Pdia2 (protein disulfide isomerase family A, member 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Pdia2 (protein disulfide isomerase family A, member 2) Rattus norvegicus
Analyze
Symbol: Pdia2
Name: protein disulfide isomerase family A, member 2
RGD ID: 1305164
Description: ENCODES a protein that exhibits peptide disulfide oxidoreductase activity (ortholog); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; etoposide pharmacodynamics pathway; ASSOCIATED WITH bicuspid aortic valve disease (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bis(2-ethylhexyl) phthalate; bisphenol A
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC287164; Pdip; protein disulfide isomerase A2; protein disulfide isomerase associated 2; protein disulfide isomerase, pancreatic; protein disulfide-isomerase A2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21015,215,824 - 15,218,937 (-)NCBI
Rnor_5.01015,376,461 - 15,379,606 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,462,935 - 15,466,009 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11015,463,985 - 15,467,059 (-)NCBI
Celera1014,883,630 - 14,886,704 (-)NCBICelera
Cytogenetic Map10q12NCBI


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

Additional References at PubMed
PMID:16677074   PMID:19103594   PMID:19429457   PMID:25122773  


Genomics

Comparative Map Data
Pdia2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21015,215,824 - 15,218,937 (-)NCBI
Rnor_5.01015,376,461 - 15,379,606 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,462,935 - 15,466,009 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11015,463,985 - 15,467,059 (-)NCBI
Celera1014,883,630 - 14,886,704 (-)NCBICelera
Cytogenetic Map10q12NCBI
PDIA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl16283,164 - 287,215 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl16283,152 - 287,215 (+)EnsemblGRCh38hg38GRCh38
GRCh3816283,164 - 287,215 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3716333,164 - 337,215 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616273,119 - 277,210 (+)NCBINCBI36hg18NCBI36
Build 3416273,208 - 277,210NCBI
Celera16533,017 - 537,108 (+)NCBI
Cytogenetic Map16p13.3NCBI
HuRef16251,360 - 255,512 (+)NCBIHuRef
CHM1_116333,055 - 337,171 (+)NCBICHM1_1
Pdia2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391726,414,973 - 26,418,108 (-)NCBIGRCm39mm39
GRCm39 Ensembl1726,414,973 - 26,418,061 (-)Ensembl
GRCm381726,195,999 - 26,199,134 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1726,195,999 - 26,199,087 (-)EnsemblGRCm38mm10GRCm38
MGSCv371726,332,944 - 26,336,032 (-)NCBIGRCm37mm9NCBIm37
MGSCv361725,923,599 - 25,926,687 (-)NCBImm8
Celera1726,729,757 - 26,732,844 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
Pdia2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544216,898,635 - 16,901,799 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544216,898,563 - 16,901,867 (-)NCBIChiLan1.0ChiLan1.0
PDIA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.116273,692 - 278,014 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16273,764 - 277,914 (+)Ensemblpanpan1.1panPan2
PDIA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1640,218,566 - 40,221,924 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl640,218,550 - 40,231,402 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha641,482,205 - 41,485,425 (-)NCBI
ROS_Cfam_1.0640,560,945 - 40,564,168 (-)NCBI
UMICH_Zoey_3.1640,249,209 - 40,252,422 (-)NCBI
UNSW_CanFamBas_1.0640,210,283 - 40,213,487 (-)NCBI
UU_Cfam_GSD_1.0640,688,729 - 40,691,944 (-)NCBI
Pdia2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,536,174 - 112,539,335 (-)NCBI
SpeTri2.0NW_004936501634,034 - 637,177 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDIA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl341,394,197 - 41,398,348 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1341,394,267 - 41,397,547 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,030,474 - 41,033,683 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PDIA2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.15229,523 - 233,298 (+)NCBI
ChlSab1.1 Ensembl5229,607 - 233,200 (+)Ensembl
Pdia2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249131,135,498 - 1,138,900 (+)NCBI

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:99
Count of miRNA genes:87
Interacting mature miRNAs:94
Transcripts:ENSRNOT00000027726
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: NM_001105775   ⟹   NP_001099245
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21015,215,824 - 15,218,899 (-)NCBI
Rnor_5.01015,376,461 - 15,379,606 (-)NCBI
RGSC_v3.41015,462,935 - 15,466,009 (-)RGD
Celera1014,883,630 - 14,886,704 (-)RGD
Sequence:
RefSeq Acc Id: XM_039085368   ⟹   XP_038941296
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21015,215,826 - 15,218,937 (-)NCBI
RefSeq Acc Id: XM_039085369   ⟹   XP_038941297
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21015,215,826 - 15,218,835 (-)NCBI
RefSeq Acc Id: XM_039085370   ⟹   XP_038941298
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21015,215,826 - 15,217,562 (-)NCBI
RefSeq Acc Id: XR_005489718
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21015,215,824 - 15,218,937 (-)NCBI
RefSeq Acc Id: XR_005489719
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21015,216,792 - 15,218,937 (-)NCBI
RefSeq Acc Id: XR_005489720
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21015,216,527 - 15,218,937 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001099245 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941296 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941297 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941298 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM03998 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001099245   ⟸   NM_001105775
- Peptide Label: precursor
- Sequence:
RefSeq Acc Id: XP_038941296   ⟸   XM_039085368
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038941297   ⟸   XM_039085369
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038941298   ⟸   XM_039085370
- Peptide Label: isoform X3

Damaging Variants


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
10 15464549 15464550 A G snv BUF/N (KNAW)


Additional Information

Database Acc Id Source(s)
NCBI Gene 287164 ENTREZGENE
PhenoGen Pdia2 PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-10 Pdia2  protein disulfide isomerase family A, member 2  Pdia2  protein disulfide isomerase associated 2   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Pdia2  protein disulfide isomerase associated 2   Pdia2_predicted  protein disulfide isomerase associated 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Pdia2_predicted  protein disulfide isomerase associated 2 (predicted)  Pdip_predicted  protein disulfide isomerase, pancreatic (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Pdip_predicted  protein disulfide isomerase, pancreatic (predicted)      Symbol and Name status set to approved 70820 APPROVED