Otx2 (orthodenticle homeobox 2) - Rat Genome Database

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Gene: Otx2 (orthodenticle homeobox 2) Ictidomys tridecemlineatus
Analyze
Symbol: Otx2
Name: orthodenticle homeobox 2
RGD ID: 12720362
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN anatomical structure development (ortholog); animal organ morphogenesis (ortholog); anterior/posterior pattern specification (ortholog); ASSOCIATED WITH Anophthalmia (ortholog); Combined Pituitary Hormone Deficiency, 6 (ortholog); fundus dystrophy (ortholog); FOUND IN cytoplasm (ortholog); growth cone (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: homeobox protein OTX2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864072,742,666 - 72,758,575 (+)NCBI
SpeTri2.0NW_0049364951,433,124 - 1,449,409 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

Genomics

Comparative Map Data
Otx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864072,742,666 - 72,758,575 (+)NCBI
SpeTri2.0NW_0049364951,433,124 - 1,449,409 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OTX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1456,799,905 - 56,816,693 (-)EnsemblGRCh38hg38GRCh38
GRCh381456,799,905 - 56,810,479 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371457,266,623 - 57,277,197 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361456,337,178 - 56,346,937 (-)NCBINCBI36hg18NCBI36
Build 341456,337,179 - 56,342,098NCBI
Celera1437,316,938 - 37,326,697 (-)NCBI
Cytogenetic Map14q22.3NCBI
HuRef1437,431,939 - 37,441,708 (-)NCBIHuRef
CHM1_11457,206,163 - 57,215,915 (-)NCBICHM1_1
Otx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391448,894,238 - 48,905,101 (-)NCBIGRCm39mm39
GRCm39 Ensembl1448,895,134 - 48,911,276 (-)Ensembl
GRCm381448,656,781 - 48,667,644 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1448,657,677 - 48,673,819 (-)EnsemblGRCm38mm10GRCm38
MGSCv371449,277,846 - 49,282,547 (-)NCBIGRCm37mm9NCBIm37
MGSCv361447,579,630 - 47,587,057 (-)NCBImm8
Celera1444,858,278 - 44,862,991 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1425.36NCBI
Otx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21521,942,233 - 21,953,034 (-)NCBI
Rnor_6.0 Ensembl1525,502,019 - 25,505,691 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1525,517,721 - 25,521,393 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01525,500,037 - 25,511,619 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01529,425,136 - 29,435,678 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41524,622,851 - 24,632,435 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11524,638,550 - 24,643,418 (-)NCBI
Celera1522,321,144 - 22,330,728 (-)NCBICelera
Cytogenetic Map15p14NCBI
Otx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546610,755,012 - 10,765,095 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546610,755,143 - 10,764,957 (-)NCBIChiLan1.0ChiLan1.0
OTX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11455,641,349 - 55,651,012 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1455,641,349 - 55,651,012 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01437,370,926 - 37,381,610 (-)NCBIMhudiblu_PPA_v0panPan3
OTX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1832,435,169 - 32,445,093 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl832,435,863 - 32,445,446 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha832,203,297 - 32,213,040 (-)NCBI
ROS_Cfam_1.0832,685,680 - 32,695,437 (-)NCBI
UMICH_Zoey_3.1832,288,616 - 32,298,366 (-)NCBI
UNSW_CanFamBas_1.0832,364,566 - 32,374,316 (-)NCBI
UU_Cfam_GSD_1.0832,740,360 - 32,750,115 (-)NCBI
OTX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1186,028,575 - 186,038,229 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11186,028,575 - 186,039,026 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21206,642,523 - 206,650,665 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OTX2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12433,975,043 - 33,984,816 (-)NCBI
Otx2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248841,830,645 - 1,840,213 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005322733   ⟹   XP_005322790
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864072,748,859 - 72,758,575 (+)NCBI
SpeTri2.0NW_0049364951,433,124 - 1,442,862 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005322736   ⟹   XP_005322793
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864072,748,859 - 72,758,575 (+)NCBI
SpeTri2.0NW_0049364951,433,124 - 1,442,857 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013357488   ⟹   XP_013212942
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864072,751,535 - 72,758,575 (+)NCBI
SpeTri2.0NW_0049364951,433,124 - 1,440,175 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021724748   ⟹   XP_021580423
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864072,748,859 - 72,758,575 (+)NCBI
SpeTri2.0NW_0049364951,433,124 - 1,442,862 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021724749   ⟹   XP_021580424
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864072,742,666 - 72,758,575 (+)NCBI
SpeTri2.0NW_0049364951,433,124 - 1,449,409 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021724750   ⟹   XP_021580425
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864072,751,239 - 72,758,575 (+)NCBI
SpeTri2.0NW_0049364951,433,124 - 1,440,503 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021724751   ⟹   XP_021580426
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049364951,433,124 - 1,440,938 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021724752   ⟹   XP_021580427
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864072,749,493 - 72,758,575 (+)NCBI
SpeTri2.0NW_0049364951,433,124 - 1,440,938 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040274665   ⟹   XP_040130599
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864072,747,948 - 72,758,575 (+)NCBI
RefSeq Acc Id: XM_040274666   ⟹   XP_040130600
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864072,751,240 - 72,758,575 (+)NCBI
RefSeq Acc Id: XM_040274667   ⟹   XP_040130601
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864072,742,666 - 72,758,575 (+)NCBI
RefSeq Acc Id: XM_040274668   ⟹   XP_040130602
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864072,749,493 - 72,758,575 (+)NCBI
RefSeq Acc Id: XM_040274669   ⟹   XP_040130603
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864072,752,870 - 72,758,575 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_005322793   ⟸   XM_005322736
- Peptide Label: isoform X2
- UniProtKB: I3N222 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005322790   ⟸   XM_005322733
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013212942   ⟸   XM_013357488
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021580424   ⟸   XM_021724749
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021580423   ⟸   XM_021724748
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021580427   ⟸   XM_021724752
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021580426   ⟸   XM_021724751
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021580425   ⟸   XM_021724750
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_040130601   ⟸   XM_040274667
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040130599   ⟸   XM_040274665
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040130602   ⟸   XM_040274668
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040130600   ⟸   XM_040274666
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040130603   ⟸   XM_040274669
- Peptide Label: isoform X2
Protein Domains
Homeobox


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000028544 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000018418 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000025664 UniProtKB/TrEMBL
InterPro Homeobox-like UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Otx2_TF UniProtKB/TrEMBL
  Otx_TF UniProtKB/TrEMBL
  Otx_TF_C UniProtKB/TrEMBL
NCBI Gene Otx2 ENTREZGENE
Pfam Homeobox UniProtKB/TrEMBL
  TF_Otx UniProtKB/TrEMBL
PRINTS OTX2HOMEOBOX UniProtKB/TrEMBL
  OTXHOMEOBOX UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt I3N222 ENTREZGENE, UniProtKB/TrEMBL