Snx25 (sorting nexin 25) - Rat Genome Database

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Gene: Snx25 (sorting nexin 25) Ictidomys tridecemlineatus
Analyze
Symbol: Snx25
Name: sorting nexin 25
RGD ID: 12723433
Description: ENCODES a protein that exhibits type I transforming growth factor beta receptor binding (ortholog); INVOLVED IN negative regulation of transforming growth factor beta receptor signaling pathway (ortholog); receptor catabolic process (ortholog); ASSOCIATED WITH autistic disorder (ortholog); dilated cardiomyopathy (ortholog); genetic disease (ortholog); FOUND IN endosome (inferred); intracellular membrane-bounded organelle (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sorting nexin 25, transcript variant X1; sorting nexin 25, transcript variant X2; sorting nexin 25, transcript variant X3; sorting nexin-25
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494334,020,358 - 34,127,227 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365543,979,441 - 4,087,162 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365543,982,755 - 4,093,143 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Snx25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494334,020,358 - 34,127,227 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365543,979,441 - 4,087,162 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365543,982,755 - 4,093,143 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNX25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384185,204,237 - 185,378,642 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4185,204,237 - 185,370,185 (+)EnsemblGRCh38hg38GRCh38
GRCh374186,125,391 - 186,285,120 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364186,368,278 - 186,522,114 (+)NCBINCBI36Build 36hg18NCBI36
Build 344186,506,432 - 186,660,267NCBI
Celera4183,458,214 - 183,611,271 (+)NCBICelera
Cytogenetic Map4q35.1NCBI
HuRef4181,885,306 - 182,038,630 (+)NCBIHuRef
CHM1_14186,107,800 - 186,261,551 (+)NCBICHM1_1
T2T-CHM13v2.04188,547,948 - 188,721,939 (+)NCBIT2T-CHM13v2.0
Snx25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39846,486,298 - 46,605,535 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl846,486,298 - 46,605,196 (-)EnsemblGRCm39 Ensembl
GRCm38846,033,261 - 46,152,441 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl846,033,261 - 46,152,159 (-)EnsemblGRCm38mm10GRCm38
MGSCv37847,118,615 - 47,209,500 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36847,532,089 - 47,615,519 (-)NCBIMGSCv36mm8
Celera848,716,126 - 48,805,692 (-)NCBICelera
Cytogenetic Map8B1.1NCBI
cM Map826.03NCBI
Snx25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81652,867,102 - 52,971,028 (+)NCBIGRCr8
mRatBN7.21646,134,552 - 46,238,471 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1646,125,804 - 46,238,440 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01649,328,958 - 49,432,415 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1649,350,884 - 49,432,118 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01649,051,539 - 49,159,381 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41649,415,658 - 49,518,663 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11649,415,438 - 49,518,714 (+)NCBI
Celera1644,133,781 - 44,236,984 (+)NCBICelera
Cytogenetic Map16q11NCBI
Snx25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540323,676,002 - 23,787,308 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540323,678,301 - 23,787,256 (-)NCBIChiLan1.0ChiLan1.0
SNX25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23182,919,189 - 183,101,546 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14183,267,470 - 183,449,896 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04177,377,302 - 177,529,601 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14189,631,239 - 189,746,590 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4189,631,239 - 189,746,590 (+)Ensemblpanpan1.1panPan2
SNX25
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11645,269,434 - 45,411,890 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1645,269,412 - 45,403,719 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1645,757,002 - 45,899,584 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01647,485,851 - 47,628,628 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1647,485,862 - 47,621,172 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11645,454,112 - 45,588,797 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01646,066,177 - 46,201,210 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01646,197,403 - 46,340,369 (-)NCBIUU_Cfam_GSD_1.0
SNX25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1546,266,762 - 46,388,324 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11546,306,967 - 46,388,404 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21553,105,358 - 53,186,279 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SNX25
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17131,171,833 - 131,320,054 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7131,207,046 - 131,313,261 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037111,432,323 - 111,584,861 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Snx25
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476916,058,827 - 16,220,716 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000013017   ⟹   ENSSTOP00000011665
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365543,983,275 - 4,087,162 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000037615   ⟹   ENSSTOP00000030731
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365543,979,441 - 4,086,836 (-)Ensembl
RefSeq Acc Id: XM_005329215   ⟹   XP_005329272
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494334,023,045 - 34,127,227 (+)NCBI
SpeTri2.0NW_0049365543,982,765 - 4,086,947 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040294414   ⟹   XP_040150348
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494334,020,358 - 34,127,227 (+)NCBI
RefSeq Acc Id: XM_040294420   ⟹   XP_040150354
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494334,023,043 - 34,127,227 (+)NCBI
RefSeq Acc Id: XM_040294430   ⟹   XP_040150364
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494334,057,302 - 34,127,227 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005329272   ⟸   XM_005329215
- Peptide Label: isoform X3
- UniProtKB: A0A287DB56 (UniProtKB/TrEMBL),   I3MK77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040150348   ⟸   XM_040294414
- Peptide Label: isoform X1
- UniProtKB: I3MK77 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040150354   ⟸   XM_040294420
- Peptide Label: isoform X2
- UniProtKB: I3MK77 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040150364   ⟸   XM_040294430
- Peptide Label: isoform X4
RefSeq Acc Id: ENSSTOP00000011665   ⟸   ENSSTOT00000013017
RefSeq Acc Id: ENSSTOP00000030731   ⟸   ENSSTOT00000037615
Protein Domains
PX   PXA   RGS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000013013 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000013017.3 UniProtKB/TrEMBL
  ENSSTOT00000037615.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.167.10 UniProtKB/TrEMBL
  3.30.1520.10 UniProtKB/TrEMBL
InterPro Phox_assoc UniProtKB/TrEMBL
  PX_dom UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
  RGS_sf UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/TrEMBL
  SNX25_PX UniProtKB/TrEMBL
  Sorting_nexin_C UniProtKB/TrEMBL
NCBI Gene Snx25 ENTREZGENE
PANTHER PTHR22775:SF29 UniProtKB/TrEMBL
  SORTING NEXIN UniProtKB/TrEMBL
Pfam Nexin_C UniProtKB/TrEMBL
  PF00787 UniProtKB/TrEMBL
  PXA UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
PROSITE PS50195 UniProtKB/TrEMBL
  PXA UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
SMART PXA UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
  SM00312 UniProtKB/TrEMBL
Superfamily-SCOP SSF48097 UniProtKB/TrEMBL
  SSF64268 UniProtKB/TrEMBL
UniProt A0A287DB56 ENTREZGENE, UniProtKB/TrEMBL
  I3MK77 ENTREZGENE, UniProtKB/TrEMBL