Or12d17 (olfactory receptor family 12 subfamily D member 17) - Rat Genome Database

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Gene: Or12d17 (olfactory receptor family 12 subfamily D member 17) Rattus norvegicus
Analyze
Symbol: Or12d17
Name: olfactory receptor family 12 subfamily D member 17
RGD ID: 1303153
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR12D3 (olfactory receptor family 12 subfamily D member 3); INTERACTS WITH bisphenol A; benzo[a]pyrene (ortholog); CGP 52608 (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MOR250-1; olfactory receptor 1868; olfactory receptor 29; Olr1868; Or29
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr820998,023 - 998,988 (-)NCBIGRCr8
mRatBN7.220992,771 - 993,736 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl20990,631 - 1,000,725 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx201,024,632 - 1,025,597 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0201,028,088 - 1,029,053 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.020986,659 - 987,624 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0201,322,453 - 1,323,418 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl201,322,453 - 1,323,419 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0201,316,209 - 1,317,174 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera201,731,546 - 1,732,511 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The genomic sequence and comparative analysis of the rat major histocompatibility complex. Hurt P, etal., Genome Res 2004 Apr;14(4):631-9.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or12d17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr820998,023 - 998,988 (-)NCBIGRCr8
mRatBN7.220992,771 - 993,736 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl20990,631 - 1,000,725 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx201,024,632 - 1,025,597 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0201,028,088 - 1,029,053 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.020986,659 - 987,624 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0201,322,453 - 1,323,418 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl201,322,453 - 1,323,419 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0201,316,209 - 1,317,174 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera201,731,546 - 1,732,511 (-)NCBICelera
Cytogenetic Map20p12NCBI
OR12D3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38629,373,423 - 29,375,291 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl629,373,423 - 29,375,291 (-)EnsemblGRCh38hg38GRCh38
GRCh37629,341,200 - 29,343,068 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36629,449,179 - 29,451,047 (-)NCBINCBI36Build 36hg18NCBI36
Build 34629,449,178 - 29,451,047NCBI
Celera630,947,396 - 30,949,264 (-)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef629,148,495 - 29,150,363 (-)NCBIHuRef
CHM1_1629,343,148 - 29,345,016 (-)NCBICHM1_1
T2T-CHM13v2.0629,248,211 - 29,250,079 (-)NCBIT2T-CHM13v2.0
Or12d17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,777,099 - 37,778,043 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1737,769,807 - 37,782,481 (+)EnsemblGRCm39 Ensembl
GRCm381737,466,208 - 37,467,152 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1737,458,916 - 37,471,590 (+)EnsemblGRCm38mm10GRCm38
MGSCv371737,603,153 - 37,604,097 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361737,074,261 - 37,075,205 (+)NCBIMGSCv36mm8
Celera1740,896,990 - 40,897,934 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1719.16NCBI
LOC102013125
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555761,441,105 - 1,442,064 (-)NCBIChiLan1.0ChiLan1.0
LOC100971996
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2544,005,379 - 44,007,203 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1639,969,745 - 39,971,569 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0629,191,112 - 29,192,936 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1629,849,219 - 29,851,044 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl629,850,090 - 29,851,040 (-)Ensemblpanpan1.1panPan2
LOC100156546
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.2725,760,807 - 25,761,757 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Or12d17
8 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:85
Count of miRNA genes:74
Interacting mature miRNAs:75
Transcripts:ENSRNOT00000075472
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

hemolymphoid system nervous system renal system reproductive system
High
Medium
Low 1
Below cutoff 2 1 7 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000075472   ⟹   ENSRNOP00000065579
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,322,453 - 1,323,419 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000099517   ⟹   ENSRNOP00000095335
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl20990,659 - 1,000,725 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000101063   ⟹   ENSRNOP00000076376
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl20990,631 - 1,000,725 (-)Ensembl
RefSeq Acc Id: NM_213731   ⟹   NP_998896
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr820998,023 - 998,988 (-)NCBI
mRatBN7.220992,771 - 993,736 (-)NCBI
Rnor_6.0201,322,453 - 1,323,418 (+)NCBI
Rnor_5.0201,316,209 - 1,317,174 (+)NCBI
Celera201,731,546 - 1,732,511 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_998896 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAG25962 (Get FASTA)   NCBI Sequence Viewer  
  EDL84640 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000076376.1
  ENSRNOP00000095335
  ENSRNOP00000095335.1
Reference Protein Sequences
RefSeq Acc Id: NP_998896   ⟸   NM_213731
- UniProtKB: Q6ZMA0 (UniProtKB/TrEMBL),   A6KR49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000065579   ⟸   ENSRNOT00000075472
RefSeq Acc Id: ENSRNOP00000095335   ⟸   ENSRNOT00000099517
RefSeq Acc Id: ENSRNOP00000076376   ⟸   ENSRNOT00000101063
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6ZMA0-F1-model_v2 AlphaFold Q6ZMA0 1-321 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303153 AgrOrtholog
BioCyc Gene G2FUF-5038 BioCyc
Ensembl Genes ENSRNOG00000047298 Ensembl
  ENSRNOG00000065687 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000099517 ENTREZGENE
  ENSRNOT00000099517.1 UniProtKB/TrEMBL
  ENSRNOT00000101063.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:408030 UniProtKB/TrEMBL
NCBI Gene 408030 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or12d17 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047298 RatGTEx
  ENSRNOG00000065687 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6KR49 ENTREZGENE, UniProtKB/TrEMBL
  Q6ZMA0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or12d17  olfactory receptor family 12 subfamily D member 17  Olr1868  olfactory receptor 1868  Symbol and Name Changed 1299863 APPROVED
2008-10-09 Olr1868  olfactory receptor 1868  Or29  olfactory receptor 29  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-02-14 Or29  olfactory receptor 29      Symbol and Name status set to provisional 70820 PROVISIONAL