Znf181 (zinc finger protein 181) - Rat Genome Database

Name: Znf181
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Znf181 (zinc finger protein 181) Ictidomys tridecemlineatus

Analyze

Symbol:

Znf181

Name:

zinc finger protein 181

RGD ID:

12719887

Description:

ENCODES a protein that exhibits DNA-binding transcription factor activity (inferred); DNA-binding transcription repressor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (inferred); regulation of DNA-templated transcription (inferred); regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH genetic disease (ortholog); hereditary spastic paraplegia 75 (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC106145055; zinc finger protein 181-like

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	10,245,261 - 10,253,805 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936570	1,392,578 - 1,400,727 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

hereditary spastic paraplegia 75 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of transcription by RNA polymerase II (IEA)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IEA)

Molecular Function

DNA-binding transcription factor activity (IEA)

DNA-binding transcription repressor activity, RNA polymerase II-specific (IEA)

metal ion binding (IEA)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Znf181
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	10,245,261 - 10,253,805 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936570	1,392,578 - 1,400,727 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZNF181
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	34,734,243 - 34,745,378 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	34,734,155 - 34,745,378 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	35,225,148 - 35,236,283 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	39,916,933 - 39,925,613 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	31,937,872 - 31,946,166 (+)	NCBI		Celera
Cytogenetic Map	19	q13.11	NCBI
HuRef	19	31,732,223 - 31,740,518 (+)	NCBI		HuRef
CHM1_1	19	35,227,149 - 35,235,443 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	37,277,885 - 37,289,960 (+)	NCBI		T2T-CHM13v2.0

Znf181
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955468	4,196,213 - 4,214,531 (+)	NCBI	ChiLan1.0	ChiLan1.0

LOC484590
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	117,725,051 - 117,734,847 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	117,125,064 - 117,134,882 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	118,321,748 - 118,331,589 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	1	117,884,182 - 117,894,017 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	117,510,220 - 117,520,230 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	118,566,952 - 118,576,804 (-)	NCBI		UU_Cfam_GSD_1.0

ZNF181
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	6	44,345,408 - 44,357,775 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	39,692,921 - 39,785,673 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZNF181
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	29,648,089 - 29,691,258 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666073	7,450,243 - 7,460,008 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013360919	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013360920	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010004409	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_013360919 ⟹ XP_013216373

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409349	10,245,261 - 10,253,805 (+)	NCBI
SpeTri2.0	NW_004936570	1,392,578 - 1,400,721 (-)	NCBI

Sequence:

show sequence

AGGTCGAGGGGTCTGGACTGGGGTCTGGACTGCGGCGTCCGCTCTGGGCTCGTCCCGCGGCGCT
GCCCGGCCTGGCTCCGCTCTTCTGGAATCGGTTGGGAATCTGTGCGGACTATTCCCGGGAGGCG
GCGGCCGTTGCCAGCTCTCCGGCGTCCGAAGCGTCAGGAACACTACCCATCCGTAAGCCACAAA
GCTAGAAAAGGAACGGTGTGGACTATTGGAAATTGTAATGACTCAGGTGACATTTAGTGATGTG
GCTATAGACTTCTCTCATGAAGAGTGGGCATGGTTAGATTCTGCGCAGAAGGATTTATACAAGG
ATGTGATGGTGCAGAACTATGAAAATCTGGTCTCTCTAGCAGGTCTTTCCATAACTAAGCCATA
TGTGATCACTTTATTGGAGGATGGAAAAGAACCCTGGATGGTGGAGAAAACACTGTCAAAAGAT
TGGGAATCAAGATGGGAAAACAAGGAATTATCAACAAAGGATATTTATGATGAAGATTCACCCC
AAACAGAAAAAATAGAAAAAAACATAAGGCGGCATTGTGAATTTTCATATTTTAATAAGAACGG
AAAGTATAAAGGGAAGTTGGAGGGGAAGGATGGACATCAGGTAGAACATTGCAGACCAATGACC
CTCACCTTTAGTGAGAGCCCCTCTGGGGAAAGTGTTGACAAATACAGTACGTCATTTAGAAGCA
TCTTCCATGTAAAGCCTACTCTTTCTGAACCACAGATAATTTCTGCTGAATGGACATTGCATAA
ATATGATATGTTAAAGAAGAGTTTACCAATAGGGTCAGTTATAGAAAACGAGAAAATCAGTGGC
AGAAAGAAAGTTTTGAGTTCTAATGAAAGTGTGGCAACTTTTAGCAAAAGCAAATCTCTTACCC
TTCATCAGACTTTTAATAGAGAGAAGATCTTTACATGTAGTGAATGTGGGAAAGCCTTTGGTAA
ACAATCAATCCTTAATCGCCATTGGAGAATTCATACAGGAGAGAAACCTTATCATTGTCGTGAA
TGTGGGAAGACTTTTAGCCATGGCTCATCCCTTACTCGACATCAAATAAGCCATAGTGGAGAGA
AGCCTTACAAATGTGCTGAATGTGGAAAGGCCTTTAGTCATGTCTCTTCTCTTACTAATCATCA
AAGCACTCACACTGGAGAGAAACCATATGAATGTACGAACTGTGGAAAGTCTTTTAGTCGTGTT
TCACATCTCATTGAACATCTGAGGATTCATACTCAAGAAAAACTTTATGAGTGCCAAATATGTG
GGAAGGCCTTCATTCATAGGTCATCTCTTATCCACCATCAGAAAATACATACTGGAGAGAAACC
TTATGAATGTAGTGAATGTGGGAAAGCTTTTTGCTGTAGCTCACACCTTACTCGACATCAAAGA
ATTCACACTATCGAGAAACAATATGAATGTAACAAATGTCTGAAAGTCTTTAGTAGCCTCTCAT
TTCTTATTCAACATCAGAGTATTCATTCTGAAGAAAAACCCTTTGAATGTCAGAAATGTAGGAA
ATCTTTCAGCCAGCCTGAATCACTGAATATGCATTTGAGAAATCACATTAGATTGAAACCTTAT
GAATGCAGTATATGTGGGAAAGCCTTCAGTCACAGGTCATCCCTGCTTCAACATCACAGAATTC
ATACTGGAGAAAGACCTTATGAGTGTATTAAATGTGGGAAGACCTTCAGCTGTAGTTCAAACCT
TACTGTACATCAGAGAATTCATACTGGAGAAAAGCCATATAAATGTGATGAATGTGGAAAAGCT
TTTAGTAAAGGTTCAAATCTTACTGCCCATCAGAAAACACATAATGGACAAAAACCCAGTAATG
CAGTAAATATGGAAAGGTCTTTAGACTGTATAAATCAGTATGCATATGAGAAATCATACAAGAG
AGAAACTATATGAAGCATCATTTTTTATAATAAATTTCAGCCACAAATCCTAATTCAATATCAA
AATTTTTGAGAACAGTCTTACAAGTGTAGTGTTTATGGGAAGACCTTTAGTGTTTATGATGAAA
CCTTTATTGTCTATCAGAGTTCATGCTATAGAAAACCATAAGAGGATAACAAATGTGGGAAGGC
CTTTGTCAGTATTAATCCCTTAGTTGACATAAGTAAATACAGACAAGAAAAAAAAAACTA

hide sequence

RefSeq Acc Id:

XM_013360920 ⟹ XP_013216374

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409349	10,245,261 - 10,253,805 (+)	NCBI
SpeTri2.0	NW_004936570	1,392,578 - 1,400,727 (-)	NCBI

Sequence:

show sequence

TTCCGGAGGTCGAGGGGTCTGGACTGGGGTCTGGACTGCGGCGTCCGCTCTGGGCTCGTCCCGC
GGCGCTGCCCGGCCTGGCTCCGCTCTTCTGGAATCGGTTGGGAATCTGTGCGGACTATTCCCGG
GAGGCGGCGGCCGTTGCCAGCTCTCCGGCGTCCGAAGCGTCAGGAACACTACCCATCCGTAAGC
CACAAAGCTAGAAAAGGAACGGTGTGGACTATTGGAAATTGTAATGACTCAGGTGACATTTAGT
GATGTGGCTATAGACTTCTCTCATGAAGAGTGGGCATGGTTAGATTCTGCGCAGAAGGATTTAT
ACAAGGATGTGATGGTGCAGAACTATGAAAATCTGGTCTCTCTAGGTCTTTCCATAACTAAGCC
ATATGTGATCACTTTATTGGAGGATGGAAAAGAACCCTGGATGGTGGAGAAAACACTGTCAAAA
GATTGGGAATCAAGATGGGAAAACAAGGAATTATCAACAAAGGATATTTATGATGAAGATTCAC
CCCAAACAGAAAAAATAGAAAAAAACATAAGGCGGCATTGTGAATTTTCATATTTTAATAAGAA
CGGAAAGTATAAAGGGAAGTTGGAGGGGAAGGATGGACATCAGGTAGAACATTGCAGACCAATG
ACCCTCACCTTTAGTGAGAGCCCCTCTGGGGAAAGTGTTGACAAATACAGTACGTCATTTAGAA
GCATCTTCCATGTAAAGCCTACTCTTTCTGAACCACAGATAATTTCTGCTGAATGGACATTGCA
TAAATATGATATGTTAAAGAAGAGTTTACCAATAGGGTCAGTTATAGAAAACGAGAAAATCAGT
GGCAGAAAGAAAGTTTTGAGTTCTAATGAAAGTGTGGCAACTTTTAGCAAAAGCAAATCTCTTA
CCCTTCATCAGACTTTTAATAGAGAGAAGATCTTTACATGTAGTGAATGTGGGAAAGCCTTTGG
TAAACAATCAATCCTTAATCGCCATTGGAGAATTCATACAGGAGAGAAACCTTATCATTGTCGT
GAATGTGGGAAGACTTTTAGCCATGGCTCATCCCTTACTCGACATCAAATAAGCCATAGTGGAG
AGAAGCCTTACAAATGTGCTGAATGTGGAAAGGCCTTTAGTCATGTCTCTTCTCTTACTAATCA
TCAAAGCACTCACACTGGAGAGAAACCATATGAATGTACGAACTGTGGAAAGTCTTTTAGTCGT
GTTTCACATCTCATTGAACATCTGAGGATTCATACTCAAGAAAAACTTTATGAGTGCCAAATAT
GTGGGAAGGCCTTCATTCATAGGTCATCTCTTATCCACCATCAGAAAATACATACTGGAGAGAA
ACCTTATGAATGTAGTGAATGTGGGAAAGCTTTTTGCTGTAGCTCACACCTTACTCGACATCAA
AGAATTCACACTATCGAGAAACAATATGAATGTAACAAATGTCTGAAAGTCTTTAGTAGCCTCT
CATTTCTTATTCAACATCAGAGTATTCATTCTGAAGAAAAACCCTTTGAATGTCAGAAATGTAG
GAAATCTTTCAGCCAGCCTGAATCACTGAATATGCATTTGAGAAATCACATTAGATTGAAACCT
TATGAATGCAGTATATGTGGGAAAGCCTTCAGTCACAGGTCATCCCTGCTTCAACATCACAGAA
TTCATACTGGAGAAAGACCTTATGAGTGTATTAAATGTGGGAAGACCTTCAGCTGTAGTTCAAA
CCTTACTGTACATCAGAGAATTCATACTGGAGAAAAGCCATATAAATGTGATGAATGTGGAAAA
GCTTTTAGTAAAGGTTCAAATCTTACTGCCCATCAGAAAACACATAATGGACAAAAACCCAGTA
ATGCAGTAAATATGGAAAGGTCTTTAGACTGTATAAATCAGTATGCATATGAGAAATCATACAA
GAGAGAAACTATATGAAGCATCATTTTTTATAATAAATTTCAGCCACAAATCCTAATTCAATAT
CAAAATTTTTGAGAACAGTCTTACAAGTGTAGTGTTTATGGGAAGACCTTTAGTGTTTATGATG
AAACCTTTATTGTCTATCAGAGTTCATGCTATAGAAAACCATAAGAGGATAACAAATGTGGGAA
GGCCTTTGTCAGTATTAATCCCTTAGTTGACATAAGTAAATACAGACAAGAAAAAAAAAACTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013216373	(Get FASTA)	NCBI Sequence Viewer
	XP_013216374	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000003100.2
	ENSSTOP00000028508.1
GenBank Protein	KAG3255813	(Get FASTA)	NCBI Sequence Viewer
	KAG3255814	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_013216374 ⟸ XM_013360920

- Peptide Label:

isoform X2

- Sequence:

show sequence

MTQVTFSDVAIDFSHEEWAWLDSAQKDLYKDVMVQNYENLVSLGLSITKPYVITLLEDGKEPWM
VEKTLSKDWESRWENKELSTKDIYDEDSPQTEKIEKNIRRHCEFSYFNKNGKYKGKLEGKDGHQ
VEHCRPMTLTFSESPSGESVDKYSTSFRSIFHVKPTLSEPQIISAEWTLHKYDMLKKSLPIGSV
IENEKISGRKKVLSSNESVATFSKSKSLTLHQTFNREKIFTCSECGKAFGKQSILNRHWRIHTG
EKPYHCRECGKTFSHGSSLTRHQISHSGEKPYKCAECGKAFSHVSSLTNHQSTHTGEKPYECTN
CGKSFSRVSHLIEHLRIHTQEKLYECQICGKAFIHRSSLIHHQKIHTGEKPYECSECGKAFCCS
SHLTRHQRIHTIEKQYECNKCLKVFSSLSFLIQHQSIHSEEKPFECQKCRKSFSQPESLNMHLR
NHIRLKPYECSICGKAFSHRSSLLQHHRIHTGERPYECIKCGKTFSCSSNLTVHQRIHTGEKPY
KCDECGKAFSKGSNLTAHQKTHNGQKPSNAVNMERSLDCINQYAYEKSYKRETI

hide sequence

RefSeq Acc Id:

XP_013216373 ⟸ XM_013360919

- Peptide Label:

isoform X1

- Sequence:

show sequence

MTQVTFSDVAIDFSHEEWAWLDSAQKDLYKDVMVQNYENLVSLAGLSITKPYVITLLEDGKEPW
MVEKTLSKDWESRWENKELSTKDIYDEDSPQTEKIEKNIRRHCEFSYFNKNGKYKGKLEGKDGH
QVEHCRPMTLTFSESPSGESVDKYSTSFRSIFHVKPTLSEPQIISAEWTLHKYDMLKKSLPIGS
VIENEKISGRKKVLSSNESVATFSKSKSLTLHQTFNREKIFTCSECGKAFGKQSILNRHWRIHT
GEKPYHCRECGKTFSHGSSLTRHQISHSGEKPYKCAECGKAFSHVSSLTNHQSTHTGEKPYECT
NCGKSFSRVSHLIEHLRIHTQEKLYECQICGKAFIHRSSLIHHQKIHTGEKPYECSECGKAFCC
SSHLTRHQRIHTIEKQYECNKCLKVFSSLSFLIQHQSIHSEEKPFECQKCRKSFSQPESLNMHL
RNHIRLKPYECSICGKAFSHRSSLLQHHRIHTGERPYECIKCGKTFSCSSNLTVHQRIHTGEKP
YKCDECGKAFSKGSNLTAHQKTHNGQKPSNAVNMERSLDCINQYAYEKSYKRETI

hide sequence

Protein Domains

C2H2-type KRAB

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000003480	UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000003465.2	UniProtKB/TrEMBL
	ENSSTOT00000043209.1	UniProtKB/TrEMBL
Gene3D-CATH	6.10.140.140	UniProtKB/TrEMBL
	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	KRAB	UniProtKB/TrEMBL
	KRAB_dom_sf	UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/TrEMBL
	Znf_C2H2_type	UniProtKB/TrEMBL
NCBI Gene	LOC106145055	ENTREZGENE
PANTHER	B-CELL CLL_LYMPHOMA 6 MEMBER B PROTEIN	UniProtKB/TrEMBL
	ZINC FINGER PROTEIN	UniProtKB/TrEMBL
	ZINC FINGER PROTEIN	UniProtKB/TrEMBL
	ZINC FINGER PROTEIN 835	UniProtKB/TrEMBL
Pfam	KRAB	UniProtKB/TrEMBL
	zf-C2H2	UniProtKB/TrEMBL
PROSITE	KRAB	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/TrEMBL
SMART	KRAB	UniProtKB/TrEMBL
	ZnF_C2H2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF109640	UniProtKB/TrEMBL
	SSF57667	UniProtKB/TrEMBL
UniProt	A0A287D4M8_ICTTR	UniProtKB/TrEMBL
	I3M2B8_ICTTR	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-07-13	Znf181	zinc finger protein 181	LOC106145055	zinc finger protein 181-like	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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