Emilin2 (elastin microfibril interfacer 2)

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Gene: Emilin2 (elastin microfibril interfacer 2) Rattus norvegicus

Analyze

Symbol:

Emilin2

Name:

elastin microfibril interfacer 2

RGD ID:

1305343

Description:

Predicted to be involved in several processes, including positive regulation of angiogenesis; positive regulation of blood coagulation; and positive regulation of platelet aggregation. Predicted to be located in extracellular region. Orthologous to human EMILIN2 (elastin microfibril interfacer 2); INTERACTS WITH amphetamine; DDT; diuron.

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

EMILIN-2; LOC316736

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	111,160,708 - 111,220,463 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	111,160,712 - 111,220,352 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	9	119,594,049 - 119,653,675 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	119,594,629 - 119,653,255 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	119,047,568 - 119,106,639 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	110,458,062 - 110,488,722 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	110,668,124 - 110,751,827 (-)	NCBI
Celera	9	108,289,680 - 108,349,263 (-)	NCBI		Celera
Cytogenetic Map	9	q38	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 18p deletion syndrome (ISO)

facioscapulohumeral muscular dystrophy 2 (ISO)

genetic disease (ISO)

holoprosencephaly 4 (ISO)

hypertrophic cardiomyopathy (ISO)

intellectual disability (ISO)

Majeed Syndrome (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

aflatoxin B1 (ISO)

amphetamine (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (ISO)

butanal (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

chloroprene (ISO)

choline (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

DDT (EXP)

dexamethasone (ISO)

diuron (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

folic acid (ISO)

gentamycin (EXP)

Heliotrine (EXP)

indole-3-methanol (EXP)

L-methionine (ISO)

lead(0) (ISO)

lead(2+) (ISO)

methapyrilene (ISO)

methylmercury chloride (ISO)

N-acetyl-L-cysteine (EXP)

N-nitrosodiethylamine (EXP)

nickel atom (ISO)

paracetamol (EXP)

pentanal (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenylmercury acetate (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

resveratrol (ISO)

rotenone (ISO)

SB 431542 (ISO)

senecionine (EXP)

Senkirkine (EXP)

silicon dioxide (ISO)

sodium arsenate (ISO)

sunitinib (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

thapsigargin (ISO)

thioacetamide (EXP)

trimellitic anhydride (ISO)

troglitazone (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of cell migration (ISO)

positive regulation of angiogenesis (ISO)

positive regulation of apoptotic process (ISO)

positive regulation of blood coagulation (ISO)

positive regulation of defense response to bacterium (ISO)

positive regulation of platelet aggregation (ISO)

Cellular Component

extracellular region (ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11278945	PMID:23658023	PMID:24006456

Genomics

Comparative Map Data

Emilin2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	111,160,708 - 111,220,463 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	111,160,712 - 111,220,352 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	9	119,594,049 - 119,653,675 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	119,594,629 - 119,653,255 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	119,047,568 - 119,106,639 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	110,458,062 - 110,488,722 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	110,668,124 - 110,751,827 (-)	NCBI
Celera	9	108,289,680 - 108,349,263 (-)	NCBI		Celera
Cytogenetic Map	9	q38	NCBI

EMILIN2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	2,846,232 - 2,916,003 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	18	2,847,006 - 2,916,003 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	18	2,847,004 - 2,916,001 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	2,837,028 - 2,904,090 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	18	2,837,027 - 2,904,088	NCBI
Celera	18	2,722,463 - 2,789,538 (+)	NCBI		Celera
Cytogenetic Map	18	p11.32-p11.31	NCBI
HuRef	18	2,808,350 - 2,875,373 (+)	NCBI		HuRef
CHM1_1	18	2,846,395 - 2,913,454 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	18	3,001,875 - 3,071,504 (+)	NCBI		T2T-CHM13v2.0

Emilin2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	71,559,167 - 71,618,551 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	71,559,167 - 71,618,973 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	71,252,172 - 71,311,556 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	71,252,172 - 71,311,978 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	71,601,516 - 71,660,305 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	71,154,355 - 71,216,323 (-)	NCBI		MGSCv36	mm8
Celera	17	75,520,092 - 75,581,836 (-)	NCBI		Celera
Cytogenetic Map	17	E1.3	NCBI

Emilin2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	7,508,159 - 7,519,977 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955402	7,507,674 - 7,519,978 (-)	NCBI	ChiLan1.0	ChiLan1.0

EMILIN2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	18	21,225,935 - 21,291,535 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	11,368,328 - 11,435,808 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	13,678,090 - 13,743,075 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	13,678,772 - 13,743,346 (-)	Ensembl	panpan1.1		panPan2

EMILIN2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	69,521,430 - 69,580,963 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	68,976,680 - 69,036,232 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	69,583,656 - 69,642,665 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	69,584,913 - 69,643,162 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	69,266,531 - 69,325,009 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	69,286,034 - 69,345,061 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	69,583,984 - 69,642,505 (+)	NCBI		UU_Cfam_GSD_1.0

Emilin2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	65,880,202 - 65,931,886 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936672	1,609,193 - 1,661,528 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936672	1,607,914 - 1,661,531 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EMILIN2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	103,730,626 - 103,786,927 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	103,730,618 - 103,786,921 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	96,739,144 - 96,792,557 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EMILIN2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	62,110,324 - 62,171,066 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	62,110,616 - 62,170,384 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	36,965,893 - 37,026,280 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Emilin2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624770	13,133,319 - 13,156,420 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Emilin2
416 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	50
Count of miRNA genes:	45
Interacting mature miRNAs:	50
Transcripts:	ENSRNOT00000056272
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
1354626	Bvd1	Brain ventricular dilatation QTL 1	3.73	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	9	75712843	111552878	Rat
7794784	Mcs31	Mammary carcinoma susceptibility QTL 31	2.98		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	9	77813894	111552878	Rat

Markers in Region

RH130840

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	111,160,755 - 111,160,952 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	119,594,096 - 119,594,292	NCBI	Rnor6.0
Rnor_5.0	9	119,047,615 - 119,047,811	UniSTS	Rnor5.0
RGSC_v3.4	9	110,458,112 - 110,458,308	UniSTS	RGSC3.4
Celera	9	108,289,727 - 108,289,923	UniSTS
RH 3.4 Map	9	868.3	UniSTS
Cytogenetic Map	9	q38	UniSTS

RH139954

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	111,243,577 - 111,243,758 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	119,675,883 - 119,676,063	NCBI	Rnor6.0
Rnor_5.0	9	119,129,078 - 119,129,258	UniSTS	Rnor5.0
RGSC_v3.4	9	110,536,120 - 110,536,300	UniSTS	RGSC3.4
Celera	9	108,372,104 - 108,372,284	UniSTS
RH 3.4 Map	9	869.3	UniSTS
Cytogenetic Map	9	q38	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		22			7		1	1	6		19	8	1
Low	3	21	52	36	12	36	7	10	68	35	22	3	7
Below cutoff			5	5		5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_017596881	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596882	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603772	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084817	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084818	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACYVU010000215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000056272 ⟹ ENSRNOP00000053111

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	111,160,712 - 111,220,352 (-)	Ensembl
Rnor_6.0 Ensembl	9	119,594,629 - 119,653,255 (-)	Ensembl

RefSeq Acc Id:

XM_017596881 ⟹ XP_017452370

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	111,160,708 - 111,220,445 (-)	NCBI
Rnor_6.0	9	119,594,879 - 119,653,675 (-)	NCBI

Sequence:

show sequence

TGCCGGAGAGAGGCCCCGGGGATCGAGGTGGGGACCGTCCGACGCTCTCTGCACTTCCGGAGGG
GCTGGGGGCGCGCTGTTTGGAAGGTGAGAGGCGGAGCTGCTGGCGTTTGGGAAGAGACCAAAGG
AATGTGTAATTGGAAAATCTGTAACCGAGACCCGGTTCCTAACCCTTTGGCTCTTTCCCCCCGA
GCCCCCTGTGGAGAGGCAAAGGGCCGAGAGATGGTGAAGGGAAGAGTCACGTTTCGGAGAGGGA
AGTGAAATAAAGAGGGCGGCACCCGGGGGGACCTGTGCGTCATTGAGGGACCTCGGAGCGGCCA
GTGCGGAGGCGTGGGGGCAAGGAGCCAGAGGGGCCGCCAAGCACCCGAGTCCGCTGCCCGTTCC
CGCGGCCCCGCAGTCTGCAGCCTTGTGGGGCTCAAGATGTGTCAGGAGACCCCGCCCCGACCCC
GAGCACCCAGCCGCTGGACGCCGGCCCTGCTGGCCCTGCTGGCCCTGGGCGGCGCGGGACTATG
CCACGCGAGCTCGCAGCCTGGGTACCACGCGCGGCCCAGTGCTAGGAACAAGAACTGGTGCGCC
TACATCGTGAATAAGAACGTAAGCTGCACGGTGCAGGAGGGAAGCGAGAGTTTTATTCAGGCTC
AGTACAACTGTCCCTGGAACCAGATGCCCTGTCCATCCGCTCTGGTGTATAGGGTAAACTTCAG
ACCCAGATTTGTCACTAGGTACAAGATAGTGACACAGTTGGAATGGAGATGCTGTCCAGGCTTT
AGAGGAGCAGACTGCCAAGAAGGTCCCAAAGACGCCATGAAGACTCCCCGGACTCCACCAGTTC
GACCAAGAAACAACCTGAAGAAAGCCACAGACACTGATCCAAGCCAAGTCTCACAGCCTAAGAA
AACTTTGTCACCAACAAATGCAACAGAACCAGGCCAGGTTGCAGATCCAAAGCAAGGTCCTCCA
GAATTTCAGCAAACCAAAGTCCAGGTGCTGGAGGAGAAGGTTGTCCGACTCACCAGGATGGTGC
TAGATCTCCAGTCGTCTGTGTCAGGCCTGAAGGAGAACCTCAAACACACCATCCAAGACGATGG
CAGCAAAGAGCCAGCCTCCTGGCTCGGTCCCCTGCACCCACAGCCAACCCCTGATGGCACCTTC
GCGGGGGACGCAGAGCCGAGCCAGCTTCCCGGAATCCTCAACAGCAAGGAATCTGGCATGAAGG
ACATCAAGTCTGAGCTGGCTGAGGTCAAAGACACATTGAAGACCAAGAGTGACAAGCTAGAAGA
GCTGGATGGGAAGGTGAAGGGCTATGAAGGGCAGCTCAAGCAGCTGCAGGAGGCTGCTCAGGGC
CCCACAGTCACCATGACAACCAACGAGCTGTTCCAAGCCTATGTGGATAGCAAGATAGATGCCC
TGAGAGAGGAGCTCATGGAGGGCATGGACCGGAAGCTGGCTGACCTGAAGAACACGTGCGAGTA
CAAGTTGGTGGGTCTCCAGCAGCAGTGTGATGACTATGGCAGCAGCTACCTCGGCGTGATAGAG
CTGATCGGAGAGAAGGAGGCGAGCCTGAAAAAGGACATCGCGGACCTCCGAGCACGGCTGCAGG
ACCCCACAGCCCAACCAAGCTGCTGCGACGGTCAAAAGAACGGCGATTTTGGCCCACAGATCAA
GACACTAGATCAGAAAATTGAGAGAGTTGCCGAGGCCACTAGGATGCTGAATGGACGGCTGGAC
AATGAATTCGACCGCCTCTCCTTTCCAGAGCCAGACGCAGACTTTGATGCGAGATGGAACGAGC
TGGACGCAAGGATCAACGTGACGGAGAAGAACGCAGAAGAGCATTGCTTTTACATCGAGGAGAC
TCTGCGGGGGGCCATCAACGGCGAAGTGGATGACTTGAGGAAGCTTCTCAATGAGAAAATCCAC
TCCCTGGAAGACCGTCTGGGAATCATTTTGCAAGTGACCAACGGCTCTGATTTGGAGTTGACAC
CTGTGGGCCCAGCCTTGTCAGGACAGCCAGGGCAGCCAGGGCAGCCAGGGGCAGAGAATGAGCA
ACTCCTAAGGGAGTTGAGCCGCCTGAAGGACAAAGTTCAAGTGGTTGAGGACATCTGCCTGCAG
AGCTTGCCCCATGGGATAGATGGAGCTTTGCCTAGTGGAGAAGACCTCACACATGTTGGCCTGA
GCCTTTTGGAATCCCTTAACGATACGATGCACAGGCAGTTCCAAGAAACAAGCCACAGCATCCA
GAAACTTCAAGAGGACTTCAGTGCCCTTTATTCTCAACTAAATCACTCAGAATATACAGGGACT
CGCTTGCCAAATGGAGTGAGTGACAGCATGGAAGCAAGTGGGTTTACTAAGACAGGGGAGCAAG
AGAGGACCGTGGGGACTGTCCCGTCTCCTGGGGGCCCTGTGGCTCCATGCTGTGGCCAGCTGGA
GGAGCGCTGGCAGAGGCTGCAGAACCAAGTGCTGGCTGAGCTAGACACATGCAAGGAGAGCGCT
CACGGGGTTCAAAGCGGGGTGTCTGCGGTCGAGGGCAGGGTGTCCCAGCTGGAGAAGACGTGCA
GCAGGTTGGACGCCATCTCAGGGAGTCTGCAGAGGATCAAGGAGGGGCTCGGGAAGCATGTGGG
CAGCCTGTGGAACTGTGTCCGGCAGATGAACGGGACACTCAGGTCACACTCCAGAGACATCTCT
GGCCTCAAGAATTCTGTGCAGCAATTCTACAGTCACGTCTTCCAGATTTCTACTGACTTGCAGG
ATCTGGTCAAGTTTCAGCCATCAGCAACAGAGGAACCCTTGGAAGCAACTCAGGGACCATCTGG
GAAGACCCCACTAGAATCCACCAGACCCTTGGAGGAGGCCCCCACTGAGCCACCGCGGCTGACC
CCACTGCCAGAACACCCTGCCGGACCACCACAGATAGGCCAGCGGCCAGTATTGCCCCAGAGGC
CCCTGCAGCCACCACCTTTGCCTGCCTGGCCTGGTCGCATGGGGTTGCCCGTCCTGCCTGGCTC
CAGTGGAGTCATCATGGAGACTGGAGAGGCTGGGCCTCCAGGCAGGATGGGCATGTCCGGAAGG
GGCCTGCCTCAGGGAGTGGATGGACAGATGGGGCAGGGGCCGATTCCTAGCTCGGAAGGCTACG
CAGGCGCACCAGGCTACCCCAAGTCACCTCCTGTAGCCACCCAGGGGTGTCGCTGCCTGCTCTG
GTGTCCTTTTCAGCTGGTCTTACCCAGAAGCCTTTTCCCAGTGATGGAGGTGTCGTCCTCTTTA
ATAAGGTGCTGGTGAATGATGGGGATGTATACAACCCCAGCACTGGGATCTTCACGGCACCGTA
TGATGGGCGCTACCTGATCACGGCCACCCTCACCCCGGAGAGGGATGCCTACGTGGAAGCGGTC
CTGTC

hide sequence

RefSeq Acc Id:

XM_039084817 ⟹ XP_038940745

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	111,160,708 - 111,220,463 (-)	NCBI

RefSeq Acc Id:

XM_039084818 ⟹ XP_038940746

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	111,160,708 - 111,213,088 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_017452370	(Get FASTA)	NCBI Sequence Viewer
	XP_038940745	(Get FASTA)	NCBI Sequence Viewer
	XP_038940746	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	XP_017452370 ⟸ XM_017596881
- Peptide Label:	isoform X1
- UniProtKB:	F1LXD8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MCQETPPRPRAPSRWTPALLALLALGGAGLCHASSQPGYHARPSARNKNWCAYIVNKNVSCTVQ EGSESFIQAQYNCPWNQMPCPSALVYRVNFRPRFVTRYKIVTQLEWRCCPGFRGADCQEGPKDA MKTPRTPPVRPRNNLKKATDTDPSQVSQPKKTLSPTNATEPGQVADPKQGPPEFQQTKVQVLEE KVVRLTRMVLDLQSSVSGLKENLKHTIQDDGSKEPASWLGPLHPQPTPDGTFAGDAEPSQLPGI LNSKESGMKDIKSELAEVKDTLKTKSDKLEELDGKVKGYEGQLKQLQEAAQGPTVTMTTNELFQ AYVDSKIDALREELMEGMDRKLADLKNTCEYKLVGLQQQCDDYGSSYLGVIELIGEKEASLKKD IADLRARLQDPTAQPSCCDGQKNGDFGPQIKTLDQKIERVAEATRMLNGRLDNEFDRLSFPEPD ADFDARWNELDARINVTEKNAEEHCFYIEETLRGAINGEVDDLRKLLNEKIHSLEDRLGIILQV TNGSDLELTPVGPALSGQPGQPGQPGAENEQLLRELSRLKDKVQVVEDICLQSLPHGIDGALPS GEDLTHVGLSLLESLNDTMHRQFQETSHSIQKLQEDFSALYSQLNHSEYTGTRLPNGVSDSMEA SGFTKTGEQERTVGTVPSPGGPVAPCCGQLEERWQRLQNQVLAELDTCKESAHGVQSGVSAVEG RVSQLEKTCSRLDAISGSLQRIKEGLGKHVGSLWNCVRQMNGTLRSHSRDISGLKNSVQQFYSH VFQISTDLQDLVKFQPSATEEPLEATQGPSGKTPLESTRPLEEAPTEPPRLTPLPEHPAGPPQI GQRPVLPQRPLQPPPLPAWPGRMGLPVLPGSSGVIMETGEAGPPGRMGMSGRGLPQGVDGQMGQ GPIPSSEGYAGAPGYPKSPPVATQGCRCLLWCPFQLVLPRSLFPVMEVSSSLIRCW hide sequence

RefSeq Acc Id:

ENSRNOP00000053111 ⟸ ENSRNOT00000056272

RefSeq Acc Id:	XP_038940745 ⟸ XM_039084817
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038940746 ⟸ XM_039084818
- Peptide Label:	isoform X3

Protein Domains

C1q EMI

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LXD8-F1-model_v2	AlphaFold	F1LXD8	1-1075	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696915

Promoter ID:

EPDNEW_R7438

Type:

single initiation site

Name:

Emilin2_1

Description:

elastin microfibril interfacer 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	119,653,329 - 119,653,389	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305343	AgrOrtholog
BioCyc Gene	G2FUF-26328	BioCyc
Ensembl Genes	ENSRNOG00000014837	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000053111	ENTREZGENE
	ENSRNOP00000053111.5	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000056272	ENTREZGENE
	ENSRNOT00000056272.5	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.1490	UniProtKB/TrEMBL
	2.60.120.40	UniProtKB/TrEMBL
InterPro	C1q	UniProtKB/TrEMBL
	EMI_domain	UniProtKB/TrEMBL
	Tumour_necrosis_fac-like_dom	UniProtKB/TrEMBL
NCBI Gene	316736	ENTREZGENE
PANTHER	EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER	UniProtKB/TrEMBL
	EMILIN-2	UniProtKB/TrEMBL
Pfam	C1q	UniProtKB/TrEMBL
	EMI	UniProtKB/TrEMBL
PhenoGen	Emilin2	PhenoGen
PROSITE	C1Q	UniProtKB/TrEMBL
	EMI	UniProtKB/TrEMBL
SMART	C1Q	UniProtKB/TrEMBL
Superfamily-SCOP	TNF_like	UniProtKB/TrEMBL
UniProt	F1LXD8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Emilin2	elastin microfibril interfacer 2	Emilin2_predicted	elastin microfibril interfacer 2 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Emilin2_predicted	elastin microfibril interfacer 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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