Tspan15 (tetraspanin 15) - Rat Genome Database

Name: Tspan15
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Tspan15 (tetraspanin 15) Ictidomys tridecemlineatus

Analyze

Symbol:

Tspan15

Name:

tetraspanin 15

RGD ID:

12724834

Description:

ENCODES a protein that exhibits enzyme binding (inferred); INVOLVED IN regulation of Notch signaling pathway (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cell junction (inferred); cell surface (inferred); cytosol (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

tetraspanin-15

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TSPAN15 (tetraspanin 15)	NCBI	Ortholog
Mus musculus (house mouse):	Tspan15 (tetraspanin 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Tspan15 (tetraspanin 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tspan15 (tetraspanin 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TSPAN15 (tetraspanin 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TSPAN15 (tetraspanin 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TSPAN15 (tetraspanin 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TSPAN15 (tetraspanin 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tspan15 (tetraspanin 15)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	60,488,966 - 60,529,616 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936521	8,979,541 - 9,022,387 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936521	8,981,691 - 9,022,336 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of Notch signaling pathway (IEA)

protein localization to plasma membrane (IEA)

protein maturation (IEA)

regulation of membrane protein ectodomain proteolysis (IEA)

regulation of Notch signaling pathway (ISO)

Cellular Component

cell junction (IEA)

cell surface (IEA)

cytosol (IEA)

intracellular membrane-bounded organelle (IEA)

membrane (IEA)

nuclear body (IEA)

plasma membrane (IEA)

tetraspanin-enriched microdomain (IEA)

Molecular Function

enzyme binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Tspan15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	60,488,966 - 60,529,616 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936521	8,979,541 - 9,022,387 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936521	8,981,691 - 9,022,336 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TSPAN15
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	69,451,465 - 69,549,508 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	69,451,465 - 69,507,666 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	71,211,221 - 71,267,422 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	70,881,232 - 70,937,429 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	70,881,231 - 70,937,429	NCBI
Celera	10	64,487,632 - 64,543,834 (+)	NCBI		Celera
Cytogenetic Map	10	q22.1	NCBI
HuRef	10	65,211,006 - 65,267,237 (+)	NCBI		HuRef
CHM1_1	10	71,492,976 - 71,549,176 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	70,319,512 - 70,417,621 (+)	NCBI		T2T-CHM13v2.0

Tspan15
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	62,021,175 - 62,067,055 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	62,021,175 - 62,067,030 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	62,185,396 - 62,231,276 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	62,185,396 - 62,231,251 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	61,648,144 - 61,693,966 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	61,582,724 - 61,626,524 (-)	NCBI		MGSCv36	mm8
Celera	10	63,288,374 - 63,334,469 (-)	NCBI		Celera
Cytogenetic Map	10	B4	NCBI
cM Map	10	32.36	NCBI

Tspan15
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	30,673,271 - 30,717,651 (-)	NCBI		GRCr8
mRatBN7.2	20	30,130,528 - 30,174,912 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	30,130,530 - 30,174,930 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	31,141,470 - 31,185,856 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	30,532,371 - 30,576,751 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	31,275,155 - 31,319,408 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	31,812,558 - 31,857,191 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	31,813,192 - 31,857,097 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	33,606,531 - 33,648,168 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	20	31,553,858 - 31,597,270 (-)	NCBI		Celera
Cytogenetic Map	20	q11	NCBI

Tspan15
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	21,641,377 - 21,688,007 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	21,643,018 - 21,687,355 (-)	NCBI	ChiLan1.0	ChiLan1.0

TSPAN15
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	81,599,118 - 81,661,203 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	81,604,436 - 81,666,524 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	65,919,622 - 65,976,449 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	68,450,315 - 68,507,151 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	68,450,318 - 68,507,151 (+)	Ensembl	panpan1.1		panPan2

TSPAN15
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	20,556,981 - 20,607,934 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	20,556,689 - 20,607,265 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	20,686,618 - 20,737,576 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	20,828,793 - 20,879,019 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	20,828,774 - 20,887,623 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	20,728,955 - 20,779,317 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	20,932,964 - 20,983,340 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	21,276,326 - 21,327,286 (+)	NCBI		UU_Cfam_GSD_1.0

TSPAN15
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	72,468,914 - 72,555,080 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	72,501,289 - 72,555,084 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

TSPAN15
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	61,813,896 - 61,869,057 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	61,813,686 - 61,868,987 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	22,553,290 - 22,608,436 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tspan15
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	3,703,108 - 3,750,576 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	3,703,087 - 3,779,789 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005325958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040272155	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010002273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000002513 ⟹ ENSSTOP00000002246

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936521	8,979,541 - 9,022,387 (-)	Ensembl

RefSeq Acc Id:

XM_005325958 ⟹ XP_005326015

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	60,488,966 - 60,529,616 (-)	NCBI
SpeTri2.0	NW_004936521	8,981,691 - 9,022,336 (-)	NCBI

Sequence:

show sequence

GTCCGGAAGAGAGCGCTGGTAACTGGGCGGGCCGCCGGGTAGCCTCAGGTGGAGCCTGGAGCAG
TGGCCAAGGAACGGAGCCCGAACCCTGAGTCCCCGAAGCTCCGAATCCCCGAATCCCTGCACGG
GGACCCGCCAGGATGCCCCGCGGGGACTCGGAGCAGGTGCGCTACTGCGCGCGCTTCTCCTATC
TCTGGCTTAAGTTCTCGCTCATCATCTACTCGACGGTGTTCTGGCTCATCGGGGCCCTGGTGCT
GTCTGTGGGGATCTACGCCGAGGTGGAGCGGCAGAAGTACAAGACCCTGGAGAGTGCCTTCCTG
GCGCCCGCCATCATCCTCATCCTCCTGGGGGTGGTCATGTTCCTGGTCTCCTTCGTGGGCGTGC
TGGCCTCCCTGCGGGACAACCTGTACCTCCTCCAGGCGTTCATGTACATCCTTGGCATCTGCCT
CATCATGGAGCTCATTGGTGGCGTGGTGGCCTTGATCTTCCGGAACCAGACCATCAACTTTCTG
AACGACAACATCCGTCGAGGGATCGAGAACTACTACGACGACCTGGACTTCAAGAACATCATGG
ACTTCGTTCAGAAGCAGTTCAAGTGCTGTGGCGGGGAGGACTACCGAGACTGGAGCAAGAACCA
GTACCACGACTGCAGCGCCCCCGGGCCGCTGGCCTGCGGGGTGCCCTACACCTGCTGCTTCAGA
AACACGACAGATGTTGTCAACACCATGTGCGGCTACAAAACCATCGACAAGGAGCGCCTCAGTG
TGCAGGACGTCATCTACGTGCGAGGCTGCACCAACGCTGTGCTCATCTGGTTCATGGATAACTA
CACCATCATGGCGGGCCTCCTGCTGGGCATCCTGCTCCCCCAGTTCTTGGGGGTGCTGCTGACG
CTCCTGTACATCACCCGCGTGGAGGACATCATCATGGAGCATTCTGTCACCGACGGACTTCTGG
GCCCGGACGCCAAGCCCAGCGCGGACACAGCGGGCACAGGCTGCTGCTTGTGCTACCCCAATTA
GGGCCAGGGCCTGGACACCCACTCCAGCAGGACCTGGCTGGGTGGCACCTCTCAGTCCACTTAG
GGGCTGGACAGGACTGCACCACGGCCCTGTGCCCGGGTGGAGTGCCCCTGTGGACGGCTTCTCC
AGGCCGCACACTCTGGGTTCCATGCCCACTCTGCCAGGAGAGAGAGCGTGGCGTCCCTGCTCTG
GATCTGGGCCATGAGGGAAAGAGGAACTTGGGGCTCAGCTCGGGGCCCACTGTATTTCCGGCGG
TGCCCTGGGCTTGCGGTCAGTAGGCCCCTTCAAGGGCAGTTCTGCTGTGATTTGCCAGTTTGGG
GAGACAGTGGCGGGAGGGGCAAGGGGTAGCCCTCCCACGCCCCAGATGAGGTCGGGCCATTTCT
CAGCCTCCGTAGGTGCCTTCAGCCCTCTGCAGGGGCAGCTGTTTTGCTGACCTGTTTTCTATGT
GAGTTTTGTAACATTCATGTTCTGTGCAGAGTTCACAGGACTTTCTGACTGTGCAGAGCCGGGC
ATTTTCCTGCTTTGGCTCCAAGTCAGTTCATTAATCAAACAATAAAGACACGATTTTTTTTTTT
T

hide sequence

RefSeq Acc Id:

XM_040272155 ⟹ XP_040128089

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	60,490,329 - 60,529,606 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005326015	(Get FASTA)	NCBI Sequence Viewer
	XP_040128089	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000002246.3
GenBank Protein	KAG3264784	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005326015 ⟸ XM_005325958
- Peptide Label:	isoform X1
- UniProtKB:	I3M0K2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPRGDSEQVRYCARFSYLWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAFLAPAI ILILLGVVMFLVSFVGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALIFRNQTINFLNDNI RRGIENYYDDLDFKNIMDFVQKQFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCFRNTTD VVNTMCGYKTIDKERLSVQDVIYVRGCTNAVLIWFMDNYTIMAGLLLGILLPQFLGVLLTLLYI TRVEDIIMEHSVTDGLLGPDAKPSADTAGTGCCLCYPN hide sequence

RefSeq Acc Id:	XP_040128089 ⟸ XM_040272155
- Peptide Label:	isoform X2

RefSeq Acc Id:

ENSSTOP00000002246 ⟸ ENSSTOT00000002513

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000002523	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000002513.3	UniProtKB/TrEMBL
Gene3D-CATH	1.10.1450.10	UniProtKB/TrEMBL
InterPro	Tetraspanin/Peripherin	UniProtKB/TrEMBL
	Tetraspanin_animals	UniProtKB/TrEMBL
	Tetraspanin_EC2_sf	UniProtKB/TrEMBL
NCBI Gene	Tspan15	ENTREZGENE
PANTHER	PTHR19282	UniProtKB/TrEMBL
	TETRASPANIN-15	UniProtKB/TrEMBL
Pfam	Tetraspanin	UniProtKB/TrEMBL
PIRSF	Tetraspanin	UniProtKB/TrEMBL
PRINTS	TMFOUR	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48652	UniProtKB/TrEMBL
UniProt	I3M0K2	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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