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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Pdia2 | Rat | 1,2-dichloroethane | increases expression | ISO | RGD:1622291 | 6480464 | ethylene dichloride results in increased expression of PDIA2 mRNA | CTD | PMID:28960355 | Pdia2 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of PDIA2 mRNA | CTD | PMID:24780913 | Pdia2 | Rat | acrylamide | decreases expression | ISO | RGD:1313029 | 6480464 | Acrylamide results in decreased expression of PDIA2 mRNA | CTD | PMID:32763439 | Pdia2 | Rat | antirheumatic drug | increases expression | ISO | RGD:1313029 | 6480464 | Antirheumatic Agents results in increased expression of PDIA2 mRNA | CTD | PMID:24449571 | Pdia2 | Rat | arsane | decreases expression | ISO | RGD:1313029 | 6480464 | Arsenic results in decreased expression of PDIA2 mRNA | CTD | PMID:36861143 | Pdia2 | Rat | arsenic atom | decreases expression | ISO | RGD:1313029 | 6480464 | Arsenic results in decreased expression of PDIA2 mRNA | CTD | PMID:36861143 | Pdia2 | Rat | benzo[a]pyrene | increases expression | ISO | RGD:1313029 | 6480464 | Benzo(a)pyrene results in increased expression of PDIA2 mRNA | CTD | PMID:22316170 | Pdia2 | Rat | benzo[a]pyrene | affects methylation | ISO | RGD:1313029 | 6480464 | Benzo(a)pyrene affects the methylation of PDIA2 5' UTR | CTD | PMID:27901495 | Pdia2 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | RGD:1313029 | 6480464 | Diethylhexyl Phthalate results in decreased expression of PDIA2 mRNA | CTD | PMID:31163220 | Pdia2 | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | RGD:1622291 | 6480464 | [Streptozocin co-treated with Diethylhexyl Phthalate] results in decreased expression of PDIA2 mRNA | CTD | PMID:31606821 | Pdia2 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in decreased expression of PDIA2 mRNA | CTD | PMID:29945229 | Pdia2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PDIA2 mRNA | CTD | PMID:25181051|PMID:30816183|PMID:32528016 | Pdia2 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of PDIA2 gene | CTD | PMID:28505145 | Pdia2 | Rat | cadmium atom | decreases expression | ISO | RGD:1313029 | 6480464 | Cadmium results in decreased expression of PDIA2 protein | CTD | PMID:16440303 | Pdia2 | Rat | cadmium dichloride | decreases expression | ISO | RGD:1313029 | 6480464 | Cadmium Chloride results in decreased expression of PDIA2 protein | CTD | PMID:16440303 | Pdia2 | Rat | carbon nanotube | affects expression | ISO | RGD:1622291 | 6480464 | Nanotubes, Carbon affects the expression of PDIA2 mRNA | CTD | PMID:25620056 | Pdia2 | Rat | carbon nanotube | decreases expression | ISO | RGD:1622291 | 6480464 | Nanotubes, Carbon analog results in decreased expression of PDIA2 mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681|PMID:25620056 | Pdia2 | Rat | chlordecone | increases expression | ISO | RGD:1622291 | 6480464 | Chlordecone results in increased expression of PDIA2 mRNA | CTD | PMID:33711761 | Pdia2 | Rat | chlorpromazine | increases expression | ISO | RGD:1313029 | 6480464 | Chlorpromazine analog results in increased expression of PDIA2 mRNA | CTD | PMID:15924885 | Pdia2 | Rat | ciguatoxin CTX1B | affects expression | ISO | RGD:1622291 | 6480464 | Ciguatoxins affects the expression of PDIA2 mRNA | CTD | PMID:18353800 | Pdia2 | Rat | cisplatin | multiple interactions | ISO | RGD:1313029 | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of PDIA2 mRNA | CTD | PMID:27392435 | Pdia2 | Rat | cisplatin | decreases expression | ISO | RGD:1313029 | 6480464 | Cisplatin results in decreased expression of PDIA2 mRNA | CTD | PMID:27392435 | Pdia2 | Rat | cyclosporin A | increases expression | ISO | RGD:1313029 | 6480464 | Cyclosporine results in increased expression of PDIA2 mRNA | CTD | PMID:20106945|PMID:21632981|PMID:25562108 | Pdia2 | Rat | ellagic acid | multiple interactions | EXP | | 6480464 | Ellagic Acid inhibits the reaction [Rotenone results in increased nitrosation of and results in decreased more ... | CTD | PMID:25247703 | Pdia2 | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of PDIA2 gene | CTD | PMID:22079235 | Pdia2 | Rat | ketamine | decreases expression | EXP | | 6480464 | Ketamine results in decreased expression of PDIA2 mRNA | CTD | PMID:20080153 | Pdia2 | Rat | L-ascorbic acid | decreases expression | ISO | RGD:1313029 | 6480464 | Ascorbic Acid results in decreased expression of PDIA2 mRNA | CTD | PMID:19197388 | Pdia2 | Rat | lactacystin | increases expression | ISO | RGD:1313029 | 6480464 | lactacystin results in increased expression of PDIA2 mRNA; lactacystin results in increased expression of PDIA2 more ... | CTD | PMID:15353226 | Pdia2 | Rat | lipopolysaccharide | affects localization | ISO | RGD:1622291 | 6480464 | Lipopolysaccharides affects the localization of PDIA2 protein | CTD | PMID:17475668 | Pdia2 | Rat | lipopolysaccharide | multiple interactions | ISO | RGD:1622291 | 6480464 | Vaticanol B inhibits the reaction [Lipopolysaccharides affects the localization of PDIA2 protein] | CTD | PMID:17475668 | Pdia2 | Rat | malathion | decreases expression | ISO | RGD:1313029 | 6480464 | Malathion results in decreased expression of PDIA2 mRNA | CTD | PMID:37047231 | Pdia2 | Rat | N-methyl-4-phenylpyridinium | increases expression | ISO | RGD:1313029 | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of PDIA2 mRNA; 1-Methyl-4-phenylpyridinium results in increased expression of PDIA2 more ... | CTD | PMID:15353226 | Pdia2 | Rat | potassium dichromate | increases expression | ISO | RGD:1622291 | 6480464 | Potassium Dichromate results in increased expression of PDIA2 mRNA | CTD | PMID:23608068 | Pdia2 | Rat | resveratrol | multiple interactions | ISO | RGD:1313029 | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of PDIA2 mRNA | CTD | PMID:23557933 | Pdia2 | Rat | rotenone | multiple interactions | EXP | | 6480464 | Ellagic Acid inhibits the reaction [Rotenone results in increased nitrosation of and results in decreased more ... | CTD | PMID:25247703 | Pdia2 | Rat | senecionine | decreases expression | ISO | RGD:1622291 | 6480464 | senecionine results in decreased expression of PDIA2 protein | CTD | PMID:35357534 | Pdia2 | Rat | sodium arsenite | decreases expression | ISO | RGD:1313029 | 6480464 | sodium arsenite results in decreased expression of PDIA2 protein | CTD | PMID:19294697 | Pdia2 | Rat | sodium dichromate | decreases expression | EXP | | 6480464 | sodium bichromate results in decreased expression of PDIA2 mRNA | CTD | PMID:22561333 | Pdia2 | Rat | streptozocin | increases expression | ISO | RGD:1622291 | 6480464 | Streptozocin results in increased expression of PDIA2 mRNA | CTD | PMID:31606821 | Pdia2 | Rat | streptozocin | multiple interactions | ISO | RGD:1622291 | 6480464 | [Streptozocin co-treated with Diethylhexyl Phthalate] results in decreased expression of PDIA2 mRNA | CTD | PMID:31606821 | Pdia2 | Rat | tetraphene | increases expression | ISO | RGD:1622291 | 6480464 | benz(a)anthracene results in increased expression of PDIA2 mRNA | CTD | PMID:26377693 | Pdia2 | Rat | titanium dioxide | increases expression | ISO | RGD:1622291 | 6480464 | titanium dioxide results in increased expression of PDIA2 mRNA | CTD | PMID:35295148 | Pdia2 | Rat | triclosan | increases expression | ISO | RGD:1313029 | 6480464 | Triclosan results in increased expression of PDIA2 mRNA | CTD | PMID:30510588 | Pdia2 | Rat | tunicamycin | decreases expression | ISO | RGD:1622291 | 6480464 | Tunicamycin results in decreased expression of PDIA2 mRNA | CTD | PMID:17127020 | Pdia2 | Rat | valproic acid | increases methylation | ISO | RGD:1313029 | 6480464 | Valproic Acid results in increased methylation of PDIA2 gene | CTD | PMID:29154799 | Pdia2 | Rat | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of PDIA2 mRNA | CTD | PMID:29427782 | |