Tanc2 (tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2) - Rat Genome Database

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Gene: Tanc2 (tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2) Ictidomys tridecemlineatus
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Symbol: Tanc2
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
RGD ID: 12719625
Description: ENCODES a protein that exhibits structural constituent of postsynaptic density (ortholog); INVOLVED IN dense core granule cytoskeletal transport (ortholog); in utero embryonic development (ortholog); regulation of dendritic spine development (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); epilepsy (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density (ortholog); postsynaptic density, intracellular component (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, transcript variant X1; tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, transcript variant X2; tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, transcript variant X3; tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, transcript variant X4; tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, transcript variant X5; tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, transcript variant X6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560215,074,440 - 15,491,870 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365413,744,687 - 4,115,007 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365413,702,743 - 4,115,009 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tanc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560215,074,440 - 15,491,870 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365413,744,687 - 4,115,007 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365413,702,743 - 4,115,009 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TANC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381762,966,235 - 63,427,703 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1762,966,235 - 63,427,703 (+)EnsemblGRCh38hg38GRCh38
GRCh371761,043,596 - 61,505,064 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361758,440,630 - 58,858,799 (+)NCBINCBI36Build 36hg18NCBI36
Celera1755,475,137 - 55,893,299 (+)NCBICelera
Cytogenetic Map17q23.2-q23.3NCBI
HuRef1756,455,117 - 56,873,425 (+)NCBIHuRef
CHM1_11761,151,133 - 61,569,236 (+)NCBICHM1_1
T2T-CHM13v2.01763,836,303 - 64,297,911 (+)NCBIT2T-CHM13v2.0
Tanc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911105,480,458 - 105,820,130 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11105,480,812 - 105,820,130 (+)EnsemblGRCm39 Ensembl
GRCm3811105,589,460 - 105,929,304 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11105,589,986 - 105,929,304 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711105,451,300 - 105,790,618 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611105,406,081 - 105,745,394 (+)NCBIMGSCv36mm8
Celera11117,319,535 - 117,661,003 (+)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1168.73NCBI
Tanc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81091,052,860 - 91,373,291 (+)NCBIGRCr8
mRatBN7.21090,553,124 - 90,873,477 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1090,553,002 - 90,868,756 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1095,601,396 - 95,915,458 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01095,064,563 - 95,378,631 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01090,482,967 - 90,797,525 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01093,811,350 - 94,132,418 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1093,811,350 - 94,127,697 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01093,567,079 - 93,880,565 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41094,992,107 - 95,319,058 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11095,005,414 - 95,332,662 (+)NCBI
Celera1089,232,884 - 89,546,990 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
Tanc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554788,376,487 - 8,757,136 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554788,370,813 - 8,757,132 (-)NCBIChiLan1.0ChiLan1.0
TANC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21979,129,141 - 79,601,009 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11783,946,714 - 84,418,596 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01757,037,330 - 57,509,229 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11762,185,121 - 62,656,041 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1762,239,230 - 62,650,299 (+)Ensemblpanpan1.1panPan2
TANC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1911,133,634 - 11,459,738 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl911,151,475 - 11,454,022 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha912,112,386 - 12,420,462 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0912,753,835 - 13,122,957 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl912,753,841 - 13,119,057 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1911,699,638 - 12,067,930 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0915,464,054 - 15,832,278 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0915,466,810 - 15,836,349 (-)NCBIUU_Cfam_GSD_1.0
TANC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1215,453,241 - 15,813,469 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11215,448,584 - 15,813,831 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21215,435,191 - 15,618,010 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TANC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11657,849,592 - 58,254,957 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1657,855,282 - 58,306,571 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607728,468,449 - 28,937,813 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tanc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624849452,884 - 940,686 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624849452,848 - 946,511 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000009353   ⟹   ENSSTOP00000008391
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365413,744,687 - 4,115,007 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000036714   ⟹   ENSSTOP00000031302
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365413,816,253 - 3,908,663 (+)Ensembl
RefSeq Acc Id: XM_021728388   ⟹   XP_021584063
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560215,074,440 - 15,491,870 (-)NCBI
SpeTri2.0NW_0049365413,702,743 - 4,115,009 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021728390   ⟹   XP_021584065
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560215,074,440 - 15,491,870 (-)NCBI
SpeTri2.0NW_0049365413,702,743 - 4,115,009 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040268618   ⟹   XP_040124552
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560215,074,440 - 15,491,870 (-)NCBI
RefSeq Acc Id: XM_040268619   ⟹   XP_040124553
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560215,074,440 - 15,491,870 (-)NCBI
RefSeq Acc Id: XM_040268620   ⟹   XP_040124554
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560215,074,440 - 15,429,232 (-)NCBI
RefSeq Acc Id: XM_040268621   ⟹   XP_040124555
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560215,074,440 - 15,491,870 (-)NCBI
RefSeq Acc Id: XM_040268622   ⟹   XP_040124556
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560215,074,440 - 15,491,870 (-)NCBI
RefSeq Acc Id: XM_040268623   ⟹   XP_040124557
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560215,074,440 - 15,333,449 (-)NCBI
RefSeq Acc Id: XM_040268624   ⟹   XP_040124558
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560215,074,440 - 15,333,449 (-)NCBI
RefSeq Acc Id: XP_021584063   ⟸   XM_021728388
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021584065   ⟸   XM_021728390
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_040124556   ⟸   XM_040268622
- Peptide Label: isoform X7
- UniProtKB: I3MDE2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040124555   ⟸   XM_040268621
- Peptide Label: isoform X6
RefSeq Acc Id: XP_040124553   ⟸   XM_040268619
- Peptide Label: isoform X4
RefSeq Acc Id: XP_040124552   ⟸   XM_040268618
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040124554   ⟸   XM_040268620
- Peptide Label: isoform X5
RefSeq Acc Id: XP_040124558   ⟸   XM_040268624
- Peptide Label: isoform X9
RefSeq Acc Id: XP_040124557   ⟸   XM_040268623
- Peptide Label: isoform X8
Ensembl Acc Id: ENSSTOP00000008391   ⟸   ENSSTOT00000009353
Ensembl Acc Id: ENSSTOP00000031302   ⟸   ENSSTOT00000036714


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000009340 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000009353.3 UniProtKB/TrEMBL
  ENSSTOT00000036714.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  Dendritic_Spine_Reg/Scaffold UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
NCBI Gene Tanc2 ENTREZGENE
PANTHER PROTEIN TANC2 UniProtKB/TrEMBL
  ROLLING PEBBLES, ISOFORM B UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  TPR_8 UniProtKB/TrEMBL
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
  SSF48452 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A287DCK6_ICTTR UniProtKB/TrEMBL
  I3MDE2 ENTREZGENE, UniProtKB/TrEMBL