Ly6g6f (lymphocyte antigen 6 family member G6F) - Rat Genome Database

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Gene: Ly6g6f (lymphocyte antigen 6 family member G6F) Rattus norvegicus
Analyze
Symbol: Ly6g6f (Ensembl: Ly6g6d)
Name: lymphocyte antigen 6 family member G6F (Ensembl:lymphocyte antigen 6 family member G6D)
RGD ID: 1303333
Description: Predicted to be located in plasma membrane. Orthologous to human LY6G6F (lymphocyte antigen 6 family member G6F); INTERACTS WITH amphetamine; bis(2-ethylhexyl) phthalate; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: G6f; G6f gene; lymphocyte antigen 6 complex locus protein G6f; lymphocyte antigen 6 complex, locus G6F
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,742,116 - 3,746,984 (+)NCBIGRCr8
mRatBN7.2203,737,459 - 3,742,327 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,737,459 - 3,752,248 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,436,626 - 4,441,648 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0203,798,679 - 3,803,701 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,336,523 - 4,341,546 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,071,041 - 5,076,627 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,071,062 - 5,076,586 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,143,971 - 7,149,557 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,801,118 - 3,805,986 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1203,801,344 - 3,806,213 (+)NCBI
Celera204,283,655 - 4,288,523 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The genomic sequence and comparative analysis of the rat major histocompatibility complex. Hurt P, etal., Genome Res 2004 Apr;14(4):631-9.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Ly6g6f
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,742,116 - 3,746,984 (+)NCBIGRCr8
mRatBN7.2203,737,459 - 3,742,327 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,737,459 - 3,752,248 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,436,626 - 4,441,648 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0203,798,679 - 3,803,701 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,336,523 - 4,341,546 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,071,041 - 5,076,627 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,071,062 - 5,076,586 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,143,971 - 7,149,557 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,801,118 - 3,805,986 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1203,801,344 - 3,806,213 (+)NCBI
Celera204,283,655 - 4,288,523 (-)NCBICelera
Cytogenetic Map20p12NCBI
LY6G6F
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,706,866 - 31,710,679 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl631,706,866 - 31,710,679 (+)EnsemblGRCh38hg38GRCh38
GRCh37631,674,643 - 31,678,456 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,782,663 - 31,786,351 (+)NCBINCBI36Build 36hg18NCBI36
Build 34631,782,662 - 31,786,351NCBI
Celera633,272,902 - 33,276,590 (+)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef631,460,902 - 31,464,590 (+)NCBIHuRef
CHM1_1631,676,801 - 31,680,489 (+)NCBICHM1_1
T2T-CHM13v2.0631,559,901 - 31,563,714 (+)NCBIT2T-CHM13v2.0
Ly6g6f
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,299,514 - 35,304,571 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1735,299,456 - 35,304,586 (-)EnsemblGRCm39 Ensembl
GRCm381735,080,538 - 35,085,595 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,080,480 - 35,085,610 (-)EnsemblGRCm38mm10GRCm38
MGSCv371735,217,483 - 35,222,540 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,688,536 - 34,693,666 (-)NCBIMGSCv36mm8
Celera1738,177,222 - 38,182,277 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.59NCBI
Ly6g6f
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437247,094 - 250,695 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955437247,408 - 250,877 (+)NCBIChiLan1.0ChiLan1.0
LOC100969283
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,183,226 - 46,195,191 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,144,718 - 42,156,680 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,367,840 - 31,372,220 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,257,047 - 32,267,942 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,257,047 - 32,267,909 (+)Ensemblpanpan1.1panPan2
LY6G6F
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,185,592 - 1,189,757 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,322,247 - 1,325,462 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,331,051 - 1,334,270 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,331,077 - 1,336,071 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,190,377 - 1,201,671 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,257,548 - 1,260,761 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,324,994 - 1,328,210 (+)NCBIUU_Cfam_GSD_1.0
LOC101960526
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494635,735,761 - 35,745,170 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,822,803 - 1,825,563 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_0049367271,816,220 - 1,817,933 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367271,822,803 - 1,825,563 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LY6G6F
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,817,640 - 23,822,382 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,815,682 - 23,823,306 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103221756
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11740,313,045 - 40,340,331 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1740,305,738 - 40,316,963 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604431,618,212 - 31,630,506 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ly6g6f
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,500,678 - 24,503,519 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475424,499,550 - 24,504,048 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ly6g6f
76 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:145
Count of miRNA genes:111
Interacting mature miRNAs:116
Transcripts:ENSRNOT00000037613
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
61448Ciaa1CIA Autoantibody QTL 1300.001blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)2026463954597031Rat
61472Aia1Adjuvant induced arthritis QTL 1180.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2026463954597031Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036216499243559Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362164910078919Rat
737973Pia21Pristane induced arthritis QTL 214.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2036216564606812Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 4 4 2 4
Low 20 20 20 9 20 4 4 8
Below cutoff 1 20 15 11 2 11 1 1 31 18 17 3 1

Sequence


RefSeq Acc Id: ENSRNOT00000001120   ⟹   ENSRNOP00000001120
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,749,582 - 3,752,248 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000037613   ⟹   ENSRNOP00000035547
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,737,489 - 3,752,222 (+)Ensembl
Rnor_6.0 Ensembl205,071,062 - 5,076,586 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076253   ⟹   ENSRNOP00000068053
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,737,459 - 3,752,222 (+)Ensembl
Rnor_6.0 Ensembl205,071,323 - 5,076,539 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097767   ⟹   ENSRNOP00000084821
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,741,973 - 3,752,222 (+)Ensembl
RefSeq Acc Id: NM_001003691   ⟹   NP_001003691
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8203,742,116 - 3,746,984 (+)NCBI
mRatBN7.2203,737,459 - 3,742,327 (+)NCBI
Rnor_6.0205,071,704 - 5,076,572 (-)NCBI
Rnor_5.0207,143,971 - 7,149,557 (-)NCBI
RGSC_v3.4203,801,118 - 3,805,986 (+)RGD
Celera204,283,655 - 4,288,523 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001003691 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAE83990 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000035547.6
  ENSRNOP00000068053
  ENSRNOP00000068053.1
  ENSRNOP00000084821.1
GenBank Protein Q6MG56 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001003691   ⟸   NM_001003691
- Peptide Label: precursor
- UniProtKB: Q6MG56 (UniProtKB/Swiss-Prot),   A0A096MJA3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000035547   ⟸   ENSRNOT00000037613
RefSeq Acc Id: ENSRNOP00000068053   ⟸   ENSRNOT00000076253
RefSeq Acc Id: ENSRNOP00000001120   ⟸   ENSRNOT00000001120
RefSeq Acc Id: ENSRNOP00000084821   ⟸   ENSRNOT00000097767
Protein Domains
Ig-like   Ig-like V-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6MG56-F1-model_v2 AlphaFold Q6MG56 1-293 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303333 AgrOrtholog
BioCyc Gene G2FUF-4641 BioCyc
Ensembl Genes ENSRNOG00000027225 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000037613.6 UniProtKB/TrEMBL
  ENSRNOT00000076253 ENTREZGENE
  ENSRNOT00000076253.2 UniProtKB/TrEMBL
  ENSRNOT00000097767.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.60.10 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LY6G6d/LY6G6f UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Snake_toxin-like_sf UniProtKB/TrEMBL
NCBI Gene 309609 ENTREZGENE
PANTHER LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G6D UniProtKB/TrEMBL
  LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G6F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR32286 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ly6g6f PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000027225 RatGTEx
SMART SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57302 UniProtKB/TrEMBL
UniProt A0A096MJA3 ENTREZGENE, UniProtKB/TrEMBL
  A0A140TAE8_RAT UniProtKB/TrEMBL
  A0A1L6ZA26_RAT UniProtKB/TrEMBL
  LY66F_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A0A1L6ZA30 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-02-01 Ly6g6f  lymphocyte antigen 6 family member G6F  Ly6g6f  lymphocyte antigen 6 complex, locus G6F  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Ly6g6f  lymphocyte antigen 6 complex, locus G6F  G6f  G6f gene  Symbol and Name updated 1299863 APPROVED
2005-10-07 G6f        Symbol and Name status set to provisional 70820 PROVISIONAL