Tmprss7 (transmembrane serine protease 7)

Gene: Tmprss7 (transmembrane serine protease 7) Ictidomys tridecemlineatus

Analyze

Symbol:

Tmprss7

Name:

transmembrane serine protease 7

RGD ID:

12722564

Description:

ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH genetic disease (ortholog); substance-related disorder (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

transmembrane protease serine 7; transmembrane protease, serine 7

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	137,707,425 - 137,741,433 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936834	842,670 - 876,300 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936834	844,560 - 876,722 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

substance-related disorder (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

proteolysis (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IEA)

Molecular Function

hydrolase activity (IEA)

peptidase activity (IEA)

protein binding (ISO)

serine-type endopeptidase activity (IEA)

serine-type peptidase activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Tmprss7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	137,707,425 - 137,741,433 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936834	842,670 - 876,300 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936834	844,560 - 876,722 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMPRSS7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	112,034,736 - 112,081,269 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	112,034,736 - 112,081,269 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	111,753,583 - 111,800,116 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	113,241,155 - 113,282,806 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	3	110,157,540 - 110,199,202 (+)	NCBI		Celera
Cytogenetic Map	3	q13.2	NCBI
HuRef	3	109,133,795 - 109,175,302 (+)	NCBI		HuRef
CHM1_1	3	111,722,491 - 111,764,152 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	114,755,830 - 114,802,379 (+)	NCBI		T2T-CHM13v2.0

Tmprss7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	45,476,672 - 45,521,822 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	45,476,678 - 45,514,021 (-)	Ensembl		GRCm39 Ensembl
GRCm38	16	45,656,309 - 45,698,553 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	45,656,315 - 45,693,658 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	45,656,430 - 45,685,489 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	45,701,712 - 45,730,853 (-)	NCBI		MGSCv36	mm8
MGSCv36	16	45,575,649 - 45,604,708 (-)	NCBI		MGSCv36	mm8
Celera	16	46,031,572 - 46,061,693 (-)	NCBI		Celera
Cytogenetic Map	16	B5	NCBI
cM Map	16	29.84	NCBI

Tmprss7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	68,583,710 - 68,629,200 (+)	NCBI		GRCr8
mRatBN7.2	11	55,127,992 - 55,166,597 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	55,128,998 - 55,164,882 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	63,904,071 - 63,939,917 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	56,565,948 - 56,601,792 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	55,671,855 - 55,707,516 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	60,102,125 - 60,138,065 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	60,102,121 - 60,138,059 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	64,202,921 - 64,238,347 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	56,617,542 - 56,653,695 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	56,675,130 - 56,711,184 (+)	NCBI
Celera	11	54,653,229 - 54,688,824 (+)	NCBI		Celera
Cytogenetic Map	11	q21	NCBI

Tmprss7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955427	12,447,058 - 12,483,454 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955427	12,447,058 - 12,483,454 (+)	NCBI	ChiLan1.0	ChiLan1.0

TMPRSS7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	110,037,618 - 110,081,253 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	110,042,398 - 110,086,033 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	109,179,159 - 109,225,631 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	116,107,948 - 116,149,499 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	116,103,174 - 116,149,315 (+)	Ensembl	panpan1.1		panPan2

TMPRSS7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	33	16,669,008 - 16,704,774 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	33	16,667,181 - 16,704,531 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	33	16,770,726 - 16,806,463 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	33	16,907,168 - 16,942,916 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	33	16,905,320 - 16,942,672 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	33	16,717,263 - 16,752,687 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	33	16,762,866 - 16,798,313 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	33	17,307,691 - 17,343,180 (+)	NCBI		UU_Cfam_GSD_1.0

TMPRSS7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	147,686,913 - 147,728,803 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	147,686,900 - 147,726,169 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	157,327,228 - 157,369,674 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMPRSS7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	68,710,879 - 68,759,766 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	68,710,932 - 68,758,553 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	97,725,706 - 97,763,578 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmprss7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624731	36,491,205 - 36,530,391 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624731	36,491,133 - 36,528,346 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021720651	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040270581	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000028933 ⟹ ENSSTOP00000020607

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936834	842,670 - 876,300 (+)	Ensembl

RefSeq Acc Id:

XM_040270581 ⟹ XP_040126515

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	137,707,425 - 137,741,433 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_040126515	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000020607.2
GenBank Protein	KAG3271481	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_040126515 ⟸ XM_040270581
- UniProtKB:	I3N8B1 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSSTOP00000020607 ⟸ ENSSTOT00000028933

Protein Domains

CUB Peptidase S1 SEA

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000022989	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000028933.2	UniProtKB/TrEMBL
Gene3D-CATH	2.40.10.10	UniProtKB/TrEMBL
	2.60.120.290	UniProtKB/TrEMBL
	3.30.70.960	UniProtKB/TrEMBL
	4.10.400.10	UniProtKB/TrEMBL
InterPro	CUB_dom	UniProtKB/TrEMBL
	LDL_receptor-like_sf	UniProtKB/TrEMBL
	LDrepeatLR_classA_rpt	UniProtKB/TrEMBL
	Peptidase_S1_PA	UniProtKB/TrEMBL
	Peptidase_S1_PA_chymotrypsin	UniProtKB/TrEMBL
	Peptidase_S1A	UniProtKB/TrEMBL
	SEA_dom	UniProtKB/TrEMBL
	SEA_dom_sf	UniProtKB/TrEMBL
	Sperma_CUB_dom_sf	UniProtKB/TrEMBL
	Trypsin_dom	UniProtKB/TrEMBL
	TRYPSIN_HIS	UniProtKB/TrEMBL
	TRYPSIN_SER	UniProtKB/TrEMBL
NCBI Gene	Tmprss7	ENTREZGENE
PANTHER	ACROSIN-RELATED	UniProtKB/TrEMBL
	SERINE PROTEASE 56	UniProtKB/TrEMBL
Pfam	CUB	UniProtKB/TrEMBL
	SEA	UniProtKB/TrEMBL
	Trypsin	UniProtKB/TrEMBL
PRINTS	CHYMOTRYPSIN	UniProtKB/TrEMBL
PROSITE	CUB	UniProtKB/TrEMBL
	SEA	UniProtKB/TrEMBL
	TRYPSIN_DOM	UniProtKB/TrEMBL
	TRYPSIN_HIS	UniProtKB/TrEMBL
	TRYPSIN_SER	UniProtKB/TrEMBL
SMART	CUB	UniProtKB/TrEMBL
	Tryp_SPc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49854	UniProtKB/TrEMBL
	SSF50494	UniProtKB/TrEMBL
	SSF82671	UniProtKB/TrEMBL
UniProt	I3N8B1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-01-23	Tmprss7	transmembrane serine protease 7		transmembrane protease, serine 7	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD