Ece2 (endothelin-converting enzyme 2) - Rat Genome Database

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Gene: Ece2 (endothelin-converting enzyme 2) Rattus norvegicus
Analyze
Symbol: Ece2
Name: endothelin-converting enzyme 2
RGD ID: 1303039
Description: Predicted to enable metalloendopeptidase activity. Predicted to be involved in peptide hormone processing. Predicted to be located in cytoplasmic vesicle membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including ECE2 (endothelin converting enzyme 2); INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: endothelin converting enzyme 2
RGD Orthologs
Human
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21180,259,130 - 80,299,685 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,263,162 - 80,278,428 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1188,985,861 - 89,000,940 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01181,639,279 - 81,654,358 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01180,700,344 - 80,715,423 (-)NCBIRnor_WKY
Rnor_6.01183,948,896 - 83,985,429 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1183,948,230 - 83,964,055 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01187,020,944 - 87,057,771 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41182,492,975 - 82,507,876 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11182,551,275 - 82,565,465 (-)NCBI
Celera1179,102,870 - 79,117,938 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. A genomic analysis of rat proteases and protease inhibitors. Puente XS and Lopez-Otin C, Genome Res 2004 Apr;14(4):609-22.
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11718899   PMID:24847082  


Genomics

Comparative Map Data
Ece2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21180,259,130 - 80,299,685 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,263,162 - 80,278,428 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1188,985,861 - 89,000,940 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01181,639,279 - 81,654,358 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01180,700,344 - 80,715,423 (-)NCBIRnor_WKY
Rnor_6.01183,948,896 - 83,985,429 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1183,948,230 - 83,964,055 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01187,020,944 - 87,057,771 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41182,492,975 - 82,507,876 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11182,551,275 - 82,565,465 (-)NCBI
Celera1179,102,870 - 79,117,938 (-)NCBICelera
Cytogenetic Map11q23NCBI
ECE2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383184,276,022 - 184,293,031 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3184,276,011 - 184,293,031 (+)EnsemblGRCh38hg38GRCh38
GRCh373183,993,810 - 184,010,819 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363185,450,139 - 185,493,513 (+)NCBINCBI36Build 36hg18NCBI36
Build 343185,450,218 - 185,493,520NCBI
Celera3182,408,209 - 182,451,576 (+)NCBICelera
Cytogenetic Map3q27.1NCBI
HuRef3181,374,414 - 181,417,820 (+)NCBIHuRef
CHM1_13183,931,867 - 183,975,288 (+)NCBICHM1_1
T2T-CHM13v2.03187,085,301 - 187,102,316 (+)NCBIT2T-CHM13v2.0
ECE2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383184,276,022 - 184,293,031 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3184,276,011 - 184,293,031 (+)EnsemblGRCh38hg38GRCh38
GRCh373183,993,810 - 184,010,819 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363185,450,139 - 185,493,513 (+)NCBINCBI36Build 36hg18NCBI36
Build 343185,450,218 - 185,493,520NCBI
Celera3182,408,209 - 182,451,576 (+)NCBICelera
Cytogenetic Map3q27.1NCBI
HuRef3181,374,414 - 181,417,820 (+)NCBIHuRef
CHM1_13183,931,867 - 183,975,288 (+)NCBICHM1_1
T2T-CHM13v2.03187,085,301 - 187,102,316 (+)NCBIT2T-CHM13v2.0
Eef1ece2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391620,430,351 - 20,464,665 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1620,430,360 - 20,464,670 (+)EnsemblGRCm39 Ensembl
GRCm381620,611,601 - 20,645,915 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1620,629,828 - 20,646,485 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1620,611,610 - 20,645,920 (+)EnsemblGRCm38mm10GRCm38
MGSCv371620,611,674 - 20,645,988 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361620,543,453 - 20,559,462 (+)NCBIMGSCv36mm8
MGSCv361620,369,701 - 20,385,808 (+)NCBIMGSCv36mm8
Celera1621,175,677 - 21,210,935 (+)NCBICelera
Cytogenetic Map16A3NCBI
Ece2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542023,202,668 - 23,235,977 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542023,199,627 - 23,217,078 (-)NCBIChiLan1.0ChiLan1.0
ECE2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan13182,151,178 - 182,168,230 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03181,310,554 - 181,327,602 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13189,793,521 - 189,809,648 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3189,766,786 - 189,811,206 (+)Ensemblpanpan1.1panPan2
ECE2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13417,141,411 - 17,174,413 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3417,160,521 - 17,173,580 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3417,141,494 - 17,148,444 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3421,227,781 - 21,261,221 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03417,049,083 - 17,082,716 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3417,048,462 - 17,057,180 (+)EnsemblROS_Cfam_1.0 Ensembl
ROS_Cfam_1.0 Ensembl3417,068,127 - 17,083,742 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13417,086,425 - 17,119,843 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03417,082,281 - 17,115,934 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03417,312,508 - 17,345,102 (+)NCBIUU_Cfam_GSD_1.0
LOC101959833
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602119,493,507 - 119,524,796 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365785,585,443 - 5,616,099 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365785,586,086 - 5,615,940 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ECE2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13122,148,943 - 122,156,244 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1 Ensembl13122,165,152 - 122,179,498 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113122,148,928 - 122,179,522 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213131,588,698 - 131,619,271 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ECE2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1155,131,038 - 5,148,829 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl155,130,385 - 5,148,811 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606313,907,178 - 13,925,007 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ece2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473072,301,267 - 72,336,855 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473072,301,693 - 72,336,937 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ece2
88 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:409
Count of miRNA genes:176
Interacting mature miRNAs:210
Transcripts:ENSRNOT00000042833, ENSRNOT00000044482
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116944607082846715Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)117695713183051965Rat

Markers in Region
RH144378  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21180,263,291 - 80,263,452 (+)MAPPERmRatBN7.2
Rnor_6.01183,949,026 - 83,949,186NCBIRnor6.0
Rnor_5.01187,021,074 - 87,021,234UniSTSRnor5.0
RGSC_v3.41182,493,105 - 82,493,265UniSTSRGSC3.4
Celera1179,103,000 - 79,103,160UniSTS
RH 3.4 Map11658.0UniSTS
Cytogenetic Map11q23UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 30 3
Low 3 43 32 18 17 18 7 8 44 34 35 11 7
Below cutoff 23 21 2 21 1 3 1 3 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000044482   ⟹   ENSRNOP00000042149
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1180,263,165 - 80,278,246 (-)Ensembl
Rnor_6.0 Ensembl1183,948,230 - 83,964,055 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093894   ⟹   ENSRNOP00000079117
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1180,263,162 - 80,278,428 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113390   ⟹   ENSRNOP00000094643
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1180,263,165 - 80,278,246 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000119768   ⟹   ENSRNOP00000091720
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1180,263,165 - 80,278,246 (-)Ensembl
RefSeq Acc Id: NM_001002815   ⟹   NP_001002815
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21180,263,162 - 80,278,243 (-)NCBI
Rnor_6.01183,948,896 - 83,963,975 (-)NCBI
Rnor_5.01187,020,944 - 87,057,771 (-)NCBI
RGSC_v3.41182,492,975 - 82,507,876 (-)RGD
Celera1179,102,870 - 79,117,938 (-)RGD
Sequence:
RefSeq Acc Id: XM_006248573   ⟹   XP_006248635
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21180,263,162 - 80,299,685 (-)NCBI
Rnor_6.01183,948,896 - 83,985,429 (-)NCBI
Rnor_5.01187,020,944 - 87,057,771 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039088563   ⟹   XP_038944491
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21180,263,162 - 80,278,446 (-)NCBI
RefSeq Acc Id: XM_039088564   ⟹   XP_038944492
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21180,259,130 - 80,278,445 (-)NCBI
RefSeq Acc Id: XM_039088565   ⟹   XP_038944493
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21180,263,908 - 80,278,444 (-)NCBI
RefSeq Acc Id: XM_039088566   ⟹   XP_038944494
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21180,265,388 - 80,278,444 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001002815   ⟸   NM_001002815
- UniProtKB: D4A4U1 (UniProtKB/TrEMBL),   Q6IE65 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248635   ⟸   XM_006248573
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSRNOP00000042149   ⟸   ENSRNOT00000044482
RefSeq Acc Id: XP_038944492   ⟸   XM_039088564
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038944491   ⟸   XM_039088563
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038944493   ⟸   XM_039088565
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038944494   ⟸   XM_039088566
- Peptide Label: isoform X4
RefSeq Acc Id: ENSRNOP00000094643   ⟸   ENSRNOT00000113390
RefSeq Acc Id: ENSRNOP00000091720   ⟸   ENSRNOT00000119768
RefSeq Acc Id: ENSRNOP00000079117   ⟸   ENSRNOT00000093894
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A4U1-F1-model_v2 AlphaFold D4A4U1 1-765 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698273
Promoter ID:EPDNEW_R8798
Type:multiple initiation site
Name:Ece2_1
Description:endothelin-converting enzyme 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01183,963,983 - 83,964,043EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303039 AgrOrtholog
BioCyc Gene G2FUF-20744 BioCyc
Ensembl Genes ENSRNOG00000001715 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000042149 ENTREZGENE
  ENSRNOP00000042149.4 UniProtKB/TrEMBL
  ENSRNOP00000079117.1 UniProtKB/TrEMBL
  ENSRNOP00000091720.1 UniProtKB/TrEMBL
  ENSRNOP00000094643.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000044482 ENTREZGENE
  ENSRNOT00000044482.7 UniProtKB/TrEMBL
  ENSRNOT00000093894.1 UniProtKB/TrEMBL
  ENSRNOT00000113390.1 UniProtKB/TrEMBL
  ENSRNOT00000119768.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1380.10 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
InterPro MetalloPept_cat_dom UniProtKB/TrEMBL
  Peptidase_M13 UniProtKB/TrEMBL
  Peptidase_M13_C UniProtKB/TrEMBL
  Peptidase_M13_dom_2 UniProtKB/TrEMBL
  Peptidase_M13_N UniProtKB/TrEMBL
KEGG Report rno:408243 UniProtKB/TrEMBL
NCBI Gene 408243 ENTREZGENE
PANTHER EEF1AKMT4-ECE2 READTHROUGH TRANSCRIPT PROTEIN-RELATED UniProtKB/TrEMBL
  PTHR11733 UniProtKB/TrEMBL
Pfam Peptidase_M13 UniProtKB/TrEMBL
  Peptidase_M13_N UniProtKB/TrEMBL
PhenoGen Ece2 PhenoGen
PRINTS NEPRILYSIN UniProtKB/TrEMBL
PROSITE NEPRILYSIN UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
UniProt A0A8I5ZM37_RAT UniProtKB/TrEMBL
  A0A8I6ATJ1_RAT UniProtKB/TrEMBL
  A0A8I6B1B3_RAT UniProtKB/TrEMBL
  D4A4U1 ENTREZGENE, UniProtKB/TrEMBL
  Q6IE65 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-11-17 Ece2  endothelin-converting enzyme 2      Symbol and Name status set to approved 1299863 APPROVED
2005-02-14 Ece2  endothelin-converting enzyme 2      Symbol and Name status set to provisional 70820 PROVISIONAL