Fam204a (family with sequence similarity 204, member A) - Rat Genome Database

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Gene: Fam204a (family with sequence similarity 204, member A) Rattus norvegicus
Analyze
Symbol: Fam204a
Name: family with sequence similarity 204, member A
RGD ID: 1305500
Description: Orthologous to human FAM204A (family with sequence similarity 204 member A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; azoxystrobin.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC308004; LOC308004; RGD1305500; similar to hypothetical protein FLJ13188; uncharacterized protein LOC308004
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81269,323,473 - 269,352,772 (-)NCBIGRCr8
mRatBN7.21259,328,551 - 259,366,726 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1259,337,709 - 259,367,077 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1267,543,514 - 267,572,764 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01274,249,546 - 274,278,796 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01266,895,823 - 266,925,136 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01281,343,692 - 281,403,699 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1281,347,536 - 281,376,834 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01288,697,398 - 288,730,537 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41266,749,513 - 266,779,356 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11266,967,048 - 266,990,027 (-)NCBI
Celera1254,985,319 - 255,014,612 (-)NCBICelera
Cytogenetic Map1q55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Fam204a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81269,323,473 - 269,352,772 (-)NCBIGRCr8
mRatBN7.21259,328,551 - 259,366,726 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1259,337,709 - 259,367,077 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1267,543,514 - 267,572,764 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01274,249,546 - 274,278,796 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01266,895,823 - 266,925,136 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01281,343,692 - 281,403,699 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1281,347,536 - 281,376,834 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01288,697,398 - 288,730,537 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41266,749,513 - 266,779,356 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11266,967,048 - 266,990,027 (-)NCBI
Celera1254,985,319 - 255,014,612 (-)NCBICelera
Cytogenetic Map1q55NCBI
FAM204A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810118,297,925 - 118,342,324 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10118,297,925 - 118,342,328 (-)EnsemblGRCh38hg38GRCh38
GRCh3710120,057,437 - 120,101,836 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610120,058,562 - 120,091,808 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410120,058,561 - 120,091,808NCBI
Celera10113,799,164 - 113,832,438 (-)NCBICelera
Cytogenetic Map10q26.11NCBI
HuRef10113,697,636 - 113,730,878 (-)NCBIHuRef
CHM1_110120,352,610 - 120,385,891 (-)NCBICHM1_1
T2T-CHM13v2.010119,192,932 - 119,237,311 (-)NCBIT2T-CHM13v2.0
Fam204a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391960,187,018 - 60,215,137 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1960,187,018 - 60,215,133 (-)EnsemblGRCm39 Ensembl
GRCm381960,197,148 - 60,226,705 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1960,198,586 - 60,226,701 (-)EnsemblGRCm38mm10GRCm38
MGSCv371960,274,489 - 60,302,600 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361960,253,249 - 60,281,360 (-)NCBIMGSCv36mm8
Celera1962,387,664 - 62,415,670 (-)NCBICelera
Cytogenetic Map19D3NCBI
cM Map1956.52NCBI
Fam204a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543122,920,817 - 22,942,165 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543122,920,076 - 22,947,959 (-)NCBIChiLan1.0ChiLan1.0
FAM204A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28130,171,654 - 130,207,565 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110130,164,096 - 130,212,903 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010114,870,818 - 114,916,884 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110118,307,273 - 118,339,838 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10118,307,058 - 118,339,838 (-)Ensemblpanpan1.1panPan2
FAM204A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12828,697,347 - 28,730,725 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2828,697,409 - 28,730,698 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2828,840,348 - 28,873,987 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02829,226,710 - 29,260,365 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2829,224,196 - 29,260,917 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12828,786,904 - 28,820,533 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02828,802,226 - 28,835,875 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02828,997,532 - 29,031,177 (-)NCBIUU_Cfam_GSD_1.0
Fam204a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721317,582,047 - 17,613,953 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364867,945,154 - 7,980,007 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364867,947,350 - 7,979,167 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAM204A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14128,365,916 - 128,402,560 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114128,366,152 - 128,402,587 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214139,880,728 - 139,917,161 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FAM204A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19111,112,988 - 111,145,411 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9111,112,027 - 111,145,771 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604872,375,858 - 72,408,591 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fam204a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473728,372,668 - 28,401,806 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fam204a
103 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:559
Count of miRNA genes:273
Interacting mature miRNAs:335
Transcripts:ENSRNOT00000013031
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
1549910Bw54Body weight QTL 540.05body mass (VT:0001259)body weight (CMO:0000012)1214647894259647894Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1214647894259647894Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1222363780260522016Rat
631690Scl5Serum cholesterol level QTL 52.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1236125214260522016Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1224054293260122809Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1225126575260522016Rat
7387289Uae45Urinary albumin excretion QTL 452.860.0021urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1223262787260522016Rat
10053715Scort24Serum corticosterone level QTL 242.130.0088blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1221414816260522016Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1224054293260122809Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1221264111259647894Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1223201027260522016Rat
1581544Rf52Renal function QTL 520.05urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)1232156370259647894Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
631837Niddm35Non-insulin dependent diabetes mellitus QTL 350.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1238699859259647894Rat
631836Stl31Serum triglyceride level QTL 314.645e-06blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1237147813260522016Rat
631536Lnnr2Liver neoplastic nodule remodeling QTL 22.90.0005liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)1233948574260522016Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1224569538260122809Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1216255568260522016Rat
737975Bw122Body weight QTL 1229.110.005body mass (VT:0001259)body weight (CMO:0000012)1258843780260122809Rat
1358890Bp259Blood pressure QTL 2593.06arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1210702053260522016Rat
1300108Rf8Renal function QTL 83.75renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1228581588259647894Rat

Markers in Region
RH143414  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21259,338,687 - 259,339,269 (+)MAPPERmRatBN7.2
Rnor_6.01281,348,797 - 281,349,378NCBIRnor6.0
Rnor_5.01288,702,500 - 288,703,081UniSTSRnor5.0
Celera1254,986,580 - 254,987,161UniSTS
Cytogenetic Map1q55UniSTS
RH141671  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21259,339,048 - 259,339,230 (+)MAPPERmRatBN7.2
Rnor_6.01281,349,158 - 281,349,339NCBIRnor6.0
Rnor_5.01288,702,861 - 288,703,042UniSTSRnor5.0
Celera1254,986,941 - 254,987,122UniSTS
RH 3.4 Map11704.2UniSTS
Cytogenetic Map1q55UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000013031   ⟹   ENSRNOP00000013031
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1259,337,709 - 259,367,077 (-)Ensembl
Rnor_6.0 Ensembl1281,347,536 - 281,376,834 (-)Ensembl
RefSeq Acc Id: NM_001107448   ⟹   NP_001100918
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81269,323,473 - 269,352,772 (-)NCBI
mRatBN7.21259,337,427 - 259,366,726 (-)NCBI
Rnor_6.01281,347,536 - 281,376,834 (-)NCBI
Rnor_5.01288,697,398 - 288,730,537 (-)NCBI
RGSC_v3.41266,749,513 - 266,779,356 (-)RGD
Celera1254,985,319 - 255,014,612 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001100918   ⟸   NM_001107448
- UniProtKB: D4A037 (UniProtKB/TrEMBL),   A6JI98 (UniProtKB/TrEMBL),   A6JI97 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000013031   ⟸   ENSRNOT00000013031

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A037-F1-model_v2 AlphaFold D4A037 1-238 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305500 AgrOrtholog
BioCyc Gene G2FUF-55233 BioCyc
Ensembl Genes ENSRNOG00000009830 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013031.7 UniProtKB/TrEMBL
InterPro FAM204A UniProtKB/TrEMBL
KEGG Report rno:308004 UniProtKB/TrEMBL
NCBI Gene 308004 ENTREZGENE
PANTHER PROTEIN FAM204A UniProtKB/TrEMBL
  PTHR14386 UniProtKB/TrEMBL
PhenoGen Fam204a PhenoGen
RatGTEx ENSRNOG00000009830 RatGTEx
UniProt A6JI97 ENTREZGENE, UniProtKB/TrEMBL
  A6JI98 ENTREZGENE, UniProtKB/TrEMBL
  D4A037 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-01 Fam204a  family with sequence similarity 204, member A  RGD1305500  similar to hypothetical protein FLJ13188  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1305500  similar to hypothetical protein FLJ13188   RGD1305500_predicted  similar to hypothetical protein FLJ13188 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1305500_predicted  similar to hypothetical protein FLJ13188 (predicted)  LOC308004_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC308004_predicted  similar to hypothetical protein FLJ13188 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL