Marchf1 (membrane associated ring-CH-type finger 1) - Rat Genome Database
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Gene: Marchf1 (membrane associated ring-CH-type finger 1) Rattus norvegicus
Analyze
Symbol: Marchf1
Name: membrane associated ring-CH-type finger 1
RGD ID: 1305148
Description: Predicted to have MHC protein binding activity and ubiquitin protein ligase activity. Predicted to be involved in antigen processing and presentation of peptide antigen via MHC class II; immune response; and protein polyubiquitination. Predicted to localize to bounding membrane of organelle; endoplasmic reticulum membrane; and plasma membrane. Orthologous to human MARCHF1 (membrane associated ring-CH-type finger 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E3 ubiquitin-protein ligase MARCH1; E3 ubiquitin-protein ligase MARCHF1; LOC361135; March1; membrane-associated ring finger (C3HC4) 1; membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase; RGD1305148; similar to hypothetical protein FLJ20668
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21623,255,554 - 24,114,290 (-)NCBI
Rnor_6.0 Ensembl1625,001,666 - 25,192,675 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01624,998,709 - 25,856,327 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01624,882,375 - 25,407,999 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41624,971,361 - 25,496,590 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11624,971,358 - 25,055,466 (-)NCBI
Celera1623,375,326 - 23,888,905 (-)NCBICelera
Cytogenetic Map16p14-p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:14722266   PMID:17255932   PMID:18305173   PMID:18389477   PMID:19117940   PMID:19880452   PMID:19917682   PMID:27577745  


Genomics

Comparative Map Data
Marchf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21623,255,554 - 24,114,290 (-)NCBI
Rnor_6.0 Ensembl1625,001,666 - 25,192,675 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01624,998,709 - 25,856,327 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01624,882,375 - 25,407,999 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41624,971,361 - 25,496,590 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11624,971,358 - 25,055,466 (-)NCBI
Celera1623,375,326 - 23,888,905 (-)NCBICelera
Cytogenetic Map16p14-p13NCBI
MARCHF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4163,524,298 - 164,384,050 (-)EnsemblGRCh38hg38GRCh38
GRCh384163,524,298 - 164,384,050 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh374164,445,450 - 165,304,669 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364164,668,499 - 164,754,226 (-)NCBINCBI36hg18NCBI36
Build 344164,806,653 - 164,892,381NCBI
Celera4161,777,720 - 162,636,895 (-)NCBI
Cytogenetic Map4q32.2-q32.3NCBI
HuRef4160,199,325 - 161,058,221 (-)NCBIHuRef
CHM1_14164,421,900 - 165,280,873 (-)NCBICHM1_1
Marchf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39866,070,550 - 66,925,761 (+)NCBIGRCm39mm39
GRCm39 Ensembl866,070,552 - 66,924,289 (+)Ensembl
GRCm38865,618,009 - 66,472,841 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl865,617,900 - 66,471,637 (+)EnsemblGRCm38mm10GRCm38
MGSCv37868,141,939 - 68,995,536 (+)NCBIGRCm37mm9NCBIm37
MGSCv36868,547,514 - 69,399,416 (+)NCBImm8
Celera868,174,462 - 69,027,711 (+)NCBICelera
Cytogenetic Map8B3.1NCBI
Marchf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540341,060,246 - 41,484,734 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540341,187,039 - 41,484,734 (+)NCBIChiLan1.0ChiLan1.0
MARCHF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14167,579,850 - 168,692,736 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4167,583,874 - 168,153,648 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04155,791,599 - 156,639,456 (-)NCBIMhudiblu_PPA_v0panPan3
MARCHF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1559,753,216 - 60,036,060 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11559,753,597 - 60,279,692 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Marchf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365551,810,896 - 2,097,870 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MARCHF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl852,375,510 - 52,951,031 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1852,375,510 - 52,951,031 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2855,502,841 - 55,523,454 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MARCHF1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17109,978,620 - 110,783,623 (-)NCBI
ChlSab1.1 Ensembl7109,979,056 - 110,063,661 (-)Ensembl
Marchf1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475812,528,242 - 13,321,851 (+)NCBI

Position Markers
D16Got26  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01625,431,274 - 25,431,449NCBIRnor6.0
Rnor_5.01625,314,487 - 25,314,662UniSTSRnor5.0
RGSC_v3.41625,403,389 - 25,403,562RGDRGSC3.4
RGSC_v3.41625,403,387 - 25,403,562UniSTSRGSC3.4
RGSC_v3.11625,403,387 - 25,403,560RGD
Celera1623,795,727 - 23,795,902UniSTS
RH 3.4 Map16286.9RGD
RH 3.4 Map16286.9UniSTS
RH 2.0 Map16329.9RGD
Cytogenetic Map16p14-p13UniSTS
RH144480  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01625,353,878 - 25,354,009NCBIRnor6.0
Rnor_5.01625,237,091 - 25,237,222UniSTSRnor5.0
RGSC_v3.41625,324,990 - 25,325,121UniSTSRGSC3.4
Celera1623,718,102 - 23,718,233UniSTS
RH 3.4 Map16285.3UniSTS
Cytogenetic Map16p14-p13UniSTS
BI301985  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01625,140,824 - 25,141,015NCBIRnor6.0
Rnor_5.01625,024,490 - 25,024,681UniSTSRnor5.0
RGSC_v3.41625,110,842 - 25,111,033UniSTSRGSC3.4
Celera1623,513,636 - 23,513,827UniSTS
RH 3.4 Map16290.3UniSTS
Cytogenetic Map16p14-p13UniSTS
RH138482  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01624,999,993 - 25,000,139NCBIRnor6.0
Rnor_6.01626,077,239 - 26,077,385NCBIRnor6.0
Rnor_5.01625,962,945 - 25,963,091UniSTSRnor5.0
Rnor_5.01624,883,659 - 24,883,805UniSTSRnor5.0
RGSC_v3.41624,969,688 - 24,969,834UniSTSRGSC3.4
Celera1623,373,653 - 23,373,799UniSTS
RH 3.4 Map16281.2UniSTS
Cytogenetic Map16p14-p13UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16127556253Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16127556253Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16127556253Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16131816439Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16133160624Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16134465490Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16141240937Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16141240937Rat
631561Hcuc2Hepatic copper content QTL 22.8hepatic copper amount (VT:0003065)liver total copper weight (CMO:0001507)16141240957Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)1624459345244593Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)16109005486162972Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16134074146340741Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)16155018749247447Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)16155018763210301Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16155018763210301Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)16155018763210301Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)16155018763210301Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16172829746728297Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16413635545905331Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16501380245905331Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16501380245905331Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16501380245905331Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16501380250013802Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16501380250169318Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16501380252144919Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16501380264012784Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161939818770590230Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161939818770590230Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161939818770590230Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161939818770590230Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)162075555680316424Rat
2302057Pia29Pristane induced arthritis QTL 293.60.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)162484654169846541Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:146
Count of miRNA genes:112
Interacting mature miRNAs:122
Transcripts:ENSRNOT00000032289
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 1 12 36 1
Low 17 34 19 7 19 4 4 32 10 8 10 4
Below cutoff 1 22 18 18 18 4 7 2 17 23 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000032289   ⟹   ENSRNOP00000038896
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1625,001,666 - 25,192,675 (-)Ensembl
RefSeq Acc Id: NM_001135838   ⟹   NP_001129310
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21623,259,647 - 23,781,405 (-)NCBI
Rnor_6.01625,001,666 - 25,524,786 (-)NCBI
Rnor_5.01624,882,375 - 25,407,999 (-)NCBI
RGSC_v3.41624,971,361 - 25,496,590 (-)RGD
Celera1623,375,326 - 23,888,905 (-)RGD
Sequence:
RefSeq Acc Id: XM_008771133   ⟹   XP_008769355
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01624,998,709 - 25,378,790 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008771134   ⟹   XP_008769356
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21623,255,554 - 24,114,274 (-)NCBI
Rnor_6.01624,998,709 - 25,378,795 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600175   ⟹   XP_017455664
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21623,255,554 - 23,781,400 (-)NCBI
Rnor_6.01624,998,709 - 25,378,797 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600176   ⟹   XP_017455665
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21623,255,554 - 24,114,290 (-)NCBI
Rnor_6.01624,998,709 - 25,378,800 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600177   ⟹   XP_017455666
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01624,998,709 - 25,525,449 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600178   ⟹   XP_017455667
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21623,255,554 - 23,790,939 (-)NCBI
Rnor_6.01624,998,709 - 25,534,395 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600179   ⟹   XP_017455668
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21623,255,554 - 24,114,286 (-)NCBI
Rnor_6.01624,998,709 - 25,856,327 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600180   ⟹   XP_017455669
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01624,998,709 - 25,116,613 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600181   ⟹   XP_017455670
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01624,998,709 - 25,525,285 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039094632   ⟹   XP_038950560
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21623,255,554 - 24,114,286 (-)NCBI
RefSeq Acc Id: XM_039094633   ⟹   XP_038950561
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21623,255,554 - 24,113,537 (-)NCBI
RefSeq Acc Id: XM_039094634   ⟹   XP_038950562
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21623,255,554 - 24,114,286 (-)NCBI
RefSeq Acc Id: XM_039094635   ⟹   XP_038950563
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21623,255,554 - 24,114,270 (-)NCBI
RefSeq Acc Id: XM_039094636   ⟹   XP_038950564
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21623,255,554 - 24,114,270 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001129310   ⟸   NM_001135838
- Sequence:
RefSeq Acc Id: XP_008769356   ⟸   XM_008771134
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008769355   ⟸   XM_008771133
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017455668   ⟸   XM_017600179
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017455667   ⟸   XM_017600178
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017455666   ⟸   XM_017600177
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017455670   ⟸   XM_017600181
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017455665   ⟸   XM_017600176
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017455664   ⟸   XM_017600175
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017455669   ⟸   XM_017600180
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSRNOP00000038896   ⟸   ENSRNOT00000032289
RefSeq Acc Id: XP_038950560   ⟸   XM_039094632
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038950562   ⟸   XM_039094634
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038950563   ⟸   XM_039094635
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038950564   ⟸   XM_039094636
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038950561   ⟸   XM_039094633
- Peptide Label: isoform X2
Protein Domains
RING-CH-type

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305148 AgrOrtholog
Ensembl Genes ENSRNOG00000026310 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000038896 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032289 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro Znf_RING-CH UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene 361135 ENTREZGENE
Pfam RINGv UniProtKB/TrEMBL
PhenoGen Marchf1 PhenoGen
PROSITE ZF_RING_CH UniProtKB/TrEMBL
SMART RINGv UniProtKB/TrEMBL
UniProt D4A6K8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-08 Marchf1  membrane associated ring-CH-type finger 1  March1  membrane associated ring-CH-type finger 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-12-02 March1  membrane associated ring-CH-type finger 1  March1  membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-05 March1  membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase  March1  membrane-associated ring finger (C3HC4) 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 March1  membrane-associated ring finger (C3HC4) 1   March1_predicted  membrane-associated ring finger (C3HC4) 1 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 March1_predicted  membrane-associated ring finger (C3HC4) 1 (predicted)  RGD1305148_predicted  similar to hypothetical protein FLJ20668 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1305148_predicted  similar to hypothetical protein FLJ20668 (predicted)  LOC361135_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC361135_predicted  similar to hypothetical protein FLJ20668 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL