Abcc2<sup>TR-</sup> (ATP binding cassette subfamily C member 2;transport deficient mutant ,) - Rat Genome Database

Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Abcc2TR- (ATP binding cassette subfamily C member 2;transport deficient mutant ,) Rattus norvegicus
Analyze
Symbol: Abcc2TR-
Name: ATP binding cassette subfamily C member 2;transport deficient mutant ,
RGD ID: 12792941
Description: Spontaneous mutation occurred on a Wistar Unilever maintained at the Amsterdam Academic Medical Center (AMC). It is a nonsense mutation caused by one bp deletion in the coding region of Abcc2.
ASSOCIATED WITH increased circulating bilirubin level
Type: allele  of Abcc2  
Previously known as: Abcc2TR-
Is Marker For: Strains:   WUN-Abcc2TR-/HsdRrrc  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Adenosine triphosphate-binding cassette subfamily C member 2 is the major transporter of the hepatobiliary imaging agent (99m)Tc-mebrofenin. Bhargava KK, etal., J Nucl Med. 2009 Jul;50(7):1140-6. doi: 10.2967/jnumed.109.062448. Epub 2009 Jun 12.
2. Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene. Paulusma CC, etal., Science 1996 Feb 23;271(5252):1126-8.

Genomics


Related Rat Strains
The following Strains have been annotated to Abcc2TR-


Expression


Sequence

Nucleotide Sequences


Additional Information