Ghsr<sup>em1Ottc</sup> (growth hormone secretagogue receptor;CRISPR induced mutant 1, Ottc) - Rat Genome Database

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Gene: Ghsrem1Ottc (growth hormone secretagogue receptor;CRISPR induced mutant 1, Ottc) Rattus norvegicus
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Symbol: Ghsrem1Ottc
Name: growth hormone secretagogue receptor;CRISPR induced mutant 1, Ottc
RGD ID: 12880435
Description: Mutation induced by CRISPR in the Ghsr gene,It is a 843-bp deletion mutation resulting knockout of protein expression.
ASSOCIATED WITH decreased body weight; decreased food intake; increased brown adipose tissue amount
Type: allele  of Ghsr  
Previously known as: Ghsr^[em1Ottc]; Ghsrem1Ottc
Is Marker For: Strains:   W-Ghsrem1Ottc  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Development and initial characterization of a novel ghrelin receptor CRISPR/Cas9 knockout wistar rat model. Zallar LJ, etal., Int J Obes (Lond). 2018 Jan 30. pii: 10.1038/s41366-018-0013-5. doi: 10.1038/s41366-018-0013-5.
2. Ghrelin receptor deletion reduces binge-like alcohol drinking in rats. Zallar LJ, etal., J Neuroendocrinol. 2018 Nov 20:e12663. doi: 10.1111/jne.12663.

Genomics


Related Rat Strains
The following Strains have been annotated to Ghsrem1Ottc
W-Ghsrem1Ottc    


Expression


Sequence

Nucleotide Sequences


Additional Information