Rest (RE1 silencing transcription factor) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Rest (RE1 silencing transcription factor) Ictidomys tridecemlineatus
Analyze
Symbol: Rest
Name: RE1 silencing transcription factor
RGD ID: 12730142
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN auditory receptor cell stereocilium organization (ortholog); cardiac muscle cell myoblast differentiation (ortholog); cellular response to electrical stimulus (ortholog); ASSOCIATED WITH autosomal dominant nonsyndromic deafness 27 (ortholog); genetic disease (ortholog); Gingival Fibromatosis 1 (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: RE1-silencing transcription factor
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528527,258,819 - 27,303,941 (-)NCBI
SpeTri2.0NW_00493648219,018,454 - 19,040,438 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
auditory receptor cell stereocilium organization  (ISO)
cardiac muscle cell myoblast differentiation  (ISO)
cellular response to electrical stimulus  (ISO)
cellular response to glucocorticoid stimulus  (ISO)
cellular response to xenobiotic stimulus  (ISO)
detection of mechanical stimulus involved in sensory perception of sound  (ISO)
hematopoietic progenitor cell differentiation  (ISO)
histone H4 deacetylation  (ISO)
modification of synaptic structure  (ISO)
negative regulation by host of viral transcription  (ISO)
negative regulation of aldosterone biosynthetic process  (ISO)
negative regulation of amniotic stem cell differentiation  (ISO)
negative regulation of calcium ion-dependent exocytosis  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of cortisol biosynthetic process  (ISO)
negative regulation of dense core granule biogenesis  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of insulin secretion  (ISO)
negative regulation of mesenchymal stem cell differentiation  (ISO)
negative regulation of neurogenesis  (ISO)
negative regulation of neuron differentiation  (ISO)
negative regulation of oxidative stress-induced neuron death  (ISO)
negative regulation of pri-miRNA transcription by RNA polymerase II  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
negative regulation of transcription regulatory region DNA binding  (ISO)
negative regulation of transcription, DNA-templated  (ISO)
neuromuscular process controlling balance  (ISO)
neuron differentiation  (ISO)
neuronal stem cell population maintenance  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of neuron differentiation  (ISO)
positive regulation of oxidative stress-induced neuron death  (ISO)
positive regulation of stem cell population maintenance  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
regulation of alternative mRNA splicing, via spliceosome  (ISO)
regulation of gene expression  (ISO)
regulation of osteoblast differentiation  (ISO)
regulation of oxidative stress-induced neuron death  (ISO)
regulation of transcription, DNA-templated  (ISO)
response to hypoxia  (ISO)
response to ischemia  (ISO)
somatic stem cell population maintenance  (ISO)

Cellular Component

References

Genomics

Comparative Map Data
Rest
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528527,258,819 - 27,303,941 (-)NCBI
SpeTri2.0NW_00493648219,018,454 - 19,040,438 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
REST
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl456,907,876 - 56,966,808 (+)EnsemblGRCh38hg38GRCh38
GRCh38456,907,900 - 56,935,847 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37457,774,066 - 57,802,010 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36457,468,799 - 57,493,097 (+)NCBINCBI36hg18NCBI36
Build 34457,614,969 - 57,639,268NCBI
Celera455,279,985 - 55,307,950 (+)NCBI
Cytogenetic Map4q12NCBI
HuRef453,727,986 - 53,755,535 (+)NCBIHuRef
CHM1_1457,809,465 - 57,837,418 (+)NCBICHM1_1
Rest
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39577,413,273 - 77,434,279 (+)NCBIGRCm39mm39
GRCm39 Ensembl577,413,338 - 77,434,279 (+)Ensembl
GRCm38577,265,494 - 77,286,432 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl577,265,491 - 77,286,432 (+)EnsemblGRCm38mm10GRCm38
MGSCv37577,694,519 - 77,712,722 (+)NCBIGRCm37mm9NCBIm37
MGSCv36578,342,716 - 78,357,759 (+)NCBImm8
Celera574,535,211 - 74,550,959 (+)NCBICelera
Cytogenetic Map5C3.3NCBI
Rest
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21430,859,109 - 30,879,828 (-)NCBI
Rnor_6.0 Ensembl1433,134,511 - 33,164,141 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01433,131,985 - 33,152,019 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01432,925,741 - 32,951,551 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41433,136,046 - 33,151,142 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11433,136,045 - 33,151,142 (-)NCBI
Celera1430,181,687 - 30,196,879 (-)NCBICelera
Cytogenetic Map14p11NCBI
REST
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1473,556,780 - 73,582,419 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl473,526,085 - 73,582,242 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0466,984,466 - 67,012,301 (-)NCBIMhudiblu_PPA_v0panPan3
REST
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11349,041,082 - 49,062,596 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1349,041,047 - 49,059,388 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1348,930,954 - 48,953,349 (+)NCBI
ROS_Cfam_1.01349,654,746 - 49,677,219 (+)NCBI
UMICH_Zoey_3.11349,327,159 - 49,349,567 (+)NCBI
UNSW_CanFamBas_1.01348,856,606 - 48,878,993 (+)NCBI
UU_Cfam_GSD_1.01349,801,275 - 49,823,781 (+)NCBI
REST
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl856,035,150 - 56,215,013 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1856,035,182 - 56,061,140 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2857,440,573 - 57,466,453 (-)NCBISscrofa10.2Sscrofa10.2susScr3
REST
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1711,749,312 - 11,776,103 (-)NCBI
ChlSab1.1 Ensembl711,749,168 - 11,773,340 (-)Ensembl
Vero_WHO_p1.0NW_02366606612,388,814 - 12,415,743 (-)NCBI
Rest
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476112,464,243 - 12,495,294 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005320033   ⟹   XP_005320090
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440528527,258,819 - 27,279,804 (-)NCBI
SpeTri2.0NW_00493648219,018,454 - 19,040,438 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040292375   ⟹   XP_040148309
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440528527,258,819 - 27,303,941 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005320090 (Get FASTA)   NCBI Sequence Viewer  
  XP_040148309 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3276573 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005320090   ⟸   XM_005320033
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_040148309   ⟸   XM_040292375
- Peptide Label: isoform X1
Protein Domains
C2H2-type


Additional Information

Database Acc Id Source(s)
NCBI Gene Rest ENTREZGENE