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Gene: Ak6 (adenylate kinase 6) Ictidomys tridecemlineatus

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Symbol:

Ak6

Name:

adenylate kinase 6

RGD ID:

12737577

Description:

ENCODES a protein that exhibits adenylate kinase activity (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN nucleoside monophosphate phosphorylation (inferred); ribosomal small subunit biogenesis (inferred); ribosome biogenesis (inferred); FOUND IN centrosome (ortholog); nuclear speck (ortholog); nucleolus (ortholog)

Type:

protein-coding

RefSeq Status:

INFERRED

Previously known as:

adenylate kinase isoenzyme 6

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	AK6 (adenylate kinase 6)	NCBI	Ortholog
Mus musculus (house mouse):	Ak6 (adenylate kinase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Ak6 (adenylate kinase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ak6 (adenylate kinase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	AK6 (adenylate kinase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	AK6 (adenylate kinase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	AK6 (adenylate kinase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	AK6 (adenylate kinase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ak6 (adenylate kinase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	191,315,967 - 191,329,147 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936480	252,435 - 265,605 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936480	252,435 - 265,615 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

nucleoside monophosphate phosphorylation (IEA)

ribosomal small subunit biogenesis (IEA)

ribosome biogenesis (IEA)

rRNA processing (IEA)

Cellular Component

Cajal body (IEA)

centrosome (ISO)

cytoplasm (IEA)

nuclear speck (ISO)

nucleolus (ISO)

nucleoplasm (IEA)

nucleus (IEA)

Molecular Function

adenylate kinase activity (IEA)

ATP binding (IEA)

ATP hydrolysis activity (IEA)

kinase activity (IEA)

nucleotide binding (IEA)

protein binding (ISO)

transferase activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Ak6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	191,315,967 - 191,329,147 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936480	252,435 - 265,605 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936480	252,435 - 265,615 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AK6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	69,350,984 - 69,369,824 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	69,350,984 - 69,370,013 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	68,646,811 - 68,665,651 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Cytogenetic Map	5	q13.2	NCBI
HuRef	5	65,603,597 - 65,621,883 (-)	NCBI		HuRef
CHM1_1	5	68,647,401 - 68,665,684 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	70,176,769 - 70,195,609 (-)	NCBI		T2T-CHM13v2.0

Ak6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	100,787,851 - 100,802,923 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	100,787,487 - 100,802,867 (+)	Ensembl		GRCm39 Ensembl
GRCm38	13	100,651,343 - 100,666,415 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	100,650,979 - 100,666,359 (+)	Ensembl	GRCm38		mm10	GRCm38
Celera	13	104,261,518 - 104,276,058 (+)	NCBI		Celera
Cytogenetic Map	13	D1	NCBI

Ak6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	33,528,388 - 33,540,445 (+)	NCBI		GRCr8
mRatBN7.2	2	31,794,316 - 31,806,375 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	25,576,483 - 25,576,998 (+)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	2	31,794,519 - 31,806,371 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	38,928,842 - 38,940,871 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	36,969,330 - 36,981,235 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	31,827,274 - 31,839,138 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	30,664,407 - 30,676,464 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	30,664,217 - 30,676,464 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	20	27,129,291 - 27,129,806 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	49,824,043 - 49,836,100 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	2	27,807,006 - 27,818,863 (+)	NCBI		Celera
Cytogenetic Map	2	q12	NCBI

Ak6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955575	60,481 - 78,415 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955575	61,082 - 78,415 (-)	NCBI	ChiLan1.0	ChiLan1.0

AK6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	44,549,846 - 44,567,894 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	42,703,471 - 42,721,447 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	44,630,692 - 44,649,166 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	46,201,985 - 46,220,364 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	46,201,985 - 46,220,364 (+)	Ensembl	panpan1.1		panPan2

AK6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	54,390,411 - 54,406,872 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	54,390,411 - 54,406,872 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	51,356,906 - 51,373,134 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	54,901,418 - 54,917,916 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	54,901,418 - 54,917,942 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	51,960,190 - 51,976,409 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	52,735,500 - 52,749,699 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	53,623,775 - 53,640,092 (-)	NCBI		UU_Cfam_GSD_1.0

AK6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	47,480,557 - 47,500,018 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	47,480,556 - 47,499,656 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	51,338,643 - 51,356,750 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AK6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	65,435,848 - 65,456,343 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	65,434,782 - 65,456,000 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666049	14,171,677 - 14,192,710 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ak6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624905	228,706 - 244,656 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla_female_1.0 Ensembl	NW_004624805	2,392,044 - 2,392,637 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624905	228,751 - 244,656 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001286241	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010002273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000026342 ⟹ ENSSTOP00000020626

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936480	252,435 - 265,605 (+)	Ensembl

RefSeq Acc Id:

NM_001286241 ⟹ NP_001273170

RefSeq Status:

INFERRED

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	191,315,967 - 191,329,147 (+)	NCBI
SpeTri2.0	NW_004936480	252,435 - 265,615 (+)	NCBI

Sequence:

show sequence

CTGCCTCCCGCTTCCGGCTCCTCTCTCTAGTGCGCTGAGCGCGTGAGCCTCGGCGCTTGTGCGG
TCGCGGTGGAGGACTATGTTGTTACCGAACATTCTGCTCACCGGTACTCCAGGGGTTGGAAAAA
CTACACTAGGCAAAGAACTTGCATCAAGATCAGGACTGAAATACATTAATGTGGGTGATTTAGC
TCAAGAAGGGCAGTTATATAATGGCTATGATGAAGAGTATGATTGTCCCATTTTAGATGAAGAT
AGAGTAGTTGATGAGTTAGAAAACCAAATGAGAGAAGGTGGAACTATTGTTGATTACCATGGTT
GTGATTTCTTCCCTGAACGCTGGTTTCACATAGTTTTTGTGTTGAGAACAGATAACAGTGAATT
GTACAAAAGACTTGAAACAAGGGGTTATGGTGAGAAGAAATTAAAAGATAACATTCAGTGTGAG
ATTTTTCAAGTTCTTTATGAAGAAGCCGTAGCATCCTACAAAGAAGAAATTGTGCATCAACTGT
CCAGCAATAAACCAGAAGATCTAGAAGATAATATAAATCAGATCCTGAAATGGATTGAGCAGTG
GGTCAAAGATCATAACACTTGACTGGCCACTTTACAGTCACTCTTATTGACACCTTTCTACCCA
CTTCATAGAAATTGTCTACATATTATTAAAATTATTATTAAATAATATTATTAAAATCATGTTG
CAGGCCTAGCAGATGCATAATGTAAAGGTTTGTGCCTGGGTCTCTTTTTCTCCACATGAAAGCT
AAACAATGTCTAATATGAATATAATATTAAAAGTAAAAATTGTCATTTAATGCTTTAGTTACTA
AAAAATAAATATGACCAAAGGAGTTAATATTCTTTATGCTTATTATAGAAGAAAATGCAGATGA
TTTATTAAAAAATAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001273170	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000020626.1
	ENSSTOP00000026702.1
GenBank Protein	KAG3266556	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001273170 ⟸ NM_001286241
- UniProtKB:	I3N8D0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLLPNILLTGTPGVGKTTLGKELASRSGLKYINVGDLAQEGQLYNGYDEEYDCPILDEDRVVDE LENQMREGGTIVDYHGCDFFPERWFHIVFVLRTDNSELYKRLETRGYGEKKLKDNIQCEIFQVL YEEAVASYKEEIVHQLSSNKPEDLEDNINQILKWIEQWVKDHNT hide sequence

Ensembl Acc Id:

ENSSTOP00000020626 ⟸ ENSSTOT00000026342

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000024448	Ensembl, UniProtKB/TrEMBL
	ENSSTOG00000030758	UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000026342.2	UniProtKB/TrEMBL
	ENSSTOT00000033499.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	Adenyl_kinase_AK6	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
NCBI Gene	Ak6	ENTREZGENE
PANTHER	ADENYLATE KINASE ISOENZYME 6	UniProtKB/TrEMBL
	PTHR12595	UniProtKB/TrEMBL
Pfam	AAA_18	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A287CZG8_ICTTR	UniProtKB/TrEMBL
	I3N8D0	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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