Ca12 (carbonic anhydrase 12) - Rat Genome Database

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Gene: Ca12 (carbonic anhydrase 12) Ictidomys tridecemlineatus
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Symbol: Ca12
Name: carbonic anhydrase 12
RGD ID: 12731898
Description: ENCODES a protein that exhibits carbonate dehydratase activity (ortholog); INVOLVED IN chloride ion homeostasis (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); colon cancer (ortholog); hypertrophic cardiomyopathy (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640106,028,826 - 106,081,389 (-)NCBI
SpeTri2.0NW_00493647123,876,889 - 23,929,720 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

Genomics

Comparative Map Data
Ca12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640106,028,826 - 106,081,389 (-)NCBI
SpeTri2.0NW_00493647123,876,889 - 23,929,720 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1563,321,378 - 63,381,846 (-)EnsemblGRCh38hg38GRCh38
GRCh381563,321,378 - 63,381,846 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371563,613,577 - 63,674,045 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361561,402,783 - 61,461,128 (-)NCBINCBI36hg18NCBI36
Celera1540,494,364 - 40,552,718 (-)NCBI
Cytogenetic Map15q22.2NCBI
HuRef1540,438,444 - 40,496,766 (-)NCBIHuRef
CHM1_11563,732,628 - 63,793,404 (-)NCBICHM1_1
Car12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39966,619,026 - 66,674,127 (+)NCBIGRCm39mm39
GRCm39 Ensembl966,620,968 - 66,674,127 (+)Ensembl
GRCm38966,712,296 - 66,766,845 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl966,713,686 - 66,766,845 (+)EnsemblGRCm38mm10GRCm38
MGSCv37966,561,493 - 66,614,652 (+)NCBIGRCm37mm9NCBIm37
MGSCv36966,512,886 - 66,565,989 (+)NCBImm8
Celera963,948,029 - 64,000,964 (+)NCBICelera
Cytogenetic Map9CNCBI
Ca12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2867,274,739 - 67,330,428 (+)NCBI
Rnor_6.0 Ensembl872,405,748 - 72,460,240 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0872,405,770 - 72,461,425 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0872,071,988 - 72,127,646 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4871,017,732 - 71,070,729 (+)NCBIRGSC3.4rn4RGSC3.4
Celera866,660,144 - 66,713,076 (+)NCBICelera
Cytogenetic Map8q24NCBI
Ca12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545011,943,340 - 11,975,928 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545011,927,730 - 11,975,553 (+)NCBIChiLan1.0ChiLan1.0
CA12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11560,565,592 - 60,624,008 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1560,565,592 - 60,624,008 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01542,270,188 - 42,328,952 (-)NCBIMhudiblu_PPA_v0panPan3
CA12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13027,903,460 - 27,957,162 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3027,905,837 - 27,957,742 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3027,822,431 - 27,876,096 (-)NCBI
ROS_Cfam_1.03028,075,321 - 28,129,041 (-)NCBI
UMICH_Zoey_3.13028,012,749 - 28,066,343 (-)NCBI
UNSW_CanFamBas_1.03028,074,625 - 28,128,260 (-)NCBI
UU_Cfam_GSD_1.03028,311,867 - 28,365,995 (-)NCBI
CA12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1108,649,271 - 108,710,651 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11108,649,277 - 108,710,658 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21119,822,275 - 119,904,112 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CA12
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12620,162,706 - 20,221,680 (+)NCBI
ChlSab1.1 Ensembl2620,162,926 - 20,224,502 (+)Ensembl
Ca12
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247819,140,753 - 9,195,651 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_013360098   ⟹   XP_013215552
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640106,031,301 - 106,081,389 (-)NCBI
SpeTri2.0NW_00493647123,876,889 - 23,929,720 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021727280   ⟹   XP_021582955
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640106,031,301 - 106,081,389 (-)NCBI
SpeTri2.0NW_00493647123,876,889 - 23,929,720 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021727284   ⟹   XP_021582959
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640106,031,301 - 106,081,389 (-)NCBI
SpeTri2.0NW_00493647123,876,889 - 23,929,720 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021727286   ⟹   XP_021582961
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_00493647123,876,889 - 23,929,720 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021727289   ⟹   XP_021582964
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640106,031,301 - 106,081,389 (-)NCBI
SpeTri2.0NW_00493647123,876,889 - 23,929,720 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040275977   ⟹   XP_040131911
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640106,028,826 - 106,081,389 (-)NCBI
RefSeq Acc Id: XM_040275978   ⟹   XP_040131912
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640106,028,826 - 106,081,389 (-)NCBI
RefSeq Acc Id: XM_040275979   ⟹   XP_040131913
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640106,039,123 - 106,081,389 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_013215552   ⟸   XM_013360098
- Peptide Label: isoform X3
- UniProtKB: A0A287D2F7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021582964   ⟸   XM_021727289
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_021582959   ⟸   XM_021727284
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_021582961   ⟸   XM_021727286
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_021582955   ⟸   XM_021727280
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_040131912   ⟸   XM_040275978
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040131911   ⟸   XM_040275977
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040131913   ⟸   XM_040275979
- Peptide Label: isoform X7
Protein Domains
Alpha-carbonic anhydrase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000016051 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000014368 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOP00000027695 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000016054 UniProtKB/TrEMBL
  ENSSTOT00000036297 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro Carbonic_anhydrase_a UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class_CS UniProtKB/TrEMBL
  Carbonic_anhydrase_a_sf UniProtKB/TrEMBL
  Carbonic_anhydrase_CA12 UniProtKB/TrEMBL
NCBI Gene Ca12 ENTREZGENE
PANTHER PTHR18952 UniProtKB/TrEMBL
  PTHR18952:SF19 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_1 UniProtKB/TrEMBL
  ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt A0A287D2F7 ENTREZGENE, UniProtKB/TrEMBL
  I3MQU5_ICTTR UniProtKB/TrEMBL