Hdac8 (histone deacetylase 8) - Rat Genome Database

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Gene: Hdac8 (histone deacetylase 8) Ictidomys tridecemlineatus
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Symbol: Hdac8
Name: histone deacetylase 8
RGD ID: 12719654
Description: ENCODES a protein that exhibits chromatin binding (ortholog); deacetylase activity (ortholog); Hsp70 protein binding (ortholog); INVOLVED IN cellular response to forskolin (ortholog); cellular response to trichostatin A (ortholog); negative regulation of gene expression (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH amphetamine abuse (ortholog); atrial heart septal defect (ortholog); autistic disorder (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: histone deacetylase 8, transcript variant X1; histone deacetylase 8, transcript variant X2; histone deacetylase 8, transcript variant X3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X45,327,793 - 45,554,498 (+)NCBI
SpeTri2.0NW_0049367621,425,337 - 1,652,058 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Hdac8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X45,327,793 - 45,554,498 (+)NCBI
SpeTri2.0NW_0049367621,425,337 - 1,652,058 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HDAC8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX72,329,516 - 72,573,101 (-)EnsemblGRCh38hg38GRCh38
GRCh38X72,329,516 - 72,573,099 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X71,549,366 - 71,792,693 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X71,466,091 - 71,709,378 (-)NCBINCBI36hg18NCBI36
Build 34X71,332,387 - 71,575,674NCBI
CeleraX71,892,584 - 72,136,175 (-)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX65,303,729 - 65,547,461 (-)NCBIHuRef
CHM1_1X71,442,370 - 71,685,931 (-)NCBICHM1_1
Hdac8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X101,328,244 - 101,549,005 (-)NCBIGRCm39mm39
GRCm39 EnsemblX101,328,245 - 101,548,965 (-)Ensembl
GRCm38X102,284,638 - 102,505,381 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX102,284,639 - 102,505,359 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X99,479,979 - 99,700,487 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X98,487,359 - 98,707,867 (-)NCBImm8
CeleraX89,195,856 - 89,416,063 (-)NCBICelera
Cytogenetic MapXDNCBI
Hdac8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X67,385,288 - 67,593,014 (-)NCBI
Rnor_6.0 EnsemblX72,163,777 - 72,370,044 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X72,163,777 - 72,370,058 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X73,694,610 - 73,698,948 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0X73,566,613 - 73,589,000 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X90,336,001 - 90,544,511 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX67,738,891 - 67,946,303 (-)NCBICelera
Cytogenetic MapXq22NCBI
Hdac8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495547511,748,502 - 12,012,884 (-)NCBIChiLan1.0ChiLan1.0
HDAC8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X71,649,178 - 71,894,896 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0X61,565,790 - 61,811,588 (-)NCBIMhudiblu_PPA_v0panPan3
HDAC8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X56,357,205 - 56,574,443 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX56,357,177 - 56,574,401 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX47,183,095 - 47,400,619 (-)NCBI
ROS_Cfam_1.0X57,411,265 - 57,628,877 (-)NCBI
UMICH_Zoey_3.1X55,325,722 - 55,544,604 (-)NCBI
UNSW_CanFamBas_1.0X56,723,145 - 56,940,470 (-)NCBI
UU_Cfam_GSD_1.0X56,571,889 - 56,789,465 (-)NCBI
HDAC8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X58,210,182 - 58,450,681 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
HDAC8
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X62,154,374 - 62,393,149 (-)NCBI
Vero_WHO_p1.0NW_0236660654,003,868 - 4,261,439 (-)NCBI
Hdac8
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249032,620,571 - 2,852,247 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005339995   ⟹   XP_005340052
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X45,327,795 - 45,554,498 (+)NCBI
SpeTri2.0NW_0049367621,425,337 - 1,652,058 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013365046   ⟹   XP_013220500
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X45,327,795 - 45,416,569 (+)NCBI
SpeTri2.0NW_0049367621,563,174 - 1,652,058 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021719923   ⟹   XP_021575598
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X45,327,793 - 45,508,344 (+)NCBI
SpeTri2.0NW_0049367621,471,471 - 1,652,058 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040281892   ⟹   XP_040137826
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X45,327,793 - 45,554,498 (+)NCBI
RefSeq Acc Id: XM_040281895   ⟹   XP_040137829
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X45,327,793 - 45,554,498 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_005340052   ⟸   XM_005339995
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013220500   ⟸   XM_013365046
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_021575598   ⟸   XM_021719923
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_040137826   ⟸   XM_040281892
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040137829   ⟸   XM_040281895
- Peptide Label: isoform X4
Protein Domains
Hist_deacetyl


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000008440 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000007569 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000008444 UniProtKB/TrEMBL
Gene3D-CATH 3.40.800.20 UniProtKB/TrEMBL
InterPro His_deacetylse UniProtKB/TrEMBL
  His_deacetylse_1 UniProtKB/TrEMBL
  His_deacetylse_dom UniProtKB/TrEMBL
  His_deacetylse_dom_sf UniProtKB/TrEMBL
  Ureohydrolase_dom_sf UniProtKB/TrEMBL
NCBI Gene Hdac8 ENTREZGENE
Pfam Hist_deacetyl UniProtKB/TrEMBL
PIRSF His_deacetylse_1 UniProtKB/TrEMBL
PRINTS HDASUPER UniProtKB/TrEMBL
  HISDACETLASE UniProtKB/TrEMBL
Superfamily-SCOP SSF52768 UniProtKB/TrEMBL
UniProt I3MBM8_ICTTR UniProtKB/TrEMBL