTD | PMID:35295148 | Tspan14 | Rat | titanium dioxide | affects methylation | ISO | Tspan14 (Mus musculus) | 6480464 | titanium dioxide affects the methylation of TSPAN14 promoter | CTD | PMID:35295148 | Tspan14 | Rat | valproic acid | decreases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of TSPAN14 mRNA | CTD | PMID:29154799 | Tspan14 | Rat | valproic acid | affects expression | ISO | Tspan14 (Mus musculus) | 6480464 | Valproic Acid affects the expression of TSPAN14 mRNA | CTD | PMID:17292431 | Tspan14 | Rat | valproic acid | increases methylation | ISO | TSPAN14 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of TSPAN14 gene | CTD | PMID:29154799 | Tspan14 | Rat | valproic acid | affects expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TSPAN14 mRNA | CTD | PMID:25979313 | Tspan14 | Rat | vitamin E | multiple interactions | ISO | TSPAN14 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of TSPAN14 mRNA | CTD | PMID:19244175 | Tspan14 | Rat | vitamin E | increases expression | ISO | TSPAN14 (Homo sapiens) | 6480464 | Vitamin E results in increased expression of TSPAN14 mRNA | CTD | PMID:19244175 | |