Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Bhlhb9 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of BHLHB9 mRNA | CTD | PMID:36331819 | 1,2-dichloroethane | decreases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of BHLHB9 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of GPRASP3 mRNA | CTD | PMID:27840820 | 17beta-estradiol | decreases expression | ISO | GPRASP3 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of GPRASP3 mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of BHLHB9 mRNA | CTD | PMID:21570461 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of GPRASP3 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of GPRASP3 mRNA | CTD | PMID:21346803 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of GPRASP3 mRNA | CTD | PMID:24780913 | acrylamide | increases expression | ISO | GPRASP3 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of GPRASP3 mRNA | CTD | PMID:32763439 | all-trans-retinoic acid | decreases expression | ISO | GPRASP3 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of GPRASP3 mRNA | CTD | PMID:21934132 | antirheumatic drug | increases expression | ISO | GPRASP3 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of GPRASP3 mRNA | CTD | PMID:24449571 | azoxystrobin | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GPRASP3 mRNA | CTD | PMID:33854195 | benzo[a]pyrene | decreases expression | ISO | GPRASP3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of GPRASP3 mRNA | CTD | PMID:20106945 | benzo[a]pyrene | affects methylation | ISO | GPRASP3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of GPRASP3 5' UTR and Benzo(a)pyrene affects the methylation of GPRASP3 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of BHLHB9 mRNA | CTD | PMID:19770486 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of GPRASP3 mRNA | CTD | PMID:30816183 more ... | bisphenol A | decreases methylation | ISO | GPRASP3 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of GPRASP3 gene | CTD | PMID:31601247 | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of GPRASP3 mRNA | CTD | PMID:19167457 | cadmium atom | decreases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | Cadmium results in decreased expression of BHLHB9 mRNA | CTD | PMID:24067728 | cadmium atom | multiple interactions | ISO | GPRASP3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GPRASP3 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | GPRASP3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GPRASP3 mRNA | CTD | PMID:35301059 | cantharidin | decreases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | Cantharidin results in decreased expression of BHLHB9 mRNA | CTD | PMID:36907384 | CGP 52608 | multiple interactions | ISO | GPRASP3 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to GPRASP3 gene] | CTD | PMID:28238834 | chlorpyrifos | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GPRASP3 mRNA | CTD | PMID:33854195 | choline | multiple interactions | ISO | Bhlhb9 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BHLHB9 mRNA | CTD | PMID:20938992 | clofibrate | increases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | Clofibrate results in increased expression of BHLHB9 mRNA | CTD | PMID:23811191 | crocidolite asbestos | decreases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of BHLHB9 mRNA | CTD | PMID:29279043 | cyclosporin A | decreases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of BHLHB9 mRNA | CTD | PMID:19770486 | cyclosporin A | decreases expression | ISO | GPRASP3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of GPRASP3 mRNA | CTD | PMID:20106945 more ... | dichloroacetic acid | increases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | Dichloroacetic Acid results in increased expression of BHLHB9 mRNA | CTD | PMID:28962523 | dorsomorphin | multiple interactions | ISO | GPRASP3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of GPRASP3 mRNA | CTD | PMID:29391264 | ethanol | affects expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | Ethanol affects the expression of BHLHB9 mRNA | CTD | PMID:30319688 | ethanol | affects splicing | ISO | Bhlhb9 (Mus musculus) | 6480464 | Ethanol affects the splicing of BHLHB9 mRNA | CTD | PMID:30319688 | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of GPRASP3 mRNA | CTD | PMID:24793618 | folic acid | multiple interactions | ISO | Bhlhb9 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BHLHB9 mRNA | CTD | PMID:20938992 | formaldehyde | increases expression | ISO | GPRASP3 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of GPRASP3 mRNA | CTD | PMID:23649840 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of GPRASP3 mRNA | CTD | PMID:33387578 | glyphosate | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GPRASP3 mRNA | CTD | PMID:33854195 | imidacloprid | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GPRASP3 mRNA | CTD | PMID:33854195 | inulin | multiple interactions | ISO | Bhlhb9 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of BHLHB9 mRNA | CTD | PMID:36331819 | L-methionine | multiple interactions | ISO | Bhlhb9 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BHLHB9 mRNA | CTD | PMID:20938992 | methyl methanesulfonate | increases expression | ISO | GPRASP3 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of GPRASP3 mRNA | CTD | PMID:23649840 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of GPRASP3 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Bhlhb9 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of BHLHB9 mRNA more ... | CTD | PMID:36331819 | perfluorooctanoic acid | increases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | perfluorooctanoic acid results in increased expression of BHLHB9 mRNA | CTD | PMID:30711707 | permethrin | increases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | Permethrin results in increased expression of BHLHB9 mRNA | CTD | PMID:30629241 | phenobarbital | affects expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | Phenobarbital affects the expression of BHLHB9 mRNA | CTD | PMID:19136022 and PMID:23091169 | phenylmercury acetate | decreases expression | ISO | GPRASP3 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of GPRASP3 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | GPRASP3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPRASP3 mRNA | CTD | PMID:27188386 | pirinixic acid | affects expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | pirinixic acid affects the expression of BHLHB9 mRNA | CTD | PMID:19136022 | pirinixic acid | increases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of BHLHB9 mRNA | CTD | PMID:18301758 and PMID:23811191 | pirinixic acid | multiple interactions | ISO | Bhlhb9 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of BHLHB9 mRNA | CTD | PMID:19710929 | SB 431542 | multiple interactions | ISO | GPRASP3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | increases expression | ISO | GPRASP3 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of GPRASP3 mRNA | CTD | PMID:25879800 | sunitinib | decreases expression | ISO | GPRASP3 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of GPRASP3 mRNA | CTD | PMID:31533062 | testosterone | increases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | Testosterone deficiency results in increased expression of BHLHB9 mRNA | CTD | PMID:33848595 | tetrachloromethane | increases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of BHLHB9 mRNA | CTD | PMID:17484886 and PMID:27339419 | tetrachloromethane | decreases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of BHLHB9 mRNA | CTD | PMID:31919559 | thiabendazole | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GPRASP3 mRNA | CTD | PMID:33854195 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of GPRASP3 mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of BHLHB9 mRNA | CTD | PMID:29264374 | trichostatin A | decreases expression | ISO | GPRASP3 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of GPRASP3 mRNA | CTD | PMID:24935251 | Triptolide | decreases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | triptolide results in decreased expression of BHLHB9 mRNA | CTD | PMID:32835833 | tris(2-butoxyethyl) phosphate | affects expression | ISO | GPRASP3 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of GPRASP3 mRNA | CTD | PMID:29024780 | troglitazone | increases expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | Troglitazone results in increased expression of BHLHB9 mRNA | CTD | PMID:28973697 | valproic acid | decreases methylation | ISO | GPRASP3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of GPRASP3 gene | CTD | PMID:29154799 | valproic acid | multiple interactions | ISO | GPRASP3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPRASP3 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | GPRASP3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of GPRASP3 mRNA | CTD | PMID:29154799 | valproic acid | affects expression | ISO | Bhlhb9 (Mus musculus) | 6480464 | Valproic Acid affects the expression of BHLHB9 mRNA | CTD | PMID:17292431 | valproic acid | decreases expression | ISO | GPRASP3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of GPRASP3 mRNA | CTD | PMID:23179753 more ... | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of GPRASP3 mRNA | CTD | PMID:23034163 | |