Mmp12<sup>em1Soar</sup> (matrix metallopeptidase 12; TALEN induced mutant 1,Soar) - Rat Genome Database

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Gene: Mmp12em1Soar (matrix metallopeptidase 12; TALEN induced mutant 1,Soar) Rattus norvegicus
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Symbol: Mmp12em1Soar
Name: matrix metallopeptidase 12; TALEN induced mutant 1,Soar
RGD ID: 12910500
Description: The TALEN genome editing system caused a 664-bp deletion in the exon 2 of rat Mmp12
ASSOCIATED WITH decreased fetal weight
Type: allele  of Mmp12  
Previously known as: Mmp12^[em1Soar]; Mmp12em1Soar
Is Marker For: Strains:   SD-Mmp12em1Soar  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. HIF-KDM3A-MMP12 regulatory circuit ensures trophoblast plasticity and placental adaptations to hypoxia. Chakraborty D, etal., Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):E7212-E7221. Epub 2016 Nov 2.

Genomics

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Mmp12em1Soar-var1 chr8 4582695 4583358 TTCCTCTGGAATTTTGGTAATCTGACTAATAATTTATAATGTTTTAAATAACATAGGAAGTTATTTTCTCCTCCTTGTAATAGACTCTCTAGGTAATAATAATAATGCAGCCTGTGATTAAAATACCTGGCTCAGGAACATCAGTATGCTACTGACCATGTTTGCAGGATTCCCAGCAGAAACCTGGCCGCATACAACTGTGTGCAATGCTTGTGTTTTGTCTAGTGGTACTTGTCAAGATTTTTTGACTATCAAGGGGACAGAATTCCAATGACAAAAACAAAAACCAATAGAAACCTCCTAGAAGAAAAACTCCAGGAAATGCAGCAGTTCTTTGGGCTAGAAGTAACTGGGCAACTGGACACCTCAACTCTGAAAATAATGCACACGTCTCGATGTGGAGTGCCTGATGTACAGCATCTTAGAGCAGTGCCCCAGAGGTCAAGATGGATGAAGCGGTATCTCACTTACAGGTAATGTCATTGGAGAACTCTTCTACTTGCCTATGAGTGTAGCCTCTAGAACCCTAGAACATTTAGCTACAACGAAATTCTAAATCCAAGAGTAGCCTCTGCAAATTGTTAATACAAATGTGTTCATTTTCTCCAGACTGGGTTGATGGCTCAGTGGAAAAAGCACTTGTCATACACTATAAGGGCCAGAG - deletion mRatBN7.2
Mmp12em1Soar-var1 chr8 5607502 5608165 TTCCTCTGGAATTTTGGTAATCTGACTAATAATTTATAATGTTTTAAATAACATAGGAAGTTATTTTCTCCTCCTTGTAATAGACTCTCTAGGTAATAATAATAATGCAGCCTGTGATTAAAATACCTGGCTCAGGAACATCAGTATGCTACTGACCATGTTTGCAGGATTCCCAGCAGAAACCTGGCCGCATACAACTGTGTGCAATGCTTGTGTTTTGTCTAGTGGTACTTGTCAAGATTTTTTGACTATCAAGGGGACAGAATTCCAATGACAAAAACAAAAACCAATAGAAACCTCCTAGAAGAAAAACTCCAGGAAATGCAGCAGTTCTTTGGGCTAGAAGTAACTGGGCAACTGGACACCTCAACTCTGAAAATAATGCACACGTCTCGATGTGGAGTGCCTGATGTACAGCATCTTAGAGCAGTGCCCCAGAGGTCAAGATGGATGAAGCGGTATCTCACTTACAGGTAATGTCATTGGAGAACTCTTCTACTTGCCTATGAGTGTAGCCTCTAGAACCCTAGAACATTTAGCTACAACGAAATTCTAAATCCAAGAGTAGCCTCTGCAAATTGTTAATACAAATGTGTTCATTTTCTCCAGACTGGGTTGATGGCTCAGTGGAAAAAGCACTTGTCATACACTATAAGGGCCAGAG - deletion Rnor_6.0

Related Rat Strains
The following Strains have been annotated to Mmp12em1Soar
SD-Mmp12em1Soar    


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-16 Mmp12em1Soar  matrix metallopeptidase 12; TALEN induced mutant 1,Soar  Mmp12em1Soar    changed 629549 APPROVED