LINC02368 (long intergenic non-protein coding RNA 2368) - Rat Genome Database

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Gene: LINC02368 (long intergenic non-protein coding RNA 2368) Homo sapiens
Analyze
Symbol: LINC02368
Name: long intergenic non-protein coding RNA 2368
RGD ID: 12801002
HGNC Page HGNC:53291
Description:
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812128,118,217 - 128,121,952 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12128,116,730 - 128,123,103 (+)EnsemblGRCh38hg38GRCh38
GRCh3712128,602,762 - 128,606,497 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map12q24.32NCBI
HuRef12125,589,260 - 125,592,995 (+)NCBIHuRef
CHM1_112128,423,904 - 128,427,639 (+)NCBICHM1_1
T2T-CHM13v2.012128,148,552 - 128,152,287 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 12q24.23-24.33(chr12:118165459-133182322)x3 copy number gain See cases [RCV000050866] Chr12:118165459..133182322 [GRCh38]
Chr12:118603264..133758908 [GRCh37]
Chr12:117087647..132268981 [NCBI36]
Chr12:12q24.23-24.33		 pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:123444758-133191400)x3 copy number gain See cases [RCV000051151] Chr12:123444758..133191400 [GRCh38]
Chr12:123929305..133767986 [GRCh37]
Chr12:122495258..132278059 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.23-24.33(chr12:119417382-133191400)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053691]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053691]|See cases [RCV000053691] Chr12:119417382..133191400 [GRCh38]
Chr12:119855187..133767986 [GRCh37]
Chr12:118339570..132278059 [NCBI36]
Chr12:12q24.23-24.33		 pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:123365769-133191400)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053693]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053693]|See cases [RCV000053693] Chr12:123365769..133191400 [GRCh38]
Chr12:123850316..133767986 [GRCh37]
Chr12:122416269..132278059 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:123509825-133191400)x3 copy number gain See cases [RCV000135535] Chr12:123509825..133191400 [GRCh38]
Chr12:123994372..133767986 [GRCh37]
Chr12:122560325..132278059 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.32(chr12:127802658-128663624)x3 copy number gain See cases [RCV000136702] Chr12:127802658..128663624 [GRCh38]
Chr12:128287203..129148169 [GRCh37]
Chr12:126853156..127714122 [NCBI36]
Chr12:12q24.32		 uncertain significance
GRCh38/hg38 12q24.32-24.33(chr12:127900499-129778294)x3 copy number gain See cases [RCV000137094] Chr12:127900499..129778294 [GRCh38]
Chr12:128385044..130262839 [GRCh37]
Chr12:126950997..128828792 [NCBI36]
Chr12:12q24.32-24.33		 uncertain significance
GRCh38/hg38 12q24.31-24.33(chr12:120697672-133202490)x3 copy number gain See cases [RCV000137651] Chr12:120697672..133202490 [GRCh38]
Chr12:121135475..133779076 [GRCh37]
Chr12:119619858..132289149 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.32(chr12:127145342-128422497)x4 copy number gain See cases [RCV000138658] Chr12:127145342..128422497 [GRCh38]
Chr12:127629887..128907042 [GRCh37]
Chr12:126195840..127472995 [NCBI36]
Chr12:12q24.32		 uncertain significance
GRCh38/hg38 12q24.21-24.33(chr12:114268403-133201316)x3 copy number gain See cases [RCV000143656] Chr12:114268403..133201316 [GRCh38]
Chr12:114706208..133777902 [GRCh37]
Chr12:113190591..132287975 [NCBI36]
Chr12:12q24.21-24.33		 pathogenic
GRCh38/hg38 12q24.31-24.33(chr12:122985202-130714574)x1 copy number loss See cases [RCV000051345] Chr12:122985202..130714574 [GRCh38]
Chr12:123469749..131199119 [GRCh37]
Chr12:122035702..129765072 [NCBI36]
Chr12:12q24.31-24.33		 pathogenic
GRCh38/hg38 12q24.21-24.33(chr12:115131583-133166920)x3 copy number gain See cases [RCV000053689] Chr12:115131583..133166920 [GRCh38]
Chr12:115569388..133743506 [GRCh37]
Chr12:114053771..132253579 [NCBI36]
Chr12:12q24.21-24.33		 pathogenic
GRCh38/hg38 12q24.32-24.33(chr12:126403612-133166920)x3 copy number gain See cases [RCV000053715] Chr12:126403612..133166920 [GRCh38]
Chr12:126888158..133743506 [GRCh37]
Chr12:125454111..132253579 [NCBI36]
Chr12:12q24.32-24.33		 pathogenic
GRCh38/hg38 12q24.32(chr12:128105544-128205233)x3 copy number gain See cases [RCV000140015] Chr12:128105544..128205233 [GRCh38]
Chr12:128590089..128689778 [GRCh37]
Chr12:127156042..127255731 [NCBI36]
Chr12:12q24.32		 benign
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:127
Count of miRNA genes:123
Interacting mature miRNAs:123
Transcripts:ENST00000541258
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage
High
Medium
Low 11 57 1 344 7
Below cutoff 50 65 188 10 69 7 73 36 396 4 65 51 3 24 43

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000541258
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12128,118,211 - 128,121,952 (+)Ensembl
RefSeq Acc Id: ENST00000653338
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12128,118,244 - 128,121,456 (+)Ensembl
RefSeq Acc Id: ENST00000654850
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12128,118,463 - 128,121,952 (+)Ensembl
RefSeq Acc Id: ENST00000662521
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12128,118,212 - 128,123,103 (+)Ensembl
RefSeq Acc Id: ENST00000665570
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12128,116,730 - 128,121,457 (+)Ensembl
RefSeq Acc Id: ENST00000668356
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl12128,120,534 - 128,121,546 (+)Ensembl
RefSeq Acc Id: NR_104648
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812128,118,217 - 128,121,952 (+)NCBI
CHM1_112128,423,904 - 128,427,639 (+)NCBI
T2T-CHM13v2.012128,148,552 - 128,152,287 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC LINC02368 COSMIC
Ensembl Genes ENSG00000256659 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000541258 ENTREZGENE
GTEx ENSG00000256659 GTEx
HGNC ID HGNC:53291 ENTREZGENE
Human Proteome Map LINC02368 Human Proteome Map
NCBI Gene LINC02368 ENTREZGENE
RNAcentral URS0000000B3B RNACentral