Ahrr (aryl-hydrocarbon receptor repressor)

Gene: Ahrr (aryl-hydrocarbon receptor repressor) Ictidomys tridecemlineatus

Analyze

Symbol:

Ahrr

Name:

aryl-hydrocarbon receptor repressor

RGD ID:

12735232

Description:

ENCODES a protein that exhibits nuclear receptor activity (inferred); transcription cis-regulatory region binding (inferred); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); nitric oxide metabolic process (ortholog); ASSOCIATED WITH dopamine transporter deficiency syndrome (ortholog); genetic disease (ortholog); hypertension (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

aryl hydrocarbon receptor repressor

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	244,863,247 - 244,913,881 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936815	1,031,696 - 1,045,032 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

dopamine transporter deficiency syndrome (ISO)

genetic disease (ISO)

hypertension (ISO)

idiopathic pulmonary fibrosis (ISO)

Prenatal Exposure Delayed Effects (ISO)

prostate cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular receptor signaling pathway (IEA)

negative regulation of DNA-templated transcription (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

nitric oxide metabolic process (ISO)

positive regulation of protein sumoylation (ISO)

regulation of transcription by RNA polymerase II (IEA)

response to xenobiotic stimulus (IEA)

xenobiotic metabolic process (IEA)

Cellular Component

aryl hydrocarbon receptor complex (IEA)

cytosol (ISO)

nucleoplasm (ISO)

nucleus (IEA)

Molecular Function

nuclear receptor activity (IEA)

protein binding (ISO)

transcription cis-regulatory region binding (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Ahrr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	244,863,247 - 244,913,881 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936815	1,031,696 - 1,045,032 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AHRR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	321,714 - 438,285 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	321,714 - 438,291 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	321,829 - 438,400 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	357,291 - 491,406 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	357,290 - 488,225	NCBI
Celera	5	402,630 - 536,558 (+)	NCBI		Celera
Cytogenetic Map	5	p15.33	NCBI
HuRef	5	291,576 - 426,497 (+)	NCBI		HuRef
CHM1_1	5	304,156 - 437,792 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	312,595 - 433,546 (+)	NCBI		T2T-CHM13v2.0

Ahrr
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	74,359,237 - 74,440,450 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	74,359,237 - 74,440,450 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	74,211,118 - 74,292,331 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	74,211,118 - 74,292,331 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	74,348,566 - 74,429,757 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	74,677,120 - 74,758,311 (-)	NCBI		MGSCv36	mm8
Celera	13	76,540,694 - 76,621,755 (-)	NCBI		Celera
Cytogenetic Map	13	C1	NCBI
cM Map	13	40.15	NCBI

Ahrr
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	30,822,219 - 30,917,251 (+)	NCBI		GRCr8
mRatBN7.2	1	28,993,634 - 29,088,673 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	28,993,634 - 29,088,673 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	28,794,922 - 28,890,469 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	34,794,780 - 34,890,331 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	28,995,546 - 29,091,090 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	31,603,297 - 31,698,329 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	31,603,297 - 31,698,329 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	33,029,445 - 33,123,740 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	29,797,025 - 29,894,912 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	27,645,404 - 27,740,439 (+)	NCBI		Celera
Cytogenetic Map	1	p11	NCBI

Ahrr
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955504	122,562 - 189,297 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955504	121,739 - 191,871 (+)	NCBI	ChiLan1.0	ChiLan1.0

AHRR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	541,573 - 661,263 (+)	NCBI		NHGRI_mPanPan1-v2
PanPan1.1 Ensembl	5	436,542 - 567,310 (+)	Ensembl	panpan1.1		panPan2

AHRR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	11,820,119 - 11,865,681 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	11,820,473 - 11,867,821 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	16,334,010 - 16,414,703 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	11,722,171 - 11,802,722 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	11,722,507 - 11,802,951 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	11,775,636 - 11,846,567 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	11,761,424 - 11,842,118 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	11,963,533 - 12,044,089 (-)	NCBI		UU_Cfam_GSD_1.0

AHRR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	79,730,926 - 79,810,188 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	79,730,920 - 79,810,183 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

AHRR
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	220,523 - 329,973 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	243,026 - 326,722 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666064	27,347,915 - 27,457,932 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ahrr
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624751	139,085 - 209,546 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624751	128,596 - 212,170 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021720510	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010002273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_021720510 ⟹ XP_021576185

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	244,863,247 - 244,913,881 (-)	NCBI
SpeTri2.0	NW_004936815	1,031,696 - 1,045,032 (-)	NCBI

Sequence:

show sequence

CTCAATGGCTTTGCCCTGGTCGTGAGTGCCGACGGGATGATCTTCTACGCCTCGCCCACCATTG
TGGACTATCTGGGCTTCCACCAGACGGATGTGATGCACCAAAACATTTATGACTACATCCATGT
CGAGGACCGCCAGGACTTCTGCCGGCAGCTGCACTGGGCCATGGACCCCCCCCAGGGGCTCGGC
CAGCCCCCGCGCCCAGACACAGGAGATGACAGTGTGCTGCGGAGGCTGCTCAGGGCCCAGGAGG
GAGGCTCTGGCTCTCCCACCGAGTACTCAGCCTTCCTGACCCGGTGCTTCGTCTGCCGCGTGCG
CTGCCTGCTGGATAGCACCTCTGGCTTTCTGATGATGCAGTTTCAAGGGAAACTAAAATTCTTG
CTGGGTCAGAAGAGGAAGGCACCATCAGGAAGCATCCTGCCCCCGCGGCTCTCCCTGTTCTGCA
CCGTGGCGCCTGTCCTCCTGCCGGCCTTGGCAGAGGTGAAGATGAAGGGTGCGTTTCTGAGGGC
CAAGCACAGGGTGGACACCTCGGCCACAGTGGACCCCAGGGCCCAGGCCACCCCAGCTCTGTGT
GGACCAGACCCTCGTGCAAAGCCCAGCTTCACTGCAGGAAGCAGCAATGGTGAAAACTGCGTTC
CCCTGTTCAGGTCACAGATGGACACTGGCCACTGGACCCGGGCTCCCAGCAGGGCCCTGTGCCT
GTGCCTCAAGGGTGGCCCTGAACTCATCCTGGACCCCACAGGGGCTGCAGGCGACCGGGAAGAC
GCAGAGCAGGAGAGAGTGCTGAGCGGCTGTGCTGCAGGGAGAGGCTGGCGGGAGACACAGGCAC
ACAACTGCTGCTGGGAGACGCCAACACCCATGAGGCACCCCAGCTGGACGGCAGACAAGCGAGA
CAAGCCAAAGCCACAGCCCACCAGGATTGAGCGGCCATCCATGCGCGGCGTGTCCCACGTCTCC
TGCCTGCCTTACCCAGAAGCCCAGGGCATGCTCAGTACCAGTGGCACAACCCCCTTCAGAAGTT
CACCCCTCTCGCCCCTGCCAGGCTCTCCCCACAGTGCCTACTGCAGCAGGCCAAGCAGACCCCT
ACGGGACCTCCAGCAGGAACAGGGGCATCCTCCCTGCCACACCCTGCAGAGCGGTCTGGAGAAG
AGGCTCCCTGTGCCCGGAGCACAGTGCTTCCCAGCTGGGGGCTACTCTCCTGAGGATGCCAAGT
TGCCCGGCCTGCTGGTGTCCCCAGGGGCCCCACGCAGTCCAGCCCTGTTGCTTGAAGTGCCAAT
CAAGATGGAAAATGACTCTGGGTCTGAGGATGCAGTGGACATCTGCACCCCCAGCCAGGTGTGG
CTGGGAGCCAGCAACATGGCCAAGAGACAGCTGGTCACTTTTCCTACCAGGATGCACCTGAAGA
CAGAGTTGGACTGCAGGCACCAGGTCCACCCCCCGCACCTCGTGCATGGTGTGGTAGGGGCTCA
CCCCCACAGCCAGGCCACCACTGAAGCCAGCAGGGAACTTGTTCCCTTCTTCCCTTCACCCTGC
GCCTGCCTGGAGCCAGAGCCTCCCCTCCACCTCTGCACACCCAGCTGCCCCGAGCACCAGCACC
TGGCTCGGGGCTGTGACTGCAGAGCTCCCAGGGCTGCTGCTGTGGTCAAGCGCGAGCCCCTGGA
CTCGCCCCCCTGGGCTGCTGCTCCCGGCCAGGGAGCCGTGCCCAGGTTGTTTCCCAAAAGCACC
TCAGCCTTCCTGCCCTAA

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Protein Sequences


Protein RefSeqs	XP_021576185	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000021183.2
GenBank Protein	KAG3266940	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_021576185 ⟸ XM_021720510

- UniProtKB:

I3N9Y6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MIFYASPTIVDYLGFHQTDVMHQNIYDYIHVEDRQDFCRQLHWAMDPPQGLGQPPRPDTGDDSV
LRRLLRAQEGGSGSPTEYSAFLTRCFVCRVRCLLDSTSGFLMMQFQGKLKFLLGQKRKAPSGSI
LPPRLSLFCTVAPVLLPALAEVKMKGAFLRAKHRVDTSATVDPRAQATPALCGPDPRAKPSFTA
GSSNGENCVPLFRSQMDTGHWTRAPSRALCLCLKGGPELILDPTGAAGDREDAEQERVLSGCAA
GRGWRETQAHNCCWETPTPMRHPSWTADKRDKPKPQPTRIERPSMRGVSHVSCLPYPEAQGMLS
TSGTTPFRSSPLSPLPGSPHSAYCSRPSRPLRDLQQEQGHPPCHTLQSGLEKRLPVPGAQCFPA
GGYSPEDAKLPGLLVSPGAPRSPALLLEVPIKMENDSGSEDAVDICTPSQVWLGASNMAKRQLV
TFPTRMHLKTELDCRHQVHPPHLVHGVVGAHPHSQATTEASRELVPFFPSPCACLEPEPPLHLC
TPSCPEHQHLARGCDCRAPRAAAVVKREPLDSPPWAAAPGQGAVPRLFPKSTSAFLP

hide sequence

Protein Domains

PAS

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000019733	UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000025445.2	UniProtKB/TrEMBL
Gene3D-CATH	PAS domain	UniProtKB/TrEMBL
InterPro	AHR/AHRR	UniProtKB/TrEMBL
	PAS	UniProtKB/TrEMBL
	PAS-like_dom_sf	UniProtKB/TrEMBL
NCBI Gene	Ahrr	ENTREZGENE
PANTHER	PTHR10649	UniProtKB/TrEMBL
	PTHR10649:SF3	UniProtKB/TrEMBL
PROSITE	PAS	UniProtKB/TrEMBL
Superfamily-SCOP	SSF55785	UniProtKB/TrEMBL
UniProt	I3N9Y6	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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