Pex2 (peroxisomal biogenesis factor 2) - Rat Genome Database

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Gene: Pex2 (peroxisomal biogenesis factor 2) Ictidomys tridecemlineatus
Analyze
Symbol: Pex2
Name: peroxisomal biogenesis factor 2
RGD ID: 12737309
Description: ENCODES a protein that exhibits metal ion binding (inferred); transferase activity (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN bile acid biosynthetic process (ortholog); cholesterol homeostasis (ortholog); nervous system development (ortholog); ASSOCIATED WITH genetic disease (ortholog); infantile Refsum disease (ortholog); peroxisomal biogenesis disorder (ortholog); FOUND IN peroxisomal membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: peroxisomal biogenesis factor 2, transcript variant X1; peroxisomal biogenesis factor 2, transcript variant X2; peroxisomal biogenesis factor 2, transcript variant X4; peroxisomal biogenesis factor 2, transcript variant X5; peroxisome biogenesis factor 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530354,180,390 - 54,197,777 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367021,573,650 - 1,591,004 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367021,573,616 - 1,626,323 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Pex2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530354,180,390 - 54,197,777 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367021,573,650 - 1,591,004 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367021,573,616 - 1,626,323 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PEX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38876,980,258 - 77,001,044 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl876,980,258 - 77,001,044 (-)EnsemblGRCh38hg38GRCh38
GRCh37877,892,494 - 77,913,280 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36878,055,049 - 78,075,079 (-)NCBINCBI36Build 36hg18NCBI36
Build 34878,057,712 - 78,074,994NCBI
Celera873,885,870 - 73,906,661 (-)NCBICelera
Cytogenetic Map8q21.13NCBI
HuRef873,378,964 - 73,399,755 (-)NCBIHuRef
CHM1_1877,944,088 - 77,964,880 (-)NCBICHM1_1
T2T-CHM13v2.0877,409,691 - 77,430,483 (-)NCBIT2T-CHM13v2.0
Pex2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3935,625,248 - 5,643,655 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl35,625,248 - 5,641,299 (-)EnsemblGRCm39 Ensembl
GRCm3835,560,188 - 5,578,596 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl35,560,188 - 5,576,239 (-)EnsemblGRCm38mm10GRCm38
MGSCv3735,560,188 - 5,576,239 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3635,543,577 - 5,559,201 (-)NCBIMGSCv36mm8
Celera35,637,555 - 5,653,606 (-)NCBICelera
Cytogenetic Map3A1NCBI
cM Map31.96NCBI
Pex2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8297,957,479 - 97,973,767 (+)NCBIGRCr8
mRatBN7.2296,050,380 - 96,072,928 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl296,045,958 - 96,073,404 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2102,587,325 - 102,603,512 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02100,708,411 - 100,724,598 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0295,763,317 - 95,779,508 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0298,251,756 - 98,269,185 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl298,252,925 - 98,269,184 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02117,990,545 - 118,007,746 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4298,361,891 - 98,378,715 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1298,306,852 - 98,323,677 (+)NCBI
Celera291,566,959 - 91,583,216 (+)NCBICelera
Cytogenetic Map2q23NCBI
Pex2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554443,811,973 - 3,830,666 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554443,811,972 - 3,830,666 (+)NCBIChiLan1.0ChiLan1.0
PEX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2792,717,778 - 92,735,460 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1868,345,570 - 68,363,805 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0873,508,349 - 73,526,560 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1875,145,061 - 75,163,338 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl875,146,255 - 75,147,172 (-)Ensemblpanpan1.1panPan2
PEX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12924,943,563 - 24,960,834 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2925,206,108 - 25,223,363 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02925,055,730 - 25,073,096 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2925,055,743 - 25,073,046 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12925,130,967 - 25,148,201 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02925,148,141 - 25,165,401 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02925,500,349 - 25,517,613 (-)NCBIUU_Cfam_GSD_1.0
PEX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl459,252,337 - 59,270,116 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1459,252,330 - 59,270,117 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2464,716,680 - 64,745,314 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PEX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1872,513,975 - 72,532,399 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl872,514,307 - 72,517,003 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603968,748,476 - 68,767,273 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pex2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474414,240,570 - 14,245,183 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474414,227,430 - 14,245,082 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000022784   ⟹   ENSSTOP00000023910
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049367021,573,650 - 1,591,004 (+)Ensembl
RefSeq Acc Id: XM_005338045   ⟹   XP_005338102
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530354,180,390 - 54,197,777 (+)NCBI
SpeTri2.0NW_0049367021,573,619 - 1,590,790 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040293926   ⟹   XP_040149860
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530354,194,387 - 54,197,777 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005338102   ⟸   XM_005338045
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_040149860   ⟸   XM_040293926
- Peptide Label: isoform X2
- UniProtKB: I3NHR3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000023910   ⟸   ENSSTOT00000022784
Protein Domains
RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000025900 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000022784.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro PEX2/10 UniProtKB/TrEMBL
  Pex_N UniProtKB/TrEMBL
  RING-HC_PEX2 UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
NCBI Gene Pex2 ENTREZGENE
PANTHER PEROXISOME BIOGENESIS FACTOR 2 UniProtKB/TrEMBL
  PEROXISOME BIOGENESIS FACTOR 2 UniProtKB/TrEMBL
Pfam Pex2_Pex12 UniProtKB/TrEMBL
PROSITE ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt I3NHR3 ENTREZGENE, UniProtKB/TrEMBL