Ldlr<sup>em1Sage</sup> (low density lipoprotein receptor; ZFN induced mutant 1, Sage) - Rat Genome Database

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Gene: Ldlrem1Sage (low density lipoprotein receptor; ZFN induced mutant 1, Sage) Rattus norvegicus
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Symbol: Ldlrem1Sage
Name: low density lipoprotein receptor; ZFN induced mutant 1, Sage
RGD ID: 12904909
Description: This allele possesses a 337 bp deletion and 4 bp insertion within Exon 4 of rat Ldlr gene
ASSOCIATED WITH impaired glucose tolerance; increased body weight; increased circulating free fatty acids level; ASSOCIATED WITH Hypercholesterolemia; Hypertriglyceridemia
Type: allele  of Ldlr  
Previously known as: Ldlr tm1sage; Ldlr^[em1Sage]; Ldlrem1Sage; low density lipoprotein receptor; endonuclease induced mutant 1, Sage
Is Marker For: Strains:   SD-Ldlrem1Sage  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data curation from Horizon Discovery Data curation from Horizon Discovery (https://www.horizondiscovery.com/)
2. Atherogenesis and metabolic dysregulation in LDL receptor-knockout rats. Sithu SD, etal., JCI Insight. 2017 May 4;2(9). pii: 86442. doi: 10.1172/jci.insight.86442.

Genomics


Related Rat Strains
The following Strains have been annotated to Ldlrem1Sage
SD-Ldlrem1Sage    


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-08 Ldlrem1Sage  low density lipoprotein receptor; ZFN induced mutant 1, Sage  Ldlrem1Sage  low density lipoprotein receptor; endonuclease induced mutant 1, Sage  Name changed 629549 APPROVED