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Gene: Rfwd3 (ring finger and WD repeat domain 3) Rattus norvegicus
Symbol: Rfwd3
Name: ring finger and WD repeat domain 3
Description: Predicted to have MDM2/MDM4 family protein binding activity; p53 binding activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including DNA metabolic process; mitotic G1 DNA damage checkpoint; and regulation of DNA damage checkpoint. Predicted to colocalize with site of double-strand break. Human ortholog(s) of this gene implicated in Fanconi anemia. Orthologous to human RFWD3 (ring finger and WD repeat domain 3); INTERACTS WITH bisphenol A; cobalt dichloride; ochratoxin A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: E3 ubiquitin-protein ligase RFWD3-like; LOC361409; RGD1305243; similar to hypothetical protein FLJ34389
Homo sapiens (human) : RFWD3 (ring finger and WD repeat domain 3)  HGNC  Alliance
Mus musculus (house mouse) : Rfwd3 (ring finger and WD repeat domain 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rfwd3 (ring finger and WD repeat domain 3)
Pan paniscus (bonobo/pygmy chimpanzee) : RFWD3 (ring finger and WD repeat domain 3)
Canis lupus familiaris (dog) : RFWD3 (ring finger and WD repeat domain 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rfwd3 (ring finger and WD repeat domain 3)
Sus scrofa (pig) : RFWD3 (ring finger and WD repeat domain 3)
Chlorocebus sabaeus (African green monkey) : RFWD3 (ring finger and WD repeat domain 3)
Heterocephalus glaber (naked mole-rat) : Rfwd3 (ring finger and WD repeat domain 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01942,960,597 - 42,971,894 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1942,964,586 - 42,972,101 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01953,787,638 - 53,798,031 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01954,289,116 - 54,310,716 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41941,190,144 - 41,222,888 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11941,195,928 - 41,258,147 (-)NCBI
Celera1938,624,801 - 38,656,469 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Rfwd3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305243
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.