L3mbtl3 (L3MBTL histone methyl-lysine binding protein 3) - Rat Genome Database

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Gene: L3mbtl3 (L3MBTL histone methyl-lysine binding protein 3) Rattus norvegicus
Analyze
Symbol: L3mbtl3
Name: L3MBTL histone methyl-lysine binding protein 3
RGD ID: 1305474
Description: Predicted to enable chromatin binding activity; identical protein binding activity; and methylation-dependent protein binding activity. Predicted to be involved in negative regulation of DNA-templated transcription; positive regulation of ubiquitin-dependent protein catabolic process; and regulation of DNA methylation-dependent heterochromatin formation. Predicted to act upstream of or within myeloid cell differentiation and regulation of ubiquitin-dependent protein catabolic process. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in nucleus. Orthologous to human L3MBTL3 (L3MBTL histone methyl-lysine binding protein 3); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: l(3)mbt-like 3; l(3)mbt-like 3 (Drosophila); L3MBTL3, histone methyl-lysine binding protein; lethal(3)malignant brain tumor-like protein 3; LOC309550
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2118,988,763 - 19,089,247 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl118,990,618 - 19,089,263 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0119,998,776 - 20,097,298 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl120,022,793 - 20,097,099 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0121,485,938 - 21,584,635 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4119,444,845 - 19,545,412 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1119,469,790 - 19,543,825 (+)NCBI
Celera117,383,083 - 17,480,930 (+)NCBICelera
Cytogenetic Map1p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleolus  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15889154   PMID:21516116   PMID:25416956   PMID:31515488  


Genomics

Comparative Map Data
L3mbtl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2118,988,763 - 19,089,247 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl118,990,618 - 19,089,263 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0119,998,776 - 20,097,298 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl120,022,793 - 20,097,099 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0121,485,938 - 21,584,635 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4119,444,845 - 19,545,412 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1119,469,790 - 19,543,825 (+)NCBI
Celera117,383,083 - 17,480,930 (+)NCBICelera
Cytogenetic Map1p12NCBI
L3MBTL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386130,018,581 - 130,141,438 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl6130,013,699 - 130,141,449 (+)EnsemblGRCh38hg38GRCh38
GRCh376130,339,726 - 130,462,583 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366130,381,427 - 130,504,278 (+)NCBINCBI36Build 36hg18NCBI36
Celera6131,086,140 - 131,209,005 (+)NCBICelera
Cytogenetic Map6q23.1NCBI
HuRef6127,920,637 - 128,043,565 (+)NCBIHuRef
CHM1_16130,603,269 - 130,725,909 (+)NCBICHM1_1
T2T-CHM13v2.06131,213,372 - 131,336,219 (+)NCBIT2T-CHM13v2.0
L3mbtl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391026,150,361 - 26,252,426 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1026,150,366 - 26,251,967 (-)EnsemblGRCm39 Ensembl
GRCm381026,274,461 - 26,376,036 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1026,274,468 - 26,375,971 (-)EnsemblGRCm38mm10GRCm38
MGSCv371025,995,258 - 26,094,991 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361025,964,868 - 26,064,601 (-)NCBIMGSCv36mm8
Celera1027,193,880 - 27,270,781 (-)NCBICelera
Cytogenetic Map10A4NCBI
L3mbtl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543610,920,075 - 11,013,520 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543610,900,521 - 11,014,259 (+)NCBIChiLan1.0ChiLan1.0
L3MBTL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16131,922,749 - 132,045,708 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6131,922,967 - 132,045,708 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06127,814,847 - 127,938,220 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
L3MBTL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1168,538,014 - 68,655,173 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl168,540,051 - 68,654,414 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha169,285,438 - 69,406,207 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0168,750,223 - 68,871,355 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl168,750,220 - 68,871,355 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1168,672,285 - 68,792,952 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0168,453,457 - 68,574,266 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0169,099,478 - 69,220,430 (+)NCBIUU_Cfam_GSD_1.0
L3mbtl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946118,663,924 - 118,751,667 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367901,212,536 - 1,298,566 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049367901,210,842 - 1,298,577 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
L3MBTL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl133,198,301 - 33,319,399 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1133,198,295 - 33,319,477 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2136,632,452 - 36,730,862 (-)NCBISscrofa10.2Sscrofa10.2susScr3
L3MBTL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11343,428,693 - 43,554,996 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1343,428,694 - 43,554,972 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604015,565,415 - 15,687,873 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
L3mbtl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247534,326,748 - 4,414,957 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247534,304,787 - 4,415,684 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in L3mbtl3
963 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:173
Count of miRNA genes:95
Interacting mature miRNAs:102
Transcripts:ENSRNOT00000015730, ENSRNOT00000061404
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1124744506Rat
2298546Neuinf4Neuroinflammation QTL 45.1nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1128736750Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1132356093Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1132356093Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)1132356093Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)150910843284926Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)150910843284926Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1224439043433040Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1592587724697545Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)11148148232355910Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)11532110019121980Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11543162149361612Rat
5684999Bss102Bone structure and strength QTL 1025.50.00000072tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11543162149361612Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11620621049268520Rat

Markers in Region
BF410282  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2118,991,731 - 18,991,922 (+)MAPPERmRatBN7.2
Rnor_6.0120,000,842 - 20,001,032NCBIRnor6.0
Rnor_5.0121,488,734 - 21,488,924UniSTSRnor5.0
RGSC_v3.4119,447,182 - 19,447,372UniSTSRGSC3.4
Celera117,383,437 - 17,383,627UniSTS
RH 3.4 Map1178.9UniSTS
Cytogenetic Map1p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 18 21 6 19 6 65 22 34 11
Low 1 25 36 35 35 8 11 9 13 7 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003748666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003753137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000061404   ⟹   ENSRNOP00000058121
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl118,992,651 - 19,089,263 (+)Ensembl
Rnor_6.0 Ensembl120,022,793 - 20,097,099 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000107555   ⟹   ENSRNOP00000092290
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl118,990,756 - 19,089,263 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118212   ⟹   ENSRNOP00000083485
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl118,990,618 - 19,089,263 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118227   ⟹   ENSRNOP00000090170
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl118,990,756 - 19,089,263 (+)Ensembl
RefSeq Acc Id: XM_003748666   ⟹   XP_003748714
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2118,990,613 - 19,089,247 (+)NCBI
Rnor_6.0119,999,759 - 20,097,298 (+)NCBI
Rnor_5.0121,485,938 - 21,584,635 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006227695   ⟹   XP_006227757
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2118,988,844 - 19,089,247 (+)NCBI
Rnor_6.0119,998,778 - 20,097,298 (+)NCBI
Rnor_5.0121,485,938 - 21,584,635 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006227696   ⟹   XP_006227758
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2118,988,763 - 19,089,247 (+)NCBI
Rnor_6.0119,998,776 - 20,097,298 (+)NCBI
Rnor_5.0121,485,938 - 21,584,635 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006227697   ⟹   XP_006227759
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2118,990,613 - 19,089,247 (+)NCBI
Rnor_6.0119,999,759 - 20,097,298 (+)NCBI
Rnor_5.0121,485,938 - 21,584,635 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006227699   ⟹   XP_006227761
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2119,013,784 - 19,089,247 (+)NCBI
Rnor_6.0120,022,823 - 20,097,298 (+)NCBI
Rnor_5.0121,485,938 - 21,584,635 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039098994   ⟹   XP_038954922
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2118,990,613 - 19,089,247 (+)NCBI
RefSeq Acc Id: XM_039098995   ⟹   XP_038954923
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2118,988,976 - 19,089,247 (+)NCBI
RefSeq Acc Id: XM_039098996   ⟹   XP_038954924
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2118,988,976 - 19,089,247 (+)NCBI
RefSeq Acc Id: XM_039098998   ⟹   XP_038954926
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2118,988,848 - 19,089,247 (+)NCBI
RefSeq Acc Id: XM_039099000   ⟹   XP_038954928
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2118,988,976 - 19,089,247 (+)NCBI
RefSeq Acc Id: XM_039099003   ⟹   XP_038954931
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2118,990,614 - 19,089,247 (+)NCBI
RefSeq Acc Id: XM_039099013   ⟹   XP_038954941
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2119,013,784 - 19,089,247 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_003748714   ⟸   XM_003748666
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZZG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227757   ⟸   XM_006227695
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZZG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227758   ⟸   XM_006227696
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZZG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227759   ⟸   XM_006227697
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZZG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227761   ⟸   XM_006227699
- Peptide Label: isoform X3
- UniProtKB: D3ZJT9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000058121   ⟸   ENSRNOT00000061404
RefSeq Acc Id: XP_038954926   ⟸   XM_039098998
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZZG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954924   ⟸   XM_039098996
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZZG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954923   ⟸   XM_039098995
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZZG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954928   ⟸   XM_039099000
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZZG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954922   ⟸   XM_039098994
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZZG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954931   ⟸   XM_039099003
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AH98 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954941   ⟸   XM_039099013
- Peptide Label: isoform X4
RefSeq Acc Id: ENSRNOP00000092290   ⟸   ENSRNOT00000107555
RefSeq Acc Id: ENSRNOP00000090170   ⟸   ENSRNOT00000118227
RefSeq Acc Id: ENSRNOP00000083485   ⟸   ENSRNOT00000118212
Protein Domains
SAM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZJT9-F1-model_v2 AlphaFold D3ZJT9 1-843 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305474 AgrOrtholog
BioCyc Gene G2FUF-62151 BioCyc
Ensembl Genes ENSRNOG00000011720 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000058121 ENTREZGENE
  ENSRNOP00000058121.3 UniProtKB/TrEMBL
  ENSRNOP00000083485 ENTREZGENE
  ENSRNOP00000083485.1 UniProtKB/TrEMBL
  ENSRNOP00000090170.1 UniProtKB/TrEMBL
  ENSRNOP00000092290 ENTREZGENE
  ENSRNOP00000092290.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000061404 ENTREZGENE
  ENSRNOT00000061404.5 UniProtKB/TrEMBL
  ENSRNOT00000107555 ENTREZGENE
  ENSRNOT00000107555.1 UniProtKB/TrEMBL
  ENSRNOT00000118212 ENTREZGENE
  ENSRNOT00000118212.1 UniProtKB/TrEMBL
  ENSRNOT00000118227.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
InterPro Mbt UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed UniProtKB/TrEMBL
  Znf_C2HC UniProtKB/TrEMBL
NCBI Gene 309550 ENTREZGENE
Pfam MBT UniProtKB/TrEMBL
  SAM_1 UniProtKB/TrEMBL
PhenoGen L3mbtl3 PhenoGen
PROSITE MBT UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/TrEMBL
  ZF_CCHHC UniProtKB/TrEMBL
SMART MBT UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
Superfamily-SCOP SAM_homology UniProtKB/TrEMBL
UniProt A0A8I5ZZG3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ADW7_RAT UniProtKB/TrEMBL
  A0A8I6AH98 ENTREZGENE, UniProtKB/TrEMBL
  D3ZJT9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-10 L3mbtl3  L3MBTL histone methyl-lysine binding protein 3  L3mbtl3  L3MBTL3, histone methyl-lysine binding protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-06-21 L3mbtl3  L3MBTL3, histone methyl-lysine binding protein  L3mbtl3  l(3)mbt-like 3 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 L3mbtl3  l(3)mbt-like 3 (Drosophila)   L3mbtl3_predicted  l(3)mbt-like 3 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 L3mbtl3_predicted  l(3)mbt-like 3 (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED