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Gene: Rtkn2 (rhotekin 2) Rattus norvegicus

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Symbol:

Rtkn2

Name:

rhotekin 2

RGD ID:

1304834

Description:

Predicted to be involved in several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of cell population proliferation; and regulation of intracellular signal transduction. Predicted to be located in cytoplasm; nucleus; and plasma membrane. Orthologous to human RTKN2 (rhotekin 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,5-hexanedione; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC309729; pleckstrin homology domain containing, family K member 1; Plekhk1; rhotekin-2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RTKN2 (rhotekin 2)	HGNC	Ensembl, HomoloGene, NCBI, OrthoDB, Panther
Mus musculus (house mouse):	Rtkn2 (rhotekin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rtkn2 (rhotekin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RTKN2 (rhotekin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RTKN2 (rhotekin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rtkn2 (rhotekin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RTKN2 (rhotekin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RTKN2 (rhotekin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rtkn2 (rhotekin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	RTKN2 (rhotekin 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rtkn2 (rhotekin 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rtkn2a (rhotekin 2a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	C07B5.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rtkn2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	20,535,553 - 20,608,863 (-)	NCBI		GRCr8
mRatBN7.2	20	20,536,628 - 20,609,951 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	20,525,256 - 20,609,951 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	21,265,443 - 21,338,751 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	20,618,060 - 20,691,365 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	21,093,180 - 21,166,480 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	21,919,486 - 22,004,279 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	21,932,878 - 22,004,279 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	24,018,286 - 24,102,848 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	21,346,889 - 21,434,160 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	21,378,450 - 21,446,629 (-)	NCBI
Celera	20	21,888,821 - 21,973,490 (-)	NCBI		Celera
Cytogenetic Map	20	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant intellectual developmental disorder 70 (ISO)

interstitial lung disease 2 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dichloroethane (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,5-hexanedione (EXP)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

aflatoxin M1 (ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

butanal (ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

copper(II) sulfate (ISO)

dicrotophos (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

fonofos (ISO)

glyphosate (ISO)

leflunomide (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methamphetamine (ISO)

methapyrilene (ISO)

methotrexate (ISO)

methoxychlor (EXP)

methylmercury chloride (ISO)

N-Nitrosopyrrolidine (ISO)

nickel atom (ISO)

ozone (EXP,ISO)

paracetamol (EXP,ISO)

paraquat (EXP)

parathion (ISO)

perfluorooctanoic acid (ISO)

phenethyl isothiocyanate (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

terbufos (ISO)

testosterone (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

hemopoiesis (IBA,IEA,ISO)

negative regulation of intrinsic apoptotic signaling pathway (IEA,ISO)

positive regulation of cell population proliferation (IBA,IEA,ISO)

positive regulation of NF-kappaB transcription factor activity (ISO)

positive regulation of non-canonical NF-kappaB signal transduction (IEA,ISO)

signal transduction (IEA)

Cellular Component

cytoplasm (IEA,ISO)

nucleus (IEA,ISO)

plasma membrane (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11740862	PMID:15504364	PMID:26124677

Genomics

Comparative Map Data

Rtkn2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	20,535,553 - 20,608,863 (-)	NCBI		GRCr8
mRatBN7.2	20	20,536,628 - 20,609,951 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	20,525,256 - 20,609,951 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	21,265,443 - 21,338,751 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	20,618,060 - 20,691,365 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	21,093,180 - 21,166,480 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	21,919,486 - 22,004,279 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	21,932,878 - 22,004,279 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	24,018,286 - 24,102,848 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	21,346,889 - 21,434,160 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	21,378,450 - 21,446,629 (-)	NCBI
Celera	20	21,888,821 - 21,973,490 (-)	NCBI		Celera
Cytogenetic Map	20	p11	NCBI

RTKN2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	62,183,900 - 62,268,844 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	62,183,035 - 62,268,844 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	63,952,845 - 64,028,603 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	63,622,959 - 63,698,472 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	63,622,960 - 63,698,472	NCBI
Celera	10	57,220,086 - 57,295,600 (-)	NCBI		Celera
Cytogenetic Map	10	q21.2	NCBI
HuRef	10	57,942,866 - 58,018,390 (-)	NCBI		HuRef
CHM1_1	10	64,235,045 - 64,310,536 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	63,049,731 - 63,125,461 (-)	NCBI		T2T-CHM13v2.0

Rtkn2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	67,815,371 - 67,894,259 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	67,815,400 - 67,895,570 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	67,979,566 - 68,058,429 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	67,979,570 - 68,059,740 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	67,442,346 - 67,506,612 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	67,374,955 - 67,439,221 (+)	NCBI		MGSCv36	mm8
MGSCv36	10	68,030,495 - 68,095,230 (+)	NCBI		MGSCv36	mm8
Celera	10	69,075,420 - 69,142,823 (+)	NCBI		Celera
Cytogenetic Map	10	B5.1	NCBI
cM Map	10	35.06	NCBI

Rtkn2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	15,460,449 - 15,562,964 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955425	15,484,287 - 15,563,535 (-)	NCBI	ChiLan1.0	ChiLan1.0

RTKN2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	74,400,607 - 74,477,569 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	74,405,930 - 74,476,793 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	58,707,821 - 58,793,899 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	61,037,732 - 61,123,153 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	61,047,775 - 61,123,153 (-)	Ensembl	panpan1.1		panPan2

RTKN2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	14,165,569 - 14,245,088 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	14,176,134 - 14,312,414 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	14,376,885 - 14,462,826 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	14,428,740 - 14,508,664 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	14,433,943 - 14,575,888 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	14,417,236 - 14,491,394 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	14,537,079 - 14,616,879 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	14,897,636 - 14,971,810 (-)	NCBI		UU_Cfam_GSD_1.0

Rtkn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	66,837,666 - 66,910,953 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936614	923,977 - 995,343 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RTKN2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	65,686,725 - 65,775,201 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	65,686,718 - 65,861,385 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	70,813,516 - 70,848,892 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RTKN2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	69,014,351 - 69,095,476 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	69,014,782 - 69,092,353 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	29,898,995 - 29,978,197 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rtkn2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624791	1,471,058 - 1,539,763 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624791	1,470,830 - 1,544,565 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Rtkn2
360 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	325
Count of miRNA genes:	199
Interacting mature miRNAs:	244
Transcripts:	ENSRNOT00000068778
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4889610	Pancm3	Pancreatic morphology QTL 3	3.75	0.001	pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	20	17617832	47606836	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1530655	46530655	Rat
2317057	Aia27	Adjuvant induced arthritis QTL 27	2.83		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	20	2892597	26381954	Rat
7387283	Uae44	Urinary albumin excretion QTL 44		0.1712	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	20	1	26123605	Rat
4889870	Pur30	Proteinuria QTL 30	19	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	8042410	29322208	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600972	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1527842	46527842	Rat
1354642	Despr15	Despair related QTL 15		0.0027	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	20	1	24159021	Rat
1600382	Edcs3	Endometrial carcinoma susceptibility QTL3	3.5	0.003	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	20	1	25159026	Rat
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29191651	Rat
2303626	Vencon10	Ventilatory control QTL 10		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	20	19190721	54435887	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29191651	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29191651	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29191651	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29191651	Rat
7411652	Foco24	Food consumption QTL 24		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	11757515	54435887	Rat
2317851	Alcrsp22	Alcohol response QTL 22	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27339237	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	2606836	47606836	Rat
2317880	Alcrsp25	Alcohol response QTL 25	2.3		response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	17697550	54435887	Rat
1641893	Alcrsp7	Alcohol response QTL 7			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27339237	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578807	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600972	Rat
9590092	Insglur9	Insulin/glucose ratio QTL 9	18.38	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	20	11757515	54435887	Rat

Markers in Region

RH128980

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	20,536,752 - 20,536,906 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	21,931,014 - 21,931,167	NCBI	Rnor6.0
Rnor_5.0	20	24,029,731 - 24,029,884	UniSTS	Rnor5.0
Celera	20	21,900,311 - 21,900,464	UniSTS
Cytogenetic Map	20	p11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	10	49	113	87	86	55	25	55	6	212	96	93	44	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107625	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006256367	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008772883	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008772884	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098751	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098753	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098754	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000068778 ⟹ ENSRNOP00000060630

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	20,525,256 - 20,609,951 (-)	Ensembl
Rnor_6.0 Ensembl	20	21,932,878 - 22,004,279 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000086250 ⟹ ENSRNOP00000072047

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	20,525,256 - 20,609,951 (-)	Ensembl
Rnor_6.0 Ensembl	20	21,934,839 - 22,004,209 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093984 ⟹ ENSRNOP00000081437

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	20,525,256 - 20,558,495 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110488 ⟹ ENSRNOP00000083152

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	20,534,637 - 20,603,252 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118813 ⟹ ENSRNOP00000096702

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	20,534,637 - 20,609,951 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000120105 ⟹ ENSRNOP00000079187

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	20,525,256 - 20,558,495 (-)	Ensembl

RefSeq Acc Id:

NM_001107625 ⟹ NP_001101095

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	20,535,553 - 20,608,862 (-)	NCBI
mRatBN7.2	20	20,536,628 - 20,609,951 (-)	NCBI
Rnor_6.0	20	21,919,486 - 22,004,279 (-)	NCBI
Rnor_5.0	20	24,018,286 - 24,102,848 (-)	NCBI
RGSC_v3.4	20	21,346,889 - 21,434,160 (-)	RGD
Celera	20	21,888,821 - 21,973,490 (-)	RGD

Sequence:

show sequence

TGCTTAAGGCCGGCTGTAGCAGAGGGTCTGTGCAGAGTCCTCGGGTCTCGTGCTGTTCTAGAGA
CGGAGCGGACCCTAGTGCGCTTGCGCGGCGTCGTGGGCCGGGTTCCCCTGCAGCTCGGACTTGG
TACGGCCGAGCGGTTGGTGCGGTCTGCAGCTGCAGCCCCGGGGCGCGCTTTTCAAATCGTGGTT
GACGTGCGCCGAAATGGAAGGGCAGCTGCTGAGGGGCCTCGCCGCGCAGCAGGACTGCAGCATC
CAAGAGAAAATAGACTTAGAGATCCGAATGCGAGAAGGAATATGGAAACTGCTCTCCCTGAGTA
AAAAAAAAGACCAGGTTTTGCACGCAGTTAAGAACCTCATGGTCTGCAATGCTCGGATGCAGGT
GTACACGGCGGAGCTGCAGAAGTTAGAAGAGACTGCAAGTCAAACCGGAAGACGGTTAGTGCTG
GATGCGAGTTTAGAAACTAAAGAACAAGAACCCTGCAGAGGGAAGATCGCTCTGTCAGATATTC
GAATACCGTTAATGTGGAAAGACTCCGATCACTTCGGTCATAAGGAATGCACACAGCGCTTTGC
CATCTTTTGCTTATTCAGGATGGGAACCCAAGTGTTTGACACCGACATGATGATTGTGGACCAG
ACCGTCACAGATATATGTTTTGAAAACGTCACCATATTCAACGAAGCAGGACCAGACTTCCGGG
TAAAGATAGAGGTCTACAGCAGCAGCGCAGAGGAATCTTCCATAACCAACACCCCCAAAAAGCT
GGCTAAAAAGCTGAAGACGTCCATCAGCAAAGCTACGGGAAGGAAGATAAGTGCTGTGCTGCAG
GAGGAGGACCAGGAGGCGAGCCTGCTTGTCAGCTCCGTGGCAGGAGTGTTCCTTTTGGCTTCCC
TTGTATGGCAACCTATGCTGTCGGCTAGTGGCCCAGCCAGCCTGCATGGCTGAAGACGCATTTG
CAGGATTCCTTAATGAGCAGCAAACAGGAAAAGGTTTGGTTGGCTGGAGAAGGTTGTACTGTGC
TCTGAGAGGGGGTAAACTCCGCTGTTTTTATGGTCCAGAAGAAATTGAAGCCAAAGTGGAACCG
ACTCTGGTGATTCCTGTTGACAAGGAAACCAGGATCCAGGCCATGGAAAAGGATTCAAAGAAAA
TGCACTGCTTCTCCGTCCTCACCACGGCTGCTGGGCGAGCAGTGAGTCACATCTTTGCGGCTGA
CGGCCTAGGAGACTTTCAAGAATGGATGGACGCTTTCCGGCAGCACCGCTTTGATCTCAGCATT
GATTCACCTGTGAAACTCGAAAGCGTGACGGACATAATACAAAAAAAAATCGGAGAGACCAATG
GACAGTTCCTCATTGGTCGGGAGGAGGAATCCACAACACCCCCGTGGGCCTCAGTGTTTGATGG
CAGCCATGAGATGGTCATCCAGAAGAAAGTCTTGTCCCCAGCAGGCAAACCAGCACCGGATGGG
AAAAGGAAAAAGAGACGTGCTCCCCTCCCTCCTATGGATCAGCCTCCCTTCAGTGTAAAGACAC
AAGGTAGCATGGGTCAGTCCAAGGACAGCGAAGCCCAGGTCGGTGTCTCTGGGGCCCCATCTTC
AGATCGCAGACTGTCACCGCCTACGCATCACCTCCAGAAACCGGTGGCTGCCCCTCGCAAACTT
CTCCCCACCAGGAAAAGCAGTTCAGAGGACAGCGGGCCCACAGATGCTAAAACCAGTTTGGACG
GGAAGCCAGTGCCAGCTCCAAGGCAGAAATCCATCAGAGACATTCTGGACCCTCGATCGTGGCT
CCAAGCACAAGTGTAGGAAGCCTGTACTGTGTAAATCCAGCTGTAAGGCTCGGTCAGAGGCATT
GTGAGTGTAATGTTAGATAATTGTAGAGGTAAAGACCAGAGCAGTTTCCGGAAGCCATTAATAA
GTGGTTAGATACAGAAAAGCACCTTTAAATAGAGAATTGGATTTCCCCTTTACTTCTCCTTTCC
AGAATATCAATGGTTTCTCCCCACGGAACAAAAGAGGAAATTTCTAGACAATATCTTACTCGTT
GGAAGGGTTAATTTATTCCTAATTTTGTAGCAGGCAGTGGACAGGCAGCAGGCATTAAAAGCAT
TGATTTTTTTTTGGGGGGGGGGTAAAATGTCTTCAATACAAGCCACATTCTCATTGTGAGAACT
TTAATACTTAACGGAGTGCTTCAAAGGTTTTACTCAAACCACAAATTACAGAATCCACCCAAGG
AAATGTGTCCGGTCAGCTTTCTGGGATTCTCATCTAACAGTCCTCTGGATCCCTCCCCTCTGTT
GTTTAACTCAATGATCTATAGGGTTGACCTTTTTAAATTCCTGGGATACATTTTCGAATATTAA
ACCCTTTATCTTTAAAGGGAATTTGTAATCTGCTATTCAAAGTCATTTCTTTGATGAGCCCTGA
AATCCTGTTGACTTCACCGCTTGCAGTGAGGCCCACCCTTCTTAGGGAGTGAAGTGGATGTGAA
ATGTCCCCCTTCGTCCTGCTTGCCATAGGATGCTAATCTCCGTTTGTGGCCTCTGGAATTCAGG
GAGACAAGTCGCTGACTAATGCCTTAAATTTTTACTTAATACTTTAAAAGCAGATGGCAGATTC
AAAAAATTATCAGGAAGGTTGACCGCAGTAATCTTCAGAATTAATCCTTTTTCAATTTTTTAAT
TAGATTTTCCTTTTTTTTTTTTTTTTTGAGTAAGGACTGATGTCTGTTATTGATATTGTCTGAT
ATTGTGTTACTGATATTCATTCAGTAATCACATTGGCGTCATTTCCATAGGAGGTAATTTCCAT
AGCAACTAATCACAGTGACCCAAACAGGATTATAAATTGAATGGGGGGATAAATAGCAAGAGGA
TGAATATCTTAAACGGACAAAAAGAAAAATCCACTTTTTATAATAACCCCTTTTGTAAACAAGA
GTAGCGGAACAGTTTTAAAATGTCATCAGAATTTCCAAGCAAACTTCCCAGAGGGTATTTGCAC
CAGTTCTGAAAAGTCCAGGACCTCCCACGCCCTAACGGGTACCATAATCCATCACGCTGAAGGA
ATGAGTTCTGTCAATCTGGATGGGAACTACGCCCACGTAAAATGGCCAACCGAGCCTTCCGATT
TCTTGTACAAATTACAGCTGGAAGAATTTAAGGTGTGTGCGTGCGTGCATGCATGCGTGTGTGC
CTGTGCCTGTGCCTGTGCCTGTGCCTGTGCCTGTGCCTGTGCCTGTGCCTGTGTCTCTTCCTGG
AAACATTCTGAAGGAGTTGTGTTCTTAGCAGGCAGCTTTGAACCATGTCTGAAATCAGCCTCCT
TCCTTCTTGGAAAACCGGAGACTTTGGAAAGCCTACTCTGTCACCTGCCACAAGAGGCTTCCCG
GTGTTTACAGCTCCTCCAGTGAGTGGCAGCGAGATTGCAAAATTTGATTCTTTGTACTGCCTGA
TGAAATGTTCCAATCTTTGCAAAATCCCGTGTCAGCCAATCACATGCTCCAGATTGCCCGTACA
TGAAGTTACAAAATGCTACATGATGCAAAAGTTCAAGAGAGAGTCTTGGATACTATTGTGACAG
GACAAACTGTTCATGAACGTGACCGCACTGCAACCACCACCCCTTGTCAGCTTTTGGATTATGA
CCAAAAGCAATGGACATGTCACAGGACCAGGCTACTAAAGAGCCCTCTCCCCCTTTTAAGCACA
AAGCTGGGGAAGATTGCTGTCACTCCACGTGTACCAGAAAGGGCTTAAAATCCCACTGTCAGGA
AGAACAAGGAGTAAATGTTGGTTTTCAGATGAGAAGAGAAGAAAGCGGATATGTGAGAGGGGAG
CCCCGAGAGTCAGAGAGAAAACACACACCACTCGCATCCCAGAGATCTCATATCCTTGACTCCA
GTAGGGGCCCAACTCACATGCGAGCTCTAAGAGAGGACCCAGTACATTCGGCTAGAGTGGGTTT
CCATTGGAATCCTCTATAGCTAAAAAATAGCGGGCAGCCATTCAGAATCACTGATTGCTACTAA
AGTGGGACACGAATGGCCCATTATCAAACGTAGTAAGGTTTATGCTGTGCTATACACTTTAGGG
TTGGATTAAATCAGAAATATAAAACGCGTGTTTCCGGAAAATATAAGAGGCTATATCTAAATTG
AAGCTGAAAAAGAAGACTTACCATGGGCTACACACAAATTAATTACTATCTTCAAAGAATTACA
ATACTATCAAACATTCCTAGCACAAAATTATGCTGAACAAAATTTAATCTTTCTGTGACTGTTC
AAAAGAATTTAGGATCTTGTAACCCTCCCGGGACACTACCATTTTATAAATCGTACC

hide sequence

RefSeq Acc Id:

XM_006256367 ⟹ XP_006256429

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	20,535,553 - 20,608,863 (-)	NCBI
mRatBN7.2	20	20,536,628 - 20,609,746 (-)	NCBI
Rnor_6.0	20	21,933,414 - 22,004,274 (-)	NCBI
Rnor_5.0	20	24,018,286 - 24,102,848 (-)	NCBI

Sequence:

show sequence

AAGGCCGGCTGTAGCAGAGGGTCTGTGCAGAGTCCTCGGGTCTCGTGCTGTTCTAGAGACGGAG
CGGACCCTAGTGCGCTTGCGCGGCGTCGTGGGCCGGGTTCCCCTGCAGCTCGGACTTGGTACGG
CCGAGCGGTTGGTGCGGTCTGCAGCTGCAGCCCCGGGGCGCGCTTTTCAAATCGTGGTTGACGT
GCGCCGAAATGGAAGGGCAGCTGCTGAGGGGCCTCGCCGCGCAGCAGGACTGCAGCATCCAAGA
GAAAATAGACTTAGAGATCCGAATGCGAGAAGGAATATGGAAACTGCTCTCCCTGAGTAAAAAA
AAAGACCAGGTTTTGCACGCAGTTAAGAACCTCATGGTCTGCAATGCTCGGATGCAGGTGTACA
CGGCGGAGCTGCAGAAGTTAGAAGAGACTGCAAGTCAAACCGGAAGACGGGATGCGAGTTTAGA
AACTAAAGAACAAGAACCCTGCAGAGGGAAGATCGCTCTGTCAGATATTCGAATACCGTTAATG
TGGAAAGACTCCGATCACTTCGGTCATAAGGAATGCACACAGCGCTTTGCCATCTTTTGCTTAT
TCAGGATGGGAACCCAAGTGTTTGACACCGACATGATGATTGTGGACCAGACCGTCACAGATAT
ATGTTTTGAAAACGTCACCATATTCAACGAAGCAGGACCAGACTTCCGGGTAAAGATAGAGGTC
TACAGCAGCAGCGCAGAGGAATCTTCCATAACCAACACCCCCAAAAAGCTGGCTAAAAAGCTGA
AGACGTCCATCAGCAAAGCTACGGGAAGGAAGATAAGTGCTGTGCTGCAGGAGGAGGACCAGGA
GGCGAGCCTGCTTGTCAGCTCCGTGGCGGGAGCAAAGTACCATTTACTAGCTCACACCACCCTG
ACCTTGGAAAATGCCGGAGACTGCTTCAAGACCCATAACCTGTCGGTTCACGGAGATGAGGAGT
GTTCCTTTTGGCTTCCCTTGTATGGCAACCTATGCTGTCGGCTAGTGGCCCAGCCAGCCTGCAT
GGCTGAAGACGCATTTGCAGGATTCCTTAATGAGCAGCAAACAGGAAAAGGTTTGGTTGGCTGG
AGAAGGTTGTACTGTGCTCTGAGAGGGGGTAAACTCCGCTGTTTTTATGGTCCAGAAGAAATTG
AAGCCAAAGTGGAACCGACTCTGGTGATTCCTGTTGACAAGGAAACCAGGATCCAGGCCATGGA
AAAGGATTCAAAGAAAATGCACTGCTTCTCCGTCCTCACCACGGCTGCTGGGCGAGCAGTGAGT
CACATCTTTGCGGCTGACGGCCTAGGAGACTTTCAAGAATGGATGGACGCTTTCCGGCAGCACC
GCTTTGATCTCAGCCACTGGAAGCATTGTTGTGAAGAACTTATGAGAATTGAGATTATGTCACC
ACGGAAACCACCTTTGTTCCTGGCAAAGGAGGCGACTTCAGTGTATCACGATATGAGCATTGAT
TCACCTGTGAAACTCGAAAGCGTGACGGACATAATACAAAAAAAAATCGGAGAGACCAATGGAC
AGTTCCTCATTGGTCGGGAGGAGGAATCCACAACACCCCCGTGGGCCTCAGTGTTTGATGGCAG
CCATGAGATGGTCATCCAGAAGAAAGTCTTGTCCCCAGCAGGCAAACCAGCACCGGATGGGAAA
AGGAAAAAGAGACGTGCTCCCCTCCCTCCTATGGATCAGCCTCCCTTCAGTGTAAAGACACAAG
GTAGCATGGGTCAGTCCAAGGACAGCGAAGCCCAGGTCGGTGTCTCTGGGGCCCCATCTTCAGA
TCGCAGACTGTCACCGCCTACGCATCACCTCCAGAAACCGGTGGCTGCCCCTCGCAAACTTCTC
CCCACCAGGAAAAGCAGTTCAGAGGACAGCGGGCCCACAGATGCTAAAACCAGTTTGGACGGGA
AGCCAGTGCCAGCTCCAAGGCAGAAATCCATCAGAGACATTCTGGACCCTCGATCGTGGCTCCA
AGCACAAGTGTAGGAAGCCTGTACTGTGTAAATCCAGCTGTAAGGCTCGGTCAGAGGCATTGTG
AGTGTAATGTTAGATAATTGTAGAGGTAAAGACCAGAGCAGTTTCCGGAAGCCATTAATAAGTG
GTTAGATACAGAAAAGCACCTTTAAATAGAGAATTGGATTTCCCCTTTACTTCTCCTTTCCAGA
ATATCAATGGTTTCTCCCCACGGAACAAAAGAGGAAATTTCTAGACAATATCTTACTCGTTGGA
AGGGTTAATTTATTCCTAATTTTGTAGCAGGCAGTGGACAGGCAGCAGGCATTAAAAGCATTGA
TTTTTTTTTGGGGGGGGGGTAAAATGTCTTCAATACAAGCCACATTCTCATTGTGAGAACTTTA
ATACTTAACGGAGTGCTTCAAAGGTTTTACTCAAACCACAAATTACAGAATCCACCCAAGGAAA
TGTGTCCGGTCAGCTTTCTGGGATTCTCATCTAACAGTCCTCTGGATCCCTCCCCTCTGTTGTT
TAACTCAATGATCTATAGGGTTGACCTTTTTAAATTCCTGGGATACATTTTCGAATATTAAACC
CTTTATCTTTAAAGGGAATTTGTAATCTGCTATTCAAAGTCATTTCTTTGATGAGCCCTGAAAT
CCTGTTGACTTCACCGCTTGCAGTGAGGCCCACCCTTCTTAGGGAGTGAAGTGGATGTGAAATG
TCCCCCTTCGTCCTGCTTGCCATAGGATGCTAATCTCCGTTTGTGGCCTCTGGAATTCAGGGAG
ACAAGTCGCTGACTAATGCCTTAAATTTTTACTTAATACTTTAAAAGCAGATGGCAGATTCAAA
AAATTATCAGGAAGGTTGACCGCAGTAATCTTCAGAATTAATCCTTTTTCAATTTTTTAATTAG
ATTTTCCTTTTTTTTTTTTTTTTTGAGTAAGGACTGATGTCTGTTATTGATATTGTCTGATATT
GTGTTACTGATATTCATTCAGTAATCACATTGGCGTCATTTCCATAGGAGGTAATTTCCATAGC
AACTAATCACAGTGACCCAAACAGGATTATAAATTGAATGGGGGGATAAATAGCAAGAGGATGA
ATATCTTAAACGGACAAAAAGAAAAATCCACTTTTTATAATAACCCCTTTTGTAAACAAGAGTA
GCGGAACAGTTTTAAAATGTCATCAGAATTTCCAAGCAAACTTCCCAGAGGGTATTTGCACCAG
TTCTGAAAAGTCCAGGACCTCCCACGCCCTAACGGGTACCATAATCCATCACGCTGAAGGAATG
AGTTCTGTCAATCTGGATGGGAACTACGCCCACGTAAAATGGCCAACCGAGGTATTGATGGGAC
CAACCATTCACCGTTTTTAGATAGCAGAGGGGAATAGTTCGTCTGTCTGTTGCTTGCCCAGGAA
CCCCCAGTAAAAAGGGGAACCCGGGTCCAGTGACACACAGCCCTTGTGAAGGTCGAGACTCCTA
CGCCCATGGAAACCCGAAGAATAGATGGGTGTGGTTTTGTTTTTGTTTTAATCTAACTGAAAGG
GTCTGGGAAGTTTTGGTGGTAATTACCATTTCTTTGCTTTCTTTTTATACTTATTTTATGTATA
TGAGTACACTGTGGCTGTCTTCAGACACACCAGAAGA

hide sequence

RefSeq Acc Id:

XM_039098751 ⟹ XP_038954679

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	20,535,553 - 20,598,747 (-)	NCBI
mRatBN7.2	20	20,536,628 - 20,600,194 (-)	NCBI

RefSeq Acc Id:

XM_039098753 ⟹ XP_038954681

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	20,535,553 - 20,566,245 (-)	NCBI
mRatBN7.2	20	20,536,628 - 20,567,344 (-)	NCBI

RefSeq Acc Id:

XM_039098754 ⟹ XP_038954682

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	20,535,553 - 20,567,326 (-)	NCBI
mRatBN7.2	20	20,536,628 - 20,569,655 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101095	(Get FASTA)	NCBI Sequence Viewer
	XP_006256429	(Get FASTA)	NCBI Sequence Viewer
	XP_038954679	(Get FASTA)	NCBI Sequence Viewer
	XP_038954681	(Get FASTA)	NCBI Sequence Viewer
	XP_038954682	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL97315	(Get FASTA)	NCBI Sequence Viewer
	EDL97316	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000060630.1
	ENSRNOP00000072047
	ENSRNOP00000072047.2
	ENSRNOP00000079187.1
	ENSRNOP00000081437.1
	ENSRNOP00000083152.1
	ENSRNOP00000096702
	ENSRNOP00000096702.1

RefSeq Acc Id:

NP_001101095 ⟸ NM_001107625

- UniProtKB:

A0A8I6APU0 (UniProtKB/TrEMBL), A0A8I5ZWM2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAEDAFAGFLNEQQTGKGLVGWRRLYCALRGGKLRCFYGPEEIEAKVEPTLVIPVDKETRIQAM
EKDSKKMHCFSVLTTAAGRAVSHIFAADGLGDFQEWMDAFRQHRFDLSIDSPVKLESVTDIIQK
KIGETNGQFLIGREEESTTPPWASVFDGSHEMVIQKKVLSPAGKPAPDGKRKKRRAPLPPMDQP
PFSVKTQGSMGQSKDSEAQVGVSGAPSSDRRLSPPTHHLQKPVAAPRKLLPTRKSSSEDSGPTD
AKTSLDGKPVPAPRQKSIRDILDPRSWLQAQV

hide sequence

RefSeq Acc Id:	XP_006256429 ⟸ XM_006256367
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZWM2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEGQLLRGLAAQQDCSIQEKIDLEIRMREGIWKLLSLSKKKDQVLHAVKNLMVCNARMQVYTAE LQKLEETASQTGRRDASLETKEQEPCRGKIALSDIRIPLMWKDSDHFGHKECTQRFAIFCLFRM GTQVFDTDMMIVDQTVTDICFENVTIFNEAGPDFRVKIEVYSSSAEESSITNTPKKLAKKLKTS ISKATGRKISAVLQEEDQEASLLVSSVAGAKYHLLAHTTLTLENAGDCFKTHNLSVHGDEECSF WLPLYGNLCCRLVAQPACMAEDAFAGFLNEQQTGKGLVGWRRLYCALRGGKLRCFYGPEEIEAK VEPTLVIPVDKETRIQAMEKDSKKMHCFSVLTTAAGRAVSHIFAADGLGDFQEWMDAFRQHRFD LSHWKHCCEELMRIEIMSPRKPPLFLAKEATSVYHDMSIDSPVKLESVTDIIQKKIGETNGQFL IGREEESTTPPWASVFDGSHEMVIQKKVLSPAGKPAPDGKRKKRRAPLPPMDQPPFSVKTQGSM GQSKDSEAQVGVSGAPSSDRRLSPPTHHLQKPVAAPRKLLPTRKSSSEDSGPTDAKTSLDGKPV PAPRQKSIRDILDPRSWLQAQV hide sequence

Ensembl Acc Id:

ENSRNOP00000060630 ⟸ ENSRNOT00000068778

Ensembl Acc Id:

ENSRNOP00000072047 ⟸ ENSRNOT00000086250

RefSeq Acc Id:	XP_038954679 ⟸ XM_039098751
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5ZWM2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038954682 ⟸ XM_039098754
- Peptide Label:	isoform X4
- UniProtKB:	A0A0G2K1Z6 (UniProtKB/TrEMBL), A6JKV0 (UniProtKB/TrEMBL), D3ZK83 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038954681 ⟸ XM_039098753
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000079187 ⟸ ENSRNOT00000120105

Ensembl Acc Id:

ENSRNOP00000083152 ⟸ ENSRNOT00000110488

Ensembl Acc Id:

ENSRNOP00000096702 ⟸ ENSRNOT00000118813

Ensembl Acc Id:

ENSRNOP00000081437 ⟸ ENSRNOT00000093984

Protein Domains

PH REM-1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K1Z6-F1-model_v2	AlphaFold	A0A0G2K1Z6	1-598	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701565

Promoter ID:

EPDNEW_R12083

Type:

single initiation site

Name:

Rtkn2_1

Description:

rhotekin 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	22,004,248 - 22,004,308	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304834	AgrOrtholog
BioCyc Gene	G2FUF-3900	BioCyc
Ensembl Genes	ENSRNOG00000000636	Ensembl, UniProtKB/TrEMBL
	ENSRNOG00000067849	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000068778.3	UniProtKB/TrEMBL
	ENSRNOT00000086250	ENTREZGENE
	ENSRNOT00000086250.2	UniProtKB/TrEMBL
	ENSRNOT00000093984.1	UniProtKB/TrEMBL
	ENSRNOT00000110488.1	UniProtKB/TrEMBL
	ENSRNOT00000118813	ENTREZGENE
	ENSRNOT00000118813.1	UniProtKB/TrEMBL
	ENSRNOT00000120105.1	UniProtKB/TrEMBL
Gene3D-CATH	2.30.29.30	UniProtKB/TrEMBL
InterPro	AHD	UniProtKB/TrEMBL
	Cytokinesis/Rho-signaling	UniProtKB/TrEMBL
	HR1_rho-bd	UniProtKB/TrEMBL
	PH_type	UniProtKB/TrEMBL
	Pleckstrin_homology	UniProtKB/TrEMBL
KEGG Report	rno:309729	UniProtKB/TrEMBL
NCBI Gene	309729	ENTREZGENE
PANTHER	ANILLIN/RHOTEKIN RTKN	UniProtKB/TrEMBL
	PTHR21538:SF21	UniProtKB/TrEMBL
Pfam	Anillin	UniProtKB/TrEMBL
	PF00169	UniProtKB/TrEMBL
PhenoGen	Rtkn2	PhenoGen
PROSITE	PH_DOMAIN	UniProtKB/TrEMBL
	REM_1	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000000636	RatGTEx
	ENSRNOG00000067849	RatGTEx
SMART	Hr1	UniProtKB/TrEMBL
	SM00233	UniProtKB/TrEMBL
Superfamily-SCOP	PH domain-like	UniProtKB/TrEMBL
UniProt	A0A0G2K1Z6	ENTREZGENE
	A0A8I5ZSI8_RAT	UniProtKB/TrEMBL
	A0A8I5ZWM2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6APU0	ENTREZGENE, UniProtKB/TrEMBL
	A6JKV0	ENTREZGENE, UniProtKB/TrEMBL
	D3ZK83	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A0G2K1Z6	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2010-04-23	Rtkn2	rhotekin 2	Plekhk1	pleckstrin homology domain containing, family K member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Plekhk1	pleckstrin homology domain containing, family K member 1	Plekhk1_predicted	pleckstrin homology domain containing, family K member 1 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Plekhk1_predicted	pleckstrin homology domain containing, family K member 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar